1,716
Views
288
CrossRef citations to date
0
Altmetric
Drug Evaluations

N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

, , , &
Pages 1955-1962 | Published online: 06 Nov 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (31)

Azza S. Abdelhaffez, Ebtihal A. Abd El-Aziz, Maha B. Tohamy & Asmaa M. Ahmed. (2023) N-acetyl cysteine can blunt metabolic and cardiovascular effects via down-regulation of cardiotrophin-1 in rat model of fructose-induced metabolic syndrome. Archives of Physiology and Biochemistry 129:4, pages 854-869.
Read now
Hamed Hamedinasab, Ali Hossein Rezayan, Mahmoud Reza Jaafari, Mohammad Mashreghi & Hale Alvandi. (2023) The protective effect of N-acetylcysteine against liposome and chitosan-induced cytotoxicity. Journal of Microencapsulation 40:5, pages 357-365.
Read now
Farzaneh Motafeghi, Parham Mortazavi, Amir Hossein Salman Mahiny, Mohammad Mehdi Abtahi & Mohammad Shokrzadeh. (2023) The role of ginger’s extract and N-acetylcysteine against docetaxel-induced oxidative stress and genetic disorder. Drug and Chemical Toxicology 46:4, pages 617-624.
Read now
Riham Abdel-Hamid Haroun, Nahed Abdel-Aziz & Soha Saad. (2023) The protective effect of N-acetyl cysteine against selenium toxicity and gamma irradiation in rats. Drug and Chemical Toxicology 46:3, pages 482-490.
Read now
Mark F McCarty, Aaron Lerner, James J DiNicolantonio & Carina Benzvi. (2021) Nutraceutical Aid for Allergies – Strategies for Down-Regulating Mast Cell Degranulation. Journal of Asthma and Allergy 14, pages 1257-1266.
Read now
Mark F McCarty, James J DiNicolantonio & Aaron Lerner. (2021) Review – Nutraceuticals Can Target Asthmatic Bronchoconstriction: NADPH Oxidase-Dependent Oxidative Stress, RhoA and Calcium Dynamics. Journal of Asthma and Allergy 14, pages 685-701.
Read now
Aishwarya Dighal, Sritama De Sarkar, Lars Gille & Mitali Chatterjee. (2021) Can the iron content of culture media impact on the leishmanicidal effect of artemisinin?. Free Radical Research 55:3, pages 282-295.
Read now
Mehak Passi, Sadia Shahid, Sankarakuttalam Chockalingam, Isaac Kirubakaran Sundar & Gopinath Packirisamy. (2020) Conventional and Nanotechnology Based Approaches to Combat Chronic Obstructive Pulmonary Disease: Implications for Chronic Airway Diseases. International Journal of Nanomedicine 15, pages 3803-3826.
Read now
Vikash Chandra Tripathi, Soyar Horam, Anoop Singh, Manjul Lata, Thota Jagadeshwar Reddy, Jesu Arockiaraj & Mukesh Pasupuleti. (2020) The discovery of antioxidants in marine microorganisms and their protective effects on the hepatic cells from chemical-induced oxidative stress. Free Radical Research 54:2-3, pages 150-161.
Read now
Olivia M. Dean, Kylie Gray, Seetal Dodd, Kristi-Ann Villagonzalo, Ellie Brown, Bruce Tonge, Michael Berk & Linda K. Byrne. (2019) Does N-acetylcysteine improve behaviour in children with autism?: A mixed-methods analysis of the effects of N-acetylcysteine. Journal of Intellectual & Developmental Disability 44:4, pages 474-480.
Read now
Ra Jeong Kim, Young-Sool Hah, Ji-Yong Gwark & Hyung Bin Park. (2019) N-acetylcysteine reduces glutamate-induced cytotoxicity to fibroblasts of rat supraspinatus tendons. Connective Tissue Research 60:5, pages 431-443.
Read now
Giancarlo Aldini, Alessandra Altomare, Giovanna Baron, Giulio Vistoli, Marina Carini, Luisa Borsani & Francesco Sergio. (2018) N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why. Free Radical Research 52:7, pages 751-762.
Read now
Fanuel T. Hagos, Monica J. Daood, Jacob A. Ocque, Thomas D. Nolin, Hulya Bayir, Samuel M. Poloyac, Patrick M. Kochanek, Robert S. B. Clark & Philip E. Empey. (2017) Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine. Xenobiotica 47:4, pages 346-353.
Read now
Alessandro Minarini, Silvia Ferrari, Martina Galletti, Nina Giambalvo, Daniela Perrone, Giulia Rioli & Gian Maria Galeazzi. (2017) N-acetylcysteine in the treatment of psychiatric disorders: current status and future prospects. Expert Opinion on Drug Metabolism & Toxicology 13:3, pages 279-292.
Read now
Pierre Halteh, Richard K. Scher & Shari R. Lipner. (2017) Onychophagia: A nail-biting conundrum for physicians. Journal of Dermatological Treatment 28:2, pages 166-172.
Read now
Caixia Guo, Man Yang, Li Jing, Ji Wang, Yang Yu, Yang Li, Junchao Duan, Xianqing Zhou, Yanbo Li & Zhiwei Sun. (2016) Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling. International Journal of Nanomedicine 11, pages 5257-5276.
Read now
Benneth Ben-Azu, Adegbuyi Oladele Aderibigbe, Abayomi Mayowa Ajayi & Ezekiel Oluwagbenga Iwalewa. (2016) Neuroprotective effects of the ethanol stem bark extracts of Terminalia ivorensis in ketamine-induced schizophrenia-like behaviors and oxidative damage in mice. Pharmaceutical Biology 54:12, pages 2871-2879.
Read now
Pingping Yang, Yun Li & Gaosi Xu. (2016) Antioxidant therapy improves non-thyroidal illness syndrome in uremic rats. Renal Failure 38:4, pages 514-520.
Read now
Eduardo Prado, Michael Maes, Luiz Gustavo Piccoli, Marcela Baracat, Décio Sabattini Barbosa, Olavo Franco, Seetal Dodd, Michael Berk & Sandra Odebrecht Vargas Nunes. (2015) N-acetylcysteine for therapy-resistant tobacco use disorder: a pilot study. Redox Report 20:5, pages 215-222.
Read now
Nursu Cakin Memik, Ozlem Yildiz Gundogdu & Umit Tural. (2015) Use of N-acetylcysteine in Obsessive-Compulsive and Related Disorders. Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology 25:2, pages 193-206.
Read now
Majid Shohrati, Iman Karimzadeh, Amin Saburi, Hossein Khalili & Mostafa Ghanei. (2014) The role of N-acetylcysteine in the management of acute and chronic pulmonary complications of sulfur mustard: a literature review. Inhalation Toxicology 26:9, pages 507-523.
Read now
Mark F. McCarty & James J. DiNicolantonio. (2014) The Molecular Biology and Pathophysiology of Vascular Calcification. Postgraduate Medicine 126:2, pages 54-64.
Read now
Giancarlo Aldini, Giulio Vistoli, Milan Stefek, N. Chondrogianni, Tilman Grune, Jolanta Sereikaite, Izabela Sadowska-Bartosz & Grzegorz Bartosz. (2013) Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products. Free Radical Research 47:sup1, pages 93-137.
Read now
Bianca Pfaffenseller, Gabriel R Fries, Bianca Wollenhaupt-Aguiar, Gabriela D Colpo, Laura Stertz, Bruna Panizzutti, Pedro VS Magalhães & Flávio Kapczinski. (2013) Neurotrophins, inflammation and oxidative stress as illness activity biomarkers in bipolar disorder. Expert Review of Neurotherapeutics 13:7, pages 827-842.
Read now
K. Sunitha, M. Hemshekhar, R. M. Thushara, M. Sebastin Santhosh, M. Yariswamy, K. Kemparaju & K. S. Girish. (2013) N-Acetylcysteine amide: a derivative to fulfill the promises of N-Acetylcysteine. Free Radical Research 47:5, pages 357-367.
Read now
Misagh Alipour, Milton G. Smith, Kresimir Pucaj & Zacharias E. Suntres. (2012) Acute toxicity study of liposomal antioxidant formulations containing N-acetylcysteine, α-tocopherol, and γ-tocopherol in rats. Journal of Liposome Research 22:2, pages 158-167.
Read now
Eduardo Tavares Lima Trajano, Cinthya Sternberg, Maurício Caetano, Marco Aurélio Santos Silva, Luís Cristóvão Porto, Juliana Carvalho Santos, Marcelo Lima Ribeiro, Clarissa Bichara Magalhães, Walter Araújo Zin, Cláudia Farias Benjamim & Samuel Santos Valença. (2011) Endotoxin-induced acute lung injury is dependent upon oxidative response. Inhalation Toxicology 23:14, pages 918-926.
