Current Medical Research and Opinion, Volume 38, Issue 2 (2022)

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Current Medical Research and Opinion, Volume 38, Issue 2 (2022)

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RARE DISEASES: Interviews

An interview on rare diseases and orphan medicines with Dr Daniel O’Connor, medical assessor at the Medicines and Healthcare products Regulatory Agency (MHRA), UK
Daniel O’Connor
Pages: 159-160
Published online: 19 Jan 2022
CitationforAn interview on rare diseases and orphan medicines with Dr Daniel O’Connor, medical assessor at the Medicines and Healthcare products Regulatory Agency (MHRA), UK | Full Text | PDF (268 KB) | EPUB
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An interview on rare and genetic diseases with Dr Bruce Korf, Associate Dean for Genomic Medicine at the University of Alabama at Birmingham
Bruce Korf
Pages: 161-163
Published online: 20 Jan 2022
First Page PreviewforAn interview on rare and genetic diseases with Dr Bruce Korf, Associate Dean for Genomic Medicine at the University of Alabama at Birmingham | Full Text | PDF (369.3 KB) | EPUB
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PATIENT OUTCOMES: Original Article

Article
Real-world impact of disease on functioning and activity: what is missed when using general instruments to estimate quality-adjusted life years
Tingjian Yan, Jesse D. Ortendahl, Eunice Chang, Zac Wessler, Amanda L. Harmon & Michael S. Broder
Pages: 165-170
Published online: 01 Dec 2021
AbstractforReal-world impact of disease on functioning and activity: what is missed when using general instruments to estimate quality-adjusted life years | Full Text | References | PDF (1 MB) | EPUB
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PATIENT CARE: Original Articles

Article
The SPUR adherence profiling tool: preliminary results of algorithm development
Elodie de Bock, Kevin Dolgin, Benoit Arnould, Guillaume Hubert, Aaron Lee & John D. Piette
Pages: 171-179
Published online: 11 Dec 2021
AbstractforThe SPUR adherence profiling tool: preliminary results of algorithm development | Full Text | References | PDF (1.4 MB) | EPUB
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Open Access
Article
Impact of the iCODEX tool in routine clinical practice in Spain
María Gómez-Antúnez, Jesús Recio-Iglesias, Pere Almagro, Jesús Díez-Manglano, Francisco López-García & Ramon Boixeda
Pages: 181-187
Published online: 24 Dec 2021
AbstractforImpact of the iCODEX tool in routine clinical practice in Spain | Full Text | References | PDF (849.9 KB) | EPUB
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PUBLISHING: Original Article

Article
Plain language summaries of publications of company-sponsored medical research: what key questions do we need to address?
Dawn Lobban, Jason Gardner, Robert Matheis & on behalf of the ISMPP PLS Perspectives Working Group
Pages: 189-200
Published online: 04 Nov 2021
AbstractforPlain language summaries of publications of company-sponsored medical research: what key questions do we need to address? | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
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DISEASE DIAGNOSIS: Original Article

Article
Systems biomarker characteristics of circulating alkaline phosphatase activities for 48 types of human diseases
Wenhao Su, Tong Qiu, Meng Zhang, Cui Hao, Pengjiao Zeng, Zhangfeng Huang, Wenxing Du, Tianxiang Yun, Yunpeng Xuan, Lijuan Zhang, Yachong Guo & Wenjie Jiao
Pages: 201-209
Published online: 12 Nov 2021
AbstractforSystems biomarker characteristics of circulating alkaline phosphatase activities for 48 types of human diseases | Full Text | References | PDF (2 MB) | EPUB
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PHARMACOLOGY: Review Article

Review Article
What do we really know about the safety and efficacy of melatonin for sleep disorders?
David J. Kennaway
Pages: 211-227
Published online: 24 Nov 2021
AbstractforWhat do we really know about the safety and efficacy of melatonin for sleep disorders? | Full Text | References | PDF (2 MB) | EPUB
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PHARMACOLOGY: Original Article

Article
Prediction and associated factors of hypothyroidism in systemic lupus erythematosus: a cross-sectional study based on multiple machine learning algorithms
Ting Huang, Siyang Liu, Jian Huang, Jiarong Li, Guixiong Liu, Weiru Zhang & Xuan Wang
Pages: 229-235
Published online: 21 Dec 2021
AbstractforPrediction and associated factors of hypothyroidism in systemic lupus erythematosus: a cross-sectional study based on multiple machine learning algorithms | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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PAIN MEDICINE: Original Article

Article
COMET – effectiveness and tolerability of methocarbamol versus oral opioid-analgesics as add-on measure in patients with non-specific low back pain refractory to recommended 1st line treatments. A retrospective analysis of depersonalized propensity score matched open-label real-world 4-week data from the German Pain e-Registry
Michael A. Ueberall & Gerhard Mueller-Schwefe
Pages: 237-253
Published online: 14 Dec 2021
AbstractforCOMET – effectiveness and tolerability of methocarbamol versus oral opioid-analgesics as add-on measure in patients with non-specific low back pain refractory to recommended 1st line treatments. A retrospective analysis of depersonalized propensity score matched open-label real-world 4-week data from the German Pain e-Registry | Full Text | References | PDF (2.5 MB) | EPUB
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NEUROLOGY: Original Article

