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Review

The ULK1 complex

Sensing nutrient signals for autophagy activation

, , &
Pages 124-137 | Received 07 Sep 2012, Accepted 18 Dec 2012, Published online: 07 Jan 2013

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Jianqiang Liang, Lin Zhang & Wenjun Cheng. (2021) Non-coding RNA-mediated autophagy in cancer: A protumor or antitumor factor?. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1876:2, pages 188642.
Crossref
Amanda J. Manea & Swapan K. Ray. (2021) Regulation of autophagy as a therapeutic option in glioblastoma. Apoptosis 26:11-12, pages 574-599.
Crossref
Yuchen Lei & Daniel J. Klionsky. (2021) The Emerging Roles of Autophagy in Human Diseases. Biomedicines 9:11, pages 1651.
Crossref
Sachiko Miyamoto, Mitsuhiro Kato, Takuya Hiraide, Tadashi Shiohama, Tomohide Goto, Akira Hojo, Akio Ebata, Manabu Suzuki, Kozue Kobayashi, Pin Fee Chong, Ryutaro Kira, Hiroko Baber Matsushita, Hiroko Ikeda, Kyoko Hoshino, Mayumi Matsufuji, Nobuko Moriyama, Masayuki Furuyama, Tatsuya Yamamoto, Mitsuko Nakashima & Hirotomo Saitsu. (2021) Comprehensive genetic analysis confers high diagnostic yield in 16 Japanese patients with corpus callosum anomalies. Journal of Human Genetics 66:11, pages 1061-1068.
Crossref
Eleanor C. Warren, Pavol Kramár, Katie Lloyd-Jones & Robin S. B. Williams. (2021) Decanoic Acid Stimulates Autophagy in D. discoideum. Cells 10:11, pages 2946.
Crossref
Sabino Russi, Alessandro Sgambato, Anna Maria Bochicchio, Pietro Zoppoli, Michele Aieta, Alba Maria Lucia Capobianco, Vitalba Ruggieri, Emanuela Zifarone, Geppino Falco & Simona Laurino. (2021) CHIR99021, trough GSK-3β Targeting, Reduces Epithelioid Sarcoma Cell Proliferation by Activating Mitotic Catastrophe and Autophagy. International Journal of Molecular Sciences 22:20, pages 11147.
Crossref
Kai Zhang, Shiou Zhu, Jiamei Li, Tingting Jiang, Lu Feng, Junping Pei, Guan Wang, Liang Ouyang & Bo Liu. (2021) Targeting autophagy using small-molecule compounds to improve potential therapy of Parkinson's disease. Acta Pharmaceutica Sinica B 11:10, pages 3015-3034.
Crossref
Charles B. Trelford & Gianni M. Di Guglielmo. (2021) Molecular mechanisms of mammalian autophagy. Biochemical Journal 478:18, pages 3395-3421.
Crossref
Zi Li, Feng Gao, Yungang Lan, Jiyu Guan, Jing Zhang, Huijun Lu, Kui Zhao & Wenqi He. (2021) Porcine Hemagglutinating Encephalomyelitis Virus Triggers Neural Autophagy Independently of ULK1. Journal of Virology 95:19.
Crossref
Thuy T.P. Nguyen, Do-Young Kim, Yu-Geon Lee, Young-Seung Lee, Xuan T. Truong, Jae-Ho Lee, Dae-Kyu Song, Taeg Kyu Kwon, So-Hyun Park, Chang Hwa Jung, Changjong Moon, Timothy F. Osborne, Seung-Soon Im & Tae-Il Jeon. (2021) SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice. Molecular Cell 81:18, pages 3820-3832.e7.
Crossref
Sebastian Mathea, Eidarus SalahCynthia TallantDeep Chatterjee, Benedict-Tilman Berger, Rebecca KonietznySusanne Müller, Benedikt M. KesslerStefan Knapp. (2021) Conformational plasticity of the ULK3 kinase domain. Biochemical Journal 478:14, pages 2811-2823.
