Biologics: Targets and Therapy, Volume 4, Issue (2010)

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Biologics: Targets and Therapy, Volume 4, Issue (2010)

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Original Research

Article
Safety of etanercept in elderly subjects with rheumatoid arthritis
Alfredomaria Lurati, Mariagrazia Marrazza, Katia Angela & Magda Scarpellini
Pages: 1-4
Published online: 07 Dec 2022
AbstractforSafety of etanercept in elderly subjects with rheumatoid arthritis | Full Text | References | PDF (137 KB)
  • 74 Views
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Open Access

Review

Review Article
Recombinant follitropin alfa/lutropin alfa in fertility treatment
Ahmed Gibreel & Siladitya Bhattacharya
Pages: 5-17
Published online: 07 Dec 2022
AbstractforRecombinant follitropin alfa/lutropin alfa in fertility treatment | Full Text | References | PDF (283.5 KB)
  • 399 Views
  • 5 CrossRef citations
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Open Access
Review Article
Update on the treatment of gastrointestinal stromal tumors (GISTs): role of imatinib
Richard Quek & Suzanne George
Pages: 19-31
Published online: 03 Feb 2010
AbstractforUpdate on the treatment of gastrointestinal stromal tumors (GISTs): role of imatinib | Full Text | References | PDF (256 KB)
  • 65 Views
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Open Access

Original Research

Article
A combined phase I and II open label study on the effects of a seaweed extract nutrient complex on osteoarthritis
Stephen P Myers, Joan O’Connor, J Helen Fitton, Lyndon Brooks, Margaret Rolfe, Paul Connellan, Hans Wohlmuth, Phil A Cheras & Carol Morris
Pages: 33-44
Published online: 12 Feb 2010
AbstractforA combined phase I and II open label study on the effects of a seaweed extract nutrient complex on osteoarthritis | Full Text | References | PDF (302.3 KB)
  • 282 Views
  • 27 CrossRef citations
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Open Access

Review

Review Article
Overview of the pathogenesis and treatment of chronic inflammatory demyelinating polyneuropathy with intravenous immunoglobulins
Mohamed Mahdi-Rogers & Yusuf A Rajabally
Pages: 45-49
Published online: 09 Mar 2010
AbstractforOverview of the pathogenesis and treatment of chronic inflammatory demyelinating polyneuropathy with intravenous immunoglobulins | Full Text | References | PDF (132.8 KB)
  • 97 Views
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Open Access
Review Article
Use of human protein C concentrates in the treatment of patients with severe congenital protein C deficiency
Sabine Kroiss & Manuela Albisetti
Pages: 51-60
Published online: 07 Dec 2022
AbstractforUse of human protein C concentrates in the treatment of patients with severe congenital protein C deficiency | Full Text | References | PDF (181.1 KB)
  • 141 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Safety and immunogenicity of Salmonella typhimurium expressing C-terminal truncated human IL-2 in a murine model
Brent Sorenson, Kaysie Banton, Lance Augustin, Sean Barnett, Karen McCulloch, Joshua Dorn, Natalie Frykman, Arnold Leonard & Daniel Saltzman
Pages: 61-73
Published online: 16 Mar 2010
AbstractforSafety and immunogenicity of Salmonella typhimurium expressing C-terminal truncated human IL-2 in a murine model | Full Text | References | PDF (378.6 KB)
  • 81 Views
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Open Access
Article
Hepatitis B virus and Homo sapiens proteome-wide analysis: A profusion of viral peptide overlaps in neuron-specific human proteins
Rosalia Ricco & Darja Kanduc
Pages: 75-81
Published online: 01 Apr 2010
AbstractforHepatitis B virus and Homo sapiens proteome-wide analysis: A profusion of viral peptide overlaps in neuron-specific human proteins | Full Text | References | PDF (160.2 KB)
  • 66 Views
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Open Access

