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Research Article

Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase, and butyrylcholinesterase

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Pages 1498-1501 | Received 07 Jan 2016, Accepted 29 Jan 2016, Published online: 01 Mar 2016

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Mansura Huseynova, Ajdar Medjidov, Parham Taslimi & Mahizar Aliyeva. (2019) Synthesis, characterization, crystal structure of the coordination polymer Zn(II) with thiosemicarbazone of glyoxalic acid and their inhibitory properties against some metabolic enzymes. Bioorganic Chemistry 83, pages 55-62.
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Adnan Cetin, Fikret Türkan, Parham Taslimi & İlhami Gulçin. (2018) Synthesis and characterization of novel substituted thiophene derivatives and discovery of their carbonic anhydrase and acetylcholinesterase inhibition effects. Journal of Biochemical and Molecular Toxicology 33:3.
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Cuneyt Caglayan, Yeliz Demir, Sefa Kucukler, Parham Taslimi, Fatih Mehmet Kandemir & İlhami Gulçin. (2019) The effects of hesperidin on sodium arsenite-induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: A biochemical approach. Journal of Food Biochemistry 43:2, pages e12720.
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Abdullah Biçer, Parham Taslimi, Gül Yakalı, Ilhami Gülçin, Mehmet Serdar Gültekin & Günseli Turgut Cin. (2019) Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes. Bioorganic Chemistry 82, pages 393-404.
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Emre Güzel, Ümit M. Koçyiğit, Barış S. Arslan, Mehmet Ataş, Parham Taslimi, Faik Gökalp, Mehmet Nebioğlu, İlkay Şişman & İlhami Gulçin. (2019) Aminopyrazole‐substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties. Archiv der Pharmazie 352:2.
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Salih Ökten, Makbule Ekiz, Ümit Muhammet Koçyiğit, Ahmet Tutar, İsmail Çelik, Mehmet Akkurt, Faik Gökalp, Parham Taslimi & İlhami Gülçin. (2019) Synthesis, characterization, crystal structures, theoretical calculations and biological evaluations of novel substituted tacrine derivatives as cholinesterase and carbonic anhydrase enzymes inhibitors. Journal of Molecular Structure 1175, pages 906-915.
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Mehtap Tugrak, Halise Inci Gul, Hiroshi Sakagami, Ilhami Gulcin & Claudiu T. Supuran. (2018) New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones. Bioorganic Chemistry 81, pages 433-439.
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Mustafa Zengin, Hayriye Genc, Parham Taslimi, Ali Kestane, Ertugrul Guclu, Aziz Ogutlu, Oguz Karabay & İlhami Gulçin. (2018) Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors – Their antidiabetic, anticholinergic and antibacterial potentials. Bioorganic Chemistry 81, pages 119-126.
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Reuel de Paula, Joyce de Almeida, Samir Cavalcante, Arlan Gonçalves, Alessandro Simas, Tanos Franca, Martin Valis, Kamil Kuca, Eugenie Nepovimova & José Granjeiro. (2018) Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon. Molecules 23:11, pages 2954.
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Gulnar Gondolova, Parham Taslimi, Ajdar Medjidov, Vagif Farzaliyev, Afsun Sujayev, Mansura Huseynova, Onur Şahin, Bahattin Yalçın, Fikret Turkan & İlhami Gulçin. (2018) Synthesis, crystal structure and biological evaluation of spectroscopic characterization of Ni(II) and Co(II) complexes with N -salicyloil- N ′-maleoil-hydrazine as anticholinergic and antidiabetic agents . Journal of Biochemical and Molecular Toxicology 32:9, pages e22197.
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Parham Taslimi, Sabiya Osmanova, Cuneyt Caglayan, Fikret Turkan, Sabira Sardarova, Vagif Farzaliyev, Afsun Sujayev, Nastaran Sadeghian & İlhami Gulçin. (2018) Novel amides of 1,1-bis-(carboxymethylthio)-1-arylethanes: Synthesis, characterization, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibitory properties. Journal of Biochemical and Molecular Toxicology 32:9, pages e22191.
