Leukemia & Lymphoma, Volume 62, Issue 8 (2021)

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Leukemia & Lymphoma, Volume 62, Issue 8 (2021)

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Commentry

Article Commentary
The quest for validated treatment endpoints in light chain (AL) amyloidosis: composite criteria for a composite disease
Giovanni Palladini & Paolo Milani
Pages: 1793-1794
Published online: 21 Apr 2021
CitationforThe quest for validated treatment endpoints in light chain (AL) amyloidosis: composite criteria for a composite disease | Full Text | References | PDF (242.7 KB) | EPUB
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Reviews

Future directions in Hodgkin lymphoma: checkpoint inhibitors and beyond
Sanjal Desai & Stephen M. Ansell
Pages: 1795-1804
Published online: 18 Feb 2021
AbstractforFuture directions in Hodgkin lymphoma: checkpoint inhibitors and beyond | Full Text | References | PDF (1,008.5 KB) | EPUB
  • 677 Views
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Clinical application of genomics in Waldenström macroglobulinemia
Andrew R. Branagan, Mathew Lei, Steven P. Treon & Jorge J. Castillo
Pages: 1805-1815
Published online: 11 Feb 2021
AbstractforClinical application of genomics in Waldenström macroglobulinemia | Full Text | References | PDF (1.2 MB) | EPUB
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Original Articles

Article
Risk-adapted, ofatumumab-based chemoimmunotherapy and consolidation in treatment-naïve chronic lymphocytic leukemia: a phase 2 study
Sanjal Desai, Clifton Mo, Erika M. Gaglione, Constance M. Yuan, Maryalice Stetler-Stevenson, Xin Tian, Irina Maric, Laura Wake, Mohammed Z. Farooqui, Dennis C. Drinkwater, Susan Soto, Janet Valdez, Thomas E. Hughes, Pia Nierman, Jennifer Lotter, Gerald E. Marti, Christopher Pleyer, Clare Sun, Jeanine Superata, Cydney Nichols, Sarah E. M. Herman, Margaret A. Lindorfer, Ronald P. Taylor, Adrian Wiestner & Inhye E. Ahn
Pages: 1816-1827
Published online: 02 Mar 2021
AbstractforRisk-adapted, ofatumumab-based chemoimmunotherapy and consolidation in treatment-naïve chronic lymphocytic leukemia: a phase 2 study | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 262 Views
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Article
Intensity of antigen expression reflects IGHV mutational status and Dohner-defined prognostic categories in chronic lymphocytic leukemia, monoclonal B-cell lymphocytosis, and small lymphocytic lymphoma
Jayalakshmi Balakrishna, Neil Basumallik, Robert Matulonis, Drake Scott, Dalia Salem, Gregory Jasper, Adrian Wiestner, Maryalice Stetler-Stevenson, Gerald Marti, Clare Sun & Constance M. Yuan
Pages: 1828-1839
Published online: 18 Mar 2021
AbstractforIntensity of antigen expression reflects IGHV mutational status and Dohner-defined prognostic categories in chronic lymphocytic leukemia, monoclonal B-cell lymphocytosis, and small lymphocytic lymphoma | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 255 Views
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Article
Stage I–II diffuse large B-cell lymphoma treated with rituximab and chemotherapy with or without radiotherapy
Michael S. Binkley, Susan M. Hiniker, Sheren Younes, Christopher Yoo, Anjali Wignarajah, Michael Jin, H. Henry Guo, Neel K. Gupta, Yasodha Natkunam, Ranjana H. Advani & Richard T. Hoppe
Pages: 1840-1849
Published online: 23 Feb 2021
AbstractforStage I–II diffuse large B-cell lymphoma treated with rituximab and chemotherapy with or without radiotherapy | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 256 Views
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Article
Evaluation of the prognostic utility of bone marrow biopsy in diffuse large B-Cell lymphoma in the SEER-Medicare dataset
Danny Luan, Yiyuan Wu, Jordan Goldstein, Sarah Rutherford, John P. Leonard & Peter Martin
Pages: 1850-1859
Published online: 25 Feb 2021
AbstractforEvaluation of the prognostic utility of bone marrow biopsy in diffuse large B-Cell lymphoma in the SEER-Medicare dataset | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 268 Views
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Article
Perceptions of clinical care and research among African-American patients with lymphoma
Kaylin V. Dance, Conner B. Imbody, Lillian Chen, Lorna McNeill, Jackelyn B. Payne & Christopher R. Flowers
