Autophagy, Volume 11, Issue 9 (2015)

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Autophagy, Volume 11, Issue 9 (2015)

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Editor's Corner

Editorial
TP53INP2/DOR protein chaperones deacetylated nuclear LC3 to the cytoplasm to promote macroautophagy
Xu Liu & Daniel J Klionsky
Pages: 1441-1442
Published online: 18 Sep 2015
CitationforTP53INP2/DOR protein chaperones deacetylated nuclear LC3 to the cytoplasm to promote macroautophagy | Full Text | References | PDF (46.5 KB)
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Review

Review
Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease
Ziv Gan-Or, Patrick A Dion & Guy A Rouleau
Pages: 1443-1457
Published online: 18 Sep 2015
AbstractforGenetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease | Full Text | References | PDF (521.2 KB)
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Basic Brief Report

Brief Report
Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy
Stefan Drießen, Niklas Berleth, Olena Friesen, Antje S Löffler, Philip Böhler, Nora Hieke, Fabian Stuhldreier, Christoph Peter, Kay O Schink, Sebastian W Schultz, Harald Stenmark, Petter Holland, Anne Simonsen, Sebastian Wesselborg & Björn Stork
Pages: 1458-1470
Published online: 18 Sep 2015
AbstractforDeubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy | Full Text | References | PDF (1 MB) | Supplemental
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Brief Report
Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells
Nora Hieke, Antje S Löffler, Takeshi Kaizuka, Niklas Berleth, Philip Böhler, Stefan Drießen, Fabian Stuhldreier, Olena Friesen, Kaivon Assani, Katharina Schmitz, Christoph Peter, Britta Diedrich, Jörn Dengjel, Petter Holland, Anne Simonsen, Sebastian Wesselborg, Noboru Mizushima & Björn Stork
Pages: 1471-1483
Published online: 18 Sep 2015
AbstractforExpression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells | Full Text | References | PDF (1 MB) | Supplemental
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Basic Research Paper

Article
Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy
Cathrin Meissner, Holger Lorenz, Beate Hehn & Marius K Lemberg
Pages: 1484-1498
Published online: 18 Sep 2015
AbstractforIntramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Disruption of the ribosomal P complex leads to stress-induced autophagy
Ana Artero-Castro, Mileidys Perez-Alea, Andrea Feliciano, Jose A Leal, Mónica Genestar, Josep Castellvi, Vicente Peg, Santiago Ramón y Cajal & Matilde E LLeonart
Pages: 1499-1519
Published online: 18 Sep 2015
AbstractforDisruption of the ribosomal P complex leads to stress-induced autophagy | Full Text | References | PDF (1.5 MB) | Supplemental
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Article
Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy
Kana Unuma, Toshihiko Aki, Takeshi Funakoshi, Kyoko Hashimoto & Koichi Uemura
Pages: 1520-1536
Published online: 18 Sep 2015
AbstractforExtrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy | Full Text | References | PDF (1.5 MB)
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Article
Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury
Rebecca J Godar, Xiucui Ma, Haiyan Liu, John T Murphy, Carla J Weinheimer, Attila Kovacs, Seth D Crosby, Paul Saftig & Abhinav Diwan
Pages: 1537-1560
Published online: 18 Sep 2015
AbstractforRepetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury | Full Text | References | PDF (2.6 MB) | Supplemental
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Article
Long-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms
Monica Prado, Nina Eickel, Mariana De Niz, Anna Heitmann, Carolina Agop-Nersesian, Rahel Wacker, Jacqueline Schmuckli-Maurer, Reto Caldelari, Chris J Janse, Shahid M Khan, Jürgen May, Christian G Meyer & Volker T Heussler
Pages: 1561-1579
Published online: 18 Sep 2015
AbstractforLong-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms | Full Text | References | PDF (1.9 MB) | Supplemental
  • 4396 Views
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Open Access
Article
Structure of yeast Ape1 and its role in autophagic vesicle formation
Ming-Yuan Su, Wen-Hsin Peng, Meng-Ru Ho, Shih-Chieh Su, Yuan-Chih Chang, Guang-Chao Chen & Chung-I Chang
Pages: 1580-1593
Published online: 18 Sep 2015
AbstractforStructure of yeast Ape1 and its role in autophagic vesicle formation | Full Text | References | PDF (1.6 MB) | Supplemental
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Article
Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner
Phillip T Newton, Karuna K Vuppalapati, Thibault Bouderlique & Andrei S Chagin
Pages: 1594-1607
Published online: 18 Sep 2015
AbstractforPharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner | Full Text | References | PDF (1.3 MB) | Supplemental
  • 4212 Views
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Article
Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33AD251E mutation
Yuanli Zhen & Wei Li
Pages: 1608-1622
Published online: 18 Sep 2015
AbstractforImpairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33AD251E mutation | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA
Wei Xie, Lei Zhang, Haifeng Jiao, Li Guan, Junmin Zha, Xiaotong Li, Mian Wu, Zhanxiang Wang, Jiahuai Han & Han You
Pages: 1623-1635
Published online: 18 Sep 2015
AbstractforChaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA | Full Text | References | PDF (1.1 MB) | Supplemental
  • 3402 Views
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Article
The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells
Ida Johansson, Vivi Talstad Monsen, Kristine Pettersen, Jennifer Mildenberger, Kristine Misund, Kai Kaarniranta, Svanhild Schønberg & Geir Bjørkøy
Pages: 1636-1651
Published online: 18 Sep 2015
AbstractforThe marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells | Full Text | References | PDF (908.6 KB) | Supplemental
  • 3702 Views
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Open Access
Article
Evolutionary trends and functional anatomy of the human expanded autophagy network
Andreas Till, Rintaro Saito, Daria Merkurjev, Jing-Jing Liu, Gulam Hussain Syed, Martin Kolnik, Aleem Siddiqui, Martin Glas, Björn Scheffler, Trey Ideker & Suresh Subramani
Pages: 1652-1667
Published online: 18 Sep 2015
AbstractforEvolutionary trends and functional anatomy of the human expanded autophagy network | Full Text | References | PDF (1.2 MB) | Supplemental
  • 2103 Views
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Resource