Review

Review Article
Management of patients with advanced non-small cell lung cancer: role of gefitinib
Vamsidhar Velcheti, Daniel Morgensztern & Ramaswamy Govindan
Pages: 83-90
Published online: 19 Apr 2010
AbstractforManagement of patients with advanced non-small cell lung cancer: role of gefitinib | Full Text | References | PDF (173.4 KB)
  • 51 Views
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Open Access
Review Article
Everolimus: the first approved product for patients with advanced renal cell cancer after sunitinib and/or sorafenib
Chris Coppin
Pages: 91-101
Published online: 30 Apr 2010
AbstractforEverolimus: the first approved product for patients with advanced renal cell cancer after sunitinib and/or sorafenib | Full Text | References | PDF (640.7 KB)
  • 78 Views
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Open Access
Review Article
Palliative treatment of malignant ascites: profile of catumaxomab
Lila Ammouri & Eric E Prommer
Pages: 103-110
Published online: 14 May 2010
AbstractforPalliative treatment of malignant ascites: profile of catumaxomab | Full Text | References | PDF (178.6 KB)
  • 195 Views
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Open Access
Review Article
Use of clofarabine for acute childhood leukemia
A Pession, R Masetti, K Kleinschmidt & A Martoni
Pages: 111-118
Published online: 07 Dec 2022
AbstractforUse of clofarabine for acute childhood leukemia | Full Text | References | PDF (158.2 KB)
  • 78 Views
  • 1 CrossRef citations
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Open Access
Review Article
Potential role of ustekinumab in the treatment of chronic plaque psoriasis
Santo Raffaele Mercuri & Luigi Naldi
Pages: 119-129
Published online: 10 May 2010
AbstractforPotential role of ustekinumab in the treatment of chronic plaque psoriasis | Full Text | References | PDF (216.3 KB)
  • 54 Views
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Open Access
Review Article
Critical appraisal of canakinumab in the treatment of adults and children with cryopyrin-associated periodic syndrome (CAPS)
Ori Toker & Philip J Hashkes
Pages: 131-138
Published online: 17 May 2010
AbstractforCritical appraisal of canakinumab in the treatment of adults and children with cryopyrin-associated periodic syndrome (CAPS) | Full Text | References | PDF (165.7 KB)
  • 89 Views
  • 6 CrossRef citations
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Open Access
Review Article
Management of chronic immune thrombocytopenic purpura: targeting insufficient megakaryopoiesis as a novel therapeutic principle
Andreas Rank, Oliver Weigert & Helmut Ostermann
Pages: 139-145
Published online: 24 May 2010
AbstractforManagement of chronic immune thrombocytopenic purpura: targeting insufficient megakaryopoiesis as a novel therapeutic principle | Full Text | References | PDF (152.3 KB)
  • 63 Views
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Open Access
Review Article
Managing idiopathic short stature: role of somatropin (rDNA origin) for injection
J Paul Frindik & Stephen F Kemp
Pages: 147-155
Published online: 09 Jun 2010
AbstractforManaging idiopathic short stature: role of somatropin (rDNA origin) for injection | Full Text | References | PDF (181.9 KB)
  • 80 Views
  • 1 CrossRef citations
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Open Access
Review Article
Decreasing glioma recurrence through adjuvant cancer stem cell inhibition
Josh Neman & Rahul Jandial
Pages: 157-162
Published online: 22 Jun 2010
AbstractforDecreasing glioma recurrence through adjuvant cancer stem cell inhibition | Full Text | References | PDF (1.5 MB)
  • 64 Views
  • 2 CrossRef citations
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Open Access

Original Research

Article
Distinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodies
Yuan Li, Janine A Burns, Carol A Cheney, Ningyan Zhang, Salvatore Vitelli, Fubao Wang, Andrew Bett, Michael Chastain, Laurent P Audoly & Zhi-Qiang Zhang
Pages: 163-171
Published online: 15 Jun 2010
AbstractforDistinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodies | Full Text | References | PDF (2.8 MB)
  • 74 Views
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Open Access

