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Review

Antibody therapeutics:

isotype and glycoform selection

Pages 1401-1413 | Published online: 29 Aug 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (31)

Thach H. Chu, Edward F. Patz$suffix/text()$suffix/text() & Margaret E. Ackerman. (2021) Coming together at the hinges: Therapeutic prospects of IgG3. mAbs 13:1.
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Lily Pei-Yao Liu-Shin, Adam Fung, Arun Malhotra & Gayathri Ratnaswamy. (2018) Evidence of disulfide bond scrambling during production of an antibody-drug conjugate. mAbs 10:8, pages 1190-1199.
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Anja Resemann, Lily Liu-Shin, Guillaume Tremintin, Arun Malhotra, Adam Fung, Fang Wang, Gayathri Ratnaswamy & Detlev Suckau. (2018) Rapid, automated characterization of disulfide bond scrambling and IgG2 isoform determination. mAbs 10:8, pages 1200-1213.
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Caroline S. Colley, Bojana Popovic, Sudharsan Sridharan, Judit E. Debreczeni, David Hargeaves, Michael Fung, Ling–Ling An, Bryan Edwards, Joanne Arnold, Elizabeth England, Laura Eghobamien, Ulf Sivars, Liz Flavell, Jonathan Renshaw, Kate Wickson, Paul Warrener, Jingying Zha, Jessica Bonnell, Rob Woods, Trevor Wilkinson, Claire Dobson & Tristan J. Vaughan. (2018) Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors. mAbs 10:1, pages 104-117.
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Danlin Yang, Rachel Kroe-Barrett, Sanjaya Singh, Christopher J. Roberts & Thomas M. Laue. (2017) IgG cooperativity – Is there allostery? Implications for antibody functions and therapeutic antibody development. mAbs 9:8, pages 1231-1252.
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Giuseppe Della Pepa, Lutgarda Bozzetto, Giovanni Annuzzi & Angela Albarosa Rivellese. (2017) Alirocumab for the treatment of hypercholesterolaemia. Expert Review of Clinical Pharmacology 10:6, pages 571-582.
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Saman Soleimanpour, Tahereh Hassannia, Mahdieh Motiee, Abbas Ali Amini & S. A. R. Rezaee. (2017) Fcγ1 fragment of IgG1 as a powerful affinity tag in recombinant Fc-fusion proteins: immunological, biochemical and therapeutic properties. Critical Reviews in Biotechnology 37:3, pages 371-392.
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Nazzareno Dimasi, Ryan Fleming, Kris F. Sachsenmeier, Binyam Bezabeh, Carl Hay, Jincheng Wu, Erin Sult, Saravanan Rajan, Li Zhuang, Peter Cariuk, Andrew Buchanan, Michael A. Bowen, Herren Wu & Changshou Gao. (2017) Guiding bispecific monovalent antibody formation through proteolysis of IgG1 single-chain. mAbs 9:3, pages 438-454.
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Nicola Ferri, Alberto Corsini, Cesare R. Sirtori & Massimiliano Ruscica. (2017) Bococizumab for the treatment of hypercholesterolaemia. Expert Opinion on Biological Therapy 17:2, pages 237-243.
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Leonid Dubrovsky, Elliott Joseph Brea, Dmitry Pankov, Emily Casey, Tao Dao, Cheng Liu & David A. Scheinberg. (2016) Mechanisms of leukemia resistance to antibody dependent cellular cytotoxicity. OncoImmunology 5:9.
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Paul W Tebbey, Amy Varga, Michael Naill, Jerry Clewell & Jaap Venema. (2015) Consistency of quality attributes for the glycosylated monoclonal antibody Humira® (adalimumab). mAbs 7:5, pages 805-811.
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Michelle Kinder, Allison R Greenplate, William R Strohl, Robert E Jordan & Randall J Brezski. (2015) An Fc engineering approach that modulates antibody-dependent cytokine release without altering cell-killing functions. mAbs 7:3, pages 494-504.
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Zenjiro Sampei, Tomoyuki Igawa, Tetsuhiro Soeda, Miho Funaki, Kazutaka Yoshihashi, Takehisa Kitazawa, Atsushi Muto, Tetsuo Kojima, Satoshi Nakamura & Kunihiro Hattori. (2015) Non–antigen-contacting region of an asymmetric bispecific antibody to factors IXa/X significantly affects factor VIII-mimetic activity. mAbs 7:1, pages 120-128.
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Randall J Brezski, Michelle Kinder, Katharine D Grugan, Keri L Soring, Jill Carton, Allison R Greenplate, Theodore Petley, Dorie Capaldi, Kerry Brosnan, Eva Emmell, Sharon Watson & Robert E Jordan. (2014) A monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo. mAbs 6:5, pages 1265-1273.
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Martin Oaks, Samuel Taylor & James Shaffer. (2013) Autoantibodies targeting tumor-associated antigens in metastatic cancer. OncoImmunology 2:6.
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Ian C. Wilkinson, Susan B. Fowler, LeeAnn Machiesky, Kenneth Miller, David B. Hayes, Morshed Adib, Cheng Her, M. Jack Borrok, Ping Tsui, Matthew Burrell, Dominic J. Corkill, Susanne Witt, David C. Lowe & Carl I. Webster. (2013) Monovalent IgG4 molecules. mAbs 5:3, pages 406-417.
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Marcella Yu, Darren Brown, Chae Reed, Shan Chung, Jeff Lutman, Eric Stefanich, Anne Wong, Jean-Philippe Stephan & Robert Bayer. (2012) Production, characterization and pharmacokinetic properties of antibodies with N-linked Mannose-5 glycans. mAbs 4:4, pages 475-487.
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B. Nagels, K. Weterings, N. Callewaert & E. J. M. Van Damme. (2012) Production of Plant Made Pharmaceuticals: From Plant Host to Functional Protein. Critical Reviews in Plant Sciences 31:2, pages 148-180.
