Pharmaceutical Development and Technology, Volume 18, Issue 5 (2013)

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Pharmaceutical Development and Technology, Volume 18, Issue 5 (2013)

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Research Article

Article
Influence of Carbopol 71G-NF on the release of dextromethorphan hydrobromide from extended-release matrix tablets
Mohamed H. Fayed, Gamal M. Mahrous, Mohamed A. Ibrahim & Adel Sakr
Pages: 971-981
Published online: 03 Jun 2011
AbstractforInfluence of Carbopol 71G-NF on the release of dextromethorphan hydrobromide from extended-release matrix tablets | Full Text | References | PDF (950.9 KB)
  • 219 Views
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Article
Characterization of ethyl cellulose polymer
Tazin Mahnaj, Salah U. Ahmed & Fotios M. Plakogiannis
Pages: 982-989
Published online: 24 Aug 2011
AbstractforCharacterization of ethyl cellulose polymer | Full Text | References | PDF (1.4 MB)
  • 653 Views
  • 17 CrossRef citations
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Article
Self-assembled carbohydrate hydrogels for prolonged pain management
R. Kamel & H. A