Leukemia & Lymphoma, Volume 63, Issue 13 (2022)

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Leukemia & Lymphoma, Volume 63, Issue 13 (2022)

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Commentary

Article Commentary
The enigma of LAG3 receptor in hematological malignancies
Natalia Kreiniz, Aaron Polliack & Tamar Tadmor
Pages: 3019-3020
Published online: 25 Oct 2022
CitationforThe enigma of LAG3 receptor in hematological malignancies | Full Text | References | PDF (240.3 KB) | EPUB
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Reviews

Review
Development of a distributed international patient data registry for hairy cell leukemia
Leslie A. Andritsos, Mirela Anghelina, Jasmine Neal, James S. Blachly, Puneet Mathur, Omkar Lele, Claire Dearden, Sunil Iyengar, Matthew Cross, Clive S. Zent, Kerry A. Rogers, Narendranath Epperla, Gerard Lozanski, Christopher C. Oakes, Eric Kraut, Amy S. Ruppert, Qiuhong Zhao, Seema A. Bhat, Francesco Forconi, Versha Banerji, Sasanka Handunnetti, Constantine S. Tam, John F. Seymour, Monica Else, Robert J. Kreitman, Alan Saven, Timothy Call, Sameer A. Parikh, Farhad Ravandi, James B. Johnston, Enrico Tiacci, Xavier Troussard, Martin S. Tallman, Sascha Dietrich, Tamar Tadmor, Alessandro Gozzetti, Pier Luigi Zinzani, Tadeusz Robak, Graeme Quest, Judit Demeter, Kanti Rai, Soledad A. Fernandez & Michael Grever
Pages: 3021-3031
Published online: 07 Sep 2022
AbstractforDevelopment of a distributed international patient data registry for hairy cell leukemia | Full Text | References | PDF (3.2 MB) | EPUB
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Open Access
Review
T cell redirecting bispecific antibodies for multiple myeloma: emerging therapeutic strategies in a changing treatment landscape
Dickran Kazandjian, Andrew Kowalski & Ola Landgren
Pages: 3032-3043
Published online: 05 Sep 2022
AbstractforT cell redirecting bispecific antibodies for multiple myeloma: emerging therapeutic strategies in a changing treatment landscape | Full Text | References | PDF (1.3 MB) | EPUB
  • 686 Views
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Review
Brain-derived neurotrophic factor: focus on the pathogenesis of multiple myeloma and the development of treatment-induced peripheral neuropathy
Karolina Łuczkowska, Piotr Kulig, Bartłomiej Baumert & Bogusław Machaliński
Pages: 3044-3051
Published online: 23 Aug 2022
AbstractforBrain-derived neurotrophic factor: focus on the pathogenesis of multiple myeloma and the development of treatment-induced peripheral neuropathy | Full Text | References | PDF (1.2 MB) | EPUB
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Articles

Article
Matching-adjusted indirect comparison of axi-cel and liso-cel in relapsed or refractory large B-cell lymphoma
Olalekan O. Oluwole, Jenny M.H Chen, Keith Chan, Anik R. Patel, Jeroen P. Jansen, Sam Keeping, Yan Zheng, Julia T. Snider & Frederick L. Locke
Pages: 3052-3062
Published online: 01 Sep 2022
AbstractforMatching-adjusted indirect comparison of axi-cel and liso-cel in relapsed or refractory large B-cell lymphoma | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 857 Views
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Article
Final results of brentuximab vedotin combined with ifosfamide-carboplatin-etoposide in first refractory/relapsed Hodgkin lymphoma: a lymphoma study association phase I/II study
Aspasia Stamatoullas, Hervé Ghesquières, Pierre Feugier, Marc André, Fabien Le Bras, Anne-Claire Gac, Cécile Borel, Thomas Gastinne, Philippe Quittet, Franck Morschhauser, Vincent Ribrag, Stephanie Guidez, Emmanuelle Nicolas-Virelizier, Alina Berriolo-Riedinger, Thierry Vander Borght, Véronique Edeline & Pauline Brice