Pages: 1860-1868
Published online: 28 Feb 2021
AbstractforPerceptions of clinical care and research among African-American patients with lymphoma | Full Text | References | PDF (933.9 KB) | EPUB
  • 447 Views
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Article
Progression-free survival at 24 months as a predictor of survival outcomes after CHOP treatment in patients with peripheral T-cell lymphoma: a single-center validation study in a Japanese population
Yuko Shirouchi, Masahiro Yokoyama, Takanori Fukuta, Hideki Uryu, Noriko Nishimura, Yuko Mishima, Norihito Inoue, Naoko Tsuyama, Kengo Takeuchi & Yasuhito Terui
Pages: 1869-1876
Published online: 10 Mar 2021
AbstractforProgression-free survival at 24 months as a predictor of survival outcomes after CHOP treatment in patients with peripheral T-cell lymphoma: a single-center validation study in a Japanese population | Full Text | References | PDF (984 KB) | EPUB | Supplemental
  • 160 Views
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Article
Clinical characteristics and outcomes of black patients with mycosis fungoides and Sézary syndrome: a subgroup analysis of the phase III MAVORIC trial
William T. Johnson, Saritha Kartan, Kelsey Sokol, Neda Nikbakht & Pierluigi Porcu
Pages: 1877-1883
Published online: 22 Feb 2021
AbstractforClinical characteristics and outcomes of black patients with mycosis fungoides and Sézary syndrome: a subgroup analysis of the phase III MAVORIC trial | Full Text | References | PDF (1.2 MB) | EPUB
  • 269 Views
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Article
miR-145-5p exerts anti-tumor effects in diffuse large B-cell lymphoma by regulating S1PR1/STAT3/AKT pathway
Yuanmei Gao & Xiaojuan Ding
Pages: 1884-1891
Published online: 13 Mar 2021
AbstractformiR-145-5p exerts anti-tumor effects in diffuse large B-cell lymphoma by regulating S1PR1/STAT3/AKT pathway | Full Text | References | PDF (2.3 MB) | EPUB
  • 257 Views
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Article
Validation of the composite organ and hematologic response model for prognostic prediction in a Chinese light chain amyloidosis cohort
Kai-ni Shen, Hui-lei Miao, Lu Zhang, Jun Feng, Xin-xin Cao & Jian Li
Pages: 1892-1896
Published online: 18 Feb 2021
AbstractforValidation of the composite organ and hematologic response model for prognostic prediction in a Chinese light chain amyloidosis cohort | Full Text | References | PDF (829.6 KB) | EPUB
  • 151 Views
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Article
Subcutaneous bortezomib-containing regimens as up-front treatment of newly diagnosed transplant-eligible multiple myeloma patients: a retrospective, non-interventional observational study
Ilaria Rizzello, Michele Cavo, Luca Dozza, Elena Rivolti, Maria Teresa Petrucci, Valerio De Stefano, Elisabetta Antonioli, Patrizia Tosi, Mattia D’Agostino, Sonia Morè, Alessandro Gozzetti, Michele Cea, Simona Barbato, Paola Tacchetti, Lucia Pantani, Katia Mancuso, Serena Rocchi, Gabriella De Cicco, Alessio Fusco & Elena Zamagni
Pages: 1897-1906
Published online: 18 Mar 2021
AbstractforSubcutaneous bortezomib-containing regimens as up-front treatment of newly diagnosed transplant-eligible multiple myeloma patients: a retrospective, non-interventional observational study | Full Text | References | PDF (926.6 KB) | EPUB
  • 218 Views
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Article
Expression levels of HLA-DR in acute myeloid leukemia: implications for antigenicity and clinical outcome
Malte Roerden, Melanie Märklin, Helmut R. Salih, Wolfgang A. Bethge, Reinhild Klein, Hans-Georg Rammensee, Annika Nelde & Juliane S. Walz
Pages: 1907-1919
Published online: 02 Mar 2021
AbstractforExpression levels of HLA-DR in acute myeloid leukemia: implications for antigenicity and clinical outcome | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 480 Views
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Article
Decitabine combined with low dose idarubicin and cytarabine (D-IA) followed by allo-HSCT improves acute myeloid leukemia and higher-risk myelodysplastic syndrome patient outcomes: results from a retrospective study
Weilai Xu, Li Ye, Chen Mei, Xin-ping Zhou, Yanling Ren, Liya Ma, Xinnong Ye, Chenxi Lu, Jie Jin & Hong-yan Tong
Pages: 1920-1929
Published online: 07 Mar 2021