Crossref
Neha Sharma, Mohd Shariq, Neha Quadir, Jasdeep Singh, Javaid A. Sheikh, Seyed E. Hasnain & Nasreen Z. Ehtesham. (2021) Mycobacterium tuberculosis Protein PE6 (Rv0335c), a Novel TLR4 Agonist, Evokes an Inflammatory Response and Modulates the Cell Death Pathways in Macrophages to Enhance Intracellular Survival. Frontiers in Immunology 12.
Crossref
Mohd Mohsin, Gulnaz Tabassum, Shaniya Ahmad, Shakir Ali & Mansoor Ali Syed. (2021) The role of mitophagy in pulmonary sepsis. Mitochondrion 59, pages 63-75.
Crossref
Diego Sbardella, Grazia Raffaella Tundo, Massimo Coletta, Gianluca Manni & Francesco Oddone. (2021) Dexamethasone Downregulates Autophagy through Accelerated Turn-Over of the Ulk-1 Complex in a Trabecular Meshwork Cells Strain: Insights on Steroid-Induced Glaucoma Pathogenesis. International Journal of Molecular Sciences 22:11, pages 5891.
Crossref
Hao Zhang, Xiaoyun Liu, Yaotian Fan, Yin Yu, Juan J Loor, Juan J Loor, Along Peng & Hongrong Wang. (2021) l-Arginine Alleviates Hydrogen Peroxide–Induced Oxidative Damage in Ovine Intestinal Epithelial Cells by Regulating Apoptosis, Mitochondrial Function, and Autophagy. The Journal of Nutrition 151:4, pages 1038-1046.
Crossref
Yu-Lin Guo, Wen-Jun Duan, Dan-Hua Lu, Xiao-Hui Ma, Xiao-Xiao Li, Zhao Li, Wei Bi, Hiroshi Kurihara, Hai-Zhi Liu, Yi-Fang Li & Rong-Rong He. (2020) Autophagy-dependent removal of α-synuclein: a novel mechanism of GM1 ganglioside neuroprotection against Parkinson’s disease. Acta Pharmacologica Sinica 42:4, pages 518-528.
Crossref
Qiaoyun Gong, Haiyan Wang, Ping Yu, Tianwei Qian & Xun Xu. (2021) Protective or Harmful: The Dual Roles of Autophagy in Diabetic Retinopathy. Frontiers in Medicine 8.
Crossref
Guan-Man Li, Lei Li, Meng-Qing Li, Xu Chen, Qiao Su, Zhi-Juan Deng, Hai-Bo Liu, Bin Li, Wen-Hui Zhang, Yong-Xu Jia, Wen-Jian Wang, Jie-Yi Ma, Hai-Liang Zhang, Dan Xie, Xiao-Feng Zhu, Yu-Long He, Xin-Yuan Guan & Jiong Bi. (2020) DAPK3 inhibits gastric cancer progression via activation of ULK1-dependent autophagy. Cell Death & Differentiation 28:3, pages 952-967.
Crossref
Hye Young Ryu, Leah Eunjung Kim, Hyeonjeong Jeong, Bo Kyoung Yeo, Ji-Won Lee, Hyeri Nam, Shinwon Ha, Hyun-Kyu An, Hyunhee Park, Seonghee Jung, Kyung Min Chung, Jiyea Kim, Byung-Hoon Lee, Heesun Cheong, Eun-Kyoung Kim & Seong-Woon Yu. (2021) GSK3B induces autophagy by phosphorylating ULK1. Experimental & Molecular Medicine 53:3, pages 369-383.
Crossref
Jing Zhuang, Xiaoyue Ji, Yue Zhu, Wei Liu, Jing Sun, Xinan Jiao & Xiulong Xu. (2021) Restriction of intracellular Salmonella typhimurium growth by the small-molecule autophagy inducer A77 1726 through the activation of the AMPK-ULK1 axis. Veterinary Microbiology 254, pages 108982.
Crossref
Bor Luen Tang. (2020) RAB39B's role in membrane traffic, autophagy, and associated neuropathology. Journal of Cellular Physiology 236:3, pages 1579-1592.