Article
Cross-cancer profiling of molecular alterations within the human autophagy interaction network
Chandra B Lebovitz, A Gordon Robertson, Rodrigo Goya, Steven J Jones, Ryan D Morin, Marco A Marra & Sharon M Gorski
Pages: 1668-1687
Published online: 18 Sep 2015
AbstractforCross-cancer profiling of molecular alterations within the human autophagy interaction network | Full Text | References | PDF (1.9 MB) | Supplemental
  • 5252 Views
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Translational Research Paper

Article
Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages
Rokeya Sultana Rekha, SSV Jagadeeswara Rao Muvva, Min Wan, Rubhana Raqib, Peter Bergman, Susanna Brighenti, Gudmundur H Gudmundsson & Birgitta Agerberth
Pages: 1688-1699
Published online: 18 Sep 2015
AbstractforPhenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages | Full Text | References | PDF (1 MB) | Supplemental
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Autophagic Punctum

Article
The PARK2/Parkin receptor on damaged mitochondria revisited—uncovering the role of phosphorylated ubiquitin chains
Noriyuki Matsuda & Keiji Tanaka
Pages: 1700-1701
Published online: 18 Sep 2015
AbstractforThe PARK2/Parkin receptor on damaged mitochondria revisited—uncovering the role of phosphorylated ubiquitin chains | Full Text | PDF (181.3 KB)
  • 1275 Views
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Article
WHAMM links actin assembly via the Arp2/3 complex to autophagy
David J Kast & Roberto Dominguez
Pages: 1702-1704
Published online: 18 Sep 2015
AbstractforWHAMM links actin assembly via the Arp2/3 complex to autophagy | Full Text | PDF (208 KB)
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Article Commentary
AMBRA1: When autophagy meets cell proliferation
Valentina Cianfanelli & Francesco Cecconi
Pages: 1705-1707
Published online: 18 Sep 2015
AbstractforAMBRA1: When autophagy meets cell proliferation | Full Text | PDF (129.2 KB)
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Corrigendum

Correction
Corrigendum
Page: 1708
Published online: 18 Sep 2015
CitationforCorrigendum | Full Text | PDF (77.8 KB)
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