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Volume 1, Issue 5

Future Medicinal Chemistry

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Future Medicinal Chemistry, Volume 1, Issue 5 (2009)

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Future Medicinal Chemistry, Volume 1, Issue 5 (2009)

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Vol 16, 2024 Vol 15, 2023 Vol 14, 2022 Vol 13, 2021 Vol 12, 2020 Vol 11, 2019 Vol 10, 2018 Vol 9, 2017 Vol 8, 2016 Vol 7, 2015 Vol 6, 2014 Vol 5, 2013 Vol 4, 2012 Vol 3, 2011 Vol 2, 2010 Volume 1, 2009

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Foreword

Introduction

Welcome to ‘Fluorine in Medicinal Chemistry’

P Veeraraghavan Ramachandran

Pages: 771-772

Published online: 19 Aug 2009

CitationforWelcome to ‘Fluorine in Medicinal Chemistry’ | Full Text | References | PDF (503.6 KB)

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Free Access

News & Analysis

News

News & Analysis

Pages: 773-775

Published online: 19 Aug 2009

First Page PreviewforNews & Analysis | Full Text | PDF (636.9 KB)

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Perspective

Article

Fluorine in Medicinal Chemistry: A Century of Progress and a 60-Year Retrospective of Selected Highlights

Robert Filler & Rituparna Saha

Pages: 777-791

Published online: 19 Aug 2009

AbstractforFluorine in Medicinal Chemistry: A Century of Progress and a 60-Year Retrospective of Selected Highlights | Full Text | References | PDF (991.5 KB)

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Review

Article

Practical Synthesis of Fluorine-Containing α- and β-Amino Acids: Recipes from Kiev, Ukraine

Valery P Kukhar, Alexander E Sorochinsky & Vadim A Soloshonok

Pages: 793-819

Published online: 19 Aug 2009

AbstractforPractical Synthesis of Fluorine-Containing α- and β-Amino Acids: Recipes from Kiev, Ukraine | Full Text | References | PDF (1.8 MB)

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Article

Fluorinated Molecules in the Diagnosis and Treatment of Neurodegenerative Diseases

Boyenoh Gaye & Adeboye Adejare

Pages: 821-833

Published online: 19 Aug 2009

AbstractforFluorinated Molecules in the Diagnosis and Treatment of Neurodegenerative Diseases | Full Text | References | PDF (1.3 MB)

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Article

Possible Origin of Modified Eag Activity by Point-Fluorination of Insect Pheromones

Shuichi Hayase, Michel Renou & Toshiyuki Itoh

Pages: 835-845

Published online: 19 Aug 2009

AbstractforPossible Origin of Modified Eag Activity by Point-Fluorination of Insect Pheromones | Full Text | References | PDF (2.3 MB)

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Article

Developments in Fluorocyclization Methodologies

Susan C Wilkinson, Roger Salmon & Véronique Gouverneur

Pages: 847-863

Published online: 19 Aug 2009

AbstractforDevelopments in Fluorocyclization Methodologies | Full Text | References | PDF (1.3 MB)

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Article

Fluorinase: A Tool for the Synthesis of ¹⁸F-Labeled Sugars and Nucleosides for Pet

Mayca Onega, Margit Winkler & David O‘Hagan

Pages: 865-873

Published online: 19 Aug 2009

AbstractforFluorinase: A Tool for the Synthesis of ¹⁸F-Labeled Sugars and Nucleosides for Pet | Full Text | References | PDF (767.5 KB)

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Article

Synthesis of Fluorinated Chiral Amines Using N-Tert-Butylsulfinyl Imines

Jun Liu & Jinbo Hu

Pages: 875-888

Published online: 19 Aug 2009

AbstractforSynthesis of Fluorinated Chiral Amines Using N-Tert-Butylsulfinyl Imines | Full Text | References | PDF (1.5 MB)

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Special Report

Article

Fluorous-Based Small-Molecule Microarrays for Protein, Antibody and Enzyme Screening

Eun-Ho Song & Nicola L B Pohl

Pages: 889-896

Published online: 19 Aug 2009

AbstractforFluorous-Based Small-Molecule Microarrays for Protein, Antibody and Enzyme Screening | Full Text | References | PDF (890 KB)

