Prion, Volume 15, Issue 1 (2021)

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Prion, Volume 15, Issue 1 (2021)

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Research Paper

Article
Exploration of genetic factors resulting in abnormal disease in cattle experimentally challenged with bovine spongiform encephalopathy
Sandor Dudas, Renee Anderson, Antanas Staskevicus, Gordon Mitchell, James C. Cross & Stefanie Czub
Pages: 1-11
Published online: 04 Jan 2021
AbstractforExploration of genetic factors resulting in abnormal disease in cattle experimentally challenged with bovine spongiform encephalopathy | Full Text | References | PDF (1.3 MB) | EPUB
  • 2094 Views
  • 1 CrossRef citations
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Open Access

Case Report

Case Report
System degeneration in an MM1-type sporadic Creutzfeldt-Jakob disease case with an unusually prolonged akinetic mutism state
Yasushi Iwasaki, Keiko Mori, Masumi Ito, Yoshinari Kawai, Akio Akagi, Yuichi Riku, Hiroaki Miyahara, Atsushi Kobayashi, Tetsuyuki Kitamoto & Mari Yoshida
Pages: 12-20
Published online: 20 Jan 2021
AbstractforSystem degeneration in an MM1-type sporadic Creutzfeldt-Jakob disease case with an unusually prolonged akinetic mutism state | Full Text | References | PDF (11 MB) | EPUB
  • 1781 Views
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Open Access

Extra-View

Article Commentary
The expanding scope of amyloid signalling
Asen Daskalov & Sven J. Saupe
Pages: 21-28
Published online: 12 Feb 2021
AbstractforThe expanding scope of amyloid signalling | Full Text | References | PDF (440.3 KB) | EPUB
  • 1528 Views
  • 4 CrossRef citations
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Open Access

Short Communicatios

Rapid Communication
STXBP1 forms amyloid-like aggregates in rat brain and demonstrates amyloid properties in bacterial expression system
A.V. Chirinskaite, V.A. Siniukova, M.E. Velizhanina, J.V. Sopova, T.A. Belashova & S.P. Zadorsky
Pages: 29-36
Published online: 16 Feb 2021
AbstractforSTXBP1 forms amyloid-like aggregates in rat brain and demonstrates amyloid properties in bacterial expression system | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
  • 2105 Views
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Open Access
Brief Report
Monomeric α-synuclein (αS) inhibits amyloidogenesis of human prion protein (hPrP) by forming a stable αS-hPrP hetero-dimer.
Satoshi Yamashita, Yuji O. Kamatari, Ryo Honda, Ayumi Niwa, Hiroyuki Tomiata, Akira Hara & Kazuo Kuwata
Pages: 37-43
Published online: 14 Apr 2021
AbstractforMonomeric α-synuclein (αS) inhibits amyloidogenesis of human prion protein (hPrP) by forming a stable αS-hPrP hetero-dimer. | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 1725 Views
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Short Communications

Rapid Communication
Characterization of the prion protein gene in axis deer (Axis axis) and implications for susceptibility to chronic wasting disease
Matthew J. Buchholz, Emily A. Wright, Blake A. Grisham, Robert D. Bradley, Thomas L. Arsuffi & Warren C. Conway
Pages: 44-52
Published online: 09 Apr 2021
AbstractforCharacterization of the prion protein gene in axis deer (Axis axis) and implications for susceptibility to chronic wasting disease | Full Text | References | PDF (1.3 MB) | EPUB
  • 1921 Views
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Commentaries and Views

Article Commentary
Hypothesis: AA amyloidosis is a factor causing systemic complications after coronavirus disease
Alexey P. Galkin
Pages: 53-55
Published online: 20 Apr 2021
AbstractforHypothesis: AA amyloidosis is a factor causing systemic complications after coronavirus disease | Full Text | References | PDF (168 KB) | EPUB
  • 3239 Views
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Review

Development of molecular tools for diagnosis of Alzheimer’s disease that are based on detection of amyloidogenic proteins
Konstantin Y. Kulichikhin, Sergei A. Fedotov, Maria S. Rubel, Natalia M. Zalutskaya, Anastasia E. Zobnina, Oksana A. Malikova, Nikolay G. Neznanov, Yury O. Chernoff & Aleksandr A. Rubel
Pages: 56-69
Published online: 29 Apr 2021
AbstractforDevelopment of molecular tools for diagnosis of Alzheimer’s disease that are based on detection of amyloidogenic proteins | Full Text | References | PDF (2.1 MB) | EPUB
  • 7285 Views
  • 8 CrossRef citations
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Open Access

