Expert Opinion on Drug Discovery, Volume 10, Issue 5 (2015)

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Expert Opinion on Drug Discovery, Volume 10, Issue 5 (2015)

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Editorial

Editorial
Activity cliff clusters as a source of structure–activity relationship information
Dilyana Dimova, Dagmar Stumpfe, Ye Hu & Jürgen Bajorath
Pages: 441-447
Published online: 25 Feb 2015
AbstractforActivity cliff clusters as a source of structure–activity relationship information | Full Text | References | PDF (607.1 KB)
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Free Access

Review

The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
Samuel Genheden & Ulf Ryde
Pages: 449-461
Published online: 02 Apr 2015
AbstractforThe MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities | Full Text | References | PDF (567.1 KB)
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Open Access
Emerging formats for next-generation antibody drug conjugates
Mahendra P Deonarain, Gokhan Yahioglu, Ioanna Stamati & Jared Marklew
Pages: 463-481
Published online: 23 Mar 2015
AbstractforEmerging formats for next-generation antibody drug conjugates | Full Text | References | PDF (4 MB)
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Targeted approaches to childhood cancer: progress in drug discovery and development
Steffen Hirsch, Lynley V Marshall, Fernando Carceller Lechon, Andrew DJ Pearson & Lucas Moreno
Pages: 483-495
Published online: 03 Apr 2015
AbstractforTargeted approaches to childhood cancer: progress in drug discovery and development | Full Text | References | PDF (273.6 KB)
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Animal models for acute radiation syndrome drug discovery
Vijay K Singh PhD, Victoria L Newman, Allison N Berg & Thomas J MacVittie
Pages: 497-517
Published online: 27 Mar 2015
AbstractforAnimal models for acute radiation syndrome drug discovery | Full Text | References | PDF (1.3 MB)
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Open Access
The application of engineered liver tissues for novel drug discovery
Christine Lin, Kimberly R Ballinger & Salman R Khetani PhD
Pages: 519-540
Published online: 03 Apr 2015
AbstractforThe application of engineered liver tissues for novel drug discovery | Full Text | References | PDF (983.6 KB)
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Designing drugs that combat kidney damage
Adrián M Ramos PhD, Cristian González-Guerrero BsC, Ana Sanz PhD, María Dolores Sanchez-Niño PhD, Laura Rodríguez-Osorio MD, Catalina Martín-Cleary MD, Beatriz Fernández-Fernández MD, Marta Ruiz-Ortega PhD & Alberto Ortiz (Professor) MD PhD
Pages: 541-556
Published online: 03 Apr 2015
AbstractforDesigning drugs that combat kidney damage | Full Text | References | PDF (500.8 KB)
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Positron-emission tomography molecular imaging of glia and myelin in drug discovery for multiple sclerosis
Paul M Matthews (Professor) & Gourab Datta
Pages: 557-570
Published online: 05 Apr 2015
AbstractforPositron-emission tomography molecular imaging of glia and myelin in drug discovery for multiple sclerosis | Full Text | References | PDF (594.6 KB)
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Further Readings

Related articles
Page: 1
Published online: 21 Apr 2015
CitationforRelated articles | Full Text | PDF (86.3 KB)
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