Read now
Letícia P Roma, Camila A M Oliveira, Everardo M Carneiro, Gabriela G Albuquerque, Antonio C Boschero & Kleber L A Souza. (2011) N-acetylcysteine protects pancreatic islet against glucocorticoid toxicity. Redox Report 16:4, pages 173-180.
Read now
Murat Kizilgun, Yavuz Poyrazoglu, Yesim Oztas, Halil Yaman, Erdinc Cakir, Tuncer Cayci, Ozgur Emin Akgul, Yasemin Gulcan Kurt, Hakan Yaren, Zeki Ilker Kunak, Enis Macit, Esin Ozkan, Mine Yavuz Taslipinar, Turker Turker & Ayhan Ozcan. (2011) Beneficial Effects of N-Acetylcysteine and Ebselen on Renal Ischemia/Reperfusion Injury. Renal Failure 33:5, pages 512-517.
Read now
DanielG. Amen, JosephC. Wu, Derek Taylor & Kristen Willeumier. (2011) Reversing Brain Damage in Former NFL Players: Implications for Traumatic Brain Injury and Substance Abuse Rehabilitation. Journal of Psychoactive Drugs 43:1, pages 1-5.
Read now
Kristi-Ann Villagonzalo, Seetal Dodd, Olivia Dean, Kylie Gray, Bruce Tonge & Michael Berk. (2010) Oxidative pathways as a drug target for the treatment of autism. Expert Opinion on Therapeutic Targets 14:12, pages 1301-1310.
Read now

Articles from other publishers (257)

Yue Feng, Junjing Wu, Runyu Lei, Yu Zhang, Mu Qiao, Jiawei Zhou, Zhong Xu, Zipeng Li, Hua Sun, Xianwen Peng & Shuqi Mei. (2023) N-Acetyl-L-Cysteine Ameliorates BPAF-Induced Porcine Sertoli Cell Apoptosis and Cell Cycle Arrest via Inhibiting the ROS Level. Toxics 11:11, pages 923.
Crossref
Junjie Lin, Chun Cui & Yunzi Feng. (2023) Preparation and Kokumi Properties of N-Acetyl-Val/Leu/Ile/Met/Phe in the Presence of Acetic Acid and Amino Acid: A Commercially Available Transglutaminase and Protease A 2SD. Journal of Agricultural and Food Chemistry.
Crossref
S. V. Zybleva, Yu. I. Rozhko, A. V. Zharikova, B. O. Kabeshev & S. L. Zyblev. (2023) The role N-acetylcysteine (nac) in the therapy of diseases characterized by oxidative stress (literature review). Medical and Biological Problems of Life Activity:2, pages 6-16.
Crossref
Ellen D. Herbst, David L. Pennington, Brian Borsari, Jennifer Manuel, Matthew Yalch, Eric Alcid, Madeline Martinez Rivas, Joannalyn Delacruz, Nathan Rossi, Brianna Garcia, Natalie Wong & Steven L. Batki. (2023) N-acetylcysteine for smoking cessation among dual users of tobacco and cannabis: Protocol and rationale for a randomized controlled trial. Contemporary Clinical Trials 131, pages 107250.
Crossref
Haibin Wu, Min Wei, Shen Hu, Pu Cheng, Shuhan Shi, Fan Xia, Lenan Xu, Lina Yin, Guang Liang, Fangyuan Li & Daishun Ling. (2023) A Photomodulable Bacteriophage‐Spike Nanozyme Enables Dually Enhanced Biofilm Penetration and Bacterial Capture for Photothermal‐Boosted Catalytic Therapy of MRSA Infections. Advanced Science 10:24.
Crossref
Ashraf M. Morgan, Hanan A. Ogaly, Shaimaa Kamel, Maha M. Rashad, Eman I. Hassanen, Marwa A. Ibrahim, Mona K. Galal, Aya M. Yassin, Sharah A. Al Dulmani, Fatimah A.M. Al-Zahrani & Ahmed M. Hussien. (2023) Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats. Journal of Veterinary Research 0:0.
Crossref
Rui Zhou, Lei Wang, Wenping Liu, Jin Li, Jun He, Yaqi Yao, Hongwei Yuan & Yanxu Chang. (2023) In‐capillary screening and quantifying the antioxidants of Yangxinshi Tablet using field‐enhanced sample injection‐micellar electrokinetic chromatography. Journal of Separation Science 46:13.
Crossref
Mahlagha Nikbaf-Shandiz, Shaghayegh Adeli, Amir Hossein Faghfouri, Fateme Khademi, Parsa Jamilian, Meysam Zarezadeh & Mehrangiz Ebrahimi-Mamaghani. (2023) The efficacy of N-acetylcysteine in improving liver function: A systematic review and meta-analysis of controlled clinical trials. PharmaNutrition 24, pages 100343.
Crossref
Arman Fesharaki Zadeh, Amy F. T. Arnsten & Min Wang. (2023) Scientific Rationale for the Treatment of Cognitive Deficits from Long COVID. Neurology International 15:2, pages 725-742.
Crossref
Diego Fernández-Lázaro, Carlos Domínguez-Ortega, Natalia Busto, Mirian Santamaría-Peláez, Enrique Roche, Eduardo Gutiérez-Abejón & Juan Mielgo-Ayuso. (2023) Influence of N-Acetylcysteine Supplementation on Physical Performance and Laboratory Biomarkers in Adult Males: A Systematic Review of Controlled Trials. Nutrients 15:11, pages 2463.
Crossref
Hirohisa Uehara, Yoshiaki Itoigawa, Daichi Morikawa, Akihisa Koga, Hironori Tsurukami, Yuichiro Maruyama & Muneaki Ishijima. (2023) The Effect of Vitamin C and N -Acetylcysteine on Tendon-to-Bone Healing in a Rodent Model of Rotator Cuff Repair . The American Journal of Sports Medicine 51:6, pages 1596-1607.
Crossref
Lital Argaev-Frenkel & Tovit Rosenzweig. (2023) Redox Balance in Type 2 Diabetes: Therapeutic Potential and the Challenge of Antioxidant-Based Therapy. Antioxidants 12:5, pages 994.
Crossref
Paola Brivio, Maria Teresa Gallo, Piotr Gruca, Magdalena Lason, Ewa Litwa, Fabio Fumagalli, Mariusz Papp & Francesca Calabrese. (2023) Chronic N-Acetyl-Cysteine Treatment Enhances the Expression of the Immediate Early Gene Nr4a1 in Response to an Acute Challenge in Male Rats: Comparison with the Antidepressant Venlafaxine. International Journal of Molecular Sciences 24:8, pages 7321.
Crossref
Simon Bernard Iloki Assanga, Lidianys María Lewis Luján, Mark F. McCarty & James J. DiNicolantonio. (2023) Nutraceutical and dietary resources for breast cancer prevention – Highlighting strategies for suppressing breast aromatase expression. PharmaNutrition 23, pages 100327.
Crossref
Paula Michele da Silva Schmidt, Jéssica Puchalski Trettim, Aline Longoni, Mateus Grings, Mariana Bonati de Matos, Luciana de Avila Quevedo, Ana Paula Ardais, Fernanda Nedel, Gabriele Ghisleni, Guilhian Leipnitz, Ricardo Tavares Pinheiro & Adriano Martimbianco de Assis. (2023) Can glutathione be a biomarker for suicide risk in women 18 months postpartum?. Frontiers in Psychiatry 14.
Crossref
Ekram Mohammadi, Farnaz Nikbakht, Somayeh Vazifekhah, Javad Fahanik Babae & Mohamad Taghi Jogataei. (2023) Evaluation the cognition-improvement effects of N-acetyl cysteine in experimental temporal lobe epilepsy in rat. Behavioural Brain Research 440, pages 114263.
Crossref
Jian Chen, Tianyu Chen, Yeyang Wang, Juanjuan Meng, Guangjiao Tan, Qiurong Zhao, Shilong Feng, Lixin Xu & Qinqin Pei. (2022) Oxidative stress disrupts the cytoskeleton of spinal motor neurons. Brain and Behavior 13:2.
Crossref
Annarita Stringaro, Maurizio Nordio & Monica Vazquez-Levin. 2023. A Clinical Guide to Inositols. A Clinical Guide to Inositols 197 211 .
Ashwag H. Alwadani, Soheir A. Almasri, Amal A. Aloud, Nawal A. Albadr, Ghedeir M. Alshammari & Mohammed Abdo Yahya. (2022) The Synergistic Protective Effect of γ-Oryzanol (OZ) and N-Acetylcysteine (NAC) against Experimentally Induced NAFLD in Rats Entails Hypoglycemic, Antioxidant, and PPARα Stimulatory Effects. Nutrients 15:1, pages 106.
Crossref
Joaquin Abelli, Gabriel Méndez-Valdés, Francisca Gómez-Hevia, Maria Chiara Bragato, Silvia Chichiarelli, Luciano Saso & Ramón Rodrigo. (2022) Potential Antioxidant Multitherapy against Complications Occurring in Sepsis. Biomedicines 10:12, pages 3088.
