Cancer Biology & Therapy, Volume 19, Issue 10 (2018)

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Cancer Biology & Therapy, Volume 19, Issue 10 (2018)

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Letter to the Editor

Letter
Cabozantinib and Vandetanib in medullary thyroid carcinoma: mitochondrial function and its potential as a therapeutic target towards novel strategies to design anti-CSCs drugs
Ekaterini Christina Tampaki, Athanasios Tampakis, Raoul Droeser, Efstratios Patsouris & Gregory Kouraklis
Pages: 847-849
Published online: 17 Aug 2018
First Page PreviewforCabozantinib and Vandetanib in medullary thyroid carcinoma: mitochondrial function and its potential as a therapeutic target towards novel strategies to design anti-CSCs drugs | Full Text | References | PDF (320.4 KB)
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Review

Review
HPV epigenetic mechanisms related to Oropharyngeal and Cervix cancers
Marina Di Domenico, Giancarlo Giovane, Soumaya Kouidhi, Rosamaria Iorio, Maurizio Romano, Francesco De Francesco, Antonia Feola, Camilla Siciliano, Luigi Califano & Antonio Giordano
Pages: 850-857
Published online: 14 May 2018
AbstractforHPV epigenetic mechanisms related to Oropharyngeal and Cervix cancers | Full Text | References | PDF (524.4 KB)
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Review
Breast cancer lung metastasis: Molecular biology and therapeutic implications
Liting Jin, Bingchen Han, Emily Siegel, Yukun Cui, Armando Giuliano & Xiaojiang Cui
Pages: 858-868
Published online: 30 Apr 2018
AbstractforBreast cancer lung metastasis: Molecular biology and therapeutic implications | Full Text | References | PDF (527.9 KB)
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Journal Club

Article
Molecular drivers of metastatic castrate-resistant prostate cancer: New roads to resistance
Phoebe A. Huang, Douglas K. Price & William D. Figg
Pages: 869-870
Published online: 14 May 2018
AbstractforMolecular drivers of metastatic castrate-resistant prostate cancer: New roads to resistance | Full Text | References | PDF (305.9 KB)
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Bedside to Bench Report

Report
Unusually long-term responses to vemurafenib in BRAF V600E mutated colon and thyroid cancers followed by the development of rare RAS activating mutations
Tali Ofir Dovrat, Ethan Sokol, Garrett Frampton, Eliya Shachar, Sharon Pelles, Ravit Geva & Ido Wolf
Pages: 871-874
Published online: 23 Jul 2018
AbstractforUnusually long-term responses to vemurafenib in BRAF V600E mutated colon and thyroid cancers followed by the development of rare RAS activating mutations | Full Text | References | PDF (517.7 KB)
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Report
Early brain metastasis of advanced gastric cancer with a pathological complete response to neoadjuvant chemotherapy followed by surgery: A case report and literature review
Hui Luo, Liangqun Peng, Nan Wang, Jiangong Zhang, Xiaoli Zheng, Yanan Sun, Chengcheng Fan & Hong Ge
Pages: 875-878
Published online: 30 Apr 2018
AbstractforEarly brain metastasis of advanced gastric cancer with a pathological complete response to neoadjuvant chemotherapy followed by surgery: A case report and literature review | Full Text | References | PDF (561 KB)
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Clinical Study

Case Report
Clinical and molecular predictors of long-term response in HER2 positive metastatic breast cancer patients
Claudia Omarini, Stefania Bettelli, Cecilia Caprera, Samantha Manfredini, Federica Caggia, Giorgia Guaitoli, Luca Moscetti, Angela Toss, Laura Cortesi, Shaniko Kaleci, Antonino Maiorana, Stefano Cascinu, Pier Franco Conte & Federico Piacentini
Pages: 879-886
Published online: 01 Aug 2018
AbstractforClinical and molecular predictors of long-term response in HER2 positive metastatic breast cancer patients | Full Text | References | PDF (1.2 MB)
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Case Report
Pancreatic and bile duct cancer circulating tumor cells (CTC) form immune-resistant multi-cell type clusters in the portal venous circulation
J Pablo Arnoletti, Na’im Fanaian, Joseph Reza, Ryan Sause, Alvin JO Almodovar, Milan Srivastava, Swati Patel, Paula P Veldhuis, Elizabeth Griffith, Yai-Ping Shao, Xiang Zhu & Sally A Litherland
Pages: 887-897
Published online: 01 Aug 2018
AbstractforPancreatic and bile duct cancer circulating tumor cells (CTC) form immune-resistant multi-cell type clusters in the portal venous circulation | Full Text | References | PDF (1.7 MB)
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Research Paper

Article
Mutational landscape and clonal diversity of pulmonary adenoid cystic carcinoma
Min Li, Bing-Rong Zhao, Shi-Qing Liu, Jian An, Peng-Bo Deng, Han Han-Zhang, Jun-Yi Ye, Xin-Ru Mao, Shao-Kun Chuai & Cheng-Ping Hu
Pages: 898-903
Published online: 01 Aug 2018
AbstractforMutational landscape and clonal diversity of pulmonary adenoid cystic carcinoma | Full Text | References | PDF (1.3 MB)
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Article
A fragment of SPARC reflecting increased collagen affinity shows pathological relevance in lung cancer – implications of a new collagen chaperone function of SPARC
S.N. Kehlet, T. Manon-Jensen, S. Sun, S. Brix, D.J. Leeming, M. A. Karsdal & N. Willumsen
Pages: 904-912
Published online: 01 Aug 2018
AbstractforA fragment of SPARC reflecting increased collagen affinity shows pathological relevance in lung cancer – implications of a new collagen chaperone function of SPARC | Full Text | References | PDF (1 MB)
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Article
Metastatic colon adenocarcinoma has a significantly elevated expression of IL-10 compared with primary colon adenocarcinoma tumors
Michelle H. Townsend, Abigail M. Felsted, Stephen R. Piccolo, Richard A. Robison & Kim L. O'Neill
Pages: 913-920
Published online: 10 May 2018
AbstractforMetastatic colon adenocarcinoma has a significantly elevated expression of IL-10 compared with primary colon adenocarcinoma tumors | Full Text | References | PDF (1.2 MB)
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Article
Induction of anaplastic lymphoma kinase (ALK) as a novel mechanism of EGFR inhibitor resistance in head and neck squamous cell carcinoma patient-derived models
Xiaoming Ouyang, Ashley Barling, Aletha Lesch, Jeffrey W. Tyner, Gabrielle Choonoo, Christina Zheng, Sophia Jeng, Toni M. West, Daniel Clayburgh, Sara A. Courtneidge, Shannon K. McWeeney & Molly Kulesz-Martin
Pages: 921-933
Published online: 17 Aug 2018
AbstractforInduction of anaplastic lymphoma kinase (ALK) as a novel mechanism of EGFR inhibitor resistance in head and neck squamous cell carcinoma patient-derived models | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Liquid biopsy of bile for the molecular diagnosis of gallbladder cancer
Hideaki Kinugasa, Kazuhiro Nouso, Soichiro Ako, Chihiro Dohi, Hiroshi Matsushita, Kazuyuki Matsumoto, Hironari Kato & Hiroyuki Okada
Pages: 934-938
Published online: 04 May 2018
AbstractforLiquid biopsy of bile for the molecular diagnosis of gallbladder cancer | Full Text | References | PDF (293.9 KB)
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Article
Comparison of EpCAMhighCD44+ cancer stem cells with EpCAMhighCD44− tumor cells in colon cancer by single-cell sequencing
Mingshan Liu, Jiabo Di, Yang Liu, Zhe Su, Beihai Jiang, Zaozao Wang & Xiangqian Su
Pages: 939-947
Published online: 12 Apr 2018
AbstractforComparison of EpCAMhighCD44+ cancer stem cells with EpCAMhighCD44− tumor cells in colon cancer by single-cell sequencing | Full Text | References | PDF (1.4 MB)
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Errata

Correction
Erratum
Page: 948
Published online: 20 Jun 2018
CitationforErratum | Full Text | PDF (241.4 KB)
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