Pages: 3063-3071
Published online: 17 Aug 2022
AbstractforFinal results of brentuximab vedotin combined with ifosfamide-carboplatin-etoposide in first refractory/relapsed Hodgkin lymphoma: a lymphoma study association phase I/II study | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 506 Views
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Article
Extra copy number of BCL2 is correlated with increased BCL-2 protein expression and poor survival in diffuse large B-cell lymphoma treated with chemoimmunotherapy
Hee Sang Hwang, Hyun-Jung Sung, Mee-Jeong Kim, Dok Hyun Yoon, Chan-Sik Park, Jooryung Huh & Heounjeong Go
Pages: 3072-3081
Published online: 27 Sep 2022
AbstractforExtra copy number of BCL2 is correlated with increased BCL-2 protein expression and poor survival in diffuse large B-cell lymphoma treated with chemoimmunotherapy | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Article
Analysis of albumin as a prognostic factor in HHV-8/HIV-negative Castleman disease from a multicenter study
Tiantian Yu, Qing-Qing Cai, Qiong-Li Zhai, Ling Li, Xiaosheng Fang, Jianyong Li, Ruifang Sun, Hanjin Yang, Zhaoming Wang, Wenbian Qian, Zijun Y. Xu-Monette, Ken H. Young & Li Yu
Pages: 3082-3091
Published online: 07 Sep 2022
AbstractforAnalysis of albumin as a prognostic factor in HHV-8/HIV-negative Castleman disease from a multicenter study | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
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Open Access
Article
Allogeneic hematopoietic stem cell transplantation with myeloablative conditioning regimen for blastic plasmacytoid dendritic cell neoplasm patients in complete remission: a single center study
Yue Lu, Rui-Juan Sun, Jian-Ping Zhang, Fang Xu, Zhi-Cong Du, Ge-Le Tong, Yun Wang & Dao-Pei Lu
Pages: 3092-3099
Published online: 06 Sep 2022
AbstractforAllogeneic hematopoietic stem cell transplantation with myeloablative conditioning regimen for blastic plasmacytoid dendritic cell neoplasm patients in complete remission: a single center study | Full Text | References | PDF (762.2 KB) | EPUB
  • 150 Views
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Article
Successful and safe response to ibrutinib alone in treating relapsed Waldenström macrogobulinemia and related acquired von Willebrand syndrome: an option to consider
Alexandre Butelet, Stéphanie Poulain, Emmanuelle Jeanpierre, Micha Srour, Morgane Nudel, Paul Chauvet, Anne Bauters, Sophie Susen, Annabelle Dupont & Marie de Charette
Pages: 3100-3104
Published online: 13 Sep 2022
AbstractforSuccessful and safe response to ibrutinib alone in treating relapsed Waldenström macrogobulinemia and related acquired von Willebrand syndrome: an option to consider | Full Text | References | PDF (1.5 MB) | EPUB
  • 152 Views
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Article
Clinical and molecular profiling of AML patients with chromosome 7 or 7q deletions in the context of TP53 alterations and venetoclax treatment
Hussein A. Abbas, Edward Ayoub, Hanxiao Sun, Rashmi Kanagal-Shamanna, Nicholas J. Short, Ghayas Issa, Musa Yilmaz, Sherry Pierce, Daniel Rivera, Brent Cham, Shane Wing, Ziyi Li, Danielle Hammond, Elias Jabbour, Gautam Borthakur, Guillermo Garcia-Manero, Michael Andreeff, Naval Daver, Tapan Kadia, Marina Konopleva, Courtney DiNardo & Farhad Ravandi
Pages: 3105-3116
Published online: 10 Sep 2022
AbstractforClinical and molecular profiling of AML patients with chromosome 7 or 7q deletions in the context of TP53 alterations and venetoclax treatment | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Article