Research Paper

Article
Transcriptomic analysis of zebrafish prion protein mutants supports conserved cross-species function of the cellular prion protein
Niall Mungo Pollock, Patricia Leighton, Gavin Neil & W. Ted Allison
Pages: 70-81
Published online: 18 Jun 2021
AbstractforTranscriptomic analysis of zebrafish prion protein mutants supports conserved cross-species function of the cellular prion protein | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 1556 Views
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Open Access

Case Report

Long-term preservation of pharyngeal swallowing function in MM2-cortical-type sporadic Creutzfeldt-Jakob disease
Yuichi Hayashi, Kenjiro Kunieda, Takuya Kudo, Akio Kimura, Ichiro Fujishima & Takayoshi Shimohata
Pages: 82-86
Published online: 02 Jun 2021
AbstractforLong-term preservation of pharyngeal swallowing function in MM2-cortical-type sporadic Creutzfeldt-Jakob disease | Full Text | References | PDF (984.8 KB) | EPUB
  • 1379 Views
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Extra-Views

Article Commentary
On the reactive states of astrocytes in prion diseases
Ilia V. Baskakov
Pages: 87-93
Published online: 31 May 2021
AbstractforOn the reactive states of astrocytes in prion diseases | Full Text | References | PDF (306 KB) | EPUB
  • 2107 Views
  • 8 CrossRef citations
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Open Access

Research Paper

Article
Human prion disease surveillance in Spain, 1993-2018: an overview
Jesús De Pedro-Cuesta, Javier Almazán-Isla, Laura Tejedor-Romero, María Ruiz-Tovar, Fuencisla Avellanal, Alberto Rábano, Miguel Calero, Fernando J. García López & for the Spanish CJD Surveillance Group
Pages: 94-106
Published online: 12 Jun 2021
AbstractforHuman prion disease surveillance in Spain, 1993-2018: an overview | Full Text | References | PDF (1.3 MB) | EPUB
  • 1853 Views
  • 4 CrossRef citations
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Open Access

Case Report

Creutzfeldt–Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues
Collin C. Luk, Candace K. Mathiason, Christina D. Orrù, Gerard H. Jansen, Allison Thiele, Byron Caughey & Valerie L. Sim
Pages: 107-111
Published online: 16 Jun 2021
AbstractforCreutzfeldt–Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues | Full Text | References | PDF (1.6 MB) | EPUB
  • 1863 Views
  • 2 CrossRef citations
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Open Access

Research Paper

Article
Differential astrocyte and oligodendrocyte vulnerability in murine Creutzfeldt-Jakob disease
Pol Andrés-Benito, Margarita Carmona, Jean Yves Douet, Hervé Cassard, Olivier Andreoletti & Isidro Ferrer
Pages: 112-120
Published online: 05 Jul 2021
AbstractforDifferential astrocyte and oligodendrocyte vulnerability in murine Creutzfeldt-Jakob disease | Full Text | References | PDF (2.6 MB) | EPUB
  • 2233 Views
  • 5 CrossRef citations
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Open Access

Case Reports

Article
A Chinese patient with the clinical features of Parkinson’s disease contains a single copy of octarepeat deletion in PRNP case report
Qi Shi, Xiao-Jing Shen, Li-Ping Gao, Kang Xiao, Wei Zhou, Yuan Wang, Cao Chen & Xiao-Ping Dong
Pages: 121-125
Published online: 05 Jul 2021
AbstractforA Chinese patient with the clinical features of Parkinson’s disease contains a single copy of octarepeat deletion in PRNP case report | Full Text | References | PDF (1,021.4 KB) | EPUB
  • 1464 Views
  • 2 CrossRef citations
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Open Access

Research Paper

Article
Upregulation of brain hepcidin in prion diseases
Short title: Hepcidin and brain iron accumulation
Suman Chaudhary, Ajay Ashok, Aaron S. Wise, Neil A. Rana, Dallas McDonald, Alexander E. Kritikos, Qingzhong Kong & Neena Singh
Pages: 126-137
Published online: 05 Jul 2021
AbstractforUpregulation of brain hepcidin in prion diseases | Full Text | References | PDF (1.6 MB) | EPUB
  • 1745 Views
  • 1 CrossRef citations
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Open Access

