Cancer Biology & Therapy, Volume 18, Issue 8 (2017)

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Cancer Biology & Therapy, Volume 18, Issue 8 (2017)

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Journal Club

Article
Discussing the predictive, prognostic, and therapeutic value of germline DNA-repair gene mutations in metastatic prostate cancer patients
Ralph J. Hauke Jr., Tristan M. Sissung & William D. Figg
Pages: 545-546
Published online: 28 Jul 2017
AbstractforDiscussing the predictive, prognostic, and therapeutic value of germline DNA-repair gene mutations in metastatic prostate cancer patients | Full Text | References | PDF (268.7 KB)
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Bedside to Bench Report

Report
A rapid and systemic complete response to stereotactic body radiation therapy and pembrolizumab in a patient with metastatic renal cell carcinoma
Guozhu Xie, Di Gu, Lanfang Zhang, Shijun Chen & Dehua Wu
Pages: 547-551
Published online: 28 Jul 2017
AbstractforA rapid and systemic complete response to stereotactic body radiation therapy and pembrolizumab in a patient with metastatic renal cell carcinoma | Full Text | References | PDF (714.2 KB)
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Research Paper

Article
SUMOylation of HSP27 by small ubiquitin-like modifier 2/3 promotes proliferation and invasion of hepatocellular carcinoma cells
Haize Ge, Juan Du, Jingman Xu, Xiangliang Meng, Jinchuan Tian, Jie Yang & Huimin Liang
Pages: 552-559
Published online: 26 Sep 2017
AbstractforSUMOylation of HSP27 by small ubiquitin-like modifier 2/3 promotes proliferation and invasion of hepatocellular carcinoma cells | Full Text | References | PDF (924.7 KB) | Supplemental
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Article
Deletion of eIF2β lysine stretches creates a dominant negative that affects the translation and proliferation in human cell line: A tool for arresting the cell growth
Gabrielle Dias Salton, Claudia Cilene Fernandes Correia Laurino, Nicolás Oliveira Mega, Andrés Delgado-Cañedo, Niclas Setterblad, Maryvonnick Carmagnat, Ricardo Machado Xavier, Elizabeth Cirne-Lima, Guido Lenz, João Antonio Pêgas Henriques & Jomar Pereira Laurino
Pages: 560-570
Published online: 25 Aug 2017
AbstractforDeletion of eIF2β lysine stretches creates a dominant negative that affects the translation and proliferation in human cell line: A tool for arresting the cell growth | Full Text | References | PDF (1 MB)
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Article
Macrocyclic peptides decrease c-Myc protein levels and reduce prostate cancer cell growth
Archana Mukhopadhyay, Laura E. Hanold, Hamsa Thayele Purayil, Solomon A. Gisemba, Sanjeewa N. Senadheera & Jane V. Aldrich
Pages: 571-583
Published online: 09 Aug 2017
AbstractforMacrocyclic peptides decrease c-Myc protein levels and reduce prostate cancer cell growth | Full Text | References | PDF (1.2 MB)
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Article
The novel autophagy inhibitor elaiophylin exerts antitumor activity against multiple myeloma with mutant TP53 in part through endoplasmic reticulum stress-induced apoptosis
Gaoxiang Wang, Pan Zhou, Xing Chen, Lei Zhao, Jiaqi Tan, Yang Yang, Yong Fang & Jianfeng Zhou
Pages: 584-595
Published online: 11 Aug 2017
AbstractforThe novel autophagy inhibitor elaiophylin exerts antitumor activity against multiple myeloma with mutant TP53 in part through endoplasmic reticulum stress-induced apoptosis | Full Text | References | PDF (1.5 MB) | Supplemental
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Article
Depletion of carbonic anhydrase IX abrogates hypoxia-induced overexpression of stanniocalcin-1 in triple negative breast cancer cells
Elīna Zandberga, Pawel Zayakin, Artūrs Ābols, Dārta Pūpola, Pēteris Trapencieris & Aija Linē
Pages: 596-605
Published online: 28 Jul 2017
AbstractforDepletion of carbonic anhydrase IX abrogates hypoxia-induced overexpression of stanniocalcin-1 in triple negative breast cancer cells | Full Text | References | PDF (1.1 MB)
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Article
Simultaneous targeting of ATM and Mcl-1 increases cisplatin sensitivity of cisplatin-resistant non-small cell lung cancer
Fuquan Zhang, Mingjing Shen, Li Yang, Xiaodong Yang, Ying Tsai, Peter C. Keng, Yongbing Chen, Soo Ok Lee & Yuhchyau Chen
Pages: 606-615
Published online: 13 Sep 2017
AbstractforSimultaneous targeting of ATM and Mcl-1 increases cisplatin sensitivity of cisplatin-resistant non-small cell lung cancer | Full Text | References | PDF (1 MB)
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Article
Liposomal prednisolone phosphate potentiates the antitumor activity of liposomal 5-fluorouracil in C26 murine colon carcinoma in vivo
Laura Patras, Bianca Sylvester, Lavinia Luput, Alina Sesarman, Emilia Licarete, Alina Porfire, Dana Muntean, Denise Minerva Drotar, Alexandra Doina Rusu, Andras-Laszlo Nagy, Cornel Catoi, Ioan Tomuta, Laurian Vlase, Manuela Banciu & Marcela Achim
Pages: 616-626
Published online: 12 Sep 2017
AbstractforLiposomal prednisolone phosphate potentiates the antitumor activity of liposomal 5-fluorouracil in C26 murine colon carcinoma in vivo | Full Text | References | PDF (1.3 MB)
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Article
Enhanced procoagulant activity of platelets after chemotherapy in non-small cell lung cancer
Ruishuang Ma, Yayan Bi, Junjie Kou, Jin Zhou & Jialan Shi
Pages: 627-634
Published online: 21 Sep 2017
AbstractforEnhanced procoagulant activity of platelets after chemotherapy in non-small cell lung cancer | Full Text | References | PDF (847.2 KB)
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