Weight-adjusted urinary creatinine excretion predicts transplant outcomes in adult patients with acute myeloid leukemia in complete remission
Akihito Nagata, Yuki Otsuka, Ryosuke Konuma, Hiroto Adachi, Atsushi Wada, Yuya Kishida, Tatsuya Konishi, Yuta Yamada, Ryohei Nagata, Yuma Noguchi, Atsushi Marumo, Junichi Mukae, Takashi Toya, Aiko Igarashi, Yuho Najima, Takeshi Kobayashi, Hisashi Sakamaki, Kazuteru Ohashi & Noriko Doki
Pages: 3117-3127
Published online: 06 Sep 2022
AbstractforWeight-adjusted urinary creatinine excretion predicts transplant outcomes in adult patients with acute myeloid leukemia in complete remission | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 104 Views
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Article
Adolescents and young adults (AYA) with acute myeloid leukemia (AML): real-world long-term results and age-specific outcomes
Chrysavgi Lalayanni, Christos Demosthenous, Michail Iskas, Charikleia Kelaidi, Maria Papathanasiou, Antonia Syrigou, Anastasia Athanasiadou, Apostolia Papalexandri, Ioannis Batsis, Anna Vardi, Sophia Polychronopoulou & Ioanna Sakellari
Pages: 3128-3137
Published online: 24 Aug 2022
AbstractforAdolescents and young adults (AYA) with acute myeloid leukemia (AML): real-world long-term results and age-specific outcomes | Full Text | References | PDF (1.6 MB) | EPUB
  • 271 Views
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Article
Patient-reported outcomes of patients with myelofibrosis or essential thrombocythemia enrolled in the MOST study
Ellen Ritchie, Anas Al-Janadi, Craig Kessler, Robyn Scherber, Tricia Kalafut, Haobo Ren & Ruben Mesa
Pages: 3138-3153
Published online: 07 Oct 2022
AbstractforPatient-reported outcomes of patients with myelofibrosis or essential thrombocythemia enrolled in the MOST study | Full Text | References | PDF (2 MB) | EPUB
  • 1994 Views
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Open Access
Article
MDM2 antagonist improves therapeutic activity of azacitidine in myelodysplastic syndromes and chronic myelomonocytic leukemia
Yue Wei, Hong Zheng, Pamela Pennington Lockyer, Faezeh Darbaniyan, Ziyi Li, Rashmi Kanagal-Shamanna, Kelly A. Soltysiak, Hui Yang, Irene Ganan-Gomez, Guillermo Montalban-Bravo, Kelly S. Chien, Kim-Anh Do, Naval Daver & Guillermo Garcia-Manero
Pages: 3154-3164
Published online: 05 Sep 2022
AbstractforMDM2 antagonist improves therapeutic activity of azacitidine in myelodysplastic syndromes and chronic myelomonocytic leukemia | Full Text | References | PDF (2.9 MB) | EPUB
  • 292 Views
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Article
A natural history of lower-risk myelodysplastic syndromes with ring sideroblasts: an analysis of the MDS-CAN registry
Rena Buckstein, Lisa Chodirker, Lee Mozessohn, Karen W.L Yee, Michelle Geddes, Nancy Zhu, April Shamy, Heather A. Leitch, Grace Christou, Versha Banerji, Leber Brian, Dina Khalaf, Eve St-Hilaire, Nicholas Finn, Thomas Nevill, Mary-Margaret Keating, John Storring, Robert Delage, Anne Parmentier, Aksharh Thambipillai, Mohammed Siddiqui, Christopher Westcott, Chris Cameron, Alexandre Mamedov, Paul Spin & Derek Tang
Pages: 3165-3174
Published online: 12 Sep 2022
AbstractforA natural history of lower-risk myelodysplastic syndromes with ring sideroblasts: an analysis of the MDS-CAN registry | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 2234 Views
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Open Access
Article
Calcific tendinopathy: an unexpected side effect of tyrosine kinase inhibitor?