Crossref
Camille Sena-dos-Santos, Cíntia Braga-da-Silva, Diego Marques, Jhully Azevedo dos Santos Pinheiro, Ândrea Ribeiro-dos-Santos & Giovanna C. Cavalcante. (2021) Unraveling Cell Death Pathways during Malaria Infection: What Do We Know So Far?. Cells 10:2, pages 479.
Crossref
Manuela Morleo, Simona Brillante, Umberto Formisano, Luigi Ferrante, Fabrizia Carbone, Daniela Iaconis, Alessandro Palma, Viviana Buonomo, Angela Serena Maione, Paolo Grumati, Carmine Settembre & Brunella Franco. (2020) Regulation of autophagosome biogenesis by OFD1‐mediated selective autophagy. The EMBO Journal 40:4.
Crossref
Siyu He, Yang Liu, Qihang Li, Weiping Lyu, Feng Feng, Qinglong Guo, Li Zhao & Haopeng Sun. (2021) In silico approaches using pharmacophore model combined with molecular docking for discovery of novel ULK1 inhibitors . Future Medicinal Chemistry 13:4, pages 341-361.
Crossref
Ainhoa Plaza-Zabala, Virginia Sierra-Torre & Amanda Sierra. (2021) Assessing Autophagy in Microglia: A Two-Step Model to Determine Autophagosome Formation, Degradation, and Net Turnover. Frontiers in Immunology 11.
Crossref
Francesca Castoldi & Federico Pietrocola. 2021. Non-Canonical Autophagy. Non-Canonical Autophagy 133 165 .
Mohammad Nasb, Michael Kirberger & Ning Chen. 2021. Exercise, Autophagy and Chronic Diseases. Exercise, Autophagy and Chronic Diseases 1 27 .
Ivanka Jimenez, Yolanda Prado, Felipe Marchant, Carolina Otero, Felipe Eltit, Claudio Cabello-Verrugio, Oscar Cerda & Felipe Simon. (2020) TRPM Channels in Human Diseases. Cells 9:12, pages 2604.
Crossref
К.Г. Лямзаев, Д.А. Кнорре & Б.В. Черняк. (2020) Митоптоз, двадцать лет спустя. Биохимия 85:12, pages 1750-1765.
Crossref
Mohammad Hossein Pourhanifeh, Maryam Mahjoubin-Tehran, Mohammad Reza Karimzadeh, Hamid Reza Mirzaei, Zahra Sadat Razavi, Amirhossein Sahebkar, Nayyerehsadat Hosseini, Hamed Mirzaei & Michael R. Hamblin. (2020) Autophagy in cancers including brain tumors: role of MicroRNAs. Cell Communication and Signaling 18:1.
Crossref
Xiaohua Li, Shikun He & Binyun Ma. (2020) Autophagy and autophagy-related proteins in cancer. Molecular Cancer 19:1.
Crossref
Lu Jin, Feng Yuan, Guangcheng Dai, Qiu Yao, Han Xiang, Lixia Wang, Boxin Xue, Yuxi Shan & Xiaolong Liu. (2020) Blockage of O-linked GlcNAcylation induces AMPK-dependent autophagy in bladder cancer cells. Cellular & Molecular Biology Letters 25:1.
Crossref
K. G. Lyamzaev, D. A. Knorre & B. V. Chernyak. (2020) Mitoptosis, Twenty Years After. Biochemistry (Moscow) 85:12-13, pages 1484-1498.
Crossref
Yasir Mohamud, Junyan Shi, Hui Tang, Pinhao Xiang, Yuan Chao Xue, Huitao Liu, Chen Seng Ng & Honglin Luo. (2020) Coxsackievirus infection induces a non-canonical autophagy independent of the ULK and PI3K complexes. Scientific Reports 10:1.
Crossref
Rui Peng, Yan Chen, Liangnian Wei, Gang Li, Dongju Feng, Siru Liu, Runqiu Jiang, Shaojiang Zheng & Yun Chen. (2020) Resistance to FGFR1-targeted therapy leads to autophagy via TAK1/AMPK activation in gastric cancer. Gastric Cancer 23:6, pages 988-1002.
Crossref
Peng Zhao & Alan R. Saltiel. (2020) Interaction of Adipocyte Metabolic and Immune Functions Through TBK1. Frontiers in Immunology 11.