Crossref
Bohao Liu, Cong Ding, Wenbin Tang, Chen Zhang, Yiying Gu, Zhiqiang Wang, Tingzi Yu & Zhuan Li. (2022) Hepatic ROS Mediated Macrophage Activation Is Responsible for Irinotecan Induced Liver Injury. Cells 11:23, pages 3791.
Crossref
Lucas Sousa Magalhães, Enaldo Vieira Melo, Nayra Prata Damascena, Adriana Cardoso Batista Albuquerque, Camilla Natália Oliveira Santos, Mônica Cardozo Rebouças, Mariana de Oliveira Bezerra, Ricardo Louzada da Silva, Fabricia Alvisi de Oliveira, Priscila Lima Santos, João Santana da Silva, Michael Wheeler Lipscomb, Ângela Maria da Silva, Amélia Ribeiro de Jesus & Roque Pacheco de Almeida. (2022) Use of N-acetylcysteine as treatment adjuvant regulates immune response in visceral leishmaniasis: Pilot clinical trial and in vitro experiments. Frontiers in Cellular and Infection Microbiology 12.
Crossref
Jin Vivian Lee, Connor Engel, Shirli Tay, Gayan DeSilva, Kshitij Desai, John Cashin, Clay F. Semenkovich & Mohamed A. Zayed. (2022) Impact of N-Acetyl-Cysteine on Ischemic Stumps Following Major Lower Extremity Amputation. Annals of Surgery 276:5, pages e302-e310.
Crossref
Syed A. A. Rizvi, George P. Einstein, Orien L. Tulp, Frantz Sainvil & Rolando Branly. (2022) Introduction to Traditional Medicine and Their Role in Prevention and Treatment of Emerging and Re-Emerging Diseases. Biomolecules 12:10, pages 1442.
Crossref
Amirhossein Yazdi, Nakisa Khansari, Maryam Mehrpooya, Younes Mohammadi & Shiva Zareie. (2021) Oral N-acetylcysteine as an adjunct to standard medical therapy improved heart function in cases with stable class II and III systolic heart failure. Irish Journal of Medical Science (1971 -) 191:5, pages 2063-2075.
Crossref
Martha E. Lyon & Andrew W. Lyon. (2021) N-Acetylcysteine Interference with a Glucose Dehydrogenase Linked Glucose Meter. Journal of Diabetes Science and Technology 16:5, pages 1114-1119.
Crossref
Paulina M. Getsy, Santhosh M. Baby, Walter J. May, Tristan H.J. Lewis, James N. Bates, Yee-Hsee Hsieh, Benjamin Gaston & Stephen J. Lewis. (2022) L-NAC reverses of the adverse effects of fentanyl infusion on ventilation and blood-gas chemistry. Biomedicine & Pharmacotherapy 153, pages 113277.
Crossref
Farshad Yadollahi, Shahriyar Salehitali, Ahmad Hormaty & Farokh Yadollahi. (2022) The effect of endotracheal administration of N-acetyl cysteine and heparin on the level of secretion and partial thromboplastin time in acute respiratory distress syndrome patients under mechanical ventilation: A randomized clinical trial study. Journal of Shahrekord University of Medical Sciences 24:3, pages 117-121.
Crossref
Xueping Yu, Xiupeng Wang, Lue Sun, Atsushi Yamazaki & Xia Li. (2022) Tumor microenvironment regulation - enhanced radio - immunotherapy. Biomaterials Advances 138, pages 212867.
Crossref
Abolfazl Barzegari, Yadollah Omidi, Rebecca Landon, Virginie Gueguen, Sepideh Parvizpour, Anne Meddahi-Pellé, Fani Anagnostou & Graciela Pavon-Djavid. (2022) The protective effect of N-acetylcysteine on antimycin A-induced respiratory chain deficiency in mesenchymal stem cells. Chemico-Biological Interactions 360, pages 109937.
Crossref
Laiba Rind, Mohammad Ahmad, Mohammad Irfan Khan, Badruddeen, Juber Akhtar, Usama Ahmad, Chandan Yadav & Mohammad Owais. (2022) An insight on safety, efficacy, and molecular docking study reports of N-acetylcysteine and its compound formulations. Journal of Basic and Clinical Physiology and Pharmacology 33:3, pages 223-233.
Crossref
Guangshan Zhao, Lian Yang, Wenshen Zhong, Yuze Hu, Yu Tan, Zhe Ren, Qiuyan Ban, Chung S. Yang, Yifei Wang & Zhiping Wang. (2022) Polydatin, A Glycoside of Resveratrol, Is Better Than Resveratrol in Alleviating Non-alcoholic Fatty Liver Disease in Mice Fed a High-Fructose Diet. Frontiers in Nutrition 9.
Crossref
Pasquale Ambrosino, Tiziana Bachetti, Silvestro Ennio D’Anna, Brurya Galloway, Andrea Bianco, Vito D’Agnano, Antimo Papa, Andrea Motta, Fabio Perrotta & Mauro Maniscalco. (2022) Mechanisms and Clinical Implications of Endothelial Dysfunction in Arterial Hypertension. Journal of Cardiovascular Development and Disease 9:5, pages 136.
Crossref
Ramón Rodrigo, Catalina Retamal, Denisse Schupper, Diego Vergara-Hernández, Sarmistha Saha, Elisabetta Profumo, Brigitta Buttari & Luciano Saso. (2022) Antioxidant Cardioprotection against Reperfusion Injury: Potential Therapeutic Roles of Resveratrol and Quercetin. Molecules 27:8, pages 2564.
Crossref
Jiawen Liao, Roya Gheissari, Duncan C. Thomas, Frank D. Gilliland, Fred Lurmann, Khandaker Talat Islam & Zhanghua Chen. (2022) Transcriptomic and metabolomic associations with exposures to air pollutants among young adults with childhood asthma history. Environmental Pollution 299, pages 118903.
Crossref
James J DiNicolantonio, Mark F McCarty, Simon Iloki Assanga, Lidianys Lewis Lujan & James H O'Keefe. (2022) Ferulic acid and berberine, via Sirt1 and AMPK, may act as cell cleansing promoters of healthy longevity. Open Heart 9:1, pages e001801.
Crossref
Mahdi Satvati, Najmeh Salehi-Vanani, Ali Nouri & Esfandiar Heidarian. (2022) Protective effects of N-acetyl cysteine against oxidative stress in ibuprofen-induced hepatotoxicity in rats. Comparative Clinical Pathology 31:2, pages 293-301.
Crossref
Xiaojing WangQirong LuJingchao GuoIrma AresMarta MartínezMaría-Rosa Martínez-LarrañagaXu Wang, Arturo AnadónMaría-Aránzazu Martínez. (2022) Oxidative Stress and Metabolism: A Mechanistic Insight for Glyphosate Toxicology. Annual Review of Pharmacology and Toxicology 62:1, pages 617-639.
Crossref
Shinae HwangJong-Keun Kim. (2022) N-Acetylcysteine Induces Apoptotic, Oxidative and Excitotoxic Neuronal Death in Mouse Cortical Cultures. Chonnam Medical Journal 58:1, pages 18.
Crossref
Lucie E. Bourne, Jessal J. Patel, Bethan K. Davies, Ellen Neven, Anja Verhulst, Patrick C. D'Haese, Caroline P. D. Wheeler‐Jones & Isabel R. Orriss. (2021) N ‐acetylcysteine (NAC) differentially affects arterial medial calcification and bone formation: The role of l ‐cysteine and hydrogen sulphide . Journal of Cellular Physiology 237:1, pages 1070-1086.
Crossref
Mark F. McCarty & James J. DiNicolantonio. (2021) Maintaining Effective Beta Cell Function in the Face of Metabolic Syndrome-Associated Glucolipotoxicity—Nutraceutical Options. Healthcare 10:1, pages 3.
Crossref
Guodong Li, Hao Liu, Ruibing Feng, Tian-Shu Kang, Wanhe Wang, Chung-Nga Ko, Chun-Yuen Wong, Min Ye, Dik-Lung Ma, Jian-Bo Wan & Chung-Hang Leung. (2021) A bioactive ligand-conjugated iridium(III) metal-based complex as a Keap1–Nrf2 protein-protein interaction inhibitor against acetaminophen-induced acute liver injury. Redox Biology 48, pages 102129.
Crossref
Lauren Arancini, Mohammadreza Mohebbi, Michael Berk, Olivia M. Dean, Chiara C. Bortolasci, Briana Spolding, Robson Zazula & Seetal Dodd. (2021) A placebo-controlled, randomised pilot trial of N-acetylcysteine or placebo for cessation of tobacco smoking. European Neuropsychopharmacology 53, pages 120-126.
