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Original Articles

The Scientific Basis of Uncertainty Factors Used in Setting Occupational Exposure Limits

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Maria Dalma Mangiapia, Iason Verginelli, Renato Baciocchi, Maria Paola Bogliolo & Simona Berardi. (2022) Review of reference values for the assessment of inhalation risks for workers at industrial contaminated sites. Human and Ecological Risk Assessment: An International Journal 28:5-6, pages 664-682.
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Emma E.J. Kasteel & Remco H.S. Westerink. (2021) Refining in vitro and in silico neurotoxicity approaches by accounting for interspecies and interindividual differences in toxicodynamics. Expert Opinion on Drug Metabolism & Toxicology 17:8, pages 1007-1017.
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Theresa E. Boots, Alyssa M. Kogel, Nathan M. Drew & Eileen D. Kuempel. (2021) Utilizing literature-based rodent toxicology data to derive potency estimates for quantitative risk assessment. Nanotoxicology 15:6, pages 740-760.
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Emily May Lent, Glenn Leach & Mark S. Johnson. (2021) Development of health-based environmental screening levels for insensitive munitions constituents. Human and Ecological Risk Assessment: An International Journal 27:6, pages 1543-1567.
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Emma Arnesdotter, Vera Rogiers, Tamara Vanhaecke & Mathieu Vinken. (2021) An overview of current practices for regulatory risk assessment with lessons learnt from cosmetics in the European Union. Critical Reviews in Toxicology 51:5, pages 395-417.
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Markus Hilpert, Vesna Ilievski, Maxine Coady, Maria Andrade-Gutierrez, Beizhan Yan, Steven N. Chillrud, Ana Navas-Acien & Norman J. Kleiman. (2019) A custom-built low-cost chamber for exposing rodents to e-cigarette aerosol: practical considerations. Inhalation Toxicology 31:11-12, pages 399-408.
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Mark D. Ihrie, Alexia J. Taylor-Just, Nigel J. Walker, Matthew D. Stout, Amit Gupta, Jamie S. Richey, Barry K. Hayden, Gregory L. Baker, Barney R. Sparrow, Katherine S. Duke & James C. Bonner. (2019) Inhalation exposure to multi-walled carbon nanotubes alters the pulmonary allergic response of mice to house dust mite allergen. Inhalation Toxicology 31:5, pages 192-202.
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Linda Schenk & Gunnar Johanson. (2018) Use of uncertainty factors by the European Commission Scientific Committee on Occupational Exposure Limits: a follow-up. Critical Reviews in Toxicology 48:7, pages 513-521.
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Martha Waters, Lauralynn McKernan, Andrew Maier, Michael Jayjock, Val Schaeffer & Lisa Brosseau. (2015) Exposure Estimation and Interpretation of Occupational Risk: Enhanced Information for the Occupational Risk Manager. Journal of Occupational and Environmental Hygiene 12:sup1, pages S99-S111.
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G. S. Dotson, A. Maier, P. D. Siegel, S. E. Anderson, B. J. Green, A. B. Stefaniak, C. D. Codispoti & I. Kimber. (2015) Setting Occupational Exposure Limits for Chemical Allergens—Understanding the Challenges. Journal of Occupational and Environmental Hygiene 12:sup1, pages S82-S98.
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Eileen D. Kuempel, Lisa M. Sweeney, John B. Morris & Annie M. Jarabek. (2015) Advances in Inhalation Dosimetry Models and Methods for Occupational Risk Assessment and Exposure Limit Derivation. Journal of Occupational and Environmental Hygiene 12:sup1, pages S18-S40.
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M. Deveau, C-P Chen, G. Johanson, D. Krewski, A. Maier, K. J. Niven, S. Ripple, P. A. Schulte, J. Silk, J. H. Urbanus, D. M. Zalk & R. W. Niemeier. (2015) The Global Landscape of Occupational Exposure Limits—Implementation of Harmonization Principles to Guide Limit Selection. Journal of Occupational and Environmental Hygiene 12:sup1, pages S127-S144.
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P. A. Schulte, C. Whittaker & C. P. Curran. (2015) Considerations for Using Genetic and Epigenetic Information in Occupational Health Risk Assessment and Standard Setting. Journal of Occupational and Environmental Hygiene 12:sup1, pages S69-S81.
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Olwenn V. Martin. (2023) Synergistic effects of chemical mixtures: How frequent is rare?. Current Opinion in Toxicology 36, pages 100424.
