mAbs, Volume 3, Issue 3 (2011)

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mAbs, Volume 3, Issue 3 (2011)

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Editorial

Editorial
The amazing, multipurpose antibody
Alain Beck & Janice M. Reichert
Pages: 221-222
Published online: 01 May 2011
CitationforThe amazing, multipurpose antibody | Full Text | PDF (91.9 KB)
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Meeting Report

Meeting Report
Next generation and biosimilar monoclonal antibodies: Essential considerations towards regulatory acceptance in Europe; February 3-4, 2011; Freiburg, Germany
Janice M. Reichert
Pages: 223-240
Published online: 01 May 2011
AbstractforNext generation and biosimilar monoclonal antibodies: Essential considerations towards regulatory acceptance in Europe; February 3-4, 2011; Freiburg, Germany | PDF (3.1 MB)
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Commentary

Regulatory pathways in the European Union
Manuela Kohler
Pages: 241-242
Published online: 01 May 2011
AbstractforRegulatory pathways in the European Union | Full Text | PDF (424.7 KB)
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Review

Review Article
Engineering the variable region of therapeutic IgG antibodies
Tomoyuki Igawa, Hiroyuki Tsunoda, Taichi Kuramochi, Zenjiro Sampei, Shinya Ishii & Kunihiro Hattori
Pages: 243-252
Published online: 01 May 2011
AbstractforEngineering the variable region of therapeutic IgG antibodies | Full Text | References | PDF (1.8 MB)
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Review Article
Fragmentation of monoclonal antibodies
Josef Vlasak & Roxana Ionescu
Pages: 253-263
Published online: 01 May 2011
AbstractforFragmentation of monoclonal antibodies | Full Text | References | PDF (2.9 MB)
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Report

Article
A novel synthetic naïve human antibody library allows the isolation of antibodies against a new epitope of oncofetal fibronectin
Alessandra Villa, Valeria Lovato, Emil Bujak, Sarah Wulhfard, Nadine Pasche & Dario Neri
Pages: 264-272
Published online: 01 May 2011
AbstractforA novel synthetic naïve human antibody library allows the isolation of antibodies against a new epitope of oncofetal fibronectin | Full Text | References | PDF (2.3 MB) | Supplemental
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Article
A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity
Jianying Dong, Arlene Sereno, Dikran Aivazian, Emma Langley, Brian R. Miller, William B Snyder, Eric Chan, Matt Cantele, Ronald Morena, Ingrid B.J.K. Joseph, Antonio Boccia, Cyrus Virata, James Gamez, Grace Yco, Michael Favis, Xiufeng Wu, Christilyn P. Graff, Qin Wang, Ellen Rohde, Rachel Rennard, Lisa Berquist, Flora Huang, Ying Zhang, Sharon X. Gao, Steffan N. Ho, Stephen J. Demarest, Mitchell E. Reff, Kandasamy Hariharan & Scott M. Glaser
Pages: 273-288
Published online: 01 May 2011
AbstractforA stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity | Full Text | References | PDF (5.4 MB) | Supplemental
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Article
Glycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study
Ningyan Zhang, Liming Liu, Calin Dan Dumitru, Nga Rewa Houston Cummings, Michael Cukan, Youwei Jiang, Yuan Li, Fang Li, Teresa Mitchell, Muralidhar R. Mallem, Yangsi Ou, Rohan N. Patel, Kim Vo, Hui Wang, Irina Burnina, Byung-Kwon Choi, Hans E. Huber, Terrance A. Stadheim & Dongxing Zha
Pages: 289-298
Published online: 01 May 2011
AbstractforGlycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study | Full Text | References | PDF (2.9 MB) | Supplemental
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Perspective

Rational engineering of antibody therapeutics targeting multiple oncogene pathways
Jonathan Fitzgerald & Alexey A. Lugovskoy
Pages: 299-309
Published online: 01 May 2011
AbstractforRational engineering of antibody therapeutics targeting multiple oncogene pathways | Full Text | References | PDF (4.7 MB)
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Intellectual property protection
Strategies for antibody inventions
Ulrich Storz
Pages: 310-317
Published online: 01 May 2011
AbstractforIntellectual property protection | Full Text | References | PDF (1.5 MB)
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Point of View

Biosimilars 2.0
Guiding principles for a global "patients first" standard
Joseph Miletich, Geoffrey Eich, Gustavo Grampp & Barbara Mounho
Pages: 318-325
Published online: 01 May 2011
AbstractforBiosimilars 2.0 | Full Text | References | PDF (1.5 MB)
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Editor's Corner

Editorial
2011 upcoming meetings
Janice M. Reichert
Pages: 326-327
Published online: 01 May 2011
Citationfor2011 upcoming meetings | PDF (512.8 KB)
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