Alice Canon, Lydia Roy, Xavier Chevalier, Stéphane Giraudier & Florent Eymard
Pages: 3175-3180
Published online: 02 Sep 2022
AbstractforCalcific tendinopathy: an unexpected side effect of tyrosine kinase inhibitor? | Full Text | References | PDF (775.9 KB) | EPUB
  • 107 Views
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Article
Dynamics of minimal residual disease defines a novel risk-classification and the role of allo-HSCT in adult Ph-negative B-cell acute lymphoblastic leukemia
Zihong Cai, Yiqian Liu, Bingqing Tang, Zhengwei Wu, Zhixiang Wang, Ren Lin, Xiuli Xu, Zicong Huang, Jiawang Ou, Xiaofang Li, Xiaoli Liu, Qifa Liu & Hongsheng Zhou
Pages: 3181-3190
Published online: 13 Sep 2022
AbstractforDynamics of minimal residual disease defines a novel risk-classification and the role of allo-HSCT in adult Ph-negative B-cell acute lymphoblastic leukemia | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 176 Views
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Article
Treatment-related toxicities associated with hospitalization in children, adolescents, and young adults with acute lymphoblastic leukemia: population level analysis
Natasha S. Namjoshi, Theresa H. M. Keegan, Qian C. Li, Jong H. Chung, Jennifer L. Rosenthal, Lena E. Winestone, Lori Muffly, Marcio H. Malogolowkin & Elysia M. Alvarez
Pages: 3191-3199
Published online: 23 Aug 2022
AbstractforTreatment-related toxicities associated with hospitalization in children, adolescents, and young adults with acute lymphoblastic leukemia: population level analysis | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 175 Views
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Article
Clinicopathologic and genetic evaluation of B-lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 (iAMP21) in adult patients
Taylor Zak, Juehua Gao, Amir Behdad, Jayesh Mehta, Jessica K. Altman, Peng Ji, Xinyan Lu & Madina Sukhanova
Pages: 3200-3207
Published online: 22 Aug 2022
AbstractforClinicopathologic and genetic evaluation of B-lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 (iAMP21) in adult patients | Full Text | References | PDF (1.6 MB) | EPUB
  • 152 Views
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Article
Prognostic factors and outcomes of infant acute lymphoblastic leukemia (ALL), hypodiploid ALL, and mixed-phenotype acute leukemia (MPAL) in Canada: a report from CYP-C
Pauline Tibout, Omar Ledjiar, Uma Athale, Meera Rayar, Ketan Kulkarni, Tony Truong, Sonia Cellot, Henrique Bittencourt, Marie-Claude Pelland-Marcotte & Thai Hoa Tran
Pages: 3208-3216
Published online: 06 Sep 2022
AbstractforPrognostic factors and outcomes of infant acute lymphoblastic leukemia (ALL), hypodiploid ALL, and mixed-phenotype acute leukemia (MPAL) in Canada: a report from CYP-C | Full Text | References | PDF (918.1 KB) | EPUB
  • 1305 Views
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Open Access

Letters to the Editor

Ruxolitinib bridging therapy to allogeneic SCT for high-risk refractory subcutaneous panniculitis-like T-cell lymphoma
Leisa R. Watson, Thomas E. Lew, Lucy C. Fox, Amit Khot & Carrie van der Weyden
Pages: 3217-3221
Published online: 07 Sep 2022
First Page PreviewforRuxolitinib bridging therapy to allogeneic SCT for high-risk refractory subcutaneous panniculitis-like T-cell lymphoma | Full Text | References | PDF (1.3 MB) | EPUB
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Distinct immune-response profile of Richter transformation chronic lymphocytic leukemia (CLL), defined by high expression of PD1, LAG3, TIM3 and IL-10
Amir Behdad, Matthew John Schipma, Shuo Ma, Yi-Hua Chen & Qing Ching Chen
Pages: 3222-3226
Published online: 14 Sep 2022
