Autophagy, Volume 12, Issue 5 (2016)

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Autophagy, Volume 12, Issue 5 (2016)

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Basic Research Paper

Article
A role for ABCG2 beyond drug transport: Regulation of autophagy
Rui Ding, Shengkan Jin, Kirk Pabon & Kathleen W. Scotto
Pages: 737-751
Published online: 16 Mar 2016
AbstractforA role for ABCG2 beyond drug transport: Regulation of autophagy | Full Text | References | PDF (1.4 MB)
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Article
Sexual dimorphism in activation of placental autophagy in obese women with evidence for fetal programming from a placenta-specific mouse model
Sribalasubashini Muralimanoharan, Xiaoli Gao, Susan Weintraub, Leslie Myatt & Alina Maloyan
Pages: 752-769
Published online: 17 Mar 2016
AbstractforSexual dimorphism in activation of placental autophagy in obese women with evidence for fetal programming from a placenta-specific mouse model | Full Text | References | PDF (1.7 MB) | Supplemental
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Article
Activation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasive Escherichia coli infection
Alexis Bretin, Jessica Carrière, Guillaume Dalmasso, Agnès Bergougnoux, Wafa B'chir, Anne-Catherine Maurin, Stefan Müller, Frank Seibold, Nicolas Barnich, Alain Bruhat, Arlette Darfeuille-Michaud & Hang Thi Thu Nguyen
Pages: 770-783
Published online: 12 Apr 2016
AbstractforActivation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasive Escherichia coli infection | Full Text | References | PDF (1.6 MB) | Supplemental
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Open Access
Article
Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease
Sung Min Son, Moon-Yong Cha, Heesun Choi, Seokjo Kang, Hyunjung Choi, Myung-Shik Lee, Sun Ah Park & Inhee Mook-Jung
Pages: 784-800
Published online: 12 Apr 2016
AbstractforInsulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease | Full Text | References | PDF (1.6 MB) | Supplemental
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Article
Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule
Takeshi Yamamoto, Yoshitsugu Takabatake, Tomonori Kimura, Atsushi Takahashi, Tomoko Namba, Jun Matsuda, Satoshi Minami, Jun-ya Kaimori, Isao Matsui, Harumi Kitamura, Taiji Matsusaka, Fumio Niimura, Motoko Yanagita, Yoshitaka Isaka & Hiromi Rakugi
Pages: 801-813
Published online: 12 Apr 2016
AbstractforTime-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule | Full Text | References | PDF (1.7 MB) | Supplemental
  • 3833 Views
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Article
Autophagy is required for ectoplasmic specialization assembly in sertoli cells
Chao Liu, Hongna Wang, Yongliang Shang, Weixiao Liu, Zhenhua Song, Haichao Zhao, Lina Wang, Pengfei Jia, Fengyi Gao, Zhiliang Xu, Lin Yang, Fei Gao & Wei Li
Pages: 814-832
Published online: 12 Apr 2016
AbstractforAutophagy is required for ectoplasmic specialization assembly in sertoli cells | Full Text | References | PDF (2.7 MB) | Supplemental
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Article
Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure
Elisabeth Corcelle-Termeau, Signe Diness Vindeløv, Saara Hämälistö, Baharia Mograbi, Anne Keldsbo, Jan Hinrich Bräsen, Elena Favaro, Dieter Adam, Piotr Szyniarowski, Paul Hofman, Stefan Krautwald, Thomas Farkas, Nikolaj H.T. Petersen, Mikkel Rohde, Andreas Linkermann & Marja Jäättelä
Pages: 833-849
Published online: 12 Apr 2016
AbstractforExcess sphingomyelin disturbs ATG9A trafficking and autophagosome closure | Full Text | References | PDF (2.6 MB) | Supplemental
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Open Access
Article
Ferritinophagy drives uropathogenic Escherichia coli persistence in bladder epithelial cells
Kyle A. Bauckman & Indira U. Mysorekar
Pages: 850-863
Published online: 22 Mar 2016
AbstractforFerritinophagy drives uropathogenic Escherichia coli persistence in bladder epithelial cells | Full Text | References | PDF (1.8 MB) | Supplemental
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Clinical Research Paper