AbstractforDecitabine combined with low dose idarubicin and cytarabine (D-IA) followed by allo-HSCT improves acute myeloid leukemia and higher-risk myelodysplastic syndrome patient outcomes: results from a retrospective study | Full Text | References | PDF (1.3 MB) | EPUB
  • 206 Views
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Article
Allogeneic hematopoietic stem cell transplantation for therapy-related myeloid neoplasms following treatment of a lymphoid malignancy
Daniela V. Wenge, Klaus Wethmar, Jan-Henrik Mikesch, Christian Reicherts, Christoph Schliemann, Rolf Mesters, Torsten Kessler, Cyrus Khandanpour, Andrea Kerkhoff, Norbert Schmitz, Wolfgang E. Berdel, Georg Lenz & Matthias Stelljes
Pages: 1930-1939
Published online: 29 Mar 2021
AbstractforAllogeneic hematopoietic stem cell transplantation for therapy-related myeloid neoplasms following treatment of a lymphoid malignancy | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 189 Views
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Article
Neutropenia in adult acute myeloid leukemia patients represents a powerful risk factor for COVID-19 related mortality
Maximilian Stahl, Varun Narendra, Justin Jee, Andriy Derkach, Molly Maloy, Mark B. Geyer, Anthony R. Mato, Lindsey E. Roeker, Martin S. Tallman, Gunjan L. Shah, Anthony Daniyan & Aaron D. Goldberg
Pages: 1940-1948
Published online: 28 Jun 2021
AbstractforNeutropenia in adult acute myeloid leukemia patients represents a powerful risk factor for COVID-19 related mortality | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 319 Views
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Article
Early mortality and overall survival in acute promyelocytic leukemia: do real-world data match results of the clinical trials?
Prajwal Dhakal, Elizabeth Lyden, Venkat Rajasurya, Amer M. Zeidan, Chakra Chaulagain, Krishna Gundabolu & Vijaya Raj Bhatt
Pages: 1949-1957
Published online: 12 Mar 2021
AbstractforEarly mortality and overall survival in acute promyelocytic leukemia: do real-world data match results of the clinical trials? | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 245 Views
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Article
Mutational spectrum of de novo NPM1-mutated acute myeloid leukemia patients older than 75 years
Louise Pettersson, Benjamin Holmgren, Gunnar Juliusson, Vladimir Lj Lazarevic & Mats Ehinger
Pages: 1958-1966
Published online: 12 Mar 2021
AbstractforMutational spectrum of de novo NPM1-mutated acute myeloid leukemia patients older than 75 years | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 2195 Views
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Open Access
Article
Associations between complete remission and 2- to 3-year survival following 7 + 3 induction for acute myeloid leukemia
Megan Othus, Guillermo Garcia-Manero, John Godwin, James Weick, Derek Stirewalt, Frederick Appelbaum, Harry Erba & Elihu Estey
Pages: 1967-1972
Published online: 10 Mar 2021
AbstractforAssociations between complete remission and 2- to 3-year survival following 7 + 3 induction for acute myeloid leukemia | Full Text | References | PDF (722.1 KB) | EPUB | Supplemental
  • 147 Views
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Article
Is there an impact of measurable residual disease as assessed by multiparameter flow cytometry on survival of AML patients treated in clinical practice? A population-based study
Aldana Rosso, Gunnar Juliusson, Fryderyk Lorenz, Sören Lehmann, Åsa Derolf, Stefan Deneberg, Martin Jädersten, Petar Antunovic, Jörg Cammenga, Lars Möllgård, Lovisa Wennström, Emma Ölander, Mats Ehinger, Linda Fogelstrand, Martin Höglund & Vladimir Lj Lazarevic
Pages: 1973-1981
Published online: 10 Mar 2021
AbstractforIs there an impact of measurable residual disease as assessed by multiparameter flow cytometry on survival of AML patients treated in clinical practice? A population-based study | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 1935 Views
  • 4 CrossRef citations
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Open Access
Article
Grade 3–4 cytokine release syndrome is associated with poor survival in haploidentical peripheral blood stem cell transplantation
Dipenkumar Modi, Omar Albanyan, Seongho Kim, Abhinav Deol, Lois Ayash, Voravit Ratanatharathorn & Joseph P. Uberti
Pages: 1982-1989
