Nucleosides, Nucleotides & Nucleic Acids, Volume 27, Issue 6-7 (2008)

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Nucleosides, Nucleotides & Nucleic Acids, Volume 27, Issue 6-7 (2008)

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Proceedings of the 12th International Symposium on Purine and Pyrimidine Metabolism in Man (PP07)

Article
PP07: New Approaches, New Knowledge, New Challenges in Human Purine and Pyrimidine Metabolism
Michael A. Becker & Richard L. Sabina
Pages: 547-553
Published online: 03 Jul 2008
First Page PreviewforPP07: New Approaches, New Knowledge, New Challenges in Human Purine and Pyrimidine Metabolism | Full Text | PDF (51.3 KB)
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Article
In Memoriam: J. Edwin Seegmiller, M.D. (1920–2006)
Michael A. Becker, Theodore Friedmann, Kari O. Raivio, Michael S. Hershfield & George Nuki
Pages: 554-556
Published online: 03 Jul 2008
First Page PreviewforIn Memoriam: J. Edwin Seegmiller, M.D. (1920–2006) | Full Text | PDF (215.9 KB)
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Article
In Memoriam: Albert van Gennip (1943–2007)
Andre van Kuilenburg & Ronney de Abreu
Pages: 557-558
Published online: 03 Jul 2008
CitationforIn Memoriam: Albert van Gennip (1943–2007) | Full Text | PDF (181.9 KB)
  • 31 Views
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Article
Lesch-Nyhan Disease
W. L. Nyhan
Pages: 559-563
Published online: 03 Jul 2008
AbstractforLesch-Nyhan Disease | Full Text | References | PDF (80.9 KB)
  • 396 Views
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Article
The Diagnosis Of HPRT Deficiency in the 21St Century
R. J. Torres & J. G. Puig
Pages: 564-569
Published online: 03 Jul 2008
AbstractforThe Diagnosis Of HPRT Deficiency in the 21St Century | Full Text | References | PDF (53.5 KB)
  • 99 Views
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Article
Molecular Analysis of Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) Deficiencies: Novel Mutations and the Spectrum of Japanese Mutations
Yasukazu Yamada, Noriko Nomura, Kenichro Yamada, Nobuaki Wakamatsu, Kiyoko Kaneko & Shin Fujimori
Pages: 570-574
Published online: 03 Jul 2008
AbstractforMolecular Analysis of Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) Deficiencies: Novel Mutations and the Spectrum of Japanese Mutations | Full Text | References | PDF (61.3 KB)
  • 80 Views
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Article
Urinary Guanidinoacetate and Creatine Levels in Patients with HPRT Deficiency
A. Verdú, R. J. Torres, B. Merinero & J. G. Puig
Pages: 575-577
Published online: 03 Jul 2008
AbstractforUrinary Guanidinoacetate and Creatine Levels in Patients with HPRT Deficiency | Full Text | References | PDF (45.1 KB)
  • 52 Views
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Article
Urate Transport Across the Apical Membrane of Renal Proximal Tubules
Hitoshi Endou & Naohiko Anzai
Pages: 578-584
Published online: 03 Jul 2008
AbstractforUrate Transport Across the Apical Membrane of Renal Proximal Tubules | Full Text | References | PDF (188.4 KB)
  • 219 Views
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Article
Determinants of the Clinical Outcomes of Gout During the First Year of Urate-Lowering Therapy
Michael A. Becker, Patricia A. MacDonald, Barbara J. Hunt, Christopher Lademacher & Nancy Joseph-Ridge
Pages: 585-591
Published online: 03 Jul 2008
AbstractforDeterminants of the Clinical Outcomes of Gout During the First Year of Urate-Lowering Therapy | Full Text | References | PDF (90.4 KB)
  • 458 Views
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Article
Asymptomatic Hyperuricemia: Impact of Ultrasonography
J. G. Puig, E. de Miguel, M. C. Castillo, A. López Rocha, M. A. Martínez & R. J. Torres