Crossref
Noor Gammoh. (2020) The multifaceted functions of ATG16L1 in autophagy and related processes. Journal of Cell Science 133:20.
Crossref
Mukesh Kumar & Elena Papaleo. (2020) A pan-cancer assessment of alterations of the kinase domain of ULK1, an upstream regulator of autophagy. Scientific Reports 10:1.
Crossref
Chen Li, Liqun Wang, Jiaxin Liu, Yepin Yu, Youhua Huang, Xiaohong Huang, Jingguang Wei & Qiwei Qin. (2020) Singapore Grouper Iridovirus (SGIV) Inhibited Autophagy for Efficient Viral Replication. Frontiers in Microbiology 11.
Crossref
Maria Condello, Giovanna Mancini & Stefania Meschini. (2020) The Exploitation of Liposomes in the Inhibition of Autophagy to Defeat Drug Resistance. Frontiers in Pharmacology 11.
Crossref
Nirmala Tilija Pun, Won-Jun Jang & Chul-Ho Jeong. (2020) Role of autophagy in regulation of cancer cell death/apoptosis during anti-cancer therapy: focus on autophagy flux blockade. Archives of Pharmacal Research 43:5, pages 475-488.
Crossref
Satoru Torii, Hirofumi Yamaguchi, Akira Nakanishi, Satoko Arakawa, Shinya Honda, Kenta Moriwaki, Hiroyasu Nakano & Shigeomi Shimizu. (2020) Identification of a phosphorylation site on Ulk1 required for genotoxic stress-induced alternative autophagy. Nature Communications 11:1.
Crossref
Kyoung Sang Cho, Jang Ho Lee, Jeiwon Cho, Guang-Ho Cha & Gyun Jee Song. (2020) Autophagy Modulators and Neuroinflammation. Current Medicinal Chemistry 27:6, pages 955-982.
Crossref
Chen Li, Jiaxin Liu, Xin Zhang, Yepin Yu, Xiaohong Huang, Jingguang Wei & Qiwei Qin. (2020) Red grouper nervous necrosis virus (RGNNV) induces autophagy to promote viral replication. Fish & Shellfish Immunology 98, pages 908-916.
Crossref
Lauren K. Tyra, Nilay Nandi, Charles Tracy & Helmut Krämer. (2020) Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation. Developmental Cell 52:5, pages 605-616.e7.
Crossref
Bingnan He, Xia Wang, Chunlei Yang, Jianbo Zhu, Yuanxiang Jin & Zhengwei Fu. (2020) The regulation of autophagy in the pesticide-induced toxicity: Angel or demon?. Chemosphere 242, pages 125138.
Crossref
Anna Tabecka-Lonczynska, Jennifer Mytych, Przemyslaw Solek & Marek Koziorowski. (2019) Autophagy as a consequence of seasonal functions of testis and epididymis in adult male European bison (Bison bonasus, Linnaeus 1758). Cell and Tissue Research 379:3, pages 613-624.
Crossref
Li Liu, Lu Yan, Ning Liao, Wan-Qin Wu & Jun-Ling Shi. (2020) A Review of ULK1-Mediated Autophagy in Drug Resistance of Cancer. Cancers 12:2, pages 352.
Crossref
Ying Wang, Juan Cai, Chengyuan Tang & Zheng Dong. (2020) Mitophagy in Acute Kidney Injury and Kidney Repair. Cells 9:2, pages 338.
Crossref
Pablo E. Morales, Carla Arias-Durán, Yáreni Ávalos-Guajardo, Geraldine Aedo, Hugo E. Verdejo, Valentina Parra & Sergio Lavandero. (2020) Emerging role of mitophagy in cardiovascular physiology and pathology. Molecular Aspects of Medicine 71, pages 100822.
Crossref
Jun-Ling Wang & Chao-Jin Xu. (2020) Astrocytes autophagy in aging and neurodegenerative disorders. Biomedicine & Pharmacotherapy 122, pages 109691.