First Page PreviewforDistinct immune-response profile of Richter transformation chronic lymphocytic leukemia (CLL), defined by high expression of PD1, LAG3, TIM3 and IL-10 | Full Text | References | PDF (927.1 KB) | EPUB
  • 154 Views
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Transcriptional deregulation of LSD1 and LSD2 is associated with cytogenetic risk in chronic lymphocytic leukemia
Daniel Freitas da Costa, Luma Dayane de Carvalho Filiú-Braga, Amandda Évelin Silva-Carvalho, Josiane Lilian Schiavinato, Maria Catarina Cals de Vasconcelos, Lorena Lôbo de Figueiredo-Pontes, Antonio Roberto Lucena-Araujo & Felipe Saldanha-Araujo
Pages: 3227-3231
Published online: 25 Aug 2022
First Page PreviewforTranscriptional deregulation of LSD1 and LSD2 is associated with cytogenetic risk in chronic lymphocytic leukemia | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 156 Views
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Clinical experience with venetoclax and hypomethylating agents (HMA) in patients with newly diagnosed and relapsed or refractory KMT2A-Rearranged acute myeloid leukemia (AML)
Brian J. Ball, Shukaib Arslan, Paul Koller, Dat Ngo, Michelle Afkhami, Amandeep Salhotra, Monzr Al-Malki, Ahmed Aribi, Haris Ali, Karamjeet Sandhu, Salman Otoukesh, Idoroenyi Amanam, Hoda Pourhassan, Andrew Artz, Peter Curtin, Anthony Stein, Ryotaro Nakamura, Guido Marcucci, Eileen Smith, Vinod Pullarkat & Ibrahim Aldoss
Pages: 3232-3236
Published online: 10 Sep 2022
First Page PreviewforClinical experience with venetoclax and hypomethylating agents (HMA) in patients with newly diagnosed and relapsed or refractory KMT2A-Rearranged acute myeloid leukemia (AML) | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 373 Views
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Single and multiple point NRAS mutations in acute myeloid leukemia: a study of 327 well molecularly characterized patients
Anna Durinikova, Adam Folta, Filip Pardy, Jan Svaton, Marie Drncova, Barbora Weinbergerova, Petr Cetkovsky, Zdenek Racil, Pavel Jindra, Tomas Szotkowski, Pavel Zak, Jiri Mayer & Ivana Jeziskova
Pages: 3237-3240
Published online: 01 Sep 2022
First Page PreviewforSingle and multiple point NRAS mutations in acute myeloid leukemia: a study of 327 well molecularly characterized patients | Full Text | References | PDF (1.2 MB) | EPUB
  • 177 Views
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Successful brentuximab vedotin and nivolumab therapy of multiply refractory diffuse large B-cell lymphoma with Hodgkin features
Victor Zibara, Filiz Sen, Michael Scordo & Lorenzo Falchi
Pages: 3241-3244
Published online: 18 Sep 2022
First Page PreviewforSuccessful brentuximab vedotin and nivolumab therapy of multiply refractory diffuse large B-cell lymphoma with Hodgkin features | Full Text | References | PDF (1.5 MB) | EPUB
  • 195 Views
  • 1 CrossRef citations
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Dismal survival outcomes of patients with acute myeloid leukemia after failure of venetoclax with hypomethylating agents
Carl Zainaldin, Sankalp Arora, Srilakshmi Bathini, Udita Gupta, Vishruti Pandya, Sejong Bae, Sarah Worth, Kimo Bachiashvili, Ravi Bhatia, Kelly Godby, Omer Jamy, Sravanti Rangaraju, Barry Diamond, Josh D. Oliver, Donna Salzman, Antonio Di Stasi & Pankit Vachhani
Pages: 3245-3248
Published online: 15 Sep 2022
First Page PreviewforDismal survival outcomes of patients with acute myeloid leukemia after failure of venetoclax with hypomethylating agents | Full Text | References | PDF (666 KB) | EPUB
  • 233 Views
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Denosumab versus intravenous bisphosphonate use for hypercalcemia in multiple myeloma