Crossref
José Fábio Santos Duarte Lana, Anna Vitória Santos Duarte Lana, Quézia Souza Rodrigues, Gabriel Silva Santos, Riya Navani, Annu Navani, Lucas Furtado da Fonseca, Gabriel Ohana Marques Azzini, Thiago Setti, Tomas Mosaner, Claudio Lopes Simplicio & Taís Mazzini Setti. (2021) Nebulization of glutathione and N-Acetylcysteine as an adjuvant therapy for COVID-19 onset. Advances in Redox Research 3, pages 100015.
Crossref
Esther P. Bonitto, Brendan T. McKeown & Kerry B. Goralski. (2021) Jadomycins: A potential chemotherapy for multi‐drug resistant metastatic breast cancer. Pharmacology Research & Perspectives 9:6.
Crossref
Nourhan Mohammed, Sahar A Ahmed, Nagah I Hegazy & Kamal Kashishy. (2021) Ameliorative effects of hesperidin and N -acetylcysteine against formaldehyde-induced-hemato- and genotoxicity . Toxicology Research 10:5, pages 992-1002.
Crossref
Piotr Pietruski, Wiktor Paskal, Łukasz Paluch, Adriana M. Paskal, Żaneta Nitek, Paweł Włodarski, Jerzy Walecki & Bartłomiej Noszczyk. (2020) The Impact of N-Acetylcysteine on Autologous Fat Graft: First-in-Human Pilot Study. Aesthetic Plastic Surgery 45:5, pages 2397-2405.
Crossref
Ramón Rodrigo, Juan Carlos Prieto, Rubén Aguayo, Cristóbal Ramos, Ángel Puentes, Abraham Gajardo, Emiliano Panieri, Catalina Rojas-Solé, José Lillo-Moya & Luciano Saso. (2021) Joint Cardioprotective Effect of Vitamin C and Other Antioxidants against Reperfusion Injury in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention. Molecules 26:18, pages 5702.
Crossref
Maria Nunzia De Luca, Marisa Colone, Riccardo Gambioli, Annarita Stringaro & Vittorio Unfer. (2021) Oxidative Stress and Male Fertility: Role of Antioxidants and Inositols. Antioxidants 10:8, pages 1283.
Crossref
Jonathan Paulo Agnes, Vitória Wibbelt dos Santos, Raquel Nascimento das Neves, Rosângela Mayer Gonçalves, Marina Delgobo, Carolina Saibro Girardi, Débora Denardin Lückemeyer, Marcella de Amorim Ferreira, Sérgio José Macedo-Júnior, Samantha Cristiane Lopes, Fernando Spiller, Daniel Pens Gelain, José Cláudio Fonseca Moreira, Rui Daniel Prediger, Juliano Ferreira & Alfeu Zanotto-Filho. (2021) Antioxidants Improve Oxaliplatin-Induced Peripheral Neuropathy in Tumor-Bearing Mice Model: Role of Spinal Cord Oxidative Stress and Inflammation. The Journal of Pain 22:8, pages 996-1013.
Crossref
Xiaohong Li, Shengwen He, Jian Zhou, Xiaoli Yu, Lanhua Li, Yumei Liu & Wanwei Li. (2021) Cr (VI) induces abnormalities in glucose and lipid metabolism through ROS/Nrf2 signaling. Ecotoxicology and Environmental Safety 219, pages 112320.
Crossref
Asmaa R. Hashim, Dina W. Bashir, Noha A. E. Yasin, Mona K. Galal & El-Gharbawy S. M.. (2021) Ameliorative effect of N-acetylcysteine against glyphosate-induced hepatotoxicity in adult male albino rats: histopathological, biochemical, and molecular studies. Environmental Science and Pollution Research 28:31, pages 42275-42289.
Crossref
Micaely Cristina dos Santos Tenório, Nayara Gomes Graciliano, Fabiana Andréa Moura, Alane Cabral Menezes de Oliveira & Marília Oliveira Fonseca Goulart. (2021) N-Acetylcysteine (NAC): Impacts on Human Health. Antioxidants 10:6, pages 967.
Crossref
Solomon E. Owumi, Ayomide P. Akomolafe, Innocent O. Imosemi, Oyeronke A. Odunola & Adegboyega K. Oyelere. (2021) N ‐acetyl cysteine co‐treatment abates perfluorooctanoic acid‐induced reproductive toxicity in male rats . Andrologia 53:5.
Crossref
Iman M. Ahmad, Alicia J. Dafferner, Kelly A. O’Connell, Kamiya Mehla, Bradley E. Britigan, Michael A. Hollingsworth & Maher Y. Abdalla. (2021) Heme Oxygenase-1 Inhibition Potentiates the Effects of Nab-Paclitaxel-Gemcitabine and Modulates the Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma. Cancers 13:9, pages 2264.
Crossref
Nafiseh Mardani, Samaneh Mozafarpoor, Azadeh Goodarzi & Farahnaz Nikkhah. (2021) A systematic review of N‐acetylcysteine for treatment of acne vulgaris and acne‐related associations and consequences: Focus on clinical studies. Dermatologic Therapy 34:3.
Crossref
James J DiNicolantonio, Mark F McCarty, Jorge Barroso-Aranda, Simon Assanga, Lidianys Maria Lewis Lujan & James H O'Keefe. (2021) A nutraceutical strategy for downregulating TGFβ signalling: prospects for prevention of fibrotic disorders, including post-COVID-19 pulmonary fibrosis. Open Heart 8:1, pages e001663.
Crossref
Yehudit Shabat, Yoav Lichtenstein & Yaron Ilan. (2020) Short-Term Cohousing of Sick with Healthy or Treated Mice Alleviates the Inflammatory Response and Liver Damage. Inflammation 44:2, pages 518-525.
Crossref
Alessandra Fraternale, Carolina Zara, Marta De Angelis, Lucia Nencioni, Anna Teresa Palamara, Michele Retini, Tomas Di Mambro, Mauro Magnani & Rita Crinelli. (2021) Intracellular Redox-Modulated Pathways as Targets for Effective Approaches in the Treatment of Viral Infection. International Journal of Molecular Sciences 22:7, pages 3603.
Crossref
Mark F. McCarty. (2021) Nutraceutical, Dietary, and Lifestyle Options for Prevention and Treatment of Ventricular Hypertrophy and Heart Failure. International Journal of Molecular Sciences 22:7, pages 3321.
Crossref
Xiao-Jun Huang. (2021) Overcoming graft failure after haploidentical transplantation: Is this a possibility?. Best Practice & Research Clinical Haematology 34:1, pages 101255.
Crossref
Mark F. McCarty, James J. DiNicolantonio & Aaron Lerner. (2021) A Fundamental Role for Oxidants and Intracellular Calcium Signals in Alzheimer’s Pathogenesis—And How a Comprehensive Antioxidant Strategy May Aid Prevention of This Disorder. International Journal of Molecular Sciences 22:4, pages 2140.
Crossref
Jingjing Li, Renkai Li, Xiaoping Wu, Ruby Lai-Chong Hoo, Simon Ming-Yuen Lee, Timothy Man-Yau Cheung, Bryan Siu-Yin Ho & George Pak-Heng Leung. (2021) Amauroderma rugosum Protects PC12 Cells against 6-OHDA-Induced Neurotoxicity through Antioxidant and Antiapoptotic Effects. Oxidative Medicine and Cellular Longevity 2021, pages 1-15.
Crossref
Aliasghar Ghafarizadeh, Mahdi Malmir, Samira Naderi Noreini & Tayebeh Faraji. (2020) Antioxidant effects of N‐acetylcysteine on the male reproductive system: A systematic review. Andrologia 53:1.
Crossref
Tonali Blanco Ayala, Daniela Ramírez Ortega, Paulina Ovalle Rodríguez, Benjamín Pineda, Gonzalo Pérez de la Cruz, Dinora González Esquivel, Robert Schwarcz, Korrapati V. Sathyasaikumar, Anabel Jiménez Anguiano & Verónica Pérez de la Cruz. (2021) Subchronic N-acetylcysteine Treatment Decreases Brain Kynurenic Acid Levels and Improves Cognitive Performance in Mice. Antioxidants 10:2, pages 147.
Crossref
Linda S. May-ZhangAnnet KiraboJiansheng HuangMacRae F. LintonSean S. DaviesKatherine T. Murray. (2021) Scavenging Reactive Lipids to Prevent Oxidative Injury. Annual Review of Pharmacology and Toxicology 61:1, pages 291-308.
Crossref
Marta Celorrio, James Rhodes, Sangeetha Vadivelu, McKenzie Davies & Stuart H. Friess. (2021) N-acetylcysteine reduces brain injury after delayed hypoxemia following traumatic brain injury. Experimental Neurology 335, pages 113507.