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Randall J. Brezski, Allison Oberholtzer, Brandy Strake & Robert E. Jordan. (2011) The in vitro resistance of IgG2 to proteolytic attack concurs with a comparative paucity of autoantibodies against peptide analogs of the IgG2 hinge. mAbs 3:6, pages 558-567.
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Philippe Taupin. (2011) Modulation of GDP-fucose level for generating proteins with reduced rate of fucosylation (WO2010141855). Expert Opinion on Therapeutic Patents 21:9, pages 1497-1499.
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Philippe Taupin. (2011) Cell lines expressing mutant FX proteins to generate proteins with reduced rate of fucosylation: WO2010/141478. Expert Opinion on Therapeutic Patents 21:7, pages 1143-1146.
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Michael F. Naso, Susan H. Tam, Bernard J. Scallon & T. Shantha Raju. (2010) Engineering host cell lines to reduce terminal sialylation of secreted antibodies. mAbs 2:5, pages 519-527.
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Dirk Chelius, Peter Ruf, Patrick Gruber, Matthias Plöscher, Reinhard Liedtke, Eva Gansberger, Juergen Hess, Michael Wasiliu & Horst Lindhofer. (2010) Structural and functional characterization of the trifunctional antibody catumaxomab. mAbs 2:3, pages 309-319.
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Frank R. Brennan, Laura Dill Morton, Sebastian Spindeldreher, Andrea Kiessling, Roy Allenspach, Adam Hey, Patrick Müller, Werner Frings & Jennifer Sims. (2010) Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies. mAbs 2:3, pages 233-255.
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Randall J. Brezski & Robert E. Jordan. (2010) Cleavage of IgGs by proteases associated with invasive diseases. mAbs 2:3, pages 212-220.
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Roy Jefferis & Marie-Paule Lefranc. (2009) Human immunoglobulin allotypes. mAbs 1:4, pages 332-338.
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Xiaoling Wang, Tapan K. Das, Satish K. Singh & Sandeep Kumar. (2009) Potential aggregation prone regions in biotherapeutics. mAbs 1:3, pages 254-267.
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Roy Jefferis. (2009) The antibody paradigm: present and future development as a scaffold for biopharmaceutical drugs. Biotechnology and Genetic Engineering Reviews 26:1, pages 1-42.
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Roy Jefferis. (2009) Aglycosylated antibodies and the methods of making and using them: WO2008030564. Expert Opinion on Therapeutic Patents 19:1, pages 101-105.
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Eszter Nagy, Carmen Giefing & Alexander von Gabain. (2008) Anti-infective antibodies: a novel tool to prevent and treat nosocomial diseases. Expert Review of Anti-infective Therapy 6:1, pages 21-30.
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Crossref
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Crossref
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Crossref
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Crossref
Esther M. Vletter, Marvyn T. Koning, Hans Ulrich Scherer, Hendrik Veelken & Rene E. M. Toes. (2020) A Comparison of Immunoglobulin Variable Region N-Linked Glycosylation in Healthy Donors, Autoimmune Disease and Lymphoma. Frontiers in Immunology 11.
Crossref
Liriye Kurtovic, Michelle J. Boyle, D. Herbert Opi, Alexander T. Kennedy, Wai‐Hong Tham, Linda Reiling, Jo‐Anne Chan & James G. Beeson. (2019) Complement in malaria immunity and vaccines. Immunological Reviews 293:1, pages 38-56.
Crossref
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Crossref
Feroz Jameel, Brittney J. Mills, Ehab M. Moussa, Vikram Sisodiya, Tony Cano & Anthony R. Haight. 2020. Development of Biopharmaceutical Drug-Device Products. Development of Biopharmaceutical Drug-Device Products 27 48 .
David N. Powers, Nicholas Trunfio, Sai R. Velugula‐Yellela, Phillip Angart, Anneliese Faustino & Cyrus Agarabi. (2019) Multivariate data analysis of growth medium trends affecting antibody glycosylation. Biotechnology Progress 36:1.
Crossref
David N. Powers, Yifan Wang, Erica J. Fratz‐Berilla, Sai Rashmika Velugula‐Yellela, Brittany Chavez, Phillip Angart, Nicholas Trunfio, Seongkyu Yoon & Cyrus Agarabi. (2019) Real‐time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality. Biotechnology Progress 35:6.
Crossref
Bo Chen, Xin Shi, Yanping Cui, Aiping Hou & Pengjun Zhao. (2019) A Review of PCSK9 Inhibitors and their Effects on Cardiovascular Diseases. Current Topics in Medicinal Chemistry 19:20, pages 1790-1817.
Crossref
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Crossref
Zhiyuan Sun, Qinqin Ji, Adam R. Evans, Michael J. Lewis, Jingjie Mo & Ping Hu. (2019) High-throughput LC-MS quantitation of cell culture metabolites. Biologicals 61, pages 44-51.
Crossref
Simone Dudek, Sabrina Weißmüller, Martina Anzaghe, Lilija Miller, Sarah Sterr, Katja Hoffmann, Hartmut Hengel & Zoe Waibler. (2019) Human Fcγ receptors compete for TGN1412 binding that determines the antibody's effector function. European Journal of Immunology 49:7, pages 1117-1126.
Crossref
Meghdad Abdollahpour‐Alitappeh, Majid Lotfinia, Tohid Gharibi, Jalal Mardaneh, Behrouz Farhadihosseinabadi, Pegah Larki, Babak Faghfourian, Koushan Sineh Sepehr, Kazem Abbaszadeh‐Goudarzi, Ghasem Abbaszadeh‐Goudarzi, Behrooz Johari, Mohammad Reza Zali & Nader Bagheri. (2018) Antibody–drug conjugates (ADCs) for cancer therapy: Strategies, challenges, and successes. Journal of Cellular Physiology 234:5, pages 5628-5642.