Article
Intradiscal vacuum phenomenon and spinal degeneration: a cross-sectional analysis of 219 subjects
Murat Şakir Ekşi, Emel Ece Özcan-Ekşi, Alper Akkaş, Ömer Orhun, Havva Nur Arslan, Maftun Zarbizada, Doğu Küçüksüleymanoğlu, M. Necmettin Pamir & Edward C. Benzel
Pages: 255-263
Published online: 25 Oct 2021
AbstractforIntradiscal vacuum phenomenon and spinal degeneration: a cross-sectional analysis of 219 subjects | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
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INFECTIOUS DISEASES: Brief Report

Brief Report
A 10-year economic analysis of HIV management in Greece: evidence of efficient resource allocation
Kostas Athanasakis, Vasiliki Naoum, Panagiota Naoum, Nikos Nomikos, Dorina Theodoratou & John Kyriopoulos
Pages: 265-271
Published online: 23 Dec 2021
AbstractforA 10-year economic analysis of HIV management in Greece: evidence of efficient resource allocation | Full Text | References | PDF (952 KB) | EPUB
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INFECTIOUS DISEASES: Original Articles

Article
Missing diagnoses of congenital cytomegalovirus infection in electronic health records for infants with laboratory-confirmed infection
Alexandra Campione, Tatiana M. Lanzieri, Emily Ricotta, Scott D. Grosse, Sameer S. Kadri, Veronique Nussenblatt & D. Rebecca Prevots
Pages: 273-275
Published online: 06 Dec 2021
AbstractforMissing diagnoses of congenital cytomegalovirus infection in electronic health records for infants with laboratory-confirmed infection | Full Text | References | PDF (624.9 KB) | EPUB
  • 1497 Views
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Free Access
Article
Comorbid diseases and conditions in people with HIV in the UK
Bethan I. Jones, Andrew Freedman, Melissa J. Thomas, Celia Villalba-Mendez, Leena Sathia, Deborah Flanagan, Scott Francis & Craig J. Currie
Pages: 277-285
Published online: 30 Nov 2021
AbstractforComorbid diseases and conditions in people with HIV in the UK | Full Text | References | PDF (985.6 KB) | EPUB
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Article
Body mass index increase and weight gain among people living with HIV-1 initiated on single-tablet darunavir/cobicistat/emtricitabine/tenofovir alafenamide or bictegravir/emtricitabine/tenofovir alafenamide in the United States
Bruno Emond, Carmine Rossi, Aurélie Côté-Sergent, Brahim Bookhart, David Anderson, Patrick Lefebvre, Marie-Hélène Lafeuille & Prina Donga
Pages: 287-298
Published online: 07 Dec 2021
AbstractforBody mass index increase and weight gain among people living with HIV-1 initiated on single-tablet darunavir/cobicistat/emtricitabine/tenofovir alafenamide or bictegravir/emtricitabine/tenofovir alafenamide in the United States | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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INFECTIOUS DISEASES: Commentary

Article Commentary
Cerebral mucormycosis: intranasal route to deliver amphotericin B for effective management?
Ruqaiyyah Siddiqui, Mohamed Yehia Abouleish, Mustafa Khamis, Taleb Ibrahim & Naveed Ahmed Khan
Pages: 299-301
Published online: 12 Nov 2021
AbstractforCerebral mucormycosis: intranasal route to deliver amphotericin B for effective management? | Full Text | References | PDF (617.9 KB) | EPUB
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HEMATOLOGY: Original Article

Article
Relationship between baseline clinical characteristics and efficacy of lusutrombopag in thrombocytopenic patients with chronic liver disease: post hoc analysis of two placebo-controlled phase 3 trials
Katsuaki Tanaka, Takamichi Baba, Manami Yoshida, Motofumi Iguchi, Takuhiro Sonoyama, Takahiro Fukuhara & Takeshi Kano
Pages: 303-310
Published online: 22 Dec 2021
AbstractforRelationship between baseline clinical characteristics and efficacy of lusutrombopag in thrombocytopenic patients with chronic liver disease: post hoc analysis of two placebo-controlled phase 3 trials | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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COVID-19: Original Article

Article
The impact of COVID-19 on chronic therapies: the Pescara (ASL) local health authority experience in Italy
Alessia Romagnoli, Fiorenzo Santoleri & Alberto Costantini
Pages: 311-316
Published online: 10 Dec 2021
AbstractforThe impact of COVID-19 on chronic therapies: the Pescara (ASL) local health authority experience in Italy | Full Text | References | PDF (652 KB) | EPUB
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COVID-19: Review Article

Review Article
Conducting and critically appraising a high-quality systematic review and Meta-analysis pertaining to COVID-19
Niraj Nirmal Pandey & Sanjiv Sharma
Pages: 317-325
Published online: 14 Dec 2021
AbstractforConducting and critically appraising a high-quality systematic review and Meta-analysis pertaining to COVID-19 | Full Text | References | PDF (1.3 MB) | EPUB
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COVID-19: Original Article

Article
Knowledge, attitude and practice towards COVID-19 and perceived challenges of working during the movement control order: a quantitative analysis among healthcare workers in a Malaysian northwestern state
Amalina Anuar, Wei Chern Ang, Nailul Muna Ahmad Musadad, Siti Noriani Abdol Wahab, Noorhafini Abdul Sukur & Othman Warijo
Pages: 327-338
Published online: 12 Nov 2021
AbstractforKnowledge, attitude and practice towards COVID-19 and perceived challenges of working during the movement control order: a quantitative analysis among healthcare workers in a Malaysian northwestern state | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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