Crossref
Elif Ersoy Çallıoğlu, Sami Berçin, Gülçin Başdemir, Muzaffer Kiriş, İlkan Tatar, Arzu Tuzuner, Tolga Oğuzhan, Tuba Müderris, Mustafa Fevzi Sargon & Mehmet Hakan Korkmaz. (2020) The effect of N-acetyl cysteine on biofilm layers in an experimental model of chronic otitis mediaL’effetto della N-acetil cisteina sullo strato di biofilm in un modello sperimentale di otite media cronica. Acta Otorhinolaryngologica Italica 40:6, pages 457-462.
Crossref
Mahtab Zarei, Meysam Zarezadeh, Fateme Khademi, Shaghayegh Adeli, Fateme Abbaszade, Omid Nikpayam, Parisa Janmohammadi, Niyaz Mohammadzadeh Honarvar, Nazanin Hazhir Karzar, Zohreh Ghoreishi & Alireza Ostadrahimi. (2020) What are the effects of N-acetylcysteine supplementation on anthropometric indices? A systematic review and meta-analysis of clinical trials. PharmaNutrition 14, pages 100238.
Crossref
Pokpong Piriyakhuntorn, Adisak Tantiworawit, Mattabhorn Phimphilai, Krekwit Shinlapawittayatorn, Siriporn C. Chattipakorn & Nipon Chattipakorn. (2020) Impact of iron overload on bone remodeling in thalassemia. Archives of Osteoporosis 15:1.
Crossref
Jiaxin Zong, Jieyi Cheng, Yuanfeng Fu, Jing Song, Weisong Pan, Li Yang, Ting Zhang & Mingmei Zhou. (2020) Serum Metabolomic Profiling Reveals the Amelioration Effect of Methotrexate on Imiquimod-Induced Psoriasis in Mouse. Frontiers in Pharmacology 11.
Crossref
Mohammadreza Askari, Roghaye Faryabi, Hadis Mozaffari & Manije Darooghegi Mofrad. (2020) The effects of N-Acetylcysteine on serum level of inflammatory biomarkers in adults. Findings from a systematic review and meta-analysis of randomized clinical trials. Cytokine 135, pages 155239.
Crossref
Gillian D. Mahumane, Pradeep Kumar, Viness Pillay & Yahya E. Choonara. (2020) Repositioning N-Acetylcysteine (NAC): NAC-Loaded Electrospun Drug Delivery Scaffolding for Potential Neural Tissue Engineering Application. Pharmaceutics 12:10, pages 934.
Crossref
Jamal Hallajzadeh, Alireza MilajerdiŽeljko ReinerFariba KolahdoozZatollah Asemi. (2020) The Effects of N-acetylcysteine on Inflammatory Markers and Homocysteine: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Pharmaceutical Sciences 26:3, pages 214-224.
Crossref
T. Blanco-Ayala, K.V. Sathyasaikumar, J.D. Uys, V. Pérez-de-la-Cruz, L.S. Pidugu & R. Schwarcz. (2020) N-Acetylcysteine Inhibits Kynurenine Aminotransferase II. Neuroscience 444, pages 160-169.
Crossref
Jie Zhou, Marcia R. Terluk, Lisa Basso, Usha R. Mishra, Paul J. Orchard, James C. Cloyd, Henning Schröder & Reena V. Kartha. (2020) N-acetylcysteine Provides Cytoprotection in Murine Oligodendrocytes through Heme Oxygenase-1 Activity. Biomedicines 8:8, pages 240.
Crossref
Mary-Frances E. Hall & Frank C. Church. (2020) Integrative Medicine and Health Therapy for Parkinson Disease. Topics in Geriatric Rehabilitation 36:3, pages 176-186.
Crossref
Kavoos Tahmasebi, Mahvash Jafari, Farideh Izadi, Alireza Asgari, Hoosein Bahadoran, Javad Heydari & Saeed Khazaie. (2020) Evaluation of Prophylactic and Therapeutic Roles of N-Acetylcysteine on Biochemical and Oxidative Changes Induced by Acute Poisoning of Diazinon in Various Rat Tissues. Current Chemical Biology 14:2, pages 100-116.
Crossref
Madeleine Polet, Laurie Laloux, Sébastien Cambier, Johanna Ziebel, Arno C. Gutleb & Yves-Jacques Schneider. (2020) Soluble silver ions from silver nanoparticles induce a polarised secretion of interleukin-8 in differentiated Caco-2 cells. Toxicology Letters 325, pages 14-24.
Crossref
Andrea Carlo Rossetti, Maria Serena Paladini, Marco Andrea Riva & Raffaella Molteni. (2020) Oxidation-reduction mechanisms in psychiatric disorders: A novel target for pharmacological intervention. Pharmacology & Therapeutics 210, pages 107520.
Crossref
Yik-Lam Cho, Hayden Weng Siong Tan, Quaiser Saquib, Yi Ren, Javed Ahmad, Rizwan Wahab, Weifeng He, Boon-Huat Bay & Han-Ming Shen. (2020) Dual role of oxidative stress-JNK activation in autophagy and apoptosis induced by nickel oxide nanoparticles in human cancer cells. Free Radical Biology and Medicine 153, pages 173-186.
Crossref
Guangshan Zhao, Ruixia Dong, Jianyuan Teng, Lian Yang, Tao Liu, Ximing Wu, Yufeng He, Zhiping Wang, Hanlin Pu & Yifei Wang. (2020) N -Acetyl- l -cysteine Enhances the Effect of Selenium Nanoparticles on Cancer Cytotoxicity by Increasing the Production of Selenium-Induced Reactive Oxygen Species . ACS Omega 5:20, pages 11710-11720.
Crossref
Mark F. McCarty & Aaron Lerner. (2020) Nutraceuticals Targeting Generation and Oxidant Activity of Peroxynitrite May Aid Prevention and Control of Parkinson’s Disease. International Journal of Molecular Sciences 21:10, pages 3624.
Crossref
Velid Unsal, Tahir Dalkiran, Mustafa Çiçek & Engin Kölükçü. (2020) The Role of Natural Antioxidants Against Reactive Oxygen Species Produced by Cadmium Toxicity: A Review. Advanced Pharmaceutical Bulletin 10:2, pages 184-202.
Crossref
Serena Notartomaso, Pamela Scarselli, Giada Mascio, Francesca Liberatore, Emanuela Mazzon, Santa Mammana, Agnese Gugliandolo, Giorgio Cruccu, Valeria Bruno, Ferdinando Nicoletti & Giuseppe Battaglia. (2020) N-Acetylcysteine causes analgesia in a mouse model of painful diabetic neuropathy. Molecular Pain 16, pages 174480692090429.
Crossref
In-Young Chung, Bi-o Kim, Hye-Jeong Jang & You-Hee Cho. (2020) Repositioning of a mucolytic drug to a selective antibacterial against Vibrio cholerae. Journal of Microbiology 58:1, pages 61-66.
Crossref
Deanna K. Bauerlein, Hashem N. Akbar, Erik C. von Rosenvinge, Nora D. Loughry & Preeti R. John. (2019) Benefit of N -Acetylcysteine in Postoperative Hepatic Dysfunction: Case Report and Review of Literature . Case Reports in Hepatology 2019, pages 1-4.
Crossref
Lauren Arancini, Chiara C. Bortolasci, Seetal Dodd, Olivia M. Dean & Michael Berk. (2019) N-acetylcysteine for cessation of tobacco smoking: rationale and study protocol for a randomised controlled trial. Trials 20:1.
Crossref
Jionghan Zhuang, Gaohui Nie, Fan Yang, Xueyan Dai, Huabin Cao, Chenghong Xing, Guoliang Hu & Caiying Zhang. (2019) Cadmium induces cytotoxicity through oxidative stress-mediated apoptosis pathway in duck renal tubular epithelial cells. Toxicology in Vitro 61, pages 104625.
Crossref
Josiane Silva Silveira, Géssica Luana Antunes, Daniela Benvenutti Kaiber, Mariana Severo da Costa, Eduardo Peil Marques, Fernanda Silva Ferreira, Rodrigo Benedetti Gassen, Ricardo Vaz Breda, Angela T. S. Wyse, Paulo Pitrez & Aline Andrea da Cunha. (2019) Reactive oxygen species are involved in eosinophil extracellular traps release and in airway inflammation in asthma. Journal of Cellular Physiology 234:12, pages 23633-23646.
Crossref
Joseph Firth, Scott B. Teasdale, Kelly Allott, Dan Siskind, Wolfgang Marx, Jack Cotter, Nicola Veronese, Felipe Schuch, Lee Smith, Marco Solmi, André F. Carvalho, Davy Vancampfort, Michael Berk, Brendon Stubbs & Jerome Sarris. (2019) The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta‐review of meta‐analyses of randomized controlled trials. World Psychiatry 18:3, pages 308-324.