Crossref
Feifei Yu, Peiying Hao, Chenglong Ye, Yalin Feng, Kun Pang & Xiaoping Yu. (2020) NlATG1 Gene Participates in Regulating Autophagy and Fission of Mitochondria in the Brown Planthopper, Nilaparvata lugens. Frontiers in Physiology 10.
Crossref
Susmita Khamrui, Peter M. U. Ung, Cody Secor, Avner Schlessinger & Michael B. Lazarus. (2019) High-Resolution Structure and Inhibition of the Schizophrenia-Linked Pseudokinase ULK4. Journal of the American Chemical Society 142:1, pages 33-37.
Crossref
Charles B. Trelford & Gianni M. Di Guglielmo. (2020) Assessing methods to quantitatively validate TGFβ-dependent autophagy. Biology Open.
Crossref
Mahmoud Ahmed & Deok Ryong Kim. 2020. Prognostic and Therapeutic Applications of RKIP in Cancer. Prognostic and Therapeutic Applications of RKIP in Cancer 277 293 .
Yong-Syu Lee, Jaimee C. Eckers & Randall J. Kimple. 2020. Improving the Therapeutic Ratio in Head and Neck Cancer. Improving the Therapeutic Ratio in Head and Neck Cancer 281 300 .
Hiroaki Fujiwara, Keisuke Tateishi, Kento Misumi, Akimasa Hayashi, Kaori Igarashi, Hiroyuki Kato, Takuma Nakatsuka, Nobumi Suzuki, Keisuke Yamamoto, Yotaro Kudo, Yoku Hayakawa, Hayato Nakagawa, Yasuo Tanaka, Hideaki Ijichi, Hirofumi Kogure, Yosuke Nakai, Hiroyuki Isayama, Kiyoshi Hasegawa, Masashi Fukayama, Tomoyoshi Soga & Kazuhiko Koike. (2019) Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation. Scientific Reports 9:1.
Crossref
Ruey-Hwa Chen, Yu-Hsuan Chen & Tzu-Yu Huang. (2019) Ubiquitin-mediated regulation of autophagy. Journal of Biomedical Science 26:1.
Crossref
Wei Liu, Jing Zhuang, Yuanyuan Jiang, Jing Sun, Richard A. Prinz, Jun Sun, Xinan Jiao & Xiulong Xu. (2019) Toll‐like receptor signalling cross‐activates the autophagic pathway to restrict Salmonella Typhimurium growth in macrophages . Cellular Microbiology 21:12.
Crossref
Quynh-Giao Tran, Kichul Cho, Urim Kim, Jin-Ho Yun, Dae-hyun Cho, Jina Heo, Su-Bin Park, Ji Won Kim, Yong Jae Lee, Rishiram Ramanan & Hee-Sik Kim. (2019) Enhancement of β-carotene production by regulating the autophagy-carotenoid biosynthesis seesaw in Chlamydomonas reinhardtii. Bioresource Technology 292, pages 121937.
Crossref
Xin Sun, Peiyi Yan, Chang Zou, Yin‐Kwan Wong, Yuhan Shu, Yew Mun Lee, Chongjing Zhang, Nai‐Di Yang, Jigang Wang & Jianbin Zhang. (2019) Targeting autophagy enhances the anticancer effect of artemisinin and its derivatives. Medicinal Research Reviews 39:6, pages 2172-2193.
Crossref
Myeong Joo Kim, Gwang Yong Hwang, Min Ji Cho, Byung Hoon Chi, Serk In Park, In Ho Chang & Young Mi Whang. (2019) Depletion of NBR1 in urothelial carcinoma cells enhances rapamycin‐induced apoptosis through impaired autophagy and mitochondrial dysfunction. Journal of Cellular Biochemistry 120:11, pages 19186-19201.
Crossref
Sára Sándor & Enikő Kubinyi. (2019) Genetic Pathways of Aging and Their Relevance in the Dog as a Natural Model of Human Aging. Frontiers in Genetics 10.
Crossref
Lei Fan, Xiao-xia Qiu, Zhi-yuan Zhu, Jian-lu Lv, Jian Lu, Fei Mao, Jin Zhu, Jia-ying Wang, Xiao-wei Guan, Jing Chen, Jin Ren, Ji-ming Ye, Yong-hua Zhao, Jian Li & Xu Shen. (2019) Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice. Acta Pharmacologica Sinica 40:10, pages 1279-1291.