Published online: 24 Feb 2021
AbstractforGrade 3–4 cytokine release syndrome is associated with poor survival in haploidentical peripheral blood stem cell transplantation | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 375 Views
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Letters to the Editor

Letter
Comparative pharmacokinetic analysis of the blood-brain barrier penetration of dasatinib and ponatinib in mice
Karthik Ravi, Andrea Franson, Morgan J. Homan, Holly Roberts, Manjunath P. Pai, Zachary Miklja, Miao He, Bo Wen, Lydia L. Benitez, Anthony J. Perissinotti, Dale L. Bixby, Carl Koschmann & Bernard L. Marini
Pages: 1990-1994
Published online: 07 Mar 2021
First Page PreviewforComparative pharmacokinetic analysis of the blood-brain barrier penetration of dasatinib and ponatinib in mice | Full Text | References | PDF (870.1 KB) | EPUB | Supplemental
  • 761 Views
  • 5 CrossRef citations
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Letter
Ongoing excellent outcomes with reduced toxicities following integration of molecular targeted therapies in pediatric anaplastic large cell lymphoma
Peter McCarthy, John Harford, Aengus O’Marcaigh, Andrea Malone, Pamela Evans, Aoife Sills, Lorna Storey, Sean Rooney, David Betts, Maureen J. O’Sullivan, Michael McDermott, Jonathan Bond, Amélie Trinquand & Owen P. Smith
Pages: 1995-1999
Published online: 08 Mar 2021
First Page PreviewforOngoing excellent outcomes with reduced toxicities following integration of molecular targeted therapies in pediatric anaplastic large cell lymphoma | Full Text | References | PDF (617.2 KB) | EPUB | Supplemental
  • 174 Views
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Letter
Inflammatory demyelinating polyneuropathies and lymphoma: clues to diagnosis and therapy
Nicolas Noel, Guillemette Beaudonnet, Cécile Cauquil, Alice Laurenge, Mathilde De Menthon, Céline Labeyrie, Pascale Chrétien, Clovis Adam, Salima Hacein-Bey-Abina, Cécile Goujard, Olivier Lambotte & David Adams
Pages: 2000-2004
Published online: 24 Feb 2021
First Page PreviewforInflammatory demyelinating polyneuropathies and lymphoma: clues to diagnosis and therapy | Full Text | References | PDF (479 KB) | EPUB | Supplemental
  • 121 Views
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Letter
Bioinformatic gene expression analysis demonstrates a limited number of multiple myeloma specific therapeutic targets
Murari Ramesh, James Favaloro, Christian Bryant, Phoebe Joy Ho & Edward Abadir
Pages: 2005-2009
Published online: 20 Feb 2021
First Page PreviewforBioinformatic gene expression analysis demonstrates a limited number of multiple myeloma specific therapeutic targets | Full Text | References | PDF (767.8 KB) | EPUB
  • 198 Views
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Letter
Primary cutaneous lymphoma: a population-based cancer registry descriptive study of 155 consecutive cases diagnosed between 1979 and 2016
Laure Fréchet, Anne Sophie Woronoff, Aurélie Gérazime, Eve Puzenat, Anne Sophie Dupond, Charlée Nardin, Dragos Popescu & François Aubin
Pages: 2010-2013
Published online: 08 Mar 2021
First Page PreviewforPrimary cutaneous lymphoma: a population-based cancer registry descriptive study of 155 consecutive cases diagnosed between 1979 and 2016 | Full Text | References | PDF (590.8 KB) | EPUB
  • 57 Views
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Letter
Treatment intensity and survival trends among real-world elderly AML patients diagnosed in the period 2001–2016: a Danish nationwide cohort study
Therese Maria Henriette Naur, Lasse Hjort Jakobsen, Anne Stidsholt Roug, Tarec Christoffer El-Galaly, Claus Werenberg Marcher, Jan Maxwell Nørgaard, Kim Theilgaard-Mönch, Peter Møller, Claudia Schöllkopf & Marianne Tang Severinsen
Pages: 2014-2017
Published online: 12 Mar 2021
First Page PreviewforTreatment intensity and survival trends among real-world elderly AML patients diagnosed in the period 2001–2016: a Danish nationwide cohort study | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 230 Views
  • 1 CrossRef citations
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Letter
A single-tube multiplex method for monitoring mutations in cysteine 481 of Bruton Tyrosine Kinase (BTK) gene in chronic lymphocytic leukemia patients treated with ibrutinib