Article
The presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer
Sylvain Ladoire, David Enot, Laura Senovilla, François Ghiringhelli, Vichnou Poirier-Colame, Kariman Chaba, Michaela Semeraro, Marie Chaix, Frédérique Penault-Llorca, Laurent Arnould, Marie Laure Poillot, Patrick Arveux, Suzette Delaloge, Fabrice Andre, Laurence Zitvogel & Guido Kroemer
Pages: 864-875
Published online: 12 Apr 2016
AbstractforThe presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer | Full Text | References | PDF (1.5 MB) | Supplemental
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Protocol

Article
hfAIM: A reliable bioinformatics approach for in silico genome-wide identification of autophagy-associated Atg8-interacting motifs in various organisms
Qingjun Xie, Oren Tzfadia, Matan Levy, Efrat Weithorn, Hadas Peled-Zehavi, Thomas Van Parys, Yves Van de Peer & Gad Galili
Pages: 876-887
Published online: 12 Apr 2016
AbstractforhfAIM: A reliable bioinformatics approach for in silico genome-wide identification of autophagy-associated Atg8-interacting motifs in various organisms | Full Text | References | PDF (905.9 KB) | Supplemental
  • 2818 Views
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Autophagic Puncta

Article Commentary
Melanin targets LC3-associated phagocytosis (LAP): A novel pathogenetic mechanism in fungal disease
Georgios Chamilos, Tonia Akoumianaki, Irene Kyrmizi, Axel Brakhage, Anne Beauvais & Jean-Paul Latge
Pages: 888-889
Published online: 12 Apr 2016
AbstractforMelanin targets LC3-associated phagocytosis (LAP): A novel pathogenetic mechanism in fungal disease | Full Text | PDF (241.5 KB)
  • 2662 Views
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Article Commentary
KLHL20 links the ubiquitin-proteasome system to autophagy termination
Chin-Chih Liu & Ruey-Hwa Chen
Pages: 890-891
Published online: 12 Apr 2016
AbstractforKLHL20 links the ubiquitin-proteasome system to autophagy termination | Full Text | PDF (230.8 KB)
  • 2189 Views
  • 9 CrossRef citations
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Article Commentary
GABARAP activates ULK1 and traffics from the centrosome dependent on Golgi partners WAC and GOLGA2/GM130
Justin Joachim & Sharon A. Tooze
Pages: 892-893
Published online: 17 Mar 2016
AbstractforGABARAP activates ULK1 and traffics from the centrosome dependent on Golgi partners WAC and GOLGA2/GM130 | Full Text | PDF (357.2 KB)
  • 2424 Views
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Article Commentary
The Atg17-Atg31-Atg29 complex and Atg11 regulate autophagosome-vacuole fusion
Xu Liu & Daniel J. Klionsky
Pages: 894-895
Published online: 17 Mar 2016
AbstractforThe Atg17-Atg31-Atg29 complex and Atg11 regulate autophagosome-vacuole fusion | Full Text | PDF (228.4 KB)
  • 2089 Views
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Article Commentary
Autophagy controls carbon, nitrogen, and redox homeostasis in plants
C. Masclaux-Daubresse
Pages: 896-897
Published online: 12 Apr 2016
AbstractforAutophagy controls carbon, nitrogen, and redox homeostasis in plants | Full Text | PDF (253.4 KB)
  • 1682 Views
  • 23 CrossRef citations
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Article Commentary
How autophagy both activates and inhibits cellular senescence
Chanhee Kang & Stephen J. Elledge
Pages: 898-899
Published online: 29 Apr 2016
AbstractforHow autophagy both activates and inhibits cellular senescence | Full Text | PDF (231 KB)
  • 10154 Views
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Views and Commentaries

Article Commentary
Emerging nexus between RAB GTPases, autophagy and neurodegeneration
Navodita Jain & Subramaniam Ganesh
Pages: 900-904
Published online: 12 Apr 2016
AbstractforEmerging nexus between RAB GTPases, autophagy and neurodegeneration | Full Text | References | PDF (500.3 KB)
  • 2043 Views
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