Crossref
Haichao Tang, Yan Liu, Zhaojin Yu, Mingli Sun, Lu Lin, Wensi Liu, Qiang Han, Minjie Wei & Ying Jin. (2019) The Analysis of Key Factors Related to ADCs Structural Design. Frontiers in Pharmacology 10.
Crossref
Wenyan Wang, Lina Dong, Heyuan Sun, Limeng Zhu & Wanhui Liu. (2019) Development and validation of indirect and generic immunoassays to quantify free and total evolocumab in rat serum. Bioanalysis 11:8, pages 679-687.
Crossref
Mohsen Karbalaei Zadeh Babaki, Mahboubeh Taghiabadi, Saman Soleimanpour, Masoud Saleh Moghadam, Arman Mosavat, Abbas Ali Amini, Ali Mohammadi & Seyed Abdolrahim Rezaee. (2019) Mycobacterium tuberculosis Ag85b:hfcγ1 recombinant fusion protein as a selective receptor-dependent delivery system for antigen presentation. Microbial Pathogenesis 129, pages 68-73.
Crossref
Natalie K. Garcia, Galahad Deperalta & Aaron T. Wecksler. (2019) Current Trends in Biotherapeutic Higher Order Structure Characterization by Irreversible Covalent Footprinting Mass Spectrometry. Protein & Peptide Letters 26:1, pages 35-43.
Crossref
Yiran Zhang, Chun Fan, Lijuan Zhang & Xuexiao Ma. 2019. Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B. Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B 471 485 .
Meng Zhang, Huaiqian Dou, Dandan Yang, Ming Shan, Xiulian Li, Cui Hao, Yiran Zhang, Pengjiao Zeng, Yanli He, Yong Liu, Jing Fu, Wei Wang, Minghui Hu, Hui Li, Qingwu Tian, Shuhe Lei & Lijuan Zhang. 2019. Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A. Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A 141 163 .
Frank R. Brennan, Emma Smith & Sherri Dudal. 2019. Nijkamp and Parnham's Principles of Immunopharmacology. Nijkamp and Parnham's Principles of Immunopharmacology 369 406 .
Chenfei Yu, Juan Tang, Axel Loredo, Yuda Chen, Sung Yun Jung, Antrix Jain, Aviva Gordon & Han Xiao. (2018) Proximity-Induced Site-Specific Antibody Conjugation. Bioconjugate Chemistry 29:11, pages 3522-3526.
Crossref
E. N. Ilina, O. N. Solopova, D. S. Balabashin, M. V. Larina, T. K. Aliev, T. V. Grebennikova, M. A. Losich, O. N. Zaykova, P. G. Sveshnikov, D. A. Dolgikh & M. P. Kirpichnikov. (2019) Generation and Characterization of a Neutralizing Monoclonal Antibody Against Rabies Virus. Russian Journal of Bioorganic Chemistry 44:6, pages 695-704.
Crossref
Qiong Wang, Cheng‐Yu Chung, Sandra Chough & Michael J. Betenbaugh. (2018) Antibody glycoengineering strategies in mammalian cells. Biotechnology and Bioengineering 115:6, pages 1378-1393.
Crossref
Andrew Lucas, Lauren Price, Allison Schorzman, Mallory Storrie, Joseph Piscitelli, Juan Razo & William Zamboni. (2018) Factors Affecting the Pharmacology of Antibody–Drug Conjugates. Antibodies 7:1, pages 10.
Crossref
Vladimir M. Tischenko, Vladimir P. Zav’yalov & Sergey N. Ryazantsev. (2017) Human myeloma IgG4 reveals relatively rigid asymmetric Y-like structure with different conformational stability of C H 2 domains. Molecular Immunology 92, pages 199-210.
Crossref
Philip W. Howard. 2017. Protein Therapeutics. Protein Therapeutics 271 309 .
Shan Chung, Van Nguyen, Yuwen Linda Lin, Lynn Kamen & An Song. (2017) Thaw-and-use target cells pre-labeled with calcein AM for antibody-dependent cell-mediated cytotoxicity assays. Journal of Immunological Methods 447, pages 37-46.
Crossref
Regan Stephenson & Ankur Singh. (2017) Drug discovery and therapeutic delivery for the treatment of B and T cell tumors. Advanced Drug Delivery Reviews 114, pages 285-300.
Crossref
John M. Finke & William A. Banks. (2017) Modulators of IgG penetration through the blood-brain barrier: Implications for Alzheimer's disease immunotherapy. Human Antibodies 25:3-4, pages 131-146.
Crossref
Bernd Moritz & Jan Olaf Stracke. (2017) Assessment of disulfide and hinge modifications in monoclonal antibodies. ELECTROPHORESIS 38:6, pages 769-785.
Crossref
Gaowei Fan & Jinming Li. 2017. Recombinant Antibodies for Infectious Diseases. Recombinant Antibodies for Infectious Diseases 207 220 .
Zuzana Tatar, Carole Migne, Melanie Petera, Philippe Gaudin, Thierry Lequerre, Hubert Marotte, Jacques Tebib, Estelle Pujos Guillot & Martin Soubrier. (2016) Variations in the metabolome in response to disease activity of rheumatoid arthritis. BMC Musculoskeletal Disorders 17:1.
Crossref
Susan A Brooks. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences 1 16 .
P. V. Postnikov, G. I. Krotov, Yu. A. EfimovaM. A. Dikunets. (2016) IDENTIFICATION OF EPO-Fс FUSION PROTEIN BY MEANS OF POLYACRYLAMIDE GEL-ELECTROPHORESIS WITH ISOELECTROFOCUSING (IEF-PAGE)AND IN PRESENCE OF SODIUM DODECYLSULPHATE (SDS-PAGE)/ LAUROYLSARCOSINATE (SAR-PAGE) FOR THE PURPOSE OF ANTI-DOPING CONTROL. Fine Chemical Technologies 11:5, pages 70-80.