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Luciana Dalazen dos Santos, Tugstênio Lima de Souza, Gabriel Ian da Silva, Mateus Francescon Ferreira de Mello, Jeane Maria de Oliveira, Marco Aurelio Romano & Renata Marino Romano. (2023) Prepubertal oral exposure to relevant doses of acrylamide impairs the testicular antioxidant system in adulthood, increasing protein carbonylation and lipid peroxidation. Environmental Pollution 334, pages 122132.
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Laura L. Maurer, Melannie S. Alexander, Ammie N. Bachman, Fabian A. Grimm, R. Jeff Lewis, Colin M. North, Nancy C. Wojcik & Katy O. Goyak. (2022) An interdisciplinary framework for derivation of occupational exposure limits. Frontiers in Public Health 10.
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Jon A. Arnot, Liisa Toose, James M. Armitage, Alessandro Sangion, Alexandra Looky, Trevor N. Brown, Li Li & Richard A. Becker. (2022) Developing an internal threshold of toxicological concern (iTTC). Journal of Exposure Science & Environmental Epidemiology 32:6, pages 877-884.
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Lisa Wiesner, Selene Araya & Ester Lovsin Barle. (2022) Identifying nonhazardous substances in pharmaceutical manufacturing and setting default health‐based exposure limits (HBELs). Journal of Applied Toxicology 42:9, pages 1443-1457.
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Noor Asyikin Suaidi, Mohammed Abdullah Alshawsh, See-Ziau Hoe, Mohd Helmy Mokhtar & Siti Rosmani Md Zin. (2022) Toxicological Effects of Technical Xylene Mixtures on the Female Reproductive System: A Systematic Review. Toxics 10:5, pages 235.
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Ji-Guang Gao, Yu Jiang, Jiu-Tao Zheng & Liu-Wang Nie. (2022) Pubertal exposure to acrylamide disrupts spermatogenesis by interfering with meiotic progression in male mice. Toxicology Letters 358, pages 80-87.
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Michael Dourson, Lorna Ewart, Suzanne C Fitzpatrick, Silvia B M Barros, Brinda Mahadevan & A Wallace Hayes. (2022) The Future of Uncertainty Factors With In Vitro Studies Using Human Cells . Toxicological Sciences 186:1, pages 12-17.
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Stephen Leharne. (2021) Risk assessment and remediation of NAPL contaminated soil and groundwater. ChemTexts 8:1.
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Kuldeep Rajpoot, Nimeet Desai, HariPriya Koppisetti, Muktika Tekade, Mukesh Chandra Sharma, Santosh Kumar Behera & Rakesh Kumar Tekade. 2022. Pharmacokinetics and Toxicokinetic Considerations. Pharmacokinetics and Toxicokinetic Considerations 357 383 .
Varun Ahuja & Mohan Krishnappa. (2021) Approaches for setting occupational exposure limits in the pharmaceutical industry. Journal of Applied Toxicology 42:1, pages 154-167.
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Jillian A. Parker, Corey Boles, Amanda N. Buerger, Ernest S. Fung & Andrew Maier. (2021) Derivation of an occupational exposure limit for β-glucans. Regulatory Toxicology and Pharmacology 123, pages 104959.
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Minashree Kumari & Arun Kumar. (2021) Can pharmaceutical drugs used to treat Covid-19 infection leads to human health risk? A hypothetical study to identify potential risk. Science of The Total Environment 778, pages 146303.
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Mark Elwood. (2021) The Scientific Basis for Occupational Exposure Limits for Hydrogen Sulphide—A Critical Commentary. International Journal of Environmental Research and Public Health 18:6, pages 2866.
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Emily May Lent, Thomas E. Sussan, Glenn J. Leach & Mark S. Johnson. (2020) Using Evidence Integration Techniques in the Development of Health-Based Occupational Exposure Levels. International Journal of Toxicology 40:2, pages 178-195.
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Zhen Wang, Dan Dinh, W. Casan Scott, E. Spencer Williams, Michael Ciarlo, Paul DeLeo & Bryan W. Brooks. (2019) Critical review and probabilistic health hazard assessment of cleaning product ingredients in all-purpose cleaners, dish care products, and laundry care products. Environment International 125, pages 399-417.
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Anthony J. Streeter & Ellen C. Faria. (2017) Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits. International Journal of Hygiene and Environmental Health 220:4, pages 659-672.
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Laura C. Savery, René Viñas, Amber M. Nagy, Prachi Pradeep, Stephen J. Merrill, Alan M. Hood, Subhas G. Malghan, Peter L. Goering & Ronald P. Brown. (2017) Deriving a provisional tolerable intake for intravenous exposure to silver nanoparticles released from medical devices. Regulatory Toxicology and Pharmacology 85, pages 108-118.
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