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Research Article

Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides

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Pages 1619-1624 | Received 08 Feb 2016, Accepted 26 Feb 2016, Published online: 30 Mar 2016

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Parham Taslimi, Sabiya Osmanova, Cuneyt Caglayan, Fikret Turkan, Sabira Sardarova, Vagif Farzaliyev, Afsun Sujayev, Nastaran Sadeghian & İlhami Gulçin. (2018) Novel amides of 1,1-bis-(carboxymethylthio)-1-arylethanes: Synthesis, characterization, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibitory properties. Journal of Biochemical and Molecular Toxicology 32:9, pages e22191.
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Kadir Aksu, Hülya Akıncıoğlu, Akın Akıncıoğlu, Süleyman Göksu, Ferhan Tümer & İlhami Gülçin. (2018) Synthesis of novel sulfamides incorporating phenethylamines and determination of their inhibition profiles against some metabolic enzymes. Archiv der Pharmazie 351:9, pages 1800150.
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Beyhan Yiğit, Murat Yiğit, Parham Taslimi, Yetkin Gök & İlhami Gülçin. (2018) Schiff bases and their amines: Synthesis and discovery of carbonic anhydrase and acetylcholinesterase enzymes inhibitors. Archiv der Pharmazie 351:9, pages 1800146.
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Silvia Bua, Martina Buonanno, Simona Maria Monti, Manisha Tiwari & Claudiu T. Supuran. (2018) Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal. European Journal of Medicinal Chemistry 156, pages 430-443.
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Halise Inci Gul, Cem Yamali, Merve Bulbuller, Petek Ballar Kirmizibayrak, Mustafa Gul, Andrea Angeli, Silvia Bua & Claudiu T. Supuran. (2018) Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes. Bioorganic Chemistry 78, pages 290-297.
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Umit M. Kocyigit, Parham Taslimi & İlhami Gulçin. (2018) Characterization and inhibition effects of some metal ions on carbonic anhydrase enzyme from Kangal Akkaraman sheep. Journal of Biochemical and Molecular Toxicology 32:8, pages e22172.
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Beyhan Yiğit, Murat Yiğit, Duygu Barut Celepci, Yetkin Gök, Aydın Aktaş, Muhittin Aygün, Parham Taslimi & İlhami Gülçin. (2018) Novel Benzylic Substituted Imidazolinium, Tetrahydropyrimidinium and Tetrahydrodiazepinium Salts: Potent Carbonic Anhydrase and Acetylcholinesterase Inhibitors. ChemistrySelect 3:27, pages 7976-7982.
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Ferhat Türker, Duygu Barut Celepci, Aydın Aktaş, Parham Taslimi, Yetkin Gök, Muhittin Aygün & İlhami Gülçin. (2018) meta -Cyanobenzyl substituted benzimidazolium salts: Synthesis, characterization, crystal structure and carbonic anhydrase, α-glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties . Archiv der Pharmazie 351:7, pages 1800029.
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Parham Taslimi & İlhami Gulçin. (2018) Antioxidant and anticholinergic properties of olivetol. Journal of Food Biochemistry 42:3, pages e12516.
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Cem Yamali, Halise Inci Gul, Abdulilah Ece, Parham Taslimi & Ilhami Gulcin. (2018) Synthesis, molecular modeling, and biological evaluation of 4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1 H -pyrazol-1-yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes . Chemical Biology & Drug Design 91:4, pages 854-866.
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Alessio Nocentini, Davide Moi, Gianfranco Balboni, Severo Salvadori, Valentina Onnis & Claudiu T. Supuran. (2018) Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy. Bioorganic Chemistry 77, pages 633-639.
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Halise Inci Gul, Cem Yamali, Hiroshi Sakagami, Andrea Angeli, Janis Leitans, Andris Kazaks, Kaspars Tars, Dilan Ozmen Ozgun & Claudiu T. Supuran. (2018) New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors. Bioorganic Chemistry 77, pages 411-419.
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Parham Taslimi, Cuneyt Caglayan, Vagif Farzaliyev, Oruj Nabiyev, Afsun Sujayev, Fikret Turkan, Ruya Kaya & İlhami Gulçin. (2018) Synthesis and discovery of potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes inhibitors: The novel N , N ′-bis-cyanomethylamine and alkoxymethylamine derivatives . Journal of Biochemical and Molecular Toxicology 32:4, pages e22042.
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Fatoş Erdemir, Duygu Barut Celepci, Aydın Aktaş, Parham Taslimi, Yetkin Gök, Hasan Karabıyık & İlhami Gülçin. (2018) 2-Hydroxyethyl substituted NHC precursors: Synthesis, characterization, crystal structure and carbonic anhydrase, α-glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties. Journal of Molecular Structure 1155, pages 797-806.
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Fikret Türkan, Zübeyir Huyut, Parham Taslimi & İlhami Gülçin. (2018) The in vivo effects of cefazolin, cefuroxime, and cefoperazon on the carbonic anhydrase in different rat tissues . Journal of Biochemical and Molecular Toxicology 32:3, pages e22041.
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Parham Taslimi, Afsun Sujayev, Fikret Turkan, Emin Garibov, Zübeyir Huyut, Vagif Farzaliyev, Sevgi Mamedova & İlhami Gulçin. (2018) Synthesis and investigation of the conversion reactions of pyrimidine-thiones with nucleophilic reagent and evaluation of their acetylcholinesterase, carbonic anhydrase inhibition, and antioxidant activities. Journal of Biochemical and Molecular Toxicology 32:2, pages e22019.
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Yakup Sarı, Aydın Aktaş, Parham Taslimi, Yetkin Gök & İlhami Gulçin. (2018) Novel N -propylphthalimide- and 4-vinylbenzyl-substituted benzimidazole salts: Synthesis, characterization, and determination of their metal chelating effects and inhibition profiles against acetylcholinesterase and carbonic anhydrase enzymes . Journal of Biochemical and Molecular Toxicology 32:1, pages e22009.
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Nilufer Bulut, Umit M. Kocyigit, Ibrahim H. Gecibesler, Taner Dastan, Huseyin Karci, Parham Taslimi, Sevgi Durna Dastan, Ilhami Gulcin & Ahmet Cetin. (2018) Synthesis of some novel pyridine compounds containing bis-1,2,4-triazole/thiosemicarbazide moiety and investigation of their antioxidant properties, carbonic anhydrase, and acetylcholinesterase enzymes inhibition profiles. Journal of Biochemical and Molecular Toxicology 32:1, pages e22006.
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Ümit M. Koçyiğit, Sevgi Durna Daştan, Parham Taslimi, Taner Daştan & İlhami Gülçin. (2018) Inhibitory effects of some drugs on carbonic anhydrase enzyme purified from Kangal Akkaraman sheep in Sivas, Turkey. Journal of Biochemical and Molecular Toxicology 32:1, pages e22000.
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Parham Taslimi, Cuneyt Caglayan & İlhami Gulcin. (2017) The impact of some natural phenolic compounds on carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes: An antidiabetic, anticholinergic, and antiepileptic study. Journal of Biochemical and Molecular Toxicology 31:12, pages e21995.
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Umit M. Kocyigit, Yakup Budak, Fikret Eligüzel, Parham Taslimi, Deryanur Kılıç, İlhami Gulçin & Mustafa Ceylan. (2017) Synthesis and Carbonic Anhydrase Inhibition of Tetrabromo Chalcone Derivatives. Archiv der Pharmazie 350:12, pages 1700198.
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Parham Taslimi, Hülya Akıncıoglu & İlhami Gülçin. (2017) Synephrine and phenylephrine act as α‐amylase, α‐glycosidase, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase enzymes inhibitors. Journal of Biochemical and Molecular Toxicology 31:11.
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Taner Dastan, Umit M. Kocyigit, Sevgi Durna Dastan, Pakize Canturk Kilickaya, Parham Taslimi, Ozge Cevik, Metin Koparir, Cahit Orek, İlhami Gulçin & Ahmet Cetin. (2017) Investigation of acetylcholinesterase and mammalian DNA topoisomerases, carbonic anhydrase inhibition profiles, and cytotoxic activity of novel bis(α‐aminoalkyl)phosphinic acid derivatives against human breast cancer. Journal of Biochemical and Molecular Toxicology 31:11.
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Akın Akıncıoğlu, Ebutalib Kocaman, Hülya Akıncıoğlu, Ramin Ekhteiari Salmas, Serdar Durdagi, İlhami Gülçin, Claudiu T. Supuran & Süleyman Göksu. (2017) The synthesis of novel sulfamides derived from β-benzylphenethylamines as acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase enzymes inhibitors. Bioorganic Chemistry 74, pages 238-250.
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Ümit M. KOÇYİĞİT. (2017) The Effects of Oxytocin and Oxytocin Receptor Antagonist Atosiban on the Carbonic Anhydrase and Acetylcholinesterase Enzymes from Lung Tissues of Rats. Cumhuriyet Science Journal 38:3, pages 450-460.
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Cem Yamali, Dilan Ozmen Ozgun, Halise Inci Gul, Hiroshi Sakagami, Cavit Kazaz & Noriyuki Okudaira. (2017) Synthesis and structure elucidation of 1-(2,5/3,5-difluorophenyl)-3-(2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents. Medicinal Chemistry Research 26:9, pages 2015-2023.
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Umit M. Kocyigit, Parham Taslimi, Hayreddin Gezegen, İlhami Gulçin & Mustafa Ceylan. (2017) Evaluation of acetylcholinesterase and carbonic anhydrase inhibition profiles of 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes. Journal of Biochemical and Molecular Toxicology 31:9, pages e21938.
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Parham Taslimi, Sabiya Osmanova, İlhami Gulçin, Sabira Sardarova, Vagif Farzaliyev, Afsun Sujayev, Ruya Kaya, Fatma Koc, Sukru Beydemir, Saleh H. Alwasel & Omer Irfan Kufrevioglu. (2017) Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base. Journal of Biochemical and Molecular Toxicology 31:9, pages e21931.
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Parham Taslimi, Afsun Sujayev, Emin Garibov, Nazar Nazarov, Zubeyir Huyut, Saleh H. Alwasel & İlhami Gulçin. (2017) Synthesis of new cyclic thioureas and evaluation of their metal-chelating activity, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibition profiles. Journal of Biochemical and Molecular Toxicology 31:7, pages e21897.
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Simona Maria Monti, Martina Buonanno, Manisha Tiwari & Claudiu T. Supuran. (2017) Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. Journal of Medicinal Chemistry 60:6, pages 2456-2469.
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Umit M. Kocyigit, Yakup Budak, Meliha Burcu Gürdere, Şaban Tekin, Tuğba Kul Köprülü, Fatih Ertürk, Kezban Özcan, İlhami Gülçin & Mustafa Ceylan. (2017) Synthesis, characterization, anticancer, antimicrobial and carbonic anhydrase inhibition profiles of novel (3a R ,4 S ,7 R ,7a S )-2-(4-(( E )-3-(3-aryl)acryloyl) phenyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione derivatives. Bioorganic Chemistry 70, pages 118-125.
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