Crossref
Joannes F.M. Jacobs, Ron A. Wevers, Dirk J. Lefeber & Monique van Scherpenzeel. (2016) Fast, robust and high-resolution glycosylation profiling of intact monoclonal IgG antibodies using nanoLC-chip-QTOF. Clinica Chimica Acta 461, pages 90-97.
Crossref
Nadja Alt, Taylor Y. Zhang, Paul Motchnik, Ron Taticek, Valerie Quarmby, Tilman Schlothauer, Hermann Beck, Thomas Emrich & Reed J. Harris. (2016) Determination of critical quality attributes for monoclonal antibodies using quality by design principles. Biologicals 44:5, pages 291-305.
Crossref
S. Giuntini, D. M. Granoff, P. T. Beernink, O. Ihle, D. Bratlie & T. E. Michaelsen. (2016) Human IgG1, IgG3, and IgG3 Hinge-Truncated Mutants Show Different Protection Capabilities against Meningococci Depending on the Target Antigen and Epitope Specificity. Clinical and Vaccine Immunology 23:8, pages 698-706.
Crossref
Ngoc Phuong Lan Le, Thomas A. Bowden, Weston B. Struwe & Max Crispin. (2016) Immune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodies. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:8, pages 1655-1668.
Crossref
M H C Biermann, G Griffante, M J Podolska, S Boeltz, J St?rmer, L E Mu?oz, R Bilyy & M Herrmann. (2016) Sweet but dangerous ? the role of immunoglobulin G glycosylation in autoimmunity and inflammation. Lupus 25:8, pages 934-942.
Crossref
Mark L Chiu & Gary L Gilliland. (2016) Engineering antibody therapeutics. Current Opinion in Structural Biology 38, pages 163-173.
Crossref
Youxin Wang, Lucija Klarić, Xinwei Yu, Kujtim Thaqi, Jing Dong, Mislav Novokmet, Jim Wilson, Ozren Polasek, Youqin Liu, Jasminka Krištić, Siqi Ge, Maja Pučić-Baković, Lijuan Wu, Yong Zhou, Ivo Ugrina, Manshu Song, Jie Zhang, Xiuhua Guo, Qiang Zeng, Igor Rudan, Harry Campbell, Yurii Aulchenko, Gordan Lauc & Wei Wang. (2016) The Association Between Glycosylation of Immunoglobulin G and Hypertension. Medicine 95:17, pages e3379.
Crossref
Alison E. Mahan, Madeleine F. Jennewein, Todd Suscovich, Kendall Dionne, Jacquelynne Tedesco, Amy W. Chung, Hendrik Streeck, Maria Pau, Hanneke Schuitemaker, Don Francis, Patricia Fast, Dagna Laufer, Bruce D. Walker, Lindsey Baden, Dan H. Barouch & Galit Alter. (2016) Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination. PLOS Pathogens 12:3, pages e1005456.
Crossref
Fleur S. van de Bovenkamp, Lise Hafkenscheid, Theo Rispens & Yoann Rombouts. (2016) The Emerging Importance of IgG Fab Glycosylation in Immunity. The Journal of Immunology 196:4, pages 1435-1441.
Crossref
Murli Krishna & Steven G. Nadler. (2016) Immunogenicity to Biotherapeutics – The Role of Anti-drug Immune Complexes. Frontiers in Immunology 7.
Crossref
Aizhan Tastanova, Alexandra Schulz, Marc Folcher, Anne Tolstrup, Anja Puklowski, Hitto Kaufmann & Martin Fussenegger. (2016) Overexpression of YY1 increases the protein production in mammalian cells. Journal of Biotechnology 219, pages 72-85.
Crossref
Katja Walpurgis, Andreas Thomas, Wilhelm Schänzer & Mario Thevis. (2016) Myostatin inhibitors in sports drug testing: Detection of myostatin-neutralizing antibodies in plasma/serum by affinity purification and Western blotting. PROTEOMICS - Clinical Applications 10:2, pages 195-205.
Crossref
Jude C. Lakbub, Daniel F. Clark, Ishan S. Shah, Zhikai Zhu, Xiaomeng Su, Eden P. Go, Thomas J. Tolbert & Heather Desaire. (2016) Disulfide bond characterization of endogenous IgG3 monoclonal antibodies using LC-MS: an investigation of IgG3 disulfide-mediated isoforms. Analytical Methods 8:31, pages 6046-6055.
Crossref
Yusuke Mimura, Ronan M. Kelly, Louise Unwin, Simone Albrecht, Roy Jefferis, Margaret Goodall, Yoichi Mizukami, Yuka Mimura-Kimura, Tsuneo Matsumoto, Hiroshi Ueoka & Pauline M. Rudd. (2016) Enhanced sialylation of a human chimeric IgG1 variant produced in human and rodent cell lines. Journal of Immunological Methods 428, pages 30-36.
Crossref
Jennifer D. Könitzer, Annette Sieron, Angelika Wacker & Barbara Enenkel. (2015) Reformatting Rituximab into Human IgG2 and IgG4 Isotypes Dramatically Improves Apoptosis Induction In Vitro. PLOS ONE 10:12, pages e0145633.
Crossref
Stephanie Kapelski, Alexander Boes, Holger Spiegel, Melanie de Almeida, Torsten Klockenbring, Andreas Reimann, Rainer Fischer, Stefan Barth & Rolf Fendel. (2015) Fast track antibody V-gene rescue, recombinant expression in plants and characterization of a PfMSP4-specific antibody. Malaria Journal 14:1.
Crossref
Ningyan Zhang, Hui Deng, Xuejun Fan, Anneliese Gonzalez, Songlin Zhang, Randall J. Brezski, Byung-Kwon Choi, Michael Rycyzyn, William Strohl, Robert Jordan & Zhiqiang An. (2015) Dysfunctional Antibodies in the Tumor Microenvironment Associate with Impaired Anticancer Immunity. Clinical Cancer Research 21:23, pages 5380-5390.