Crossref
Xiaoxian Shi, Senfeng Xiang, Ji Cao, Hong Zhu, Bo Yang, Qiaojun He & Meidan Ying. (2019) Kelch-like proteins: Physiological functions and relationships with diseases. Pharmacological Research 148, pages 104404.
Crossref
Giovana Ravizzoni Onzi, Juliano Luiz Faccioni, Luiza Cherobini Pereira, Marcos Paulo Thomé, Ana Paula Santin Bertoni, Julieti Huch Buss, Tiago Fazolo, Eduardo Filippi-Chiela, Márcia Rosângela Wink & Guido Lenz. (2019) Adipose-derived stromal cell secretome disrupts autophagy in glioblastoma. Journal of Molecular Medicine 97:10, pages 1491-1506.
Crossref
Akpedje S. Dossou & Alakananda Basu. (2019) The Emerging Roles of mTORC1 in Macromanaging Autophagy. Cancers 11:10, pages 1422.
Crossref
Di Sun, Xingjian Wen, Mingshu Wang, Sai Mao, Anchun Cheng, Xiaoyao Yang, Renyong Jia, Shun Chen, Qiao Yang, Ying Wu, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Yin Wang, Zhiwen Xu, Zhengli Chen, Ling Zhu, Qihui Luo, Yunya Liu, Yanling Yu, Ling Zhang & Xiaoyue Chen. (2019) Apoptosis and Autophagy in Picornavirus Infection. Frontiers in Microbiology 10.
Crossref
Young Yeon Kim, Jee‐Hyun Um, Jeong‐Hyun Yoon, Hyunjin Kim, Da‐Ye Lee, Yoon Jung Lee, Hye Jin Jee, Young Mi Kim, Jae Sung Jang, Yoon‐Gu Jang, Jongkyeong Chung, Hwan Tae Park, Toren Finkel, Hyongjong Koh & Jeanho Yun. (2019) Assessment of mitophagy in mt‐Keima Drosophila revealed an essential role of the PINK1‐Parkin pathway in mitophagy induction in vivo . The FASEB Journal 33:9, pages 9742-9751.
Crossref
Zongxu Yue, Zhimeng Lv, Yina Shao, Weiwei Zhang, Xuelin Zhao, Ming Guo & Chenghua Li. (2019) Cloning and characterization of the target protein subunit lst8 of rapamycin in Apostichopus japonicus. Fish & Shellfish Immunology 92, pages 460-468.
Crossref
Maria Zachari, Sigurdur R. Gudmundsson, Ziyue Li, Maria Manifava, Fiorella Cugliandolo, Ronak Shah, Matthew Smith, James Stronge, Eleftherios Karanasios, Caterina Piunti, Chieko Kishi-Itakura, Helena Vihinen, Eija Jokitalo, Jun-Lin Guan, Folma Buss, Andrew M. Smith, Simon A. Walker, Eeva-Liisa Eskelinen & Nicholas T. Ktistakis. (2019) Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform. Developmental Cell 50:5, pages 627-643.e5.
Crossref
Cristian Gerónimo-Olvera & Lourdes Massieu. (2019) Autophagy as a Homeostatic Mechanism in Response to Stress Conditions in the Central Nervous System. Molecular Neurobiology 56:9, pages 6594-6608.
Crossref
Jingcao Shen, Dan Yang, Xingfan Zhou, Yuqian Wang, Shichuan Tang, Hong Yin, Jinglei Wang, Rui Chen & Jiaxiang Chen. (2019) Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. International Journal of Molecular Sciences 20:16, pages 4042.
Crossref
Hui Lu, Juanjuan Xiao, Changshu Ke, Xiaofang Ni, Ruijuan Xiu, Qin Tian, Huaxiong Pan, Ling Zou, Fei Wang, Tengfei Ma, Xinying Ji, Ping Yuan, Lin Liu, Jianmin Zhang, Wei Jia, Qiuhong Duan & Feng Zhu. (2019) TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ. Cell Death & Disease 10:8.