Review

Review Article
The contribution of cetuximab in the treatment of recurrent and/or metastatic head and neck cancer
Mohamedtaki A Tejani, Roger B Cohen & Ranee Mehra
Pages: 173-185
Published online: 28 Jun 2010
AbstractforThe contribution of cetuximab in the treatment of recurrent and/or metastatic head and neck cancer | Full Text | References | PDF (226.4 KB)
  • 116 Views
  • 8 CrossRef citations
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Open Access
Review Article
Rationale for targeted therapies and potential role of pazopanib in advanced renal cell carcinoma
Peter E Clark
Pages: 187-197
Published online: 28 Jun 2010
AbstractforRationale for targeted therapies and potential role of pazopanib in advanced renal cell carcinoma | Full Text | References | PDF (212.7 KB)
  • 83 Views
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Open Access
Review Article
Detection and characterization of liver lesions using gadoxetic acid as a tissue-specific contrast agent
Peter Reimer & Rolf Vosshenrich
Pages: 199-212
Published online: 04 Aug 2010
AbstractforDetection and characterization of liver lesions using gadoxetic acid as a tissue-specific contrast agent | Full Text | References | PDF (4.4 MB)
  • 85 Views
  • 1 CrossRef citations
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Open Access
Review Article
Prevention of rotavirus gastroenteritis in infants and children: rotavirus vaccine safety, efficacy, and potential impact of vaccines
Aruna Chandran, Sean Fitzwater, Anjie Zhen & Mathuram Santosham
Pages: 213-229
Published online: 30 Jul 2010
AbstractforPrevention of rotavirus gastroenteritis in infants and children: rotavirus vaccine safety, efficacy, and potential impact of vaccines | Full Text | References | PDF (3 MB)
  • 253 Views
  • 10 CrossRef citations
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Open Access
Review Article
New era in treatment for phenylketonuria: Pharmacologic therapy with sapropterin dihydrochloride
Cary O Harding
Pages: 231-236
Published online: 06 Aug 2010
AbstractforNew era in treatment for phenylketonuria: Pharmacologic therapy with sapropterin dihydrochloride | Full Text | References | PDF (176.3 KB)
  • 150 Views
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Open Access
Review Article
Current status of vandetanib (ZD6474) in the treatment of non-small cell lung cancer
Jaclyn Flanigan, Hari Deshpande & Scott Gettinger
Pages: 237-243
Published online: 26 Aug 2010
AbstractforCurrent status of vandetanib (ZD6474) in the treatment of non-small cell lung cancer | Full Text | References | PDF (160.2 KB)
  • 81 Views
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Open Access

Original Research

Article
Describing the hexapeptide identity platform between the influenza A H5N1 and Homo sapiens proteomes
Darja Kanduc
Pages: 245-261
Published online: 09 Sep 2010
AbstractforDescribing the hexapeptide identity platform between the influenza A H5N1 and Homo sapiens proteomes | Full Text | References | PDF (289.5 KB)
  • 83 Views
  • 7 CrossRef citations
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Open Access

Review

Review Article
New and emerging treatment approaches to lupus
Marion Haubitz
Pages: 263-271
Published online: 06 Sep 2010
AbstractforNew and emerging treatment approaches to lupus | Full Text | References | PDF (190 KB)
  • 69 Views
  • 2 CrossRef citations
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Open Access
Review Article
Proteasome inhibition and its therapeutic potential in multiple myeloma
Ajai Chari, Amitabha Mazumder & Sundar Jagannath
Pages: 273-287
Published online: 28 Sep 2010
AbstractforProteasome inhibition and its therapeutic potential in multiple myeloma | Full Text | References | PDF (1.3 MB)
  • 64 Views
  • 5 CrossRef citations
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Open Access
Review Article
The emerging role of nimotuzumab in the treatment of non-small cell lung cancer
William Boland & Gwyn Bebb
Pages: 289-298
Published online: 09 Nov 2010
AbstractforThe emerging role of nimotuzumab in the treatment of non-small cell lung cancer | Full Text | References | PDF (172.7 KB)
  • 89 Views
  • 8 CrossRef citations
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Open Access
Review Article
Gaucher disease: clinical profile and therapeutic developments
Timothy M Cox
Pages: 299-313
Published online: 06 Dec 2010
AbstractforGaucher disease: clinical profile and therapeutic developments | Full Text | References | PDF (1.1 MB)
  • 452 Views
  • 27 CrossRef citations
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Open Access
Review Article
Principal long-term adverse effects of imatinib in patients with chronic myeloid leukemia in chronic phase
Tariq I Mughal & Andrew Schrieber
Pages: 315-323
Published online: 02 Dec 2010
AbstractforPrincipal long-term adverse effects of imatinib in patients with chronic myeloid leukemia in chronic phase | Full Text | References | PDF (235.8 KB)
  • 423 Views
  • 32 CrossRef citations
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Open Access
Review Article
Complexing proteins in botulinum toxin type A drugs: a help or a hindrance?
Jürgen Frevert & Dirk Dressler
Pages: 325-332
Published online: 09 Dec 2010
AbstractforComplexing proteins in botulinum toxin type A drugs: a help or a hindrance? | Full Text | References | PDF (581.2 KB)
  • 463 Views
  • 30 CrossRef citations
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