Case Reports

Article
PART and ARTAG tauopathies at a relatively young age as a concomitant finding in sporadic Creutzfeldt-Jakob disease
Kateřina Menšíková, Radoslav Matěj, Eva Parobková, Magdalena Smětáková & Petr Kaňovský
Pages: 138-142
Published online: 05 Jul 2021
AbstractforPART and ARTAG tauopathies at a relatively young age as a concomitant finding in sporadic Creutzfeldt-Jakob disease | Full Text | References | PDF (1.2 MB) | EPUB
  • 1271 Views
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Open Access

Review

Decoding the role of coiled-coil motifs in human prion-like proteins
Molood Behbahanipour, Javier García-Pardo & Salvador Ventura
Pages: 143-154
Published online: 24 Aug 2021
AbstractforDecoding the role of coiled-coil motifs in human prion-like proteins | Full Text | References | PDF (1.1 MB) | EPUB
  • 1837 Views
  • 2 CrossRef citations
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Open Access

Research Paper

Article
Epitope-specific anti-PrP antibody toxicity: a comparative in-silico study of human and mouse prion proteins
Utpal Kumar Adhikari & Mourad Tayebi
Pages: 155-176
Published online: 10 Oct 2021
AbstractforEpitope-specific anti-PrP antibody toxicity: a comparative in-silico study of human and mouse prion proteins | Full Text | References | PDF (5.4 MB) | EPUB | Supplemental
  • 1555 Views
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Open Access

Case Report

Genetic Creutzfeldt-Jakob disease shows fatal family insomnia phenotype
Bin Chen, Shan Zhang, Ying Xiao, yingman Wu, Weiting Tang, Limin Yan, Zhengxue Zhang, Shengquan Qin, Mingming Dai & Yong You
Pages: 177-182
Published online: 05 Sep 2021
AbstractforGenetic Creutzfeldt-Jakob disease shows fatal family insomnia phenotype | Full Text | References | PDF (422.3 KB) | EPUB
  • 1475 Views
  • 2 CrossRef citations
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Open Access

Research paper

Article
Prion protein polymorphisms in Michigan white-tailed deer (Odocoileus virginianus)
Caitlin N. Ott-Conn, Julie A. Blanchong & Wes A. Larson
Pages: 183-190
Published online: 09 Nov 2021
AbstractforPrion protein polymorphisms in Michigan white-tailed deer (Odocoileus virginianus) | Full Text | References | PDF (687.6 KB) | EPUB
  • 974 Views
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Open Access

Review

The role of microglia in prion diseases and possible therapeutic targets: a literature review
Ananda Sampaio Lamenha Falcão de Melo, Juliana Louise Dias Lima, Maria Carolina Silva Malta, Natália França Marroquim, Álvaro Rivelli Moreira, Isabelle de Almeida Ladeia, Fabrizio dos Santos Cardoso, Daniel Buzaglo Gonçalves, Bruna Guimarães Dutra & Júlio César Claudino dos Santos
Pages: 191-206
Published online: 09 Nov 2021
AbstractforThe role of microglia in prion diseases and possible therapeutic targets: a literature review | Full Text | References | PDF (1.1 MB) | EPUB
  • 2236 Views
  • 4 CrossRef citations
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Open Access

Research Paper

Article
Detection of two dissimilar chronic wasting disease isolates in two captive Rocky Mountain elk (Cervus canadensis) herds
Two distinctive chronic wasting disease isolates identified in captive elk
Tracy A. Nichols, Eric M. Nicholson, Yihui Liu, Wanyun Tao, Terry R. Spraker, Michael Lavelle, Justin Fischer, Qingzhong Kong & Kurt C. VerCauteren
Pages: 207-215
Published online: 16 Dec 2021
AbstractforDetection of two dissimilar chronic wasting disease isolates in two captive Rocky Mountain elk (Cervus canadensis) herds | Full Text | References | PDF (909.4 KB) | EPUB
  • 1188 Views
  • 1 CrossRef citations
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Open Access

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