Crossref
Olga Martinez-Arroyo, Aleksandra Gruevska, Victor M. Victor, Rosa A. González-Polo, Sokhna M.S. Yakhine-Diop, Jose M. Fuentes, Juan V. Esplugues, Ana Blas-Garcia & Nadezda Apostolova. (2019) Mitophagy in human astrocytes treated with the antiretroviral drug Efavirenz: Lack of evidence or evidence of the lack. Antiviral Research 168, pages 36-50.
Crossref
Zhen Tian, Meifang Wang, Naijuan Yao, Shujuan Yang, Jinfeng Liu, Yuan Yang, Tianyan Chen, Yingren Zhao & Yingli He. (2019) Expression of autophagy-modulating genes in peripheral blood mononuclear cells from familial clustering patients with chronic hepatitis B virus infection. Archives of Virology 164:8, pages 2005-2013.
Crossref
Siebren Faber & Ronald Roepman. (2019) Balancing the Photoreceptor Proteome: Proteostasis Network Therapeutics for Inherited Retinal Disease. Genes 10:8, pages 557.
Crossref
Elzbieta Kania & Jan B. Parys. (2019) The emerging interrelation between ROCO and related kinases, intracellular Ca2+ signaling, and autophagy. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1866:7, pages 1054-1067.
Crossref
Maria Laura A. Perez Vidakovics, Agustín E. Ure, Paula N. Arrías, Víctor Romanowski & Ricardo M. Gómez. (2019) Junín virus induces autophagy in human A549 cells. PLOS ONE 14:6, pages e0218730.
Crossref
Juan He, Jian Ding, Qiuhua Lai, Xinke Wang, Aimin Li & Side Liu. (2019) Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes. Frontiers in Physiology 10.
Crossref
Ianina C. Ferder, Leslie Fung, Yasuyo Ohguchi, Xiaoyu Zhang, Kara G. Lassen, Diane Capen, Dennis Brown, Ramnik J. Xavier & Ning Wang. (2019) Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice. PLOS Genetics 15:5, pages e1008084.
Crossref
Qiang Zeng, Wingsum Siu, Limin Li, Yu Jin, Shaoyu Liang, Meiqun Cao, Min Ma & Zhengzhi Wu. (2019) Autophagy in Alzheimer's disease and promising modulatory effects of herbal medicine. Experimental Gerontology 119, pages 100-110.
Crossref
Yan Feng, Helen H. Kang, Pui-Mun Wong, Minghui Gao, Ping Wang & Xuejun Jiang. (2018) Unc-51-like kinase (ULK) complex-independent autophagy induced by hypoxia. Protein & Cell 10:5, pages 376-381.
Crossref
Hong Ri Jin, Charles H Du, Chong-Zhi Wang, Chun-Su Yuan & Wei Du. (2019) Ginseng metabolite Protopanaxadiol induces Sestrin2 expression and AMPK activation through GCN2 and PERK. Cell Death & Disease 10:4.
Crossref
Yun Li, Ping Yang, Lei Zhao, Yao Chen, Xiaoyu Zhang, Shu Zeng, Li Wei, Zac Varghese, John F. Moorhead, Yaxi Chen & Xiong Z. Ruan. (2019) CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway. Journal of Lipid Research 60:4, pages 844-855.
Crossref
Amanda Tomie Ouchida, Valéria Tudella Uyemura, André Lima Queiroz, Verônica Soares Brauer, Marinaldo Pacífico Cavalcanti-Neto, Lucas Oliveira Sousa, Sérgio Akira Uyemura, Carlos Curti & Andréia Machado Leopoldino. (2019) SET protein accumulation prevents cell death in head and neck squamous cell carcinoma through regulation of redox state and autophagy. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1866:4, pages 623-637.
Crossref
Eun-Kyeong Jo, Prashanta Silwal & Jae-Min Yuk. (2019) AMPK-Targeted Effector Networks in Mycobacterial Infection. Frontiers in Microbiology 10.