Pages: 592-595
Published online: 03 Jul 2008
AbstractforAsymptomatic Hyperuricemia: Impact of Ultrasonography | Full Text | References | PDF (376.8 KB)
  • 391 Views
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Article
Production and Characterization of Transgenic Mice Harboring Mutant Human UMOD Gene
Yuichi Takiue, Makoto Hosoyamada, Takuya Yokoo, Masaki Kimura, Manami Ochiai, Kiyoko Kaneko, Kimiyoshi Ichida, Tatsuo Hosoya & Toshiaki Shibasaki
Pages: 596-600
Published online: 03 Jul 2008
AbstractforProduction and Characterization of Transgenic Mice Harboring Mutant Human UMOD Gene | Full Text | References | PDF (417 KB)
  • 95 Views
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Article
Effects of Allopurinol on Beer-Induced Increases in Plasma Concentrations of Purine Bases and Uridine
Taku Inokuchi, Tuneyoshi Ka, Asako Yamamoto, Sumio Takahashi, Zenta Tsutsumi, Yuji Moriwaki & Tetsuya Yamamoto
Pages: 601-603
Published online: 03 Jul 2008
AbstractforEffects of Allopurinol on Beer-Induced Increases in Plasma Concentrations of Purine Bases and Uridine | Full Text | References | PDF (39.8 KB)
  • 68 Views
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Article
An Unusual Patient with Hypothyroidism, Tophaceous Gout, and Marked Joint Destruction
F. Montoya, R. J. Torres, J. M. Fraile & J. G. Puig
Pages: 604-607
Published online: 03 Jul 2008
AbstractforAn Unusual Patient with Hypothyroidism, Tophaceous Gout, and Marked Joint Destruction | Full Text | References | PDF (393.6 KB)
  • 75 Views
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Article
Uric Acid: The Oxidant-Antioxidant Paradox
Yuri Y. Sautin & Richard J. Johnson
Pages: 608-619
Published online: 03 Jul 2008
AbstractforUric Acid: The Oxidant-Antioxidant Paradox | Full Text | References | PDF (3.1 MB)
  • 2204 Views
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Article
Serum Urate, Metabolic Syndrome, and Cardiovascular Risk Factors. A Population-Based Study
J. G. Puig, M. A. Martínez, M. Mora, J. M. Fraile, F. Montoya & R. J. Torres
Pages: 620-623
Published online: 03 Jul 2008
AbstractforSerum Urate, Metabolic Syndrome, and Cardiovascular Risk Factors. A Population-Based Study | Full Text | References | PDF (66.4 KB)
  • 92 Views
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Article
Antioxidant Status and Purine Bases in Carotid Artery Plaque
I. Ciari, L. Terzuoli, B. Porcelli, M. G. Coppola & E. Marinello
Pages: 624-627
Published online: 03 Jul 2008
AbstractforAntioxidant Status and Purine Bases in Carotid Artery Plaque | Full Text | References | PDF (55.3 KB)
  • 48 Views
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Article
Purine Contents of Soybean-Derived Foods and Selected Japanese Vegetables and Mushrooms
K. Kaneko, Y. Kudo, T. Yamanobe, K. Mawatari, M. Yasuda, K. Nakagomi & S. Fujimori
Pages: 628-630
Published online: 03 Jul 2008
AbstractforPurine Contents of Soybean-Derived Foods and Selected Japanese Vegetables and Mushrooms | Full Text | References | PDF (45.3 KB)
  • 279 Views
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Article
Effect of Acarbose on the Increased Plasma Concentration of Uric Acid Induced by Sucrose Ingestion
Y. Moriwaki, T. Inokuchi, T. Ka, A. Yamamoto, Z. Tsutsumi, S. Takahashi & T. Yamamoto
Pages: 631-633
Published online: 03 Jul 2008
AbstractforEffect of Acarbose on the Increased Plasma Concentration of Uric Acid Induced by Sucrose Ingestion | Full Text | References | PDF (45.4 KB)
  • 66 Views
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Article
Fludarabine Induces Differential Expression of Proteins in Human Leukemia and Lymphoma Cells
S. Henrich, S. Gez, B. Crossett, S. P. Mulligan & R. I. Christopherson
Pages: 634-640
Published online: 03 Jul 2008
