Autophagy, Volume 17, Issue 5 (2021)

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Autophagy, Volume 17, Issue 5 (2021)

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Editor’s Corner

Article
New functions of a known autophagy regulator: VCP and autophagy initiation
Yuchen Lei & Daniel J. Klionsky
Pages: 1063-1064
Published online: 31 Mar 2021
AbstractforNew functions of a known autophagy regulator: VCP and autophagy initiation | Full Text | References | PDF (219 KB) | EPUB
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Review

Sex differences in autophagy-mediated diseases: toward precision medicine
Dangtong Shang, Lingling Wang, Daniel J. Klionsky, Hanhua Cheng & Rongjia Zhou
Pages: 1065-1076
Published online: 17 Apr 2020
AbstractforSex differences in autophagy-mediated diseases: toward precision medicine | Full Text | References | PDF (3.2 MB) | EPUB
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Autophagy in the physiological endometrium and cancer
Laura Devis-Jauregui, Núria Eritja, Meredith Leigh Davis, Xavier Matias-Guiu & David Llobet-Navàs
Pages: 1077-1095
Published online: 13 May 2020
AbstractforAutophagy in the physiological endometrium and cancer | Full Text | References | PDF (2.9 MB) | EPUB
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Research Paper

Article
PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation
Ming-Yue Wu, Le Liu, Er-Jin Wang, Hai-Tao Xiao, Cui-Zan Cai, Jing Wang, Huanxing Su, Yitao Wang, Jieqiong Tan, Zhuohua Zhang, Juan Wang, Maojing Yao, De-Fang Ouyang, Zhenyu Yue, Min Li, Ye Chen, Zhao-Xiang Bian & Jia-Hong Lu
Pages: 1096-1111
Published online: 19 Mar 2020
AbstractforPI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation | Full Text | References | PDF (8.8 MB) | EPUB | Supplemental
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Article
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation
Cui-Zan Cai, Chuanbin Yang, Xu-Xu Zhuang, Ning-Ning Yuan, Ming-Yue Wu, Jie-Qiong Tan, Ju-Xian Song, King-Ho Cheung, Huanxing Su, Yi-Tao Wang, Bei-Sha Tang, Christian Behrends, Siva Sundara Kumar Durairajan, Zhenyu Yue, Min Li & Jia-Hong Lu
Pages: 1112-1130
Published online: 16 Jun 2020
AbstractforNRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation | Full Text | References | PDF (9.6 MB) | EPUB | Supplemental
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Brief Report

Brief Report
ATG13 dynamics in nonselective autophagy and mitophagy: insights from live imaging studies and mathematical modeling
Piero Dalle Pezze, Eleftherios Karanasios, Varvara Kandia, Maria Manifava, Simon A. Walker, Nicolas Gambardella Le Novère & Nicholas T. Ktistakis
Pages: 1131-1141
Published online: 22 Apr 2020
AbstractforATG13 dynamics in nonselective autophagy and mitophagy: insights from live imaging studies and mathematical modeling | Full Text | References | PDF (5.9 MB) | EPUB | Supplemental
  • 2718 Views
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Research Paper

Article
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses
Yongquan Hu, Hao Chen, Luying Zhang, Xiaoying Lin, Xia Li, Haixia Zhuang, Hualin Fan, Tian Meng, Zhengjie He, Haofeng Huang, Qing Gong, Dongxing Zhu, Yiming Xu, Pengcheng He, Longxuan Li & Du Feng
Pages: 1142-1156
Published online: 19 Apr 2020
AbstractforThe AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses | Full Text | References | PDF (5.8 MB) | EPUB | Supplemental
  • 12694 Views
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Article
Acetylation of STX17 (syntaxin 17) controls autophagosome maturation
Qiuhong Shen, Yin Shi, Jiaqi Liu, Hua Su, Jingtao Huang, Yi Zhang, Chao Peng, Tianhua Zhou, Qiming Sun, Wei Wan & Wei Liu
Pages: 1157-1169
Published online: 15 Apr 2020
AbstractforAcetylation of STX17 (syntaxin 17) controls autophagosome maturation | Full Text | References | PDF (4.9 MB) | EPUB | Supplemental
  • 6398 Views
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Article
Autophagy triggers CTSD (cathepsin D) maturation and localization inside cells to promote apoptosis
Yu-Qin Di, Xiao-Lin Han, Xin-Le Kang, Di Wang, Cai-Hua Chen, Jin-Xing Wang & Xiao-Fan Zhao
Pages: 1170-1192
Published online: 23 Apr 2020
AbstractforAutophagy triggers CTSD (cathepsin D) maturation and localization inside cells to promote apoptosis | Full Text | References | PDF (8.3 MB) | EPUB | Supplemental
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Brief Report