Crossref
Jinghua Lu & Peter D. Sun. (2015) Structural mechanism of high affinity Fcγ RI recognition of immunoglobulin G . Immunological Reviews 268:1, pages 192-200.
Crossref
Satish K. Singh, Donna L. Luisi & Roger H. Pak. (2015) Antibody-Drug Conjugates: Design, Formulation and Physicochemical Stability. Pharmaceutical Research 32:11, pages 3541-3571.
Crossref
Vashti Irani, Andrew J. Guy, Dean Andrew, James G. Beeson, Paul A. Ramsland & Jack S. Richards. (2015) Molecular properties of human IgG subclasses and their implications for designing therapeutic monoclonal antibodies against infectious diseases. Molecular Immunology 67:2, pages 171-182.
Crossref
Christina PetersStuart Brown. (2015) Antibody–drug conjugates as novel anti-cancer chemotherapeutics. Bioscience Reports 35:4.
Crossref
Masaki Kurogochi, Masako Mori, Kenji Osumi, Mami Tojino, Shu-ichi Sugawara, Shou Takashima, Yuriko Hirose, Wataru Tsukimura, Mamoru Mizuno, Junko Amano, Akio Matsuda, Masahiro Tomita, Atsushi Takayanagi, Shin-Ichiro Shoda & Takashi Shirai. (2015) Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities. PLOS ONE 10:7, pages e0132848.
Crossref
Kin-Ming Lo, Olivier Leger & Björn Hock. 2015. Antibodies for Infectious Diseases. Antibodies for Infectious Diseases 319 343 .
Brian A. Baldo. (2015) Chimeric Fusion Proteins Used for Therapy: Indications, Mechanisms, and Safety. Drug Safety 38:5, pages 455-479.
Crossref
Yuzhou Fan, Ioscani Jimenez Del Val, Christian Müller, Jette Wagtberg Sen, Søren Kofoed Rasmussen, Cleo Kontoravdi, Dietmar Weilguny & Mikael Rørdam Andersen. (2014) Amino acid and glucose metabolism in fed‐batch CHO cell culture affects antibody production and glycosylation. Biotechnology and Bioengineering 112:3, pages 521-535.
Crossref
Jiang Gu, Yu Lei, Yuanping Huang, Yingying Zhao, Jing Li, Tao Huang, Junjun Zhang, Juping Wang, Xiaodong Deng, Zhengshan Chen, Christine Korteweg, Ruishu Deng, Meiling Yan, Qian Xu, Shengnan Dong, Monghong Cai, Lili Luo, Guowei Huang, Yun Wang, Qian Li, Changmei Lin, Meng Su, Chunzhang Yang & Zhengping Zhuang. (2015) Fab fragment glycosylated IgG may play a central role in placental immune evasion. Human Reproduction 30:2, pages 380-391.
Crossref
Randall J. Brezski. 2015. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies 125 146 .
Tianlei Ying, Rui Gong, Tina W. Ju, Ponraj Prabakaran & Dimiter S. Dimitrov. (2014) Engineered Fc based antibody domains and fragments as novel scaffolds. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1844:11, pages 1977-1982.
Crossref
Anne‐Sophie Dugast, Leonidas Stamatatos, Andrew Tonelli, Todd J. Suscovich, Anna F. Licht, Iliyana Mikell, Margaret E. Ackerman, Hendrik Streeck, P. J. Klasse, John P. Moore & Galit Alter. (2014) Independent evolution of Fc‐ and Fab‐mediated HIV‐1‐specific antiviral antibody activity following acute infection. European Journal of Immunology 44:10, pages 2925-2937.
Crossref
Frank R. Brennan. 2014. Handbook of Therapeutic Antibodies. Handbook of Therapeutic Antibodies 927 968 .
Susanne D. Pippig, Carsten Brockmeyer & Robert E. Zoubek. 2014. Handbook of Therapeutic Antibodies. Handbook of Therapeutic Antibodies 681 704 .
Xinsheng Tian, Annette E. Langkilde, Matthias Thorolfsson, Hanne B. Rasmussen & Bente Vestergaard. (2014) Small-Angle X-ray Scattering Screening Complements Conventional Biophysical Analysis: Comparative Structural and Biophysical Analysis of Monoclonal Antibodies IgG1, IgG2, and IgG4. Journal of Pharmaceutical Sciences 103:6, pages 1701-1710.
Crossref
V. M. Tishchenko. (2014) Relations between macro- and microstability of CH2 domains and human IgG2 and their biological activity: 1. Analysis of calorimetric and optical melting curves. Molecular Biology 48:3, pages 414-423.
Crossref
Frank R. Brennan, Annick Cauvin, Jay Tibbitts & Alison Wolfreys. (2014) Optimized Nonclinical Safety Assessment Strategies Supporting Clinical Development of Therapeutic Monoclonal Antibodies Targeting Inflammatory Diseases. Drug Development Research, pages n/a-n/a.
Crossref
Catherine J. Strietzel, Lisa M. Bergeron, Theodore Oliphant, Veronica T. Mutchler, Leszek J. Choromanski & Graeme Bainbridge. (2014) In Vitro functional characterization of feline IgGs. Veterinary Immunology and Immunopathology 158:3-4, pages 214-223.
Crossref
Amy W. ChungMusie GhebremichaelHannah RobinsonEric BrownIckwon ChoiSophie LaneAnne-Sophie DugastMatthew K. SchoenMorgane RollandTodd J. SuscovichAlison E. MahanLarry LiaoHendrik StreeckCharla AndrewsSupachai Rerks-NgarmSorachai NitayaphanMark S. de SouzaJaranit KaewkungwalPunnee PitisuttithumDonald FrancisNelson L. MichaelJerome H. KimChris Bailey-KelloggMargaret E. AckermanGalit Alter. (2014) Polyfunctional Fc-Effector Profiles Mediated by IgG Subclass Selection Distinguish RV144 and VAX003 Vaccines. Science Translational Medicine 6:228.
