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Research Articles

Pathophysiological and vascular characteristics of tumours and their importance for hyperthermia: Heterogeneity is the key issue

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Pages 211-223 | Received 14 Dec 2009, Accepted 04 Jan 2010, Published online: 26 Mar 2010

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H. P. Kok, G. C. van Rhoon, T. D. Herrera, J. Overgaard & J. Crezee. (2022) Biological modeling in thermoradiotherapy: present status and ongoing developments toward routine clinical use. International Journal of Hyperthermia 39:1, pages 1126-1140.
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Lukas Christian Sebeke, Pia Rademann, Alexandra Claudia Maul, Sin Yuin Yeo, Juan Daniel Castillo Gómez, Daniel A. Deenen, Patrick Schmidt, Bram de Jager, W. P. M. H. Heemels, Holger Grüll & Edwin Heijman. (2021) Visualization of thermal washout due to spatiotemporally heterogenous perfusion in the application of a model-based control algorithm for MR-HIFU mediated hyperthermia. International Journal of Hyperthermia 38:1, pages 1174-1187.
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Pernille B. Elming, Brita S. Sørensen, Harald Spejlborg, Jens Overgaard & Michael R. Horsman. (2021) Does the combination of hyperthermia with low LET (linear energy transfer) radiation induce anti-tumor effects equivalent to those seen with high LET radiation alone?. International Journal of Hyperthermia 38:1, pages 105-110.
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Sara Gouarderes, Anne-Françoise Mingotaud, Patricia Vicendo & Laure Gibot. (2020) Vascular and extracellular matrix remodeling by physical approaches to improve drug delivery at the tumor site. Expert Opinion on Drug Delivery 17:12, pages 1703-1726.
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Fatemeh Adibzadeh, Kemal Sumser, Sergio Curto, Desmond T. B. Yeo, Amir A. Shishegar & Margarethus M. Paulides. (2020) Systematic review of pre-clinical and clinical devices for magnetic resonance-guided radiofrequency hyperthermia. International Journal of Hyperthermia 37:1, pages 15-27.
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Shin-ichiro Masunaga, Yoshinori Sakurai, Hiroki Tanaka, Takushi Takata, Minoru Suzuki, Yu Sanada, Keizo Tano, Akira Maruhashi & Koji Ono. (2019) Usefulness of combination with both continuous administration of hypoxic cytotoxin and mild temperature hyperthermia in boron neutron capture therapy in terms of local tumor response and lung metastatic potential. International Journal of Radiation Biology 95:12, pages 1708-1717.
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Niloy Ranjan Datta & Stephan Bodis. (2019) Hyperthermia with photon radiotherapy is thermoradiobiologically analogous to neutrons for tumors without enhanced normal tissue toxicity. International Journal of Hyperthermia 36:1, pages 1072-1077.
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A. L. Oei, L. E. M. Vriend, P. M. Krawczyk, M. R. Horsman, N. A. P. Franken & J. Crezee. (2017) Targeting therapy-resistant cancer stem cells by hyperthermia. International Journal of Hyperthermia 33:4, pages 419-427.
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Yannan Nancy Dou, Michael Dunne, Huang Huang, Trevor Mckee, Martin C. Chang, David A. Jaffray & Christine Allen. (2016) Thermosensitive liposomal cisplatin in combination with local hyperthermia results in tumor growth delay and changes in tumor microenvironment in xenograft models of lung carcinoma*. Journal of Drug Targeting 24:9, pages 865-877.
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Gerard C. van Rhoon. (2016) Is CEM43 still a relevant thermal dose parameter for hyperthermia treatment monitoring?. International Journal of Hyperthermia 32:1, pages 50-62.
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Ana Portela, Mário Vasconcelos, Maria Helena Fernandes, Mónica Garcia, António Silva, Joaquim Gabriel, Fátima Gartner, Irina Amorim & José Cavalheiro. (2013) Highly focalised thermotherapy using a ferrimagnetic cement in the treatment of a melanoma mouse model by low temperature hyperthermia. International Journal of Hyperthermia 29:2, pages 121-132.
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Shin-Ichiro Masunaga, Yong Liu, Yoshinori Sakurai, Hiroki Tanaka, Minoru Suzuki, Natsuko Kondo, Akira Maruhashi & Koji Ono. (2012) Usefulness of combined treatment with continuous administration of tirapazamine and mild temperature hyperthermia in γ-ray irradiation in terms of local tumour response and lung metastatic potential. International Journal of Hyperthermia 28:7, pages 636-644.
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Peter W. Vaupel & Debra K. Kelleher. (2012) Blood flow and associated pathophysiology of uterine cervix cancers: Characterisation and relevance for localised hyperthermia. International Journal of Hyperthermia 28:6, pages 518-527.
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Fatemeh Haji Ghahremani, Ameneh Sazgarnia, Mohammad Hossein Bahreyni-Toosi, Omid Rajabi & Amir Aledavood. (2011) Efficacy of microwave hyperthermia and chemotherapy in the presence of gold nanoparticles: An in vitro study on osteosarcoma. International Journal of Hyperthermia 27:6, pages 625-636.
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Min Kyu Kang, Myung Se Kim & Jae Hwang Kim. (2011) Clinical outcomes of mild hyperthermia for locally advanced rectal cancer treated with preoperative radiochemotherapy. International Journal of Hyperthermia 27:5, pages 482-490.
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Florian Grabellus, Lars E. Podleska, Saturnina Bjerlestam, Sien-Yi Sheu, Sven Lendemans, Kurt W. Schmid & Georg Taeger. (2011) Increased shedding of soluble TNF-receptor 1 during hyperthermic TNF-α-based isolated limb perfusion. International Journal of Hyperthermia 27:1, pages 33-41.
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