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Kadir Aksu, Hülya Akıncıoğlu, Akın Akıncıoğlu, Süleyman Göksu, Ferhan Tümer & İlhami Gülçin. (2018) Synthesis of novel sulfamides incorporating phenethylamines and determination of their inhibition profiles against some metabolic enzymes. Archiv der Pharmazie 351:9, pages 1800150.
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Beyhan Yiğit, Murat Yiğit, Parham Taslimi, Yetkin Gök & İlhami Gülçin. (2018) Schiff bases and their amines: Synthesis and discovery of carbonic anhydrase and acetylcholinesterase enzymes inhibitors. Archiv der Pharmazie 351:9, pages 1800146.
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Ufuk Atmaca, Alper Yıldırım, Parham Taslimi, Seda Tuncel Çelik, İlhami Gülçin, Claudiu T. Supuran & Murat Çelik. (2018) Intermolecular amination of allylic and benzylic alcohols leads to effective inhibitions of acetylcholinesterase enzyme and carbonic anhydrase I and II isoenzymes. Journal of Biochemical and Molecular Toxicology 32:8, pages e22173.
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Umit M. Kocyigit, Parham Taslimi & İlhami Gulçin. (2018) Characterization and inhibition effects of some metal ions on carbonic anhydrase enzyme from Kangal Akkaraman sheep. Journal of Biochemical and Molecular Toxicology 32:8, pages e22172.
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Cem Yamali, Halise Inci Gul, Abdulilah Ece, Parham Taslimi & Ilhami Gulcin. (2018) Synthesis, molecular modeling, and biological evaluation of 4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1 H -pyrazol-1-yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes . Chemical Biology & Drug Design 91:4, pages 854-866.
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Fatoş Erdemir, Duygu Barut Celepci, Aydın Aktaş, Parham Taslimi, Yetkin Gök, Hasan Karabıyık & İlhami Gülçin. (2018) 2-Hydroxyethyl substituted NHC precursors: Synthesis, characterization, crystal structure and carbonic anhydrase, α-glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties. Journal of Molecular Structure 1155, pages 797-806.
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Fikret Türkan, Zübeyir Huyut, Parham Taslimi & İlhami Gülçin. (2018) The in vivo effects of cefazolin, cefuroxime, and cefoperazon on the carbonic anhydrase in different rat tissues . Journal of Biochemical and Molecular Toxicology 32:3, pages e22041.
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A. V. Bogdanov, A. R. Gil’fanova, I. F. Zaripova & V. F. Mironov. (2018) Features of Reactions of Some 1-Arylaminomethylisatins with Girard’s Reagent T. Russian Journal of General Chemistry 88:1, pages 124-126.
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Yakup Sarı, Aydın Aktaş, Parham Taslimi, Yetkin Gök & İlhami Gulçin. (2018) Novel N -propylphthalimide- and 4-vinylbenzyl-substituted benzimidazole salts: Synthesis, characterization, and determination of their metal chelating effects and inhibition profiles against acetylcholinesterase and carbonic anhydrase enzymes . Journal of Biochemical and Molecular Toxicology 32:1, pages e22009.
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Nilufer Bulut, Umit M. Kocyigit, Ibrahim H. Gecibesler, Taner Dastan, Huseyin Karci, Parham Taslimi, Sevgi Durna Dastan, Ilhami Gulcin & Ahmet Cetin. (2018) Synthesis of some novel pyridine compounds containing bis-1,2,4-triazole/thiosemicarbazide moiety and investigation of their antioxidant properties, carbonic anhydrase, and acetylcholinesterase enzymes inhibition profiles. Journal of Biochemical and Molecular Toxicology 32:1, pages e22006.
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Ümit M. Koçyiğit, Sevgi Durna Daştan, Parham Taslimi, Taner Daştan & İlhami Gülçin. (2018) Inhibitory effects of some drugs on carbonic anhydrase enzyme purified from Kangal Akkaraman sheep in Sivas, Turkey. Journal of Biochemical and Molecular Toxicology 32:1, pages e22000.
