Autophagy, Volume 9, Issue 2 (2013)

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Autophagy, Volume 9, Issue 2 (2013)

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Editor's Corner

Editorial
Why just eat in, when you can also eat out?
Daniel J Klionsky
Page: 119
Published online: 16 Nov 2012
AbstractforWhy just eat in, when you can also eat out? | Full Text | References | PDF (513.9 KB)
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Autophagy Community

Autophagy researchers
Pages: 120-123
Published online: 13 Dec 2012
First Page PreviewforAutophagy researchers | Full Text | PDF (841.9 KB)
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Review

Review Article
The ULK1 complex
Sensing nutrient signals for autophagy activation
Pui-Mun Wong, Cindy Puente, Ian G. Ganley & Xuejun Jiang
Pages: 124-137
Published online: 07 Jan 2013
AbstractforThe ULK1 complex | Full Text | References | PDF (1.4 MB)
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Basic Research Paper

Article
Autophagy genes function in apoptotic cell corpse clearance during C. elegans embryonic development
Shuyi Huang, Kailiang Jia, Ying Wang, Zheng Zhou & Beth Levine
Pages: 138-149
Published online: 29 Oct 2012
AbstractforAutophagy genes function in apoptotic cell corpse clearance during C. elegans embryonic development | Full Text | References | PDF (7.9 MB) | Supplemental
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Article
A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy
Yanjun Li, Yuanbo Zhao, Jia Hu, Juan Xiao, Liujing Qu, Zhenda Wang, Dalong Ma & Yingyu Chen
Pages: 150-163
Published online: 26 Nov 2012
AbstractforA novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy | Full Text | References | PDF (8.5 MB) | Supplemental
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Article
An autophagy-independent role for LC3 in equine arteritis virus replication
Iryna Monastyrska, Mustafa Ulasli, Peter J.M. Rottier, Jun-Lin Guan, Fulvio Reggiori & Cornelis A.M. de Haan
Pages: 164-174
Published online: 26 Nov 2012
AbstractforAn autophagy-independent role for LC3 in equine arteritis virus replication | Full Text | References | PDF (4.4 MB) | Supplemental
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Article
Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy
He Huang, Rongyan Kang, Ji Wang, Guangxiang Luo, Wei Yang & Zhendong Zhao
Pages: 175-195
Published online: 20 Nov 2012
AbstractforHepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy | Full Text | References | PDF (4.5 MB) | Supplemental
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Article
Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells
Chong Zhao, Shutao Yin, Yinhui Dong, Xiao Guo, Lihong Fan, Min Ye & Hongbo Hu
Pages: 196-207
Published online: 26 Nov 2012
AbstractforAutophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells | Full Text | References | PDF (3.4 MB)
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Article
Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells
Yan Cheng, Xingcong Ren, Yi Zhang, Yu Shan, Kathryn J. Huber-Keener, Li Zhang, Scot R. Kimball, Harold A. Harvey, Leonard S. Jefferson & Jin-Ming Yang
Pages: 208-219
Published online: 26 Nov 2012
AbstractforIntegrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells | Full Text | References | PDF (2 MB) | Supplemental
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Translational Research Paper

Article
Autophagy is involved in endogenous and NVP-AUY922-induced KIT degradation in gastrointestinal stromal tumors
Yuan-Shuo Hsueh, Chueh-Chuan Yen, Neng-Yao Shih, Nai-Jung Chiang, Chien-Feng Li & Li-Tzong Chen
Pages: 220-233
Published online: 29 Nov 2012
AbstractforAutophagy is involved in endogenous and NVP-AUY922-induced KIT degradation in gastrointestinal stromal tumors | Full Text | References | PDF (4.2 MB)
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Autophagic Punctum

