Citations (30)
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Lennart Kühl, Nadine Aschmoneit, Roland E. Kontermann & Oliver Seifert. (2022) The eIg technology to generate Ig-like bispecific antibodies. mAbs 14:1.
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Jingjing Zhang, Han Zhang & Litao Sun. (2022) Therapeutic antibodies for COVID-19: is a new age of IgM, IgA and bispecific antibodies coming?. mAbs 14:1.
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Dennis J. Underwood, Jeffrey Bettencourt & Zahra Jawad. (2022) The manufacturing considerations of bispecific antibodies. Expert Opinion on Biological Therapy 22:8, pages 1043-1065.
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Lukas Pekar, Michael Busch, Bernhard Valldorf, Steffen C. Hinz, Lars Toleikis, Simon Krah & Stefan Zielonka. (2020) Biophysical and biochemical characterization of a VHH-based IgG-like bi- and trispecific antibody platform. mAbs 12:1.
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Robert J. Benschop, Chi-Kin Chow, Yu Tian, James Nelson, Barbra Barmettler, Shane Atwell, David Clawson, Qing Chai, Bryan Jones, Jon Fitchett, Stacy Torgerson, Yan Ji, Holly Bina, Ningjie Hu, Mahmoud Ghanem, Joseph Manetta, Victor J. Wroblewski, Jirong Lu & Barrett W. Allan. (2019) Development of tibulizumab, a tetravalent bispecific antibody targeting BAFF and IL-17A for the treatment of autoimmune disease. mAbs 11:6, pages 1175-1190.
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Oliver Seifert, Alexander Rau, Nadine Beha, Fabian Richter & Roland E. Kontermann. (2019) Diabody-Ig: a novel platform for the generation of multivalent and multispecific antibody molecules. mAbs 11:5, pages 919-929.
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Chris Spahr, Kannan Gunasekaran, Kenneth W. Walker & Stone D.-H. Shi. (2017) High-resolution mass spectrometry confirms the presence of a hydroxyproline (Hyp) post-translational modification in the GGGGP linker of an Fc-fusion protein. mAbs 9:5, pages 812-819.
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Ulrich Brinkmann & Roland E. Kontermann. (2017) The making of bispecific antibodies. mAbs 9:2, pages 182-212.
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Anke Steinmetz, François Vallée, Christian Beil, Christian Lange, Nicolas Baurin, Jochen Beninga, Cécile Capdevila, Carsten Corvey, Alain Dupuy, Paul Ferrari, Alexey Rak, Peter Wonerow, Jochen Kruip, Vincent Mikol & Ercole Rao. (2016) CODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications. mAbs 8:5, pages 867-878.
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Ingo Schubert, Domenica Saul, Stefanie Nowecki, Andreas Mackensen, Georg H Fey & Fuat S Oduncu. (2014) A dual-targeting triplebody mediates preferential redirected lysis of antigen double-positive over single-positive leukemic cells. mAbs 6:1, pages 286-296.
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Clarissa G. Jakob, Rohinton Edalji, Russell A. Judge, Enrico DiGiammarino, Yingchun Li, Jijie Gu & Tariq Ghayur. (2013) Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig™) molecule. mAbs 5:3, pages 358-363.
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Christian Klein, Claudio Sustmann, Markus Thomas, Kay Stubenrauch, Rebecca Croasdale, Jürgen Schanzer, Ulrich Brinkmann, Hubert Kettenberger, Jörg T. Regula & Wolfgang Schaefer. (2012) Progress in overcoming the chain association issue in bispecific heterodimeric IgG antibodies. mAbs 4:6, pages 653-663.
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Gregory L. Moore, Cristina Bautista, Erik Pong, Duc-Hanh T. Nguyen, Jonathan Jacinto, Araz Eivazi, Umesh S. Muchhal, Sher Karki, Seung Y. Chu & Greg A. Lazar. (2011) A novel bispecific antibody format enables simultaneous bivalent and monovalent co-engagement of distinct target antigens. mAbs 3:6, pages 546-557.
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Articles from other publishers (17)
Johanna Voigt, Christoph Meyer & Frank Bordusa. (2022) Synthesis of Multiple Bispecific Antibody Formats with Only One Single Enzyme Based on Enhanced Trypsiligase. International Journal of Molecular Sciences 23:6, pages 3144.
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Daniel Klewinghaus, Lukas Pekar, Paul Arras, Simon Krah, Bernhard Valldorf, Harald Kolmar & Stefan Zielonka. (2022) Grabbing the Bull by Both Horns: Bovine Ultralong CDR-H3 Paratopes Enable Engineering of ‘Almost Natural’ Common Light Chain Bispecific Antibodies Suitable For Effector Cell Redirection. Frontiers in Immunology 12.