Crossref
G. Paul Amminger & Maximus Berger. 2019. Clinical Staging in Psychiatry. Clinical Staging in Psychiatry 221 240 .
Manal El Hamamsy, Rasha Bondok, Sara Shaheen & Ghada Hussein Eladly. (2019) Safety and efficacy of adding intravenous N-acetylcysteine to parenteral L-alanyl-L-glutamine in hospitalized patients undergoing surgery of the colon: a randomized controlled trial. Annals of Saudi Medicine 39:4, pages 251-257.
Crossref
James J DiNicolantonio & Mark McCarty. (2019) Autophagy-induced degradation of Notch1, achieved through intermittent fasting, may promote beta cell neogenesis: implications for reversal of type 2 diabetes. Open Heart 6:1, pages e001028.
Crossref
Yuan Kong, Yu Wang, Yuan-Yuan Zhang, Min-Min Shi, Xiao-Dong Mo, Yu-Qian Sun, Ying-Jun Chang, Lan-Ping Xu, Xiao-Hui Zhang, Kai-Yan Liu & Xiao-Jun Huang. (2019) Prophylactic oral NAC reduced poor hematopoietic reconstitution by improving endothelial cells after haploidentical transplantation. Blood Advances 3:8, pages 1303-1317.
Crossref
Tara L. Braun, Viraat Patel, Logan C. DeBord & Theodore Rosen. (2019) A review of N‐acetylcysteine in the treatment of grooming disorders. International Journal of Dermatology 58:4, pages 502-510.
Crossref
Kristine K Dennis, Young-Mi Go & Dean P Jones. (2019) Redox Systems Biology of Nutrition and Oxidative Stress. The Journal of Nutrition 149:4, pages 553-565.
Crossref
Lital Argaev Frenkel, Hava Rozenfeld, Konstantin Rozenberg, Sanford R Sampson & Tovit Rosenzweig. (2019) N-Acetyl-l-Cysteine Supplement in Early Life or Adulthood Reduces Progression of Diabetes in Nonobese Diabetic Mice. Current Developments in Nutrition 3:4, pages 3004004.
Crossref
Ruhi Turkmen, Yavuz Osman Birdane, Hasan Huseyin Demirel, Hidayet Yavuz, Mustafa Kabu & Sinan Ince. (2019) Antioxidant and cytoprotective effects of N-acetylcysteine against subchronic oral glyphosate-based herbicide-induced oxidative stress in rats. Environmental Science and Pollution Research 26:11, pages 11427-11437.
Crossref
Huizhen Wang & Xin Zhang. (2019) ROS Reduction Does Not Decrease the Anticancer Efficacy of X-Ray in Two Breast Cancer Cell Lines. Oxidative Medicine and Cellular Longevity 2019, pages 1-12.
Crossref
Uzoma S Ikonne, Philip H Vann, Jessica M Wong, Michael J Forster & Nathalie Sumien. (2019) Supplementation with N-Acetyl Cysteine Affects Motor and Cognitive Function in Young but Not Old Mice. The Journal of Nutrition 149:3, pages 463-470.
Crossref
Xingguo Zhu, Aluya R Oseghale, Lopez H Nicole, Biaoru Li & Betty S Pace. (2019) Mechanisms of NRF2 activation to mediate fetal hemoglobin induction and protection against oxidative stress in sickle cell disease. Experimental Biology and Medicine 244:2, pages 171-182.
Crossref
Pernille Kempel Ellegaard, Rasmus Wentzer Licht, René Ernst Nielsen, Olivia May Dean, Michael Berk, Henrik Enghusen Poulsen, Mohammadreza Mohebbi & Connie Thuroee Nielsen. (2019) The efficacy of adjunctive N-acetylcysteine in acute bipolar depression: A randomized placebo-controlled study. Journal of Affective Disorders 245, pages 1043-1051.
Crossref
Anselm Chi‐wai Lee & LeLe Aung. (2018) Treatment of hepatic veno‐occlusive disease in children with N ‐acetylcysteine . Pediatric Blood & Cancer 66:2.
Crossref
Geetika Garg, Abhishek Kumar Singh, Sandeep Singh & Syed Ibrahim Rizvi. 2019. Nutraceuticals and Natural Product Derivatives. Nutraceuticals and Natural Product Derivatives 25 37 .
Lawrence Fung & Antonio Hardan. 2019. The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine. The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine 53 72 .
Nicholas L. DePace & Joseph ColomboNicholas L. DePace & Joseph Colombo. 2019. Clinical Autonomic and Mitochondrial Disorders. Clinical Autonomic and Mitochondrial Disorders 139 254 .
Lara M. Gomes, Giselli Scaini, Milena Carvalho-Silva, Maria L. Gomes, Fernanda Malgarin, Luiza W. Kist, Maurício R. Bogo, Eduardo Pacheco Rico, Alexandra I. Zugno, Pedro F. P. Deroza, Gislaine Z. Réus, Airam B. de Moura, João Quevedo, Gustavo C. Ferreira, Patrícia F. Schuck & Emilio L. Streck. (2018) Antioxidants Reverse the Changes in the Cholinergic System Caused by L-Tyrosine Administration in Rats. Neurotoxicity Research 34:4, pages 769-780.
Crossref
Xinjian Yu, Ri-Qing Yu, Duan Gui, Xiyang Zhang, Fenping Zhan, Xian Sun & Yuping Wu. (2018) Hexavalent chromium induces oxidative stress and mitochondria-mediated apoptosis in isolated skin fibroblasts of Indo-Pacific humpback dolphin. Aquatic Toxicology 203, pages 179-186.
Crossref
Liwen Bao, Jun Bo, Bo Jin, Nanqing Xiong, Huanchun Ni, Jian Li, Xinping Luo, Haiming Shi & Jinjin Zhang. (2018) Clinical Features of CINin ChineseVery Elderly Patients Undergoing Coronary Angiography Procedure With Hydration Treatment: A Three-Center, Prospective Study. International Journal of Gerontology 12:3, pages 196-199.
Crossref
Jia-Ru Wang, Gui-Nan Shen, Ying-Hua Luo, Xian-Ji Piao, Meng Shen, Chang Liu, Yue Wang, Ling-Qi Meng, Yi Zhang, Hao Wang, Jin-Qian Li, Wan-Ting Xu, Yang Liu, Hu-Nan Sun, Ying-Hao Han, Mei-Hua Jin, Long-Kui Cao & Cheng-Hao Jin. (2018) The compound 2-(naphthalene-2-thio)-5,8-dimethoxy-1,4-naphthoquinone induces apoptosis via reactive oxygen species-regulated mitogen-activated protein kinase, protein kinase B, and signal transducer and activator of transcription 3 signaling in human gast. Drug Development Research 79:6, pages 295-306.
Crossref
AT Jannuzzi, M Kara & B Alpertunga. (2017) Celastrol ameliorates acetaminophen-induced oxidative stress and cytotoxicity in HepG2 cells. Human & Experimental Toxicology 37:7, pages 742-751.
Crossref
Yuan Kong, Min-Min Shi, Yuan-Yuan Zhang, Xie-Na Cao, Yu Wang, Xiao-Hui Zhang, Lan-Ping Xu & Xiao-Jun Huang. (2018) N-acetyl-L-cysteine improves bone marrow endothelial progenitor cells in prolonged isolated thrombocytopenia patients post allogeneic hematopoietic stem cell transplantation. American Journal of Hematology 93:7, pages 931-942.
Crossref
Prachi Gupta, Brendan L. Thompson, Banrida Wahlang, Carolyn T. Jordan, J. Zach Hilt, Bernhard Hennig & Thomas Dziubla. (2017) The environmental pollutant, polychlorinated biphenyls, and cardiovascular disease: a potential target for antioxidant nanotherapeutics. Drug Delivery and Translational Research 8:3, pages 740-759.
Crossref
Dahae Lee, Chang-Eop Kim, Sa-Yoon Park, Kem Kim, Nguyen Hiep, Dongho Lee, Hyuk-Jai Jang, Jae Lee & Ki Kang. (2018) Protective Effect of Artemisia argyi and Its Flavonoid Constituents against Contrast-Induced Cytotoxicity by Iodixanol in LLC-PK1 Cells. International Journal of Molecular Sciences 19:5, pages 1387.
Crossref
Lin Zhang, Shuqin Xu, Qingjun Huang & Haiyun Xu. (2018) N-acetylcysteine attenuates the cuprizone-induced behavioral changes and oligodendrocyte loss in male C57BL/7 mice via its anti-inflammation actions. Journal of Neuroscience Research 96:5, pages 803-816.
Crossref
Meir Mizrahi, Tomer Adar, Gadi Lalazar, Dean Nachman, Madi El Haj, Ami Ben Ya’acov, Yoav Lichtenstein, Yehudit Shabat, Dimitri Kanovich, Lida Zolotarov & Yaron Ilan. (2018) Glycosphingolipids Prevent APAP and HMG-CoA Reductase Inhibitors-mediated Liver Damage: A Novel Method for “Safer Drug” Formulation that Prevents Drug-induced Liver Injury. Journal of Clinical and Translational Hepatology 6:2, pages 1-8.
