OncoImmunology, Volume 3, Issue 1 (2014)

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OncoImmunology, Volume 3, Issue 1 (2014)

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Editorial

Editorial
Intratumoral checkpoint subversion as a strategy for minimizing adverse effects
Harvesting the power of TILs without harvesting TILs
Leah Alabanza, Sacha Gnjatic, Nina Bhardwaj & Joshua Brody
Article: e27580
Published online: 03 Jan 2014
First Page PreviewforIntratumoral checkpoint subversion as a strategy for minimizing adverse effects | Full Text | References | PDF (521.9 KB)
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Original Research

Article
Sustained CD4+ T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide
Susannah Ellsworth, Ani Balmanoukian, Ferdynand Kos, Christopher J Nirschl, Thomas R Nirschl, Stuart A Grossman, Leo Luznik & Charles G Drake
Article: e27357
Published online: 03 Jan 2014
AbstractforSustained CD4+ T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide | Full Text | References | PDF (900.4 KB) | Supplemental
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Author's View

Membrane-bound KIT ligand-targeting DNA vaccination inhibits mammary tumor growth
Patrizia Dentelli, Federica Cavallo & Maria Felice Brizzi
Article: e27259
Published online: 01 Jan 2014
AbstractforMembrane-bound KIT ligand-targeting DNA vaccination inhibits mammary tumor growth | Full Text | References | PDF (498.3 KB)
  • 433 Views
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Original Research

Article
A novel minigene scaffold for therapeutic cancer vaccines
Luigi Aurisicchio, Arthur Fridman, Ansuman Bagchi, Elisa Scarselli, Nicola La Monica & Gennaro Ciliberto
Article: e27529
Published online: 16 Jan 2014
AbstractforA novel minigene scaffold for therapeutic cancer vaccines | Full Text | References | PDF (670.1 KB)
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Open Access
Article
Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo
Linda C Sandin, Fredrik Eriksson, Peter Ellmark, Angelica SI Loskog, Thomas H Tötterman & Sara M Mangsbo
Article: e27614
Published online: 16 Jan 2014
AbstractforLocal CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo | Full Text | References | PDF (774.8 KB)
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Brief Report

Brief Report
Genetic variants of IgG1 antibodies and FcγRIIIa receptors influence the magnitude of antibody-dependent cell-mediated cytotoxicity against prostate cancer cells
Janardan P Pandey & Aryan M Namboodiri
Article: e27317
Published online: 01 Jan 2014
AbstractforGenetic variants of IgG1 antibodies and FcγRIIIa receptors influence the magnitude of antibody-dependent cell-mediated cytotoxicity against prostate cancer cells | Full Text | References | PDF (184.5 KB)
  • 791 Views
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Review

Review Article
Trial Watch
Tumor-targeting monoclonal antibodies in cancer therapy
Erika Vacchelli, Fernando Aranda, Alexander Eggermont, Jérôme Galon, Catherine Sautès-Fridman, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi
Article: e27048
Published online: 01 Jan 2014
AbstractforTrial Watch | Full Text | References | PDF (658.3 KB)
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Review Article
Harnessing the immune system to provide long-term survival in patients with melanoma and other solid tumors
Alexander Eggermont, Caroline Robert, Jean Charles Soria & Laurence Zitvogel
Article: e27560
Published online: 03 Jan 2014
AbstractforHarnessing the immune system to provide long-term survival in patients with melanoma and other solid tumors | Full Text | References | PDF (255 KB)
  • 1041 Views
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Review Article
Implementing combinatorial immunotherapeutic regimens against cancer
The concept of immunological conditioning
Dominik Wolf, Annkristin Heine & Peter Brossart
Article: e27588
Published online: 03 Jan 2014
AbstractforImplementing combinatorial immunotherapeutic regimens against cancer | Full Text | References | PDF (591.3 KB)
  • 829 Views
  • 13 CrossRef citations
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Open Access
Review Article
Obesity and renal cancer
Role of adipokines in the tumor-immune system conflict
Asma Gati, Soumaya Kouidhi, Raja Marrakchi, Amel El Gaaied, Nadia Kourda, Amine Derouiche, Mohamed Chebil, Anne Caignard & Aurélie Perier
Article: e27810
Published online: 16 Jan 2014
AbstractforObesity and renal cancer | Full Text | References | PDF (1.1 MB)
  • 1974 Views
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Review Article
γδ T cells for cancer immunotherapy
A systematic review of clinical trials
Jonathan PH Fisher, Jennifer Heuijerjans, Mengyong Yan, Kenth Gustafsson & John Anderson
Article: e27572
Published online: 17 Jan 2014
Abstractforγδ T cells for cancer immunotherapy | Full Text | References | PDF (420.3 KB) | Supplemental
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Point of View

Exomics and immunogenics
Bridging mutational load and immune checkpoints efficacy
Stéphane Champiat, Charles Ferté, Sophie Lebel-Binay, Alexander Eggermont & Jean Charles Soria
Article: e27817
Published online: 16 Jan 2014
AbstractforExomics and immunogenics | Full Text | References | PDF (431.6 KB)
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Author's View

Combining NK cells and mAb9.2.27 to combat NG2-dependent and anti-inflammatory signals in glioblastoma
Justyna Kmiecik, Andrea Gras Navarro, Aurelie Poli, Jesús Planagumà Planagumà, Jacques Zimmer & Martha Chekenya
Article: e27185
Published online: 01 Jan 2014
AbstractforCombining NK cells and mAb9.2.27 to combat NG2-dependent and anti-inflammatory signals in glioblastoma | Full Text | References | PDF (445.7 KB)
  • 1036 Views
  • 23 CrossRef citations
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Open Access
Immunovirotherapy for the treatment of glioblastoma
Tooba A Cheema, Peter E Fecci, Jianfang Ning & Samuel D Rabkin
Article: e27218
Published online: 01 Jan 2014
AbstractforImmunovirotherapy for the treatment of glioblastoma | Full Text | References | PDF (254.8 KB)
  • 906 Views
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Open Access
Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy
Florian Wimmers, Erik HJG Aarntzen, Gerty Schreibelt, Joannes FM Jacobs, Cornelis JA Punt, Carl G Figdor & I Jolanda M de Vries
Article: e27219
Published online: 01 Jan 2014
AbstractforEarly predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy | Full Text | References | PDF (311.5 KB)
  • 565 Views
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Open Access
An immunotherapeutic intervention against tumor progression
Targeting a driver of the epithelial-to-mesenchymal transition
Claudia Palena, Romaine I Fernando & Duane H Hamilton
Article: e27220
Published online: 01 Jan 2014
AbstractforAn immunotherapeutic intervention against tumor progression | Full Text | References | PDF (368.4 KB)
  • 606 Views
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Open Access
The immune response in HPV+ oropharyngeal cancer
Emma V King, Christian H Ottensmeier & Gareth J Thomas
Article: e27254
Published online: 01 Jan 2014
AbstractforThe immune response in HPV+ oropharyngeal cancer | Full Text | References | PDF (535.7 KB)
  • 919 Views
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Open Access
Targeting human CD27 with an agonist antibody stimulates T-cell activation and antitumor immunity
Lawrence J Thomas, Li-Zhen He, Henry Marsh & Tibor Keler
Article: e27255
Published online: 01 Jan 2014
AbstractforTargeting human CD27 with an agonist antibody stimulates T-cell activation and antitumor immunity | Full Text | References | PDF (266 KB)
  • 1156 Views
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Immunotherapeutic implications of the immunophenotype of pediatric brain tumors
Andrea M Griesinger, Andrew M Donson & Nicholas K Foreman
Article: e27256
Published online: 01 Jan 2014
AbstractforImmunotherapeutic implications of the immunophenotype of pediatric brain tumors | Full Text | References | PDF (269.1 KB)
  • 695 Views
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Open Access
Human papillomavirus (HPV) deregulation of Toll-like receptor 9
Uzma Hasan
Article: e27257
Published online: 01 Jan 2014
AbstractforHuman papillomavirus (HPV) deregulation of Toll-like receptor 9 | Full Text | References | PDF (267.5 KB)
  • 775 Views
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Open Access
A novel system for cloning human TCRs
Cutting short the way to TCR-based anticancer therapy
Eiji Kobayashi, Hiroyuki Kishi & Atsushi Muraguchi
Article: e27258
Published online: 01 Jan 2014
AbstractforA novel system for cloning human TCRs | Full Text | References | PDF (262.3 KB)
  • 799 Views
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Anti-HER2/Neu passive-aggressive immunotherapy
Eric D Mortenson & Yang-Xin Fu
Article: e27296
Published online: 01 Jan 2014
AbstractforAnti-HER2/Neu passive-aggressive immunotherapy | Full Text | References | PDF (291.7 KB)
  • 588 Views
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Invadopodia formation in blood clots
Not so SLUGgish after all
Lynn M Knowles, Jodi K Maranchie & Jan Pilch
Article: e27338
Published online: 01 Jan 2014
AbstractforInvadopodia formation in blood clots | Full Text | References | PDF (227.3 KB)
  • 455 Views
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Chemotherapeutic targeting of myeloid-derived suppressor cells
Darya Alizadeh, Emmanuel Katsanis & Nicolas Larmonier
Article: e27359
Published online: 01 Jan 2014
AbstractforChemotherapeutic targeting of myeloid-derived suppressor cells | Full Text | References | PDF (305.3 KB)
  • 512 Views
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Polyamine blockade promotes antitumor immunity
Candace S Hayes, Mark R Burns & Susan K Gilmour
Article: e27360
Published online: 01 Jan 2014
AbstractforPolyamine blockade promotes antitumor immunity | Full Text | References | PDF (295.8 KB)
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The dual targeting of immunosuppressive cells and oxidants promotes effector and memory T-cell functions against lung cancer
Anandi Sawant, Cara C Schafer, Selvarangan Ponnazhagan & Jessy S Deshane
Article: e27401
Published online: 01 Jan 2014
AbstractforThe dual targeting of immunosuppressive cells and oxidants promotes effector and memory T-cell functions against lung cancer | Full Text | References | PDF (363.9 KB)
  • 449 Views
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Melanoma hijacks plasmacytoid dendritic cells to promote its own progression
Caroline Aspord, Marie-Therese Leccia, Julie Charles & Joel Plumas
Article: e27402
Published online: 01 Jan 2014
AbstractforMelanoma hijacks plasmacytoid dendritic cells to promote its own progression | Full Text | References | PDF (433.1 KB)
  • 794 Views
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Tumor-infiltrating lymphocytes favor the response to chemoradiotherapy of head and neck cancer
Panagiotis Balermpas, Franz Rödel, Christian Weiss, Claus Rödel & Emmanouil Fokas
Article: e27403
Published online: 01 Jan 2014
AbstractforTumor-infiltrating lymphocytes favor the response to chemoradiotherapy of head and neck cancer | Full Text | References | PDF (433.2 KB)
  • 959 Views
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The anticancer effects of HDAC inhibitors require the immune system
Alison C West, Mark J Smyth & Ricky W Johnstone
Article: e27414
Published online: 01 Jan 2014
AbstractforThe anticancer effects of HDAC inhibitors require the immune system | Full Text | References | PDF (292.6 KB)
  • 1448 Views
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Open Access
Why should we need the gut microbiota to respond to cancer therapies?
Sophie Viaud, Romain Daillère, Takahiro Yamazaki, Patricia Lepage, Ivo Boneca, Romina Goldszmid, Giorgio Trinchieri & Laurence Zitvogel
Article: e27574
Published online: 17 Jan 2014
AbstractforWhy should we need the gut microbiota to respond to cancer therapies? | Full Text | References | PDF (384.3 KB)
  • 1337 Views
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