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Research Articles

Hyperthermia-induced DNA repair deficiency suggests novel therapeutic anti-cancer strategies

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Pages 509-517 | Received 07 Feb 2012, Accepted 15 May 2012, Published online: 26 Jul 2012

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H. P. Kok, G. C. van Rhoon, T. D. Herrera, J. Overgaard & J. Crezee. (2022) Biological modeling in thermoradiotherapy: present status and ongoing developments toward routine clinical use. International Journal of Hyperthermia 39:1, pages 1126-1140.
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Lukas Christian Sebeke, Pia Rademann, Alexandra Claudia Maul, Sin Yuin Yeo, Juan Daniel Castillo Gómez, Daniel A. Deenen, Patrick Schmidt, Bram de Jager, W. P. M. H. Heemels, Holger Grüll & Edwin Heijman. (2021) Visualization of thermal washout due to spatiotemporally heterogenous perfusion in the application of a model-based control algorithm for MR-HIFU mediated hyperthermia. International Journal of Hyperthermia 38:1, pages 1174-1187.
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Elles A. L. Raaijmakers, Rob M. C. Mestrom, K. Sumser, Ghassan Salim, Gerard C. van Rhoon, Jeroen Essers & Margarethus M. Paulides. (2018) An MR-compatible antenna and application in a murine superficial hyperthermia applicator. International Journal of Hyperthermia 34:6, pages 697-703.
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Nathalie van den Tempel, Hanny Odijk, Netteke van Holthe, Kishan Naipal, Anja Raams, Berina Eppink, Dik C. van Gent, Jose Hardillo, Gerda M. Verduijn, Jan C. Drooger, Gerard C. van Rhoon, Dineke (H.) P.M. Smedts, Helena C. van Doorn, Joost L. Boormans, Agnes Jager, Martine Franckena & Roland Kanaar. (2018) Heat-induced BRCA2 degradation in human tumours provides rationale for hyperthermia-PARP-inhibitor combination therapies. International Journal of Hyperthermia 34:4, pages 407-414.
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Arlene L. Oei, Vidhula R. Ahire, C. M. van Leeuwen, Rosemarie ten Cate, Lukas J. A. Stalpers, Johannes Crezee, H. Petra Kok & Nicolaas A. P. Franken. (2018) Enhancing radiosensitisation of BRCA2-proficient and BRCA2-deficient cell lines with hyperthermia and PARP1-i. International Journal of Hyperthermia 34:1, pages 39-48.
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H. P. Kok, A. N. T. J. Kotte & J. Crezee. (2017) Planning, optimisation and evaluation of hyperthermia treatments. International Journal of Hyperthermia 33:6, pages 593-607.
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A. L. Oei, L. E. M. Vriend, P. M. Krawczyk, M. R. Horsman, N. A. P. Franken & J. Crezee. (2017) Targeting therapy-resistant cancer stem cells by hyperthermia. International Journal of Hyperthermia 33:4, pages 419-427.
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Yoko Harima, Takayuki Ohguri, Hajime Imada, Hideyuki Sakurai, Tatsuya Ohno, Yoshiyuki Hiraki, Koh Tuji, Masahiro Tanaka & Hiromi Terashima. (2016) A multicentre randomised clinical trial of chemoradiotherapy plus hyperthermia versus chemoradiotherapy alone in patients with locally advanced cervical cancer. International Journal of Hyperthermia 32:7, pages 801-808.
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Nathalie van den Tempel, Michael R. Horsman & Roland Kanaar. (2016) Improving efficacy of hyperthermia in oncology by exploiting biological mechanisms. International Journal of Hyperthermia 32:4, pages 446-454.
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Francesco Soria, Marco Allasia, Marco Oderda & Paolo Gontero. (2016) Hyperthermia for non-muscle invasive bladder cancer. Expert Review of Anticancer Therapy 16:3, pages 313-321.
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Rolf Issels, Eric Kampmann, Roland Kanaar & Lars H. Lindner. (2016) Hallmarks of hyperthermia in driving the future of clinical hyperthermia as targeted therapy: translation into clinical application. International Journal of Hyperthermia 32:1, pages 89-95.
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Gerard C. van Rhoon. (2016) Is CEM43 still a relevant thermal dose parameter for hyperthermia treatment monitoring?. International Journal of Hyperthermia 32:1, pages 50-62.
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Hans Crezee, Caspar M. van Leeuwen, Arlene L. Oei, Lukas J.A. Stalpers, Arjan Bel, Nicolaas A. Franken & H. Petra Kok. (2016) Thermoradiotherapy planning: Integration in routine clinical practice. International Journal of Hyperthermia 32:1, pages 41-49.
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Michael R. Horsman. (2016) Realistic biological approaches for improving thermoradiotherapy. International Journal of Hyperthermia 32:1, pages 14-22.
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Mayra L. Sottile, Antonella D. Losinno, Mariel A. Fanelli, F. Darío Cuello-Carrión, M. Magdalena Montt-Guevara, Laura M. Vargas-Roig & Silvina B. Nadin. (2015) Hyperthermia effects on Hsp27 and Hsp72 associations with mismatch repair (MMR) proteins and cisplatin toxicity in MMR-deficient/proficient colon cancer cell lines. International Journal of Hyperthermia 31:5, pages 464-475.
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Vladimir V. Kosterev, Evgeny A. Kramer-Ageev, Vladimir N. Mazokhin, Gerard C. van Rhoon & Johannes Crezee. (2015) Development of a novel method to enhance the therapeutic effect on tumours by simultaneous action of radiation and heating. International Journal of Hyperthermia 31:4, pages 443-452.
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Imen Belhadj Slimen, Taha Najar, Abdeljelil Ghram, Hajer Dabbebi, Moncef Ben Mrad & Manef Abdrabbah. (2014) Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review. International Journal of Hyperthermia 30:7, pages 513-523.
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João FS Carvalho & Roland Kanaar. (2014) Targeting homologous recombination-mediated DNA repair in cancer. Expert Opinion on Therapeutic Targets 18:4, pages 427-458.
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Makoto Ihara, Satoshi Takeshita, Kumio Okaichi, Yutaka Okumura & Takeo Ohnishi. (2014) Heat exposure enhances radiosensitivity by depressing DNA-PK kinase activity during double strand break repair. International Journal of Hyperthermia 30:2, pages 102-109.
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Bilyana M Dicheva & Gerben A Koning. (2014) Targeted thermosensitive liposomes: an attractive novel approach for increased drug delivery to solid tumors. Expert Opinion on Drug Delivery 11:1, pages 83-100.
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Zef Rijnen, Jurriaan F. Bakker, Richard A.M. Canters, Paolo Togni, Gerda M. Verduijn, Peter C. Levendag, Gerard C. Van Rhoon & Margarethus M. Paulides. (2013) Clinical integration of software tool VEDO for adaptive and quantitative application of phased array hyperthermia in the head and neck. International Journal of Hyperthermia 29:3, pages 181-193.
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Deng-Hai Mi, Zheng Li, Ke-Hu Yang, Nong Cao, Anne Lethaby, Jin-Hui Tian, Nancy Santesso, Bin Ma, Yao-Long Chen & Ya-Li Liu. (2013) Surgery combined with intraoperative hyperthermic intraperitoneal chemotherapy (IHIC) for gastric cancer: A systematic review and meta-analysis of randomised controlled trials. International Journal of Hyperthermia 29:2, pages 156-167.
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Jacoba van der Zee & Martine Franckena. (2012) Editorial. International Journal of Hyperthermia 28:6, pages 475-477.
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