AbstractforFludarabine Induces Differential Expression of Proteins in Human Leukemia and Lymphoma Cells | Full Text | References | PDF (938.8 KB)
  • 56 Views
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Article
Application of Metabolomic Principles to Disorders of Nucleotide Metabolism Reveals New Metabolic Perturbations
Floyd F. Snyder, Robert J. Carter, Ernest Fung, Stephen D. Hodges & Kevin B. Mantik
Pages: 641-647
Published online: 03 Jul 2008
AbstractforApplication of Metabolomic Principles to Disorders of Nucleotide Metabolism Reveals New Metabolic Perturbations | Full Text | References | PDF (2.3 MB)
  • 86 Views
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Article
Unusual Presentation of Kelley-Seegmiller Syndrome
I. Sebesta, B. StibÅrková, L. Dvorakova, M. Hrebicek, J. Minks, L. Stolnaja, Z. Vernerova & I. Rychlik
Pages: 648-655
Published online: 03 Jul 2008
AbstractforUnusual Presentation of Kelley-Seegmiller Syndrome | Full Text | References | PDF (172.7 KB)
  • 168 Views
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Article
ITPase Activity in Dry Blood Spots is Comparable with That in Fresh Erythrocytes
J. Tomkova, D. Friedecky, P. Vyskocilova & T. Adam
Pages: 656-660
Published online: 03 Jul 2008
AbstractforITPase Activity in Dry Blood Spots is Comparable with That in Fresh Erythrocytes | Full Text | References | PDF (181.1 KB)
  • 46 Views
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Article
Fatal Myelotoxicity After Azathioprine Treatment
O. Slanař, P. Chalupná, A. Novotný, M. Bortlík, Z. Krška & M. Lukáš
Pages: 661-665
Published online: 03 Jul 2008
AbstractforFatal Myelotoxicity After Azathioprine Treatment | Full Text | References | PDF (55.9 KB)
  • 109 Views
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Article
Neurotrophic Effects of Extracellular Guanosine
Michel Rathbone, Lara Pilutti, Francesco Caciagli & Shucui Jiang
Pages: 666-672
Published online: 03 Jul 2008
AbstractforNeurotrophic Effects of Extracellular Guanosine | Full Text | References | PDF (66.9 KB)
  • 294 Views
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Article
Metabolism and Distribution of Guanosine Given Intraperitoneally: Implications for Spinal Cord Injury
Shucui Jiang, Gemma Fischione, Patricia Guiliani, Silvia Romano, Francesco Caciagli & Patrizia DiIorio
Pages: 673-680
Published online: 03 Jul 2008
AbstractforMetabolism and Distribution of Guanosine Given Intraperitoneally: Implications for Spinal Cord Injury | Full Text | References | PDF (556.6 KB)
  • 100 Views
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Article
The Role of Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase in Tumor Behavior
I. V. Bijnsdorp, M. de Bruin, A. C. Laan, M. Fukushima & G. J. Peters
Pages: 681-691
Published online: 03 Jul 2008
AbstractforThe Role of Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase in Tumor Behavior | Full Text | References | PDF (306.4 KB)
  • 270 Views
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Article
Pharmacokinetics of 5-Fluorouracil in Patients Heterozygous for the IVS14+1G > A Mutation in the Dihydropyrimidine Dehydrogenase Gene
A. B. P. van Kuilenburg, J. G. Maring, A. Schalhorn, C. Terborg, H. Schmalenberg, D. Behnke, W. Schwabe, K. Jabschinsky & P. Hausler
Pages: 692-698
Published online: 03 Jul 2008
AbstractforPharmacokinetics of 5-Fluorouracil in Patients Heterozygous for the IVS14+1G > A Mutation in the Dihydropyrimidine Dehydrogenase Gene | Full Text | References | PDF (110.3 KB)
  • 176 Views
  • 20 CrossRef citations
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Article
Trifluorothymidine Induces Cell Death Independently of p53
I. V. Bijnsdorp, F. A. Kruyt, M. Fukushima & G. J. Peters
Pages: 699-703
Published online: 03 Jul 2008