Article Commentary
Autophagic dysfunction in a lysosomal storage disorder due to impaired proteolysis
Matthew J. Elrick & Andrew P. Lieberman
Pages: 234-235
Published online: 19 Oct 2012
AbstractforAutophagic dysfunction in a lysosomal storage disorder due to impaired proteolysis | Full Text | PDF (587.9 KB)
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Article Commentary
Cell type-dependent requirement of autophagy in HSV-1 antiviral defense
Brian Yordy & Akiko Iwasaki
Pages: 236-238
Published online: 24 Oct 2012
AbstractforCell type-dependent requirement of autophagy in HSV-1 antiviral defense | Full Text | PDF (830.7 KB)
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Article Commentary
Autophagy activation ameliorates neuronal pathogenesis of FTLD-U mice
A new light for treatment of TARDBP/TDP-43 proteinopathies
I-Fang Wang, Kuen-Jer Tsai & Che-Kun James Shen
Pages: 239-240
Published online: 29 Oct 2012
AbstractforAutophagy activation ameliorates neuronal pathogenesis of FTLD-U mice | Full Text | PDF (633.5 KB)
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Article Commentary
Cathepsin-mediated regulation of autophagy in saposin C deficiency
Massimo Tatti, Marialetizia Motta, Sabrina Di Bartolomeo, Valentina Cianfanelli & Rosa Salvioli
Pages: 241-243
Published online: 29 Oct 2012
AbstractforCathepsin-mediated regulation of autophagy in saposin C deficiency | Full Text | PDF (786.5 KB)
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Article Commentary
Mitochondrial HSP90s and tumor cell metabolism
Dario C. Altieri
Pages: 244-245
Published online: 29 Oct 2012
AbstractforMitochondrial HSP90s and tumor cell metabolism | Full Text | PDF (582.5 KB)
  • 845 Views
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Article Commentary
Activation of autophagy in cells with abnormal karyotype
Silvia Stingele, Gabriele Stoehr & Zuzana Storchova
Pages: 246-248
Published online: 29 Oct 2012
AbstractforActivation of autophagy in cells with abnormal karyotype | Full Text | PDF (816.3 KB)
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Article Commentary
Atg1 kinase regulates early and late steps during autophagy
Monika Kijanska & Matthias Peter
Pages: 249-251
Published online: 29 Oct 2012
AbstractforAtg1 kinase regulates early and late steps during autophagy | Full Text | PDF (925.4 KB)
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Article Commentary
Microautophagy in the visceral endoderm is essential for mouse early development
Yoh Wada, Ge-Hong Sun-Wada & Nobuyuki Kawamura
Pages: 252-254
Published online: 29 Oct 2012
AbstractforMicroautophagy in the visceral endoderm is essential for mouse early development | Full Text | PDF (837.4 KB)
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Article Commentary
Multitargeted therapies for multiple myeloma
Pedram Kharaziha, Sophia Ceder, Claire Sanchez & Theocharis Panaretakis
Pages: 255-257
Published online: 26 Nov 2012
AbstractforMultitargeted therapies for multiple myeloma | Full Text | PDF (866.1 KB)
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Article Commentary
Ceramide stress in survival versus lethal autophagy paradox
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
Wenhui Jiang & Besim Ogretmen
Pages: 258-259
Published online: 26 Nov 2012
AbstractforCeramide stress in survival versus lethal autophagy paradox | Full Text | PDF (717.3 KB)
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Article Commentary
Hypoxia, MTOR and autophagy
Converging on senescence or quiescence
Mikhail V. Blagosklonny
Pages: 260-262
Published online: 28 Nov 2012
AbstractforHypoxia, MTOR and autophagy | Full Text | PDF (260 KB)
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Article Commentary
Programmed nuclear destruction in yeast
Self-eating by vacuolar lysis
Michael D. Eastwood, Sally W.T. Cheung & Marc D. Meneghini
Pages: 263-265
Published online: 27 Nov 2012
AbstractforProgrammed nuclear destruction in yeast | Full Text | PDF (734.1 KB)
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