Crossref
Anna Perols & Amelie Eriksson Karlström. (2014) Site-Specific Photoconjugation of Antibodies Using Chemically Synthesized IgG-Binding Domains. Bioconjugate Chemistry 25:3, pages 481-488.
Crossref
Falk Nimmerjahn. (2014) Molecular and Cellular Pathways of Immunoglobulin G Activity In Vivo. ISRN Immunology 2014, pages 1-13.
Crossref
Kin-Ming Lo, Olivier Leger & Björn Hock. (2014) Antibody Engineering. Microbiology Spectrum 2:1.
Crossref
Omid Vafa, Gary L. Gilliland, Randall J. Brezski, Brandy Strake, Teresa Wilkinson, Eilyn R. Lacy, Bernard Scallon, Alexey Teplyakov, Thomas J. Malia & William R. Strohl. (2014) An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations. Methods 65:1, pages 114-126.
Crossref
Lisa M. Bergeron, Erin E. McCandless, Steve Dunham, Bill Dunkle, Yaqi Zhu, John Shelly, Sandra Lightle, Andrea Gonzales & Graeme Bainbridge. (2014) Comparative functional characterization of canine IgG subclasses. Veterinary Immunology and Immunopathology 157:1-2, pages 31-41.
Crossref
Xiaojie Yu, Kavitha Baruah, Christopher N. Scanlan & Max Crispin. 2014. Antibody Fc. Antibody Fc 179 194 .
Kory L. Alderson, Amy K. Erbe, Margaret Boyden & Paul M. Sondel. 2014. Advances in Tumor Immunology and Immunotherapy. Advances in Tumor Immunology and Immunotherapy 213 235 .
Jingcao Huang, Shuiliang Wang, Hui Lyu, Bo Cai, XiaoHe Yang, Jianxiang Wang & Bolin Liu. (2013) The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells. Molecular Cancer 12:1.
Crossref
Yajun Jennifer Wang & Brian Hosken. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia 1 38 .
Margaret Doherty, Jonathan Bones, Niaobh McLoughlin, Jayne E. Telford, Bryan Harmon, Michael R. DeFelippis & Pauline M. Rudd. (2013) An automated robotic platform for rapid profiling oligosaccharide analysis of monoclonal antibodies directly from cell culture. Analytical Biochemistry 442:1, pages 10-18.
Crossref
Takahiko Ito & Kouhei Tsumoto. (2013) Effects of subclass change on the structural stability of chimeric, humanized, and human antibodies under thermal stress. Protein Science 22:11, pages 1542-1551.
Crossref
V. Berger, F. Richter, K. Zettlitz, F. Unverdorben, P. Scheurich, A. Herrmann, K. Pfizenmaier & R. E. Kontermann. (2013) An anti-TNFR1 scFv-HSA fusion protein as selective antagonist of TNF action. Protein Engineering Design and Selection 26:10, pages 581-587.
Crossref
Michelle Kinder, Allison R. Greenplate, Katharine D. Grugan, Keri L. Soring, Katharine A. Heeringa, Stephen G. McCarthy, Gregory Bannish, Meredith Perpetua, Frank Lynch, Robert E. Jordan, William R. Strohl & Randall J. Brezski. (2013) Engineered Protease-resistant Antibodies with Selectable Cell-killing Functions. Journal of Biological Chemistry 288:43, pages 30843-30854.
Crossref
Sergey Ryazantsev, Vladimir Tischenko, Christopher Nguyen, Vyacheslav Abramov & Vladimir Zav'yalov. (2013) Three-Dimensional Structure of the Human Myeloma IgG2. PLoS ONE 8:6, pages e64076.
Crossref
Lisa M. Jones, Hao Zhang, Weidong Cui, Sandeep Kumar, Justin B. Sperry, James A. Carroll & Michael L. Gross. (2013) Complementary MS Methods Assist Conformational Characterization of Antibodies with Altered S–S Bonding Networks. Journal of the American Society for Mass Spectrometry 24:6, pages 835-845.
Crossref
Takuro Noguchi, Gerd Ritter & Hiroyoshi Nishikawa. (2013) Antibody-based therapy in colorectal cancer. Immunotherapy 5:5, pages 533-545.
Crossref
A. C. Vestrheim, A. Moen, W. Egge-Jacobsen, D. B. Bratlie & T. E. Michaelsen. (2013) Different Glycosylation Pattern of Human IgG1 and IgG3 Antibodies Isolated from Transiently as well as Permanently Transfected Cell Lines. Scandinavian Journal of Immunology 77:5, pages 419-428.
Crossref
Anja Lux, Xiaojie Yu, Chris N. Scanlan & Falk Nimmerjahn. (2013) Impact of Immune Complex Size and Glycosylation on IgG Binding to Human FcγRs. The Journal of Immunology 190:8, pages 4315-4323.
Crossref
Chichi Huang & Ronald V. Swanson. 2013. Fusion Protein Technologies for Biopharmaceuticals. Fusion Protein Technologies for Biopharmaceuticals 123 142 .
Christian A. Gerdes, Valeria Gonzalez Nicolini, Sylvia Herter, Erwin van Puijenbroek, Sabine Lang, Michaela Roemmele, Ekkehard Moessner, Olivier Freytag, Thomas Friess, Carola H. Ries, Birgit Bossenmaier, Hans Joachim Mueller & Pablo Umaña. (2013) GA201 (RG7160): A Novel, Humanized, Glycoengineered Anti-EGFR Antibody with Enhanced ADCC and Superior In Vivo Efficacy Compared with Cetuximab . Clinical Cancer Research 19:5, pages 1126-1138.
Crossref
Dmitrij Hristodorov, Rainer Fischer, Hannah Joerissen, Beate M?ller-Tiemann, Heiner Apeler & Lars Linden. (2012) Generation and Comparative Characterization of Glycosylated and Aglycosylated Human IgG1 Antibodies. Molecular Biotechnology 53:3, pages 326-335.