Crossref
Apirat Chaikuad, Sebastian E. Koschade, Alexandra Stolz, Katarina Zivkovic, Christian Pohl, Shabnam Shaid, Huiyu RenLester J. LambertNicholas D.P. CosfordChristian H. Brandts & Stefan Knapp. (2019) Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2). Biochemical Journal 476:5, pages 875-887.
Crossref
Barbara Colella, Fiorella Faienza & Sabrina Di Bartolomeo. (2019) EMT Regulation by Autophagy: A New Perspective in Glioblastoma Biology. Cancers 11:3, pages 312.
Crossref
Ted G. Graber, Christopher S. Fry, Camille R. Brightwell, Tatiana Moro, Rosario Maroto, Nisha Bhattarai, Craig Porter, Maki Wakamiya & Blake B. Rasmussen. (2019) Skeletal muscle–specific knockout of DEP domain containing 5 protein increases mTORC1 signaling, muscle cell hypertrophy, and mitochondrial respiration. Journal of Biological Chemistry 294:11, pages 4091-4102.
Crossref
Ruifang Wang, Yinxing Zhu, Jiachang Zhao, Chenwei Ren, Peng Li, Huanchun Chen, Meilin Jin & Hongbo Zhou. (2019) Autophagy Promotes Replication of Influenza A Virus In Vitro . Journal of Virology 93:4.
Crossref
Maria Condello, Evelin Pellegrini, Michele Caraglia & Stefania Meschini. (2019) Targeting Autophagy to Overcome Human Diseases. International Journal of Molecular Sciences 20:3, pages 725.
Crossref
Anding Liu, Jiankun Yang, Qi Hu, Olaf Dirsch, Uta Dahmen, Cuntai Zhang, David A. Gewirtz, Haoshu Fang & Jian Sun. (2018) Young plasma attenuates age‐dependent liver ischemia reperfusion injury. The FASEB Journal 33:2, pages 3063-3073.
Crossref
Scott M. O’Grady. (2019) Oxidative stress, autophagy and airway ion transport. American Journal of Physiology-Cell Physiology 316:1, pages C16-C32.
Crossref
Adriana Marcelo, Filipa Brito, Sara Carmo-Silva, Carlos A Matos, João Alves-Cruzeiro, Ana Vasconcelos-Ferreira, Rebekah Koppenol, Liliana Mendonça, Luís Pereira de Almeida & Clévio Nóbrega. (2019) Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado–Joseph disease models. Human Molecular Genetics 28:1, pages 51-63.
Crossref
Stefan W. RyterDivya BhatiaMary E. Choi. (2019) Autophagy: A Lysosome-Dependent Process with Implications in Cellular Redox Homeostasis and Human Disease. Antioxidants & Redox Signaling 30:1, pages 138-159.
Crossref
Barbara Colella, Fiorella Faienza, Marianna Carinci, Giuseppina D'Alessandro, Myriam Catalano, Antonio Santoro, Francesco Cecconi, Cristina Limatola & Sabrina Di Bartolomeo. (2019) Autophagy induction impairs Wnt/β-catenin signalling through β-catenin relocalisation in glioblastoma cells. Cellular Signalling 53, pages 357-364.
Crossref
Gaylia Jean Harry, Gabrielle M. Childers & Christopher A. McPherson. 2019. Role of Inflammation in Environmental Neurotoxicity. Role of Inflammation in Environmental Neurotoxicity 1 34 .
Emmanuel K. CudjoeJr.Jr., S. Lauren Kyte, Tareq Saleh, Joseph W. Landry & David A. Gewirtz. 2019. Targeting Cell Survival Pathways to Enhance Response to Chemotherapy. Targeting Cell Survival Pathways to Enhance Response to Chemotherapy 259 273 .
Daolin Tang & Rui Kang. 2019. Ferroptosis in Health and Disease. Ferroptosis in Health and Disease 43 59 .
Youliang Rao, Quanyuan Wan, Hang Su, Xun Xiao, Zhiwei Liao, Jianfei Ji, Chunrong Yang, Li Lin & Jianguo Su. (2018) ROS-induced HSP70 promotes cytoplasmic translocation of high-mobility group box 1b and stimulates antiviral autophagy in grass carp kidney cells. Journal of Biological Chemistry 293:45, pages 17387-17401.
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