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Parham Taslimi, Cuneyt Caglayan & İlhami Gulcin. (2017) The impact of some natural phenolic compounds on carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes: An antidiabetic, anticholinergic, and antiepileptic study. Journal of Biochemical and Molecular Toxicology 31:12, pages e21995.
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Umit M. Kocyigit, Yakup Budak, Fikret Eligüzel, Parham Taslimi, Deryanur Kılıç, İlhami Gulçin & Mustafa Ceylan. (2017) Synthesis and Carbonic Anhydrase Inhibition of Tetrabromo Chalcone Derivatives. Archiv der Pharmazie 350:12, pages 1700198.
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Taner Dastan, Umit M. Kocyigit, Sevgi Durna Dastan, Pakize Canturk Kilickaya, Parham Taslimi, Ozge Cevik, Metin Koparir, Cahit Orek, İlhami Gulçin & Ahmet Cetin. (2017) Investigation of acetylcholinesterase and mammalian DNA topoisomerases, carbonic anhydrase inhibition profiles, and cytotoxic activity of novel bis(α‐aminoalkyl)phosphinic acid derivatives against human breast cancer. Journal of Biochemical and Molecular Toxicology 31:11.
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Akın Akıncıoğlu, Ebutalib Kocaman, Hülya Akıncıoğlu, Ramin Ekhteiari Salmas, Serdar Durdagi, İlhami Gülçin, Claudiu T. Supuran & Süleyman Göksu. (2017) The synthesis of novel sulfamides derived from β-benzylphenethylamines as acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase enzymes inhibitors. Bioorganic Chemistry 74, pages 238-250.
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Zeynep Köksal, Ramazan Kalın, Serpil Gerni, İlhami Gülçin & Hasan Özdemir. (2017) The inhibition effects of some natural products on lactoperoxidase purified from bovine milk. Journal of Biochemical and Molecular Toxicology 31:9, pages e21939.
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Umit M. Kocyigit, Parham Taslimi, Hayreddin Gezegen, İlhami Gulçin & Mustafa Ceylan. (2017) Evaluation of acetylcholinesterase and carbonic anhydrase inhibition profiles of 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes. Journal of Biochemical and Molecular Toxicology 31:9, pages e21938.
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Parham Taslimi, Sabiya Osmanova, İlhami Gulçin, Sabira Sardarova, Vagif Farzaliyev, Afsun Sujayev, Ruya Kaya, Fatma Koc, Sukru Beydemir, Saleh H. Alwasel & Omer Irfan Kufrevioglu. (2017) Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base. Journal of Biochemical and Molecular Toxicology 31:9, pages e21931.
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Parham Taslimi, Afsun Sujayev, Emin Garibov, Nazar Nazarov, Zubeyir Huyut, Saleh H. Alwasel & İlhami Gulçin. (2017) Synthesis of new cyclic thioureas and evaluation of their metal-chelating activity, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibition profiles. Journal of Biochemical and Molecular Toxicology 31:7, pages e21897.
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Çetin Bayrak, Parham Taslimi, İlhami Gülçin & Abdullah Menzek. (2017) The first synthesis of 4-phenylbutenone derivative bromophenols including natural products and their inhibition profiles for carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase enzymes. Bioorganic Chemistry 72, pages 359-366.
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Aydın Aktaş, Parham Taslimi, İlhami Gülçin & Yetkin Gök. (2017) Novel NHC Precursors: Synthesis, Characterization, and Carbonic Anhydrase and Acetylcholinesterase Inhibitory Properties. Archiv der Pharmazie 350:6, pages e201700045.
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Umit M. Kocyigit, Yakup Budak, Meliha Burcu Gürdere, Şaban Tekin, Tuğba Kul Köprülü, Fatih Ertürk, Kezban Özcan, İlhami Gülçin & Mustafa Ceylan. (2017) Synthesis, characterization, anticancer, antimicrobial and carbonic anhydrase inhibition profiles of novel (3a R ,4 S ,7 R ,7a S )-2-(4-(( E )-3-(3-aryl)acryloyl) phenyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione derivatives. Bioorganic Chemistry 70, pages 118-125.
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