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Research Article

Article

Concise Asymmetric Synthesis of Configurationally Stable 4-Trifluoromethyl Thalidomide

Vadim A Soloshonok, Takeshi Yamada, Kazuhiko Sakaguchi & Yasufumi Ohfune

Pages: 897-908

Published online: 19 Aug 2009

AbstractforConcise Asymmetric Synthesis of Configurationally Stable 4-Trifluoromethyl Thalidomide | Full Text | References | PDF (951.8 KB)

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Article

Gallium (III) Triflate-Catalyzed Synthesis of Heterocycles: Quinoxalines, 1,5-Benzodiazepines and Their Fluorinated Derivatives

G K Surya Prakash, Habiba Vaghoo, Arthi Venkat, Chiradeep Panja, Sujith Chacko, Thomas Mathew & George A Olah

Pages: 909-920

Published online: 19 Aug 2009

AbstractforGallium (III) Triflate-Catalyzed Synthesis of Heterocycles: Quinoxalines, 1,5-Benzodiazepines and Their Fluorinated Derivatives | Full Text | References | PDF (2.1 MB)

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Article

New Preparation and Synthetic Reactions of 3,3,3-Trifluoropropynyllithium, -Borate and -Stannane: Facile Synthesis of Trifluoromethylated Allenes, Arylacetylenes and Enynes

Masaki Shimizu, Masahiro Higashi, Youhei Takeda, Masahito Murai, Guofang Jiang, Yuiga Asai, Yoshiaki Nakao, Eiji Shirakawa & Tamejiro Hiyama

Pages: 921-945

Published online: 19 Aug 2009

AbstractforNew Preparation and Synthetic Reactions of 3,3,3-Trifluoropropynyllithium, -Borate and -Stannane: Facile Synthesis of Trifluoromethylated Allenes, Arylacetylenes and Enynes | Full Text | References | PDF (2 MB)

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Article

Methylsulfonylpyrazolyl Oxadiazoles and Thiadiazoles as Potent, Orally Bioavailable Cannabinoid-1 Receptor Antagonists for the Treatment of Obesity

Hee Jeong Seo, Min Ju Kim, Kwang-Seop Song, Sung-Han Lee, Myung Eun Jung, Mi-Soon Kim, Hyun-Ju Park, Jakyung Yoo, Chong-Hwan Chang, Jeongmin Kim & Jinhwa Lee

Pages: 947-967

Published online: 19 Aug 2009

AbstractforMethylsulfonylpyrazolyl Oxadiazoles and Thiadiazoles as Potent, Orally Bioavailable Cannabinoid-1 Receptor Antagonists for the Treatment of Obesity | Full Text | References | PDF (3.8 MB)

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Article

Fluorinated Isatin Derivatives. Part 3. New Side-Chain Fluoro-Functionalized Pyrrolidinyl Sulfonyl Isatins as Potent Caspase-3 and -7 Inhibitors

Anil Kumar Podichetty, Stefan Wagner, Andreas Faust, Michael Schäfers, Otmar Schober, Klaus Kopka & Günter Haufe

Pages: 969-989

Published online: 19 Aug 2009

AbstractforFluorinated Isatin Derivatives. Part 3. New Side-Chain Fluoro-Functionalized Pyrrolidinyl Sulfonyl Isatins as Potent Caspase-3 and -7 Inhibitors | Full Text | References | PDF (1.6 MB)

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Preliminary Communication

Brief Report

Difluoromethylenated Polyhydroxylated Pyrrolidines: Facile Synthesis, Crystal Structure and Biological Evaluation

Ruo-Wen Wang, Jun Xu, Oscar Lopez, Mikael Bols & Feng-Ling Qing

Pages: 991-997

Published online: 19 Aug 2009

AbstractforDifluoromethylenated Polyhydroxylated Pyrrolidines: Facile Synthesis, Crystal Structure and Biological Evaluation | Full Text | References | PDF (761.7 KB)

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Future Medicinal Chemistry (Vol.1, Iss.5, 2009)

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