Matthew M. Lei, Erica Tavares, Evan Buzgo, Uvette Lou, Noopur Raje & Andrew J. Yee
Pages: 3249-3252
Published online: 29 Aug 2022
First Page PreviewforDenosumab versus intravenous bisphosphonate use for hypercalcemia in multiple myeloma | Full Text | References | PDF (681.6 KB) | EPUB
  • 537 Views
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Exploration of whole genome and transcriptome sequencing data lacks evidence for oncogenic viral elements to drive the pathogenesis of T-cell prolymphocytic leukemia
Paurnima Patil, Umut H. Toprak, Julian Seufert, Till Braun, Stephan H. Bernhart, Laura Wiehle, Annika Müller, Matthias Schlesner, Marco Herling, Peter Lichter, Stephan Stilgenbauer, Reiner Siebert & Marc Zapatka
Pages: 3253-3256
Published online: 09 Sep 2022
First Page PreviewforExploration of whole genome and transcriptome sequencing data lacks evidence for oncogenic viral elements to drive the pathogenesis of T-cell prolymphocytic leukemia | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 1070 Views
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Open Access
A nomogram using cytogenetics, TP53, and NPM1 mutational status can predict responses to induction chemotherapy in AML
Konstantinos Lontos, Anastasia Tsagianni, Mounzer Agha, Anastasios Raptis, Jing-Zhou Hou, Rafic Farah, Robert L. Redner, Annie Im, Kathleen A. Dorritie, Alison Sehgal, James Rossetti, Nidhi Aggarwal, Melissa Saul, William Gooding & Michael Boyiadzis
Pages: 3257-3260
Published online: 08 Sep 2022
First Page PreviewforA nomogram using cytogenetics, TP53, and NPM1 mutational status can predict responses to induction chemotherapy in AML | Full Text | References | PDF (793.9 KB) | EPUB | Supplemental
  • 156 Views
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Labile CD22 and CD19 expression in a case of Philadelphia chromosome-like acute lymphoblastic leukemia
Junichi Mukae, Daichi Sadato, Takashi Toya, Satoru Watanabe, Chizuko Hirama, Ryosuke Konuma, Hiroaki Shimizu, Yuho Najima, Takeshi Kobayashi, Motohiro Kato, Kentaro Ohki, Keisuke Oboki, Hironori Harada, Kazuteru Ohashi, Takao Deguchi, Yuka Harada & Noriko Doki
Pages: 3261-3264
Published online: 14 Sep 2022
First Page PreviewforLabile CD22 and CD19 expression in a case of Philadelphia chromosome-like acute lymphoblastic leukemia | Full Text | References | PDF (1,002 KB) | EPUB | Supplemental
  • 119 Views
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Successful provision of CAR-T therapy during a pandemic: low SARS-CoV-2 infection rates and reduction in ICU admissions following modification of patient pathway
Luke Carter-Brzezinski, Elizabeth Davies, Jane Norman, Lourdes Rubio, Christopher Dixon, Sarah Brett, Tony Dunne, Shahid Iqbal, Fiona L. Dignan, Shazaad Ahmad, Nicholas Machin, Henry Morriss, Anthony Wilson & Eleni Tholouli
Pages: 3265-3267
Published online: 22 Aug 2022
First Page PreviewforSuccessful provision of CAR-T therapy during a pandemic: low SARS-CoV-2 infection rates and reduction in ICU admissions following modification of patient pathway | Full Text | References | PDF (466.5 KB) | EPUB | Supplemental
  • 141 Views
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Inotuzumab ozogamicin is deliverable in relapsed ALL patients with end-stage renal disease on hemodialysis
Idoroenyi Amanam, Dat Ngo, Vinod Pullarkat & Ibrahim Aldoss
Pages: 3268-3270
Published online: 25 Aug 2022
First Page PreviewforInotuzumab ozogamicin is deliverable in relapsed ALL patients with end-stage renal disease on hemodialysis | Full Text | References | PDF (614.9 KB) | EPUB
  • 192 Views
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