Crossref
Miroslav Dostalek, Iain Gardner, Brian M. Gurbaxani, Rachel H. Rose & Manoranjenni Chetty. (2013) Pharmacokinetics, Pharmacodynamics and Physiologically-Based Pharmacokinetic Modelling of Monoclonal Antibodies. Clinical Pharmacokinetics 52:2, pages 83-124.
Crossref
Kumiko Sakai-Kato, Kunie Nanjo, Teruhide Yamaguchi, Haruhiro Okuda & Toru Kawanishi. (2013) High-performance liquid chromatography separation of monoclonal IgG2 isoforms on a column packed with nonporous particles. Analytical Methods 5:21, pages 5899.
Crossref
Falk Nimmerjahn. 2013. Molecular and Cellular Mechanisms of Antibody Activity. Molecular and Cellular Mechanisms of Antibody Activity 113 138 .
Stefan Ståhl, Nina Kronqvist, Andreas Jonsson & John Löfblom. (2013) Affinity proteins and their generation. Journal of Chemical Technology & Biotechnology 88:1, pages 25-38.
Crossref
Ray Bakhtiar. (2012) Therapeutic Recombinant Monoclonal Antibodies. Journal of Chemical Education 89:12, pages 1537-1542.
Crossref
Thomas A. Bowden, Kavitha Baruah, Charlotte H. Coles, David J. Harvey, Xiaojie Yu, Byeong-Doo Song, David I. Stuart, A. Radu Aricescu, Christopher N. Scanlan, E. Yvonne Jones & Max Crispin. (2012) Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped during Glycan Biosynthesis. Journal of the American Chemical Society 134:42, pages 17554-17563.
Crossref
Marije B. Overdijk, Sandra Verploegen, Antonio Ortiz Buijsse, Tom Vink, Jeanette H. W. Leusen, Wim K. Bleeker & Paul W. H. I. Parren. (2012) Crosstalk between Human IgG Isotypes and Murine Effector Cells. The Journal of Immunology 189:7, pages 3430-3438.
Crossref
Swaminathan Sethu, Karthik Govindappa, Mohammad Alhaidari, Munir Pirmohamed, Kevin Park & Jean Sathish. (2012) Immunogenicity to Biologics: Mechanisms, Prediction and Reduction. Archivum Immunologiae et Therapiae Experimentalis 60:5, pages 331-344.
Crossref
Daniel M. Czajkowsky, Jun Hu, Zhifeng Shao & Richard J. Pleass. (2012) Fc‐fusion proteins: new developments and future perspectives. EMBO Molecular Medicine 4:10, pages 1015-1028.
Crossref
Paul M. Sondel & Stephen D. Gillies. (2012) Current and Potential Uses of Immunocytokines as Cancer Immunotherapy. Antibodies 1:2, pages 149-171.
Crossref
Yi Du, Kimberly May, Wei Xu & Hongcheng Liu. (2012) Detection and Quantitation of Afucosylated N-Linked Oligosaccharides in Recombinant Monoclonal Antibodies Using Enzymatic Digestion and LC-MS. Journal of The American Society for Mass Spectrometry 23:7, pages 1241-1249.
Crossref
Siu-Kei Chow & Arturo Casadevall. (2012) Monoclonal Antibodies and Toxins—A Perspective on Function and Isotype. Toxins 4:6, pages 430-454.
Crossref
Kavitha Baruah, Thomas A. Bowden, Benjamin A. Krishna, Raymond A. Dwek, Max Crispin & Christopher N. Scanlan. (2012) Selective Deactivation of Serum IgG: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions. Journal of Molecular Biology 420:1-2, pages 1-7.
Crossref
Kutty Selva Nandakumar. 2012. Antibody‐Mediated Drug Delivery Systems. Antibody‐Mediated Drug Delivery Systems 407 426 .
Sybille Böhm, Inessa Schwab, Anja Lux & Falk Nimmerjahn. (2012) The role of sialic acid as a modulator of the anti-inflammatory activity of IgG. Seminars in Immunopathology 34:3, pages 443-453.
Crossref
Thomas C. Nesspor, T. Shantha Raju, Chen ‐Ni Chin, Omid Vafa & Randall J. Brezski. (2012) Avidity confers FcγR binding and immune effector function to aglycosylated immunoglobulin G1. Journal of Molecular Recognition 25:3, pages 147-154.
Crossref
Claudia Maletzki, Annika Jahnke, Christiane Ostwald, Ernst Klar, Friedrich Prall & Michael Linnebacher. (2012) Ex-vivo Clonally Expanded B Lymphocytes Infiltrating Colorectal Carcinoma Are of Mature Immunophenotype and Produce Functional IgG. PLoS ONE 7:2, pages e32639.
Crossref
A. M. Goetze, Y. D. Liu, T. Arroll, L. Chu & G. C. Flynn. (2011) Rates and impact of human antibody glycation in vivo. Glycobiology 22:2, pages 221-234.
Crossref
Ebru Uçaktürk. (2012) Analysis of glycoforms on the glycosylation site and the glycans in monoclonal antibody biopharmaceuticals. Journal of Separation Science 35:3, pages 341-350.
Crossref
. 2012. Therapeutic Antibody Engineering. Therapeutic Antibody Engineering 405 595 .
. 2012. Therapeutic Antibody Engineering. Therapeutic Antibody Engineering 251 595 .
. 2012. Therapeutic Antibody Engineering. Therapeutic Antibody Engineering 225 595 .
. 2012. Therapeutic Antibody Engineering. Therapeutic Antibody Engineering 197 595 .
. 2012. Therapeutic Antibody Engineering. Therapeutic Antibody Engineering 163 595 .
. 2012. Therapeutic Antibody Engineering. Therapeutic Antibody Engineering 459 595 .
Christiane Jäger, Claudia Ferrara, Pablo Umaña, Anne Zeck, Jörg Thomas Regula & Hans Koll. 2012. Antibody Methods and Protocols. Antibody Methods and Protocols 195 208 .