AbstractforTrifluorothymidine Induces Cell Death Independently of p53 | Full Text | References | PDF (192.3 KB)
  • 97 Views
  • 6 CrossRef citations
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Article
Guanine Nucleotide Depletion Mediates Translocation of Nucleolar Proteins, Including RNA Helicase A (DHX-9)
Min Huang & Beverly S. Mitchell
Pages: 704-711
Published online: 03 Jul 2008
AbstractforGuanine Nucleotide Depletion Mediates Translocation of Nucleolar Proteins, Including RNA Helicase A (DHX-9) | Full Text | References | PDF (198.8 KB)
  • 241 Views
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Article
RNAi Depletion of Deoxycytidine and Deoxyguanosine Kinase in Human Leukemic CEM Cells
Anna Fyrberg, Freidoun Albertioni & Kourosh Lotfi
Pages: 712-719
Published online: 03 Jul 2008
AbstractforRNAi Depletion of Deoxycytidine and Deoxyguanosine Kinase in Human Leukemic CEM Cells | Full Text | References | PDF (464.2 KB)
  • 66 Views
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Article
Correlation Between Cytidine Deaminase Genotype and Gemcitabine Deamination in Blood Samples
E. Giovannetti, A. C. Laan, E. Vasile, C. Tibaldi, S. Nannizzi, S. Ricciardi, A. Falcone, R. Danesi & G. J. Peters
Pages: 720-725
Published online: 03 Jul 2008
AbstractforCorrelation Between Cytidine Deaminase Genotype and Gemcitabine Deamination in Blood Samples | Full Text | References | PDF (72.7 KB)
  • 281 Views
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Article
Altered Dihydropyrimidine Dehydrogenase Activity Associated with Mild Toxicity in Patients Treated with 5-Fluorouracil Containing Chemotherapy
André B. P. van Kuilenburg, Heinz-Josef Klumpen, Anneke M. Westermann, Lida Zoetekouw, Piet J. M. Bakker, Henk-Jan Guchelaar & Dick J. Richel
Pages: 726-732
Published online: 03 Jul 2008
AbstractforAltered Dihydropyrimidine Dehydrogenase Activity Associated with Mild Toxicity in Patients Treated with 5-Fluorouracil Containing Chemotherapy | Full Text | References | PDF (369.9 KB)
  • 85 Views
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Article
Selective Protection by Uridine of Growth Inhibition by 5-Fluorouracil (5FU) Mediated by 5FU Incorporation into RNA, But Not the Thymidylate Synthase Mediated Growth Inhibition by 5FU-Leucovorin
G. Codacci-Pisanelli, P. Noordhuis, C. L. van der Wilt & G. J. Peters
Pages: 733-739
Published online: 03 Jul 2008
AbstractforSelective Protection by Uridine of Growth Inhibition by 5-Fluorouracil (5FU) Mediated by 5FU Incorporation into RNA, But Not the Thymidylate Synthase Mediated Growth Inhibition by 5FU-Leucovorin | Full Text | References | PDF (133.3 KB)
  • 113 Views
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Article
Functional Inactivity and Mutations of p53 Differentially Affect Sensitivity to 5-Fluorouracil and Antifolate Inhibitors of Thymidylate Synthase (TS) by Altering TS Levels in Colorectal Cancer Cells
E. Giovannetti, H. H. J. Backus, D. Wouters & G. J. Peters
Pages: 740-745
Published online: 03 Jul 2008
AbstractforFunctional Inactivity and Mutations of p53 Differentially Affect Sensitivity to 5-Fluorouracil and Antifolate Inhibitors of Thymidylate Synthase (TS) by Altering TS Levels in Colorectal Cancer Cells | Full Text | References | PDF (232.9 KB)
  • 63 Views
  • 4 CrossRef citations
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Article
Reduced Levels of Mitochondrial DNA Increases the Toxicity of 9-ß-D-Arabinofuranosylguanine (araG)
M. Bjerke, J. Balzarini & A. Karlsson
Pages: 746-749
Published online: 03 Jul 2008
AbstractforReduced Levels of Mitochondrial DNA Increases the Toxicity of 9-ß-D-Arabinofuranosylguanine (araG) | Full Text | References | PDF (55.8 KB)
  • 39 Views
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Article