Crossref
Zahra Sepehrmanesh, Mahsa Heidary, Negar Akasheh, Hossein Akbari & Mahshid Heidary. (2018) Therapeutic effect of adjunctive N-acetyl cysteine (NAC) on symptoms of chronic schizophrenia: A double-blind, randomized clinical trial. Progress in Neuro-Psychopharmacology and Biological Psychiatry 82, pages 289-296.
Crossref
Jason Chertoff. (2017) N -Acetylcysteine’s Role in Sepsis and Potential Benefit in Patients With Microcirculatory Derangements . Journal of Intensive Care Medicine 33:2, pages 87-96.
Crossref
Junaid Bhatti, Barto Nascimento, Umbreen Akhtar, Shawn G. Rhind, Homer Tien, Avery Nathens & Luis Teodoro da Luz. (2018) Systematic Review of Human and Animal Studies Examining the Efficacy and Safety of N-Acetylcysteine (NAC) and N-Acetylcysteine Amide (NACA) in Traumatic Brain Injury: Impact on Neurofunctional Outcome and Biomarkers of Oxidative Stress and Inflammation. Frontiers in Neurology 8.
Crossref
Mohammad Adil, SyedSuhail Amin & Mohd Mohtashim. (2018) N-acetylcysteine in dermatology. Indian Journal of Dermatology, Venereology and Leprology 84:6, pages 652.
Crossref
Tian-Shin Yeh. 2018. Braddom's Rehabilitation Care: A Clinical Handbook. Braddom's Rehabilitation Care: A Clinical Handbook 126 128.e7 .
Yuexia Zhang, Zhenhua Yang, Yunzhu Chen, Ruijin Li, Hong Geng, Wenjuan Dong, Zongwei Cai & Chuan Dong. (2017) Fine chalk dust induces inflammatory response via p38 and ERK MAPK pathway in rat lung. Environmental Science and Pollution Research 25:2, pages 1742-1751.
Crossref
Nicholas P. Murphy & Kyle J. Lampe. (2017) Fabricating PLGA microparticles with high loads of the small molecule antioxidant N‐acetylcysteine that rescue oligodendrocyte progenitor cells from oxidative stress. Biotechnology and Bioengineering 115:1, pages 246-256.
Crossref
Stewart I. Head. (2017) Antioxidant therapy in a mouse model of Duchenne muscular dystrophy: some promising results but with a weighty caveat. The Journal of Physiology 595:23, pages 7015-7015.
Crossref
Lei Wang, Jia Zhou, Yongqing Hou, Dan Yi, Binying Ding, Jiaqian Xie, Yue Zhang, Hongbo Chen, Tao Wu, Di Zhao, Chien-An Andy Hu & Guoyao Wu. (2017) N-Acetylcysteine supplementation alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus. Amino Acids 49:12, pages 1931-1943.
Crossref
Steven R. Hall, Jay Toulany, Leah G. Bennett, Camilo F. Martinez-Farina, Andrew W. Robertson, David L. Jakeman & Kerry B. Goralski. (2017) Jadomycins Inhibit Type II Topoisomerases and Promote DNA Damage and Apoptosis in Multidrug-Resistant Triple-Negative Breast Cancer Cells. Journal of Pharmacology and Experimental Therapeutics 363:2, pages 196-210.
Crossref
Usmah Kawoos, Richard M. McCarron & Mikulas Chavko. (2017) Protective Effect of N-Acetylcysteine Amide on Blast-Induced Increase in Intracranial Pressure in Rats. Frontiers in Neurology 8.
Crossref
Daniel Monti, Federica Sotgia, Diana Whitaker-Menezes, Madalina Tuluc, Ruth Birbe, Adam Berger, Melissa Lazar, Paolo Cotzia, Rossitza Draganova-Tacheva, Zhao Lin, Marina Domingo-Vidal, Andrew Newberg, Michael P. Lisanti & Ubaldo Martinez-Outschoorn. (2017) Pilot study demonstrating metabolic and anti-proliferative effects of in vivo anti-oxidant supplementation with N-Acetylcysteine in Breast Cancer. Seminars in Oncology 44:3, pages 226-232.
Crossref
Yuyong Liu, Ke Liu, Nian Wang & Huali Zhang. (2017) N-acetylcysteine induces apoptosis via the mitochondria-dependent pathway but not via endoplasmic reticulum stress in H9c2 cells. Molecular Medicine Reports 16:5, pages 6626-6633.
Crossref
James J DiNicolantonio, James H OKeefe & Mark F McCarty. (2017) Boosting endogenous production of vasoprotective hydrogen sulfide via supplementation with taurine and N-acetylcysteine: a novel way to promote cardiovascular health. Open Heart 4:1, pages e000600.
Crossref
Dimitrios Alexandropoulos, Gerasimos V. Bazigos, Ilias P. Doulamis, Aspasia Tzani, Panagiotis Konstantopoulos, Nikolitsa Tragotsalou, Agathi Kondi-Pafiti, Thomas Kotsis, Nikolaos Arkadopoulos, Vasileios Smyrniotis & Despina N. Perrea. (2017) Protective effects of N-acetylcystein and atorvastatin against renal and hepatic injury in a rat model of intestinal ischemia-reperfusion. Biomedicine & Pharmacotherapy 89, pages 673-680.
Crossref
Qinting Zhang, Wu Hong, Haozhe Li, Fanglan Peng, Fan Wang, Ningning Li, Hui Xiang, Zongfeng Zhang, Yousong Su, Yueqi Huang, Shengyu Zhang, Guoqin Zhao, Rubai Zhou, Ling Mao, Zhiguang Lin, Weixiong Cai, Yiru Fang, Bin Xie & Min Zhao. (2017) Increased ratio of high sensitivity C-reactive protein to interleukin-10 as a potential peripheral biomarker of schizophrenia and aggression. International Journal of Psychophysiology 114, pages 9-15.
Crossref
Ra Jeong Kim, Jae-Ran Kang, Young-Sool Hah & Hyung Bin Park. (2017) N-acetyl cysteine protects cells from chondrocyte death induced by local anesthetics. Journal of Orthopaedic Research 35:2, pages 297-303.
Crossref
E.U. Nwose, P.T. Bwititi & V.M. Oguoma. 2017. Medicinal Spices and Vegetables from Africa. Medicinal Spices and Vegetables from Africa 109 131 .
E. Chávez, M. Galicia-Moreno & P. Muriel. 2017. Liver Pathophysiology. Liver Pathophysiology 729 742 .
Dean J. Wright, Thibault Renoir, Laura J. Gray & Anthony J. Hannan. 2017. Neurodegenerative Diseases. Neurodegenerative Diseases 93 128 .
Sicong Tu & Jian Tu. 2017. Neurological Regeneration. Neurological Regeneration 13 48 .
Rehab Mahmoud Abdel-Baky, Mohamed Abdullah Ali, Gamal El-Din Ali A. Abuo-Rahma & Neveen AbdelAziz. 2017. Advances in Microbiology, Infectious Diseases and Public Health. Advances in Microbiology, Infectious Diseases and Public Health 99 113 .
P Liceras-Boillos, R García-Navas, A Ginel-Picardo, B Anta, M Pérez-Andrés, C Lillo, C Gómez, D Jimeno, A Fernández-Medarde, F C Baltanás & E Santos. (2016) Sos1 disruption impairs cellular proliferation and viability through an increase in mitochondrial oxidative stress in primary MEFs. Oncogene 35:50, pages 6389-6402.
Crossref
Sa’ed H. Zyoud, W. Stephen Waring, Samah W. Al-Jabi, Waleed M. Sweileh & Rahmat Awang. (2016) The 100 most influential publications in paracetamol poisoning treatment: a bibliometric analysis of human studies. SpringerPlus 5:1.
Crossref
Paola Cardiano, Claudia Foti & Ottavia Giuffrè. (2016) On the interaction of N -acetylcysteine with Pb 2+ , Zn 2+ , Cd 2+ and Hg 2+. Journal of Molecular Liquids 223, pages 360-367.
Crossref
Hassan Karimi-Maleh, Mehdi Hatami, Reza Moradi, Mohammad A. Khalilzadeh, Sedighe Amiri & Hasan Sadeghifar. (2016) Synergic effect of Pt-Co nanoparticles and a dopamine derivative in a nanostructured electrochemical sensor for simultaneous determination of N-acetylcysteine, paracetamol and folic acid. Microchimica Acta 183:11, pages 2957-2964.
Crossref
Gerardo Cabanillas & Andrea Popescu-Martinez. (2016) N-Acetylcysteine for Relapsing Thrombotic Thrombocytopenic Purpura: More Evidence of a Promising Drug. American Journal of Therapeutics 23:5, pages e1277-e1279.