Rossana Maffei, Stefania Fiorcari, Claudio Giacinto Atene, Silvia Martinelli, Lydia Scarfò, Silvia Bonfiglio, Monica Maccaferri, Viktor Ljungström, Patrizia Zucchini, Fabio Forghieri, Leonardo Potenza, Paolo Ghia, Roberto Marasca, Tommaso Trenti, Enrico Tagliafico & Mario Luppi
Pages: 2018-2021
Published online: 04 Mar 2021
First Page PreviewforA single-tube multiplex method for monitoring mutations in cysteine 481 of Bruton Tyrosine Kinase (BTK) gene in chronic lymphocytic leukemia patients treated with ibrutinib | Full Text | References | PDF (482.2 KB) | EPUB
  • 248 Views
  • 2 CrossRef citations
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Letter
Pseudoprogression of triple-hit diffuse large B-cell lymphoma following polatuzumab vedotin-based salvage therapy
Xin Wang, Lacey McIntosh, William J. Selove, Jaroslav Zivny & Jan Cerny
Pages: 2022-2025
Published online: 15 Mar 2021
First Page PreviewforPseudoprogression of triple-hit diffuse large B-cell lymphoma following polatuzumab vedotin-based salvage therapy | Full Text | References | PDF (1.3 MB) | EPUB
  • 340 Views
  • 1 CrossRef citations
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Letter
Cerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient
Aitomi Bittner, Josefine Radke, Dennis Eurich, Edzard Wiener, Sophy Denker, Ioannis Anagnostopoulos, Il-Kang Na, Frank L. Heppner, Lars Bullinger & Clemens A. Schmitt
Pages: 2026-2029
Published online: 22 Feb 2021
First Page PreviewforCerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 307 Views
  • 3 CrossRef citations
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Letter
Prevalence of unexplained erythrocytosis and thrombocytosis – an NHANES analysis
Douglas Tremblay, Naomi Alpert, Emanuela Taioli & John Mascarenhas
Pages: 2030-2033
Published online: 28 Feb 2021
First Page PreviewforPrevalence of unexplained erythrocytosis and thrombocytosis – an NHANES analysis | Full Text | References | PDF (669.7 KB) | EPUB | Supplemental
  • 236 Views
  • 3 CrossRef citations
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Letter
Lessons learned for successful treatment of AML in the second wave of COVID-19 outbreak
A. Ramírez-López, P. Lázaro del Campo, K. Humala, B. De la Cruz Benito, I. Sánchez-Vadillo, A. López de la Guía, R. de Paz Arias, V. Jiménez-Yuste & M. Canales
Pages: 2034-2036
Published online: 28 Feb 2021
First Page PreviewforLessons learned for successful treatment of AML in the second wave of COVID-19 outbreak | Full Text | References | PDF (729.3 KB) | EPUB
  • 315 Views
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Letter
Severe IgA-mediated autoimmune hemolytic anemia triggered by SARS-CoV-2 infection
Aude Mausoleo, Soledad Henriquez, Cécile Goujard, Anne-Marie Roque-Afonso, Nicolas Noel & Olivier Lambotte
Pages: 2037-2039
Published online: 22 Feb 2021
First Page PreviewforSevere IgA-mediated autoimmune hemolytic anemia triggered by SARS-CoV-2 infection | Full Text | References | PDF (514.6 KB) | EPUB
  • 139 Views
  • 1 CrossRef citations
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Letter
The safety and efficacy of dasatinib plus nivolumab in patients with previously treated chronic myeloid leukemia: results from a phase 1b dose-escalation study
Joaquín Martínez-López, Satu Mustjoki, Kimmo Porkka, Rebecca B. Klisovic, Dominik Wolf, Lambert Busque, Juan Carlos Hernández-Boluda, Rene Swanink, Patricia Martin Regueira & Jeffrey H. Lipton
Pages: 2040-2043
Published online: 02 Mar 2021
First Page PreviewforThe safety and efficacy of dasatinib plus nivolumab in patients with previously treated chronic myeloid leukemia: results from a phase 1b dose-escalation study | Full Text | References | PDF (684.5 KB) | EPUB | Supplemental
  • 449 Views
  • 3 CrossRef citations
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Letter
Successful and durable response of primary CNS T-cell lymphoma to upfront temozolomide monotherapy
Meghna Yalamanchi, Akanksha Sharma, Minh Nguyen, Judy Truong, Jose A. Carrillo, Naveed Wagle, Jaya M. Gill & Santosh Kesari
Pages: 2044-2046
Published online: 21 Feb 2021
First Page PreviewforSuccessful and durable response of primary CNS T-cell lymphoma to upfront temozolomide monotherapy | Full Text | References | PDF (695.3 KB) | EPUB
  • 172 Views
  • 1 CrossRef citations
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