Autophagy, Volume 14, Issue 11 (2018)

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Autophagy, Volume 14, Issue 11 (2018)

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Editor's Corner

Editorial
Structural basis for extremely strong binding affinity of giant ankyrins to LC3/GABARAP and its application in the inhibition of autophagy
Hana Popelka & Daniel J. Klionsky
Pages: 1847-1849
Published online: 19 Sep 2018
AbstractforStructural basis for extremely strong binding affinity of giant ankyrins to LC3/GABARAP and its application in the inhibition of autophagy | Full Text | References | PDF (681.2 KB)
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Research Paper - Basic Science

Article
Effects of AANAT overexpression on the inflammatory responses and autophagy activity in the cellular and transgenic animal levels
Jingli Tao, Minghui Yang, Hao Wu, Teng Ma, Changjiu He, Menglong Chai, Xiaosheng Zhang, Jinlong Zhang, Fangrong Ding, Sutian Wang, Shoulong Deng, Kuanfeng Zhu, Yukun Song, Pengyun Ji, Haijun Liu, Zhengxing Lian & Guoshi Liu
Pages: 1850-1869
Published online: 04 Aug 2018
AbstractforEffects of AANAT overexpression on the inflammatory responses and autophagy activity in the cellular and transgenic animal levels | Full Text | References | PDF (4.2 MB) | Supplemental
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Research Article

Article
PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5
Dae-Hee Lee, Daeho Kim, Sung Tae Kim, Soyeon Jeong, Jung Lim Kim, Sang Mi Shim, Ah Jung Heo, Xinxin Song, Zong Sheng Guo, David L. Bartlett, Sang Cheul Oh, Junho Lee, Yoshiro Saito, Bo Yeon Kim, Yong Tae Kwon & Yong J. Lee
Pages: 1870-1885
Published online: 23 Jul 2018
AbstractforPARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5 | Full Text | References | PDF (3.2 MB) | Supplemental
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Research Paper - Basic Science

Article
Contractile activity attenuates autophagy suppression and reverses mitochondrial defects in skeletal muscle cells
Alexa Parousis, Heather N. Carter, Claudia Tran, Avigail T. Erlich, Zahra S. Mesbah Moosavi, Marion Pauly & David A. Hood
Pages: 1886-1897
Published online: 04 Aug 2018
AbstractforContractile activity attenuates autophagy suppression and reverses mitochondrial defects in skeletal muscle cells | Full Text | References | PDF (1.7 MB)
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Basic Research Paper

Article
The lysosomal membrane protein LAMP2A promotes autophagic flux and prevents SNCA-induced Parkinson disease-like symptoms in the Drosophila brain
Abdul-Raouf Issa, Jun Sun, Céline Petitgas, Ana Mesquita, Amina Dulac, Marion Robin, Bertrand Mollereau, Andreas Jenny, Baya Chérif-Zahar & Serge Birman
Pages: 1898-1910
Published online: 10 Aug 2018
AbstractforThe lysosomal membrane protein LAMP2A promotes autophagic flux and prevents SNCA-induced Parkinson disease-like symptoms in the Drosophila brain | Full Text | References | PDF (1.6 MB) | Supplemental
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Research Paper - Basic Science

Article
Loss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo
Monika Kustermann, Linda Manta, Christoph Paone, Jochen Kustermann, Ludwig Lausser, Cora Wiesner, Ludwig Eichinger, Christoph S. Clemen, Rolf Schröder, Hans A. Kestler, Marco Sandri, Wolfgang Rottbauer & Steffen Just
Pages: 1911-1927
Published online: 16 Aug 2018
AbstractforLoss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo | Full Text | References | PDF (3.7 MB) | Supplemental
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Open Access
Article
CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection
Kathrin Krause, Kyle Caution, Asmaa Badr, Kaitlin Hamilton, Abdulmuti Saleh, Khushbu Patel, Stephanie Seveau, Luanne Hall-Stoodley, Rana Hegazi, Xiaoli Zhang, Mikhail A. Gavrilin & Amal O. Amer
Pages: 1928-1942
Published online: 31 Aug 2018
AbstractforCASP4/caspase-11 promotes autophagosome formation in response to bacterial infection | Full Text | References | PDF (2.8 MB) | Supplemental
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Open Access
Article
6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway
Yasuomi Urano, Chinatsu Mori, Ayano Fuji, Keito Konno, Takayuki Yamamoto, Shohei Yashirogi, Mayu Ando, Yoshiro Saito & Noriko Noguchi
Pages: 1943-1958
Published online: 16 Aug 2018
Abstractfor6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway | Full Text | References | PDF (2 MB) | Supplemental
  • 7086 Views
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Article
TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose
Yiming Zhang, Cassandra B. Higgins, Allyson L. Mayer, Indira U. Mysorekar, Babak Razani, Mark J. Graham, Paul W. Hruz & Brian J. DeBosch
Pages: 1959-1975
Published online: 06 Aug 2018
AbstractforTFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose | Full Text | References | PDF (3.6 MB) | Supplemental
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Article
USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination
Arishya Sharma, Turkeya Alswillah, Kamini Singh, Payel Chatterjee, Belinda Willard, Monica Venere, Matthew K. Summers & Alexandru Almasan
Pages: 1976-1990
Published online: 10 Aug 2018
AbstractforUSP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination | Full Text | References | PDF (9.9 MB) | Supplemental
  • 5337 Views
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Article
Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis
Yusuke Osonoi, Tomoya Mita, Kosuke Azuma, Kenichi Nakajima, Atsushi Masuyama, Hiromasa Goto, Yuya Nishida, Takeshi Miyatsuka, Yoshio Fujitani, Masato Koike, Masako Mitsumata & Hirotaka Watada
Pages: 1991-2006
Published online: 10 Aug 2018
AbstractforDefective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis | Full Text | References | PDF (3 MB) | Supplemental
  • 4487 Views
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Research Paper - Translational

Article
Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy
Jiwei Wang, Qichao Qi, Wenjing Zhou, Zichao Feng, Bin Huang, Anjing Chen, Di Zhang, Wenjie Li, Qing Zhang, Zheng Jiang, Rolf Bjerkvig, Lars Prestegarden, Frits Thorsen, Xinyu Wang, Xingang Li & Jian Wang
Pages: 2007-2022
Published online: 17 Aug 2018
AbstractforInhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy | Full Text | References | PDF (4 MB) | Supplemental
  • 8843 Views
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Commentary

Article Commentary
PTEN-L puts a brake on mitophagy
Liming Wang, Jigang Wang, Yancheng Tang & Han-Ming Shen
Pages: 2023-2025
Published online: 02 Sep 2018
AbstractforPTEN-L puts a brake on mitophagy | Full Text | References | PDF (503.3 KB)
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Autophagic Punctum

Article Commentary
The BECN1-BCL2 complex regulates insulin secretion and storage in mice
Kenta Kuramoto & Congcong He
Pages: 2026-2028
Published online: 21 Aug 2018
AbstractforThe BECN1-BCL2 complex regulates insulin secretion and storage in mice | Full Text | References | PDF (674.2 KB)
  • 1100 Views
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Commentary

Article Commentary
To save or degrade: balancing proteasome homeostasis to maximize cell survival
Richard S. Marshall & Richard D. Vierstra
Pages: 2029-2031
Published online: 11 Sep 2018
AbstractforTo save or degrade: balancing proteasome homeostasis to maximize cell survival | Full Text | References | PDF (752.9 KB)
  • 1191 Views
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