Thomas Jostock & Hans-Peter Knopf. 2012. Therapeutic Proteins. Therapeutic Proteins 227 238 .
Gary L. Gilliland, Jinquan Luo, Omid Vafa & Juan Carlos Almagro. 2012. Structure-Based Drug Discovery. Structure-Based Drug Discovery 321 349 .
Randall J. Brezski & Juan Carlos Almagro. 2012. Development of Antibody-Based Therapeutics. Development of Antibody-Based Therapeutics 65 93 .
Nigel M. Stapleton, Jan Terje Andersen, Annette M. Stemerding, Stefania P. Bjarnarson, Ruurd C. Verheul, Jacoline Gerritsen, Yixian Zhao, Marion Kleijer, Inger Sandlie, Masja de Haas, Ingileif Jonsdottir, C. Ellen van der Schoot & Gestur Vidarsson. (2011) Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential. Nature Communications 2:1.
Crossref
Xiaoling Wang, Sandeep Kumar & Satish K. Singh. (2011) Disulfide Scrambling in IgG2 Monoclonal Antibodies: Insights from Molecular Dynamics Simulations. Pharmaceutical Research 28:12, pages 3128-3144.
Crossref
Ross Stewart, George Thom, Michaela Levens, Gülin Güler-Gane, Robert Holgate, Pauline M. Rudd, Carl Webster, Lutz Jermutus & John Lund. (2011) A variant human IgG1-Fc mediates improved ADCC. Protein Engineering, Design and Selection 24:9, pages 671-678.
Crossref
Jody D. Berry & Ryan G. Gaudet. (2011) Antibodies in infectious diseases: polyclonals, monoclonals and niche biotechnology. New Biotechnology 28:5, pages 489-501.
Crossref
S. Ha, Y. Ou, J. Vlasak, Y. Li, S. Wang, K. Vo, Y. Du, A. Mach, Y. Fang & N. Zhang. (2011) Isolation and characterization of IgG1 with asymmetrical Fc glycosylation. Glycobiology 21:8, pages 1087-1096.
Crossref
Annette M. Jackson, Donna P. Lucas, J. Keith Melancon & Niraj M. Desai. (2011) Clinical Relevance and IgG Subclass Determination of Non-HLA Antibodies Identified Using Endothelial Cell Precursors Isolated From Donor Blood. Transplantation 92:1, pages 54-60.
Crossref
Bram BlommeChristophe Van SteenkistePaola Grassi, Stuart M. Haslam, Anne Dell, Nico Callewaert & Hans Van Vlierberghe. (2011) Alterations of serum protein N -glycosylation in two mouse models of chronic liver disease are hepatocyte and not B cell driven . American Journal of Physiology-Gastrointestinal and Liver Physiology 300:5, pages G833-G842.
Crossref
Stephan ZeibigZhongmin LiSilvia WagnerHans-Peter HolthoffMartin UngererAndreas BültmannKerstin UhlandJasmin VogelmannThomas SimmetMeinrad GawazGötz Münch. (2011) Effect of the oxLDL Binding Protein Fc-CD68 on Plaque Extension and Vulnerability in Atherosclerosis. Circulation Research 108:6, pages 695-703.
Crossref
Victor S Goldmacher & Yelena V Kovtun. (2011) Antibody–drug conjugates: using monoclonal antibodies for delivery of cytotoxic payloads to cancer cells. Therapeutic Delivery 2:3, pages 397-416.
Crossref
Xu-Rong Jiang, An Song, Svetlana Bergelson, Thomas Arroll, Bhavin Parekh, Kimberly May, Shan Chung, Robert Strouse, Anthony Mire-Sluis & Mark Schenerman. (2011) Advances in the assessment and control of the effector functions of therapeutic antibodies. Nature Reviews Drug Discovery 10:2, pages 101-111.
Crossref
Dongxing Zha, Thomas Linden & Thomas Potgieter. 2011. Antibody Expression and Production. Antibody Expression and Production 77 98 .
Maureen Spearman, Ben Dionne & Michael Butler. 2011. Antibody Expression and Production. Antibody Expression and Production 251 292 .
Sabine Flicker, Elisabeth Gadermaier, Christoph Madritsch & Rudolf Valenta. 2011. Vaccines against Allergies. Vaccines against Allergies 141 159 .
Rasmus Hansen, Alan J. Dickson, Royston Goodacre, Gill M. Stephens & Christopher A. Sellick. (2010) Rapid characterization of N-linked glycans from secreted and gel-purified monoclonal antibodies using MALDI-ToF mass spectrometry. Biotechnology and Bioengineering 107:5, pages 902-908.
Crossref
Sanchayita Ghose, Justin Ladwig & Martin Allen. (2011) Comparison of the chromatographic properties of IgG1 and IgG2 antibody subclasses. Biotechnology and Applied Biochemistry 57:3, pages 111-116.
Crossref
Tony Merry & Sviatlana Astrautsova. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences.
Qian Wang, Nathan A. Lacher, Bilikallahalli K. Muralidhara, Michael R. Schlittler, Serdar Aykent & Charles W. Demarest. (2010) Rapid and refined separation of human IgG2 disulfide isomers using superficially porous particles. Journal of Separation Science 33:17-18, pages 2671-2680.
Crossref
Jonathon P. Leider, Patricia A.R. Brunker & Paul M. Ness. (2010) Convalescent transfusion for pandemic influenza: preparing blood banks for a new plasma product?. Transfusion 50:6, pages 1384-1398.
Crossref
Andrew C. Chan & Paul J. Carter. (2010) Therapeutic antibodies for autoimmunity and inflammation. Nature Reviews Immunology 10:5, pages 301-316.
Crossref
Johannes Stadlmann, Martin Pabst & Friedrich Altmann. (2010) Analytical and Functional Aspects of Antibody Sialylation. Journal of Clinical Immunology 30:S1, pages 15-19.
Crossref

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