Crossref
Marilena Raciti, Jennie Ong, Laura Weis, Karin Edoff, Cristina Battagli, Anna Falk & Sandra Ceccatelli. (2016) Glucocorticoids alter neuronal differentiation of human neuroepithelial-like cells by inducing long-lasting changes in the reactive oxygen species balance. Neuropharmacology 107, pages 422-431.
Crossref
Yang Shen, Nai-jun Miao, Jin-lan Xu, Xin-xin Gan, Dan Xu, Li Zhou, Hong Xue, Wei Zhang & Li-min Lu. (2016) N-acetylcysteine alleviates angiotensin II-mediated renal fibrosis in mouse obstructed kidneys. Acta Pharmacologica Sinica 37:5, pages 637-644.
Crossref
Daofeng You, Yanli Ren, Shuying Huo, Jingran Dong, Shuguang Ren & Tiesheng Shi. (2016) A kinetic analysis of oxidation of the antioxidant N-acetyl-l-cysteine (NAC) by Pt(IV) complexes. Transition Metal Chemistry 41:3, pages 295-304.
Crossref
Nabeel Hamzeh, Li Li, Briana Barkes, Jie Huang, Beth Canono, May Gillespie, Lisa Maier & Brian Day. (2016) The effect of an oral anti-oxidant, N-Acetyl-cysteine, on inflammatory and oxidative markers in pulmonary sarcoidosis. Respiratory Medicine 112, pages 106-111.
Crossref
Chun-Lin Ye & Yi-Feng Lai. (2014) 2′,4′-Dihydroxy-6′-methoxy-3′,5′-dimethylchalcone, from buds of Cleistocalyx operculatus, induces apoptosis in human hepatoma SMMC-7721 cells through a reactive oxygen species-dependent mechanism. Cytotechnology 68:2, pages 331-341.
Crossref
Mallikarjun Handigund, Tae Won Bae, Jaehyeon Lee & Yong Gon Cho. (2016) Evaluation of in vitro storage characteristics of cold stored platelet concentrates with N acetylcysteine (NAC). Transfusion and Apheresis Science 54:1, pages 127-138.
Crossref
Frank Balszuweit, Georg Menacher, Annette Schmidt, Kai Kehe, Tanja Popp, Franz Worek, Horst Thiermann & Dirk Steinritz. (2016) Protective effects of the thiol compounds GSH and NAC against sulfur mustard toxicity in a human keratinocyte cell line. Toxicology Letters 244, pages 35-43.
Crossref
Fadime Atalay, Fehmi Odabasoglu, Mesut Halici, Elif Cadirci, Ozlem Aydin, Zekai Halici & Ahmet Cakir. (2016) N -Acetyl Cysteine Has Both Gastro-Protective and Anti-Inflammatory Effects in Experimental Rat Models: Its Gastro-Protective Effect Is Related to Its In Vivo and In Vitro Antioxidant Properties . Journal of Cellular Biochemistry 117:2, pages 308-319.
Crossref
Pedro Lobos, Barbara Bruna, Alex Cordova, Pablo Barattini, Jose Luis Galáz, Tatiana Adasme, Cecilia Hidalgo, Pablo Muñoz & Andrea Paula-Lima. (2016) Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of A β -Oligomers . Neural Plasticity 2016, pages 1-13.
Crossref
Afshin Amini, Samar Masoumi-Moghaddam & David L. MorrisAfshin Amini, Samar Masoumi-Moghaddam & David L. Morris. 2016. Utility of Bromelain and N-Acetylcysteine in Treatment of Peritoneal Dissemination of Gastrointestinal Mucin-Producing Malignancies. Utility of Bromelain and N-Acetylcysteine in Treatment of Peritoneal Dissemination of Gastrointestinal Mucin-Producing Malignancies 81 98 .
P. Mikolka, J. Kopincova, L. Tomcikova Mikusiakova, P. Kosutova, A. Calkovska & D. Mokra. 2016. Pulmonary Dysfunction and Disease. Pulmonary Dysfunction and Disease 63 75 .
Kívia de Andrade, Fabiana Moura, John dos Santos, Orlando de Araújo, Juliana de Farias Santos & Marília Goulart. (2015) Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine. International Journal of Molecular Sciences 16:12, pages 30269-30308.
Crossref
Mohamed Montassar Lasram, Ines Bini Dhouib, Alya Annabi, Saloua El Fazaa & Najoua Gharbi. (2015) A review on the possible molecular mechanism of action of N-acetylcysteine against insulin resistance and type-2 diabetes development. Clinical Biochemistry 48:16-17, pages 1200-1208.
Crossref
Ali Jahanban-Esfahlan, Vahid Panahi-Azar & Sanaz Sajedi. (2015) Spectroscopic and molecular docking studies on the interaction between N -acetyl cysteine and bovine serum albumin . Biopolymers 103:11, pages 638-645.
Crossref
João D. Seixas, Miguel Chaves‐Ferreira, Diana Montes‐Grajales, Ana M. Gonçalves, Ana R. Marques, Lígia M. Saraiva, Jesus Olivero‐Verbel, Carlos C. Romão & Gonçalo J. L. Bernardes. (2015) An N ‐Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species . Chemistry – A European Journal 21:42, pages 14708-14712.
Crossref
Mark F. McCarty & James J. DiNicolantonio. (2015) An increased need for dietary cysteine in support of glutathione synthesis may underlie the increased risk for mortality associated with low protein intake in the elderly. AGE 37:5.
Crossref
B. Jin, B.W. Wu, J.J. Zhang, X.P. Luo & H.M. Shi. (2015) Preventive effect of reduced glutathione on contrast-induced nephropathy in elderly patients undergoing coronary angiography or intervention: a randomized, controlled trial. Brazilian Journal of Medical and Biological Research 48:9, pages 839-842.
Crossref
Mohamed Abd-Elbaset, El-Shaimaa A. Arafa, Gamal A. El Sherbiny, Mohamed S. Abdel-Bakky & Abdel Nasser A.M. Elgendy. (2015) Quercetin modulates iNOS, eNOS and NOSTRIN expressions and attenuates oxidative stress in warm hepatic ischemia-reperfusion injury in rats. Beni-Suef University Journal of Basic and Applied Sciences 4:3, pages 246-255.
Crossref
Chia-Yi Tseng, Jing-Fen Chang, Jhih-Syuan Wang, Yu-Jung Chang, Marion K. Gordon & Ming-Wei Chao. (2015) Protective Effects of N-Acetyl Cysteine against Diesel Exhaust Particles-Induced Intracellular ROS Generates Pro-Inflammatory Cytokines to Mediate the Vascular Permeability of Capillary-Like Endothelial Tubes. PLOS ONE 10:7, pages e0131911.
Crossref
Nasim Kashef, Shima Karami & Gholamreza Esmaeeli Djavid. (2015) Phototoxic effect of hypericin alone and in combination with acetylcysteine on Staphylococcus aureus biofilms. Photodiagnosis and Photodynamic Therapy 12:2, pages 186-192.
Crossref
Frank T Zindo, Jacques Joubert & Sarel F Malan. (2015) Propargylamine as functional moiety in the design of multifunctional drugs for neurodegenerative disorders: MAO inhibition and beyond. Future Medicinal Chemistry 7:5, pages 609-629.
Crossref
Hyo Kyun Chung, Yong Kyung Kim, Ji-Hoon Park, Min Jeong Ryu, Joon Young Chang, Jung Hwan Hwang, Chul-Ho Lee, Soon-Ha Kim, Hyun Jin Kim, Gi Ryang Kweon, Koon Soon Kim & Minho Shong. (2015) The indole derivative NecroX-7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation . Liver International 35:4, pages 1341-1353.
Crossref
Ahmed Abdal Dayem, Hye Yeon Choi, Young Bong Kim & Ssang-Goo Cho. (2015) Antiviral Effect of Methylated Flavonol Isorhamnetin against Influenza. PLOS ONE 10:3, pages e0121610.
Crossref
Marianne Skov, Tacjana Pressler, Jens Lykkesfeldt, Henrik Enghusen Poulsen, Peter Østrup Jensen, Helle Krogh Johansen, Tavs Qvist, Dorthe Kræmer, Niels Høiby & Oana Ciofu. (2015) The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection — A pilot study. Journal of Cystic Fibrosis 14:2, pages 211-218.
Crossref
Steven R. Hall, Heather L. Blundon, Matthew A. Ladda, Andrew W. Robertson, Camilo F. Martinez‐Farina, David L. Jakeman & Kerry B. Goralski. (2015) Jadomycin breast cancer cytotoxicity is mediated by a copper‐dependent, reactive oxygen species–inducing mechanism. Pharmacology Research & Perspectives 3:2.
Crossref

Displaying 200 of 288 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.