Brief Report
Autophagy-related protein PIK3C3/VPS34 controls T cell metabolism and function
PIK3C3/VPS34 in T cell metabolism and function
Guan Yang, Wenqiang Song, J. Luke Postoak, Jin Chen, Jennifer Martinez, Jianhua Zhang, Lan Wu & Luc Van Kaer
Pages: 1193-1204
Published online: 16 Apr 2020
AbstractforAutophagy-related protein PIK3C3/VPS34 controls T cell metabolism and function | Full Text | References | PDF (6.4 MB) | EPUB | Supplemental
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Research Paper

Article
Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice
Myoung Seok Ko, Ji Young Yun, In-Jeoung Baek, Jung Eun Jang, Jung Jin Hwang, Seung Eun Lee, Seung-Ho Heo, David A. Bader, Chul-Ho Lee, Jaeseok Han, Jong-Seok Moon, Jae Man Lee, Eun-Gyoung Hong, In-Kyu Lee, Seong Who Kim, Joong Yeol Park, Sean M. Hartig, Un Jung Kang, David D. Moore, Eun Hee Koh & Ki-up Lee
Pages: 1205-1221
Published online: 13 May 2020
AbstractforMitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice | Full Text | References | PDF (5.3 MB) | EPUB | Supplemental
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Article
1-phenyl 2-thiourea (PTU) activates autophagy in zebrafish embryos
Xiang-Ke Chen, Joseph Shiu-Kwong Kwan, Raymond Chuen-Chung Chang & Alvin Chun-Hang Ma
Pages: 1222-1231
Published online: 22 Apr 2020
Abstractfor1-phenyl 2-thiourea (PTU) activates autophagy in zebrafish embryos | Full Text | References | PDF (4.7 MB) | EPUB | Supplemental
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Article
Dimerization of mitophagy receptor BNIP3L/NIX is essential for recruitment of autophagic machinery
Mija Marinković, Matilda Šprung & Ivana Novak
Pages: 1232-1243
Published online: 24 Apr 2020
AbstractforDimerization of mitophagy receptor BNIP3L/NIX is essential for recruitment of autophagic machinery | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
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Article
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation
Christian W. Keller, Monika B. Kotur, Sarah Mundt, Nikolaos Dokalis, Laure-Anne Ligeon, Ajay M. Shah, Marco Prinz, Burkhard Becher, Christian Münz & Jan D. Lünemann
Pages: 1244-1258
Published online: 13 May 2020
AbstractforCYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
  • 5102 Views
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Article
The DNA methyltransferase DNMT3A contributes to autophagy long-term memory
Patricia González-Rodríguez, Mathilde Cheray, Jens Füllgrabe, Maria Salli, Pinelopi Engskog-Vlachos, Lily Keane, Virginia Cunha, Agata Lupa, Wenbo Li, Qi Ma, Kristian Dreij, Michael G. Rosenfeld & Bertrand Joseph
Pages: 1259-1277
Published online: 14 Sep 2020
AbstractforThe DNA methyltransferase DNMT3A contributes to autophagy long-term memory | Full Text | References | PDF (6.4 MB) | EPUB | Supplemental
  • 7151 Views
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Open Access

Autophagic Punctum

Article
Targeting autophagy as a therapeutic strategy to prevent dopamine neuron loss in early stages of Alzheimer disease
Annalisa Nobili, Livia La Barbera & Marcello D’Amelio
Pages: 1278-1280
Published online: 05 Apr 2021
AbstractforTargeting autophagy as a therapeutic strategy to prevent dopamine neuron loss in early stages of Alzheimer disease | Full Text | References | PDF (564.7 KB) | EPUB
  • 1353 Views
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Article
Autophagosome content profiling reveals receptor-specific cargo candidates
Susanne Zellner & Christian Behrends
Pages: 1281-1283
Published online: 05 Apr 2021
AbstractforAutophagosome content profiling reveals receptor-specific cargo candidates | Full Text | References | PDF (474.2 KB) | EPUB
  • 1980 Views
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Article
SPATA33 functions as a mitophagy receptor in mammalian germline
Xu Xu, Ying Zhang, Hanhua Cheng & Rongjia Zhou
Pages: 1284-1286
Published online: 05 Apr 2021
AbstractforSPATA33 functions as a mitophagy receptor in mammalian germline | Full Text | References | PDF (483.9 KB) | EPUB
  • 1200 Views
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Article
Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P2 is required for autophagic lysosome reformation and protection from skeletal muscle disease
Matthew J. Eramo, Rajendra Gurung, Christina A. Mitchell & Meagan J. McGrath
Pages: 1287-1289
Published online: 20 Apr 2021
AbstractforBidirectional interconversion between PtdIns4P and PtdIns(4,5)P2 is required for autophagic lysosome reformation and protection from skeletal muscle disease | Full Text | References | PDF (500 KB) | EPUB
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Article
Macropinocytosis: the big drinker behind cancer cell self-consumption
Hua Su, Fei Yang, Beicheng Sun & Michael Karin
Pages: 1290-1291
Published online: 27 Apr 2021
AbstractforMacropinocytosis: the big drinker behind cancer cell self-consumption | Full Text | References | PDF (160.7 KB) | EPUB
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