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Lin Yu, Nan Huang, Liangpeng Ge, Heng Sun, Yuna Fu, Chundong Liu & Jianhua Wang. (2021) Structural design of tetravalent T-cell engaging bispecific antibodies: improve developability by engineering disulfide bonds. Journal of Biological Engineering 15:1.
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Mehdi Mohammadi, Mahmood Jeddi-Tehrani, Forough Golsaz-Shirazi, Mohammad Arjmand, Tannaz Bahadori, Mohammad Ali Judaki, Fariba Shiravi, Hengameh Ahmadi Zare, Farzaneh Notash Haghighat, Maryam Mobini, Mohammad Mehdi Amiri & Fazel Shokri. (2021) A Novel Anti-HER2 Bispecific Antibody With Potent Tumor Inhibitory Effects In Vitro and In Vivo. Frontiers in Immunology 11.
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Tuan-Minh Do, Cécile Capdevila, Laurent Pradier, Véronique Blanchard, Mati Lopez-Grancha, Nathalie Schussler, Anke Steinmetz, Jochen Beninga, Denis Boulay, Philippe Dugay, Patrick Verdier, Nadine Aubin, Gihad Dargazanli, Catarina Chaves, Elisabeth Genet, Yves Lossouarn, Christophe Loux, François Michoux, Nicolas Moindrot, Franck Chanut, Thierry Gury, Stéphanie Eyquem, Delphine Valente, Olivier Bergis, Ercole Rao & Dominique Lesuisse. (2020) Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model. Molecular Therapy - Methods & Clinical Development 19, pages 58-77.
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Tim Hofmann, Simon Krah, Carolin Sellmann, Stefan Zielonka & Achim Doerner. (2020) Greatest Hits—Innovative Technologies for High Throughput Identification of Bispecific Antibodies. International Journal of Molecular Sciences 21:18, pages 6551.
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Hyunbo Shim. (2020) Bispecific Antibodies and Antibody–Drug Conjugates for Cancer Therapy: Technological Considerations. Biomolecules 10:3, pages 360.
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Siwei Nie, Zhuozhi Wang, Maria Moscoso-Castro, Paul D'Souza, Can Lei, Jianqing Xu & Jijie Gu. (2020) Biology drives the discovery of bispecific antibodies as innovative therapeutics. Antibody Therapeutics 3:1, pages 18-62.
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Feng Dong & Tariq Ghayur. (2019) Recent advancements in DVD-Ig based therapeutic development. Drug Discovery Today: Technologies 34, pages 1-7.
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Xiufeng Wu & Stephen J. Demarest. (2019) Building blocks for bispecific and trispecific antibodies. Methods 154, pages 3-9.
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Xiufeng Wu, Richard Yuan, Michael Bacica & Stephen J Demarest. (2018) Generation of orthogonal Fab-based trispecific antibody formats. Protein Engineering, Design and Selection 31:7-8, pages 249-256.
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E. A. Vasilenko, V. V. Mokhonov, E. N. Gorshkova & I. V. Astrakhantseva. (2018) Bispecific Antibodies: Formats and Areas of Application. Molecular Biology 52:3, pages 323-334.
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Jianlong Lou, Weihua Wen, Fraser Conrad, Qi Meng, Jianbo Dong, Zhengda Sun, Consuelo Garcia-Rodriguez, Shauna Farr-Jones, Luisa Cheng, Thomas Henderson, Jennifer Brown, Theresa Smith, Leonard Smith, Anthony Cormier & James Marks. (2018) A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A. Toxins 10:2, pages 84.
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Nicole A. Belmar, Sarah W. Chan, Melvin I. Fox, Josue A. Samayoa, Marcia M. Stickler, Ninian N. Tran, Yoshiko Akamatsu, Diane Hollenbaugh, Fiona A. Harding & Hamsell M. Alvarez. (2017) Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice. The Journal of Immunology 198:11, pages 4502-4512.
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Shimobi C. Onuoha, Mathieu Ferrari, Daniele Sblattero & Costantino Pitzalis. (2015) Rational Design of Antirheumatic Prodrugs Specific for Sites of Inflammation. Arthritis & Rheumatology 67:10, pages 2661-2672.
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Alexey A. Lugovskoy & Melissa L. Geddie. 2015. Biobetters. Biobetters
203
220
.
Juergen M. Schanzer, Katharina Wartha, Rebecca Croasdale, Samuel Moser, Klaus-Peter Künkele, Carola Ries, Werner Scheuer, Harald Duerr, Sandra Pompiati, Jan Pollman, Jan Stracke, Wilma Lau, Stefan Ries, Ulrich Brinkmann, Christian Klein & Pablo Umana. (2014) A Novel Glycoengineered Bispecific Antibody Format for Targeted Inhibition of Epidermal Growth Factor Receptor (EGFR) and Insulin-like Growth Factor Receptor Type I (IGF-1R) Demonstrating Unique Molecular Properties. Journal of Biological Chemistry 289:27, pages 18693-18706.
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