Adenosine Kinase Gene Expression in Human Colorectal Cancer
S. Giglioni, R. Leoncini, E. Aceto, A. Chessa, S. Civitelli, A. Bernini, G. Tanzini, F. Carraro, A. Pucci & D. Vannoni
Pages: 750-754
Published online: 03 Jul 2008
AbstractforAdenosine Kinase Gene Expression in Human Colorectal Cancer | Full Text | References | PDF (110.9 KB)
  • 165 Views
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Article
Regulation of Leukocyte Migration Across Endothelial Barriers by ECTO-5′-Nucleotidase-Generated Adenosine
Linda F. Thompson, Masahide Takedachi, Yukihiko Ebisuno, Toshiyuki Tanaka, Masayuki Miyasaka, Jeffery H. Mills & Margaret S. Bynoe
Pages: 755-760
Published online: 03 Jul 2008
AbstractforRegulation of Leukocyte Migration Across Endothelial Barriers by ECTO-5′-Nucleotidase-Generated Adenosine | Full Text | References | PDF (98.9 KB)
  • 77 Views
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Article
Decreased Ecto-Ntpdase1/Cd39 Activity Leads to Desensitization of P2 Purinoceptors Regulating Tonus of Corpora Cavernosa in Impotent Men with Endothelial Dysfunction
M. Faria, T. Magalhães-Cardoso, J.-M. Lafuente-de-Carvalho & P. Correia-de Sá
Pages: 761-768
Published online: 03 Jul 2008
AbstractforDecreased Ecto-Ntpdase1/Cd39 Activity Leads to Desensitization of P2 Purinoceptors Regulating Tonus of Corpora Cavernosa in Impotent Men with Endothelial Dysfunction | Full Text | References | PDF (183.7 KB)
  • 78 Views
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Article
Physiological and Pharmacological Roles of Nucleoside Transporter Proteins
Míriam Molina-Arcas, Laia Trigueros-Motos, F. Javier Casado & Marçal Pastor-Anglada
Pages: 769-778
Published online: 03 Jul 2008
AbstractforPhysiological and Pharmacological Roles of Nucleoside Transporter Proteins | Full Text | References | PDF (78.3 KB)
  • 738 Views
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Article
Imatinib-Resistant CML Cells Have Low ENT Activity But Maintain Sensitivity to Gemcitabine
Andrea V. Leisewitz, Eric I. Zimmerman, Shannon Z. Jones, Jing Yang & Lee M. Graves
Pages: 779-786
Published online: 03 Jul 2008
AbstractforImatinib-Resistant CML Cells Have Low ENT Activity But Maintain Sensitivity to Gemcitabine | Full Text | References | PDF (196.8 KB)
  • 81 Views
  • 9 CrossRef citations
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Article
Immunocytochemical Detection of hENT1 and hCNT1 in Normal Tissues, Lung Cancer Cell Lines, and NSCLC Patient Samples
I. Hubeek, E. Giovannetti, A. J. F. Broekhuizen, M. Pastor-Anglada, G. J. L. Kaspers & G. J. Peters
Pages: 787-793
Published online: 03 Jul 2008
AbstractforImmunocytochemical Detection of hENT1 and hCNT1 in Normal Tissues, Lung Cancer Cell Lines, and NSCLC Patient Samples | Full Text | References | PDF (119.5 KB)
  • 115 Views
  • 7 CrossRef citations
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Article
Degradation of Pyrimidines in Saccharomyces Kluyveri: Transamination of β-Alanine
K. D. Schnackerz, G. Andersen, D. Dobritzsch & J. Piškur
Pages: 794-799
Published online: 03 Jul 2008
AbstractforDegradation of Pyrimidines in Saccharomyces Kluyveri: Transamination of β-Alanine | Full Text | References | PDF (97.9 KB)
  • 161 Views
  • 7 CrossRef citations
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Article
Molecular Mechanisms of Mitochondrial DNA Depletion Diseases Caused by Deficiencies in Enzymes in Purine and Pyrimidine Metabolism
Staffan Eriksson & Liya Wang
Pages: 800-808
Published online: 03 Jul 2008
AbstractforMolecular Mechanisms of Mitochondrial DNA Depletion Diseases Caused by Deficiencies in Enzymes in Purine and Pyrimidine Metabolism | Full Text | References | PDF (478.1 KB)
  • 261 Views
  • 24 CrossRef citations
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Article
Identification of Two Novel Mutations C79X and R235Q in the Dihydropyrimidine Dehydrogenase Gene in a Patient Presenting With Hematuria
A. B. P. van Kuilenburg, J. Meijer, D. Dobritzsch, B. Lohkamp, W. Ruitenbeek, J. Roelofsen, N. G. G. M. Abeling, M. Duran & C. Buzing
Pages: 809-815
Published online: 03 Jul 2008
AbstractforIdentification of Two Novel Mutations C79X and R235Q in the Dihydropyrimidine Dehydrogenase Gene in a Patient Presenting With Hematuria | Full Text | References | PDF (558.9 KB)
  • 92 Views
  • 4 CrossRef citations
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Article
Inhibition of Deoxynucleoside Kinases in Human Thymocytes Prevents dATP Accumulation and Induction of Apoptosis
Michelle L. Joachims, Patrick Marble, Christopher Knott-Craig, Peter Pastuszko, Michael R. Blackburn & Linda F. Thompson
Pages: 816-820
Published online: 03 Jul 2008
AbstractforInhibition of Deoxynucleoside Kinases in Human Thymocytes Prevents dATP Accumulation and Induction of Apoptosis | Full Text | References | PDF (368.2 KB)
  • 51 Views
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Article
Ecto-5′-Nucleotidase (Cd73)-Mediated Extracellular Adenosine Production Plays a Critical Role in Hepatic Fibrosis
Zhongsheng Peng, Patricia Fernandez, Tuere Wilder, Herman Yee, Luis Chiriboga, Edwin S. L. Chan & Bruce N. Cronstein
Pages: 821-824
Published online: 03 Jul 2008
AbstractforEcto-5′-Nucleotidase (Cd73)-Mediated Extracellular Adenosine Production Plays a Critical Role in Hepatic Fibrosis | Full Text | References | PDF (50.8 KB)
  • 181 Views
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Article
ß-Alanine and ß-Aminoisobutyric Acid Levels in Two Siblings With Dihydropyrimidinase Deficiency
A. B. P. van Kuilenburg, A. E. M. Stroomer, A. M. Bosch & M. Duran
Pages: 825-829
Published online: 03 Jul 2008
Abstractforß-Alanine and ß-Aminoisobutyric Acid Levels in Two Siblings With Dihydropyrimidinase Deficiency | Full Text | References | PDF (158.8 KB)
  • 96 Views
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Article
Metabolism of 4-Pyridone-3-Carboxamide-1-ß-D- Ribonucleoside Triphosphate and Its Nucleoside Precursor in the Erythrocytes
E. M. Slominska, C. Orlewska, A. Yuen, L. Osman, P. Romaszko, E. Sokolowska, H. Foks, H. A. Simmonds, M. H. Yacoub & R. T. Smolenski
Pages: 830-834
Published online: 03 Jul 2008
AbstractforMetabolism of 4-Pyridone-3-Carboxamide-1-ß-D- Ribonucleoside Triphosphate and Its Nucleoside Precursor in the Erythrocytes | Full Text | References | PDF (261.4 KB)
  • 83 Views
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Article
Polymorphisms of the TPMT Gene in the Czech Healthy Population and Patients with Inflammatory Bowel Disease
Ondřej Slanař, Martin Bortlík, Helena Buzková, Robert Donoval, Kristina Pechandová, Ivan Šebesta, Milan Lukáš & František Perlík
Pages: 835-838
Published online: 03 Jul 2008
AbstractforPolymorphisms of the TPMT Gene in the Czech Healthy Population and Patients with Inflammatory Bowel Disease | Full Text | References | PDF (52.1 KB)
  • 61 Views
  • 5 CrossRef citations
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Article
IMP Dehydrogenase-Linked Retinitis Pigmentosa
Lizbeth Hedstrom
Pages: 839-849
Published online: 03 Jul 2008
AbstractforIMP Dehydrogenase-Linked Retinitis Pigmentosa | Full Text | References | PDF (1.3 MB)
  • 198 Views
  • 11 CrossRef citations
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Article
Human Cytidine Triphosphate Synthetase 1 Interacting Proteins
M. J. Higgins, D. Loiselle, T. A. Haystead & L. M. Graves
Pages: 850-857
Published online: 03 Jul 2008
AbstractforHuman Cytidine Triphosphate Synthetase 1 Interacting Proteins | Full Text | References | PDF (763.8 KB)
  • 288 Views
  • 10 CrossRef citations
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Article
5-Bromovinyl 2′-Deoxyuridine Phosphorylation by Mitochondrial and Cytosolic Thymidine Kinase (TK2 and TK1) and Its Use in Selective Measurement of TK2 Activity in Crude Extracts
Liya Wang & Staffan Eriksson
Pages: 858-862
Published online: 03 Jul 2008
Abstractfor5-Bromovinyl 2′-Deoxyuridine Phosphorylation by Mitochondrial and Cytosolic Thymidine Kinase (TK2 and TK1) and Its Use in Selective Measurement of TK2 Activity in Crude Extracts | Full Text | References | PDF (55.4 KB)
  • 110 Views
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Article
Cytoprotective Effects of Nicotinamide Derivatives in Endothelial Cells
E. M. Slominska, A. Yuen, L. Osman, J. Gebicki, M. H. Yacoub & R. T. Smolenski
Pages: 863-866
Published online: 03 Jul 2008
AbstractforCytoprotective Effects of Nicotinamide Derivatives in Endothelial Cells | Full Text | References | PDF (177.2 KB)
  • 151 Views
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Article
Pharmacological Inhibition of AMP-Deaminase in Rat Cardiac Myocytes
T. Borkowski, C. Orlewska, E. M. Slominska, A. Yuen, M. Lipinski, I. Rybakowska, H. Foks, K. K. Kaletha, M. H. Yacoub & R. T. Smolenski
Pages: 867-871
Published online: 03 Jul 2008
AbstractforPharmacological Inhibition of AMP-Deaminase in Rat Cardiac Myocytes | Full Text | References | PDF (218.4 KB)
  • 105 Views
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Article
A Kinetic Study of the Rat Liver Adenosine Kinase Reverse Reaction
D. Vannoni, S. Giglioni, A. Santoro, E. Aceto, E. Marinello & R. Leoncini
Pages: 872-875
Published online: 03 Jul 2008
AbstractforA Kinetic Study of the Rat Liver Adenosine Kinase Reverse Reaction | Full Text | References | PDF (56.5 KB)
  • 49 Views
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Article
Modulation of AMP Deaminase in Rat Hearts Subjected to Ischemia and Reperfusion by Purine Riboside
T. Borkowski, M. Lipinski, R. Kaminski, E. Krzyminska-Stasiuk, M. Langowska, G. Raczak, E. M. Slominska & R. T. Smolenski
Pages: 876-880
Published online: 03 Jul 2008
AbstractforModulation of AMP Deaminase in Rat Hearts Subjected to Ischemia and Reperfusion by Purine Riboside | Full Text | References | PDF (64.2 KB)
  • 53 Views
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Pages: 881-887
Published online: 03 Jul 2008
AbstractforMechanism of Transition from Xanthine Dehydrogenase to Xanthine Oxidase: Effect of Guanidine-HCL or Urea on the Activity | Full Text | References | PDF (1.5 MB)
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Mechanism of Inhibition of Xanthine Oxidoreductase by Allopurinol: Crystal Structure of Reduced Bovine Milk Xanthine Oxidoreductase Bound with Oxipurinol
Ken Okamoto, Bryan T. Eger, Tomoko Nishino, Emil F. Pai & Takeshi Nishino
Pages: 888-893
Published online: 03 Jul 2008
AbstractforMechanism of Inhibition of Xanthine Oxidoreductase by Allopurinol: Crystal Structure of Reduced Bovine Milk Xanthine Oxidoreductase Bound with Oxipurinol | Full Text | References | PDF (1.4 MB)
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The Role for Glutamic Acid at Position 196 in Human Hypoxanthine Phosphoribosyltransferase (HPRT) as Investigated Using Site-Directed Mutagenesis
B. Canyuk, A. E-Wan, W. Keawwijit, T. Nualnoi, L. Sirisatean, P. Tansakul & C. Tanthana
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Published online: 03 Jul 2008
AbstractforThe Role for Glutamic Acid at Position 196 in Human Hypoxanthine Phosphoribosyltransferase (HPRT) as Investigated Using Site-Directed Mutagenesis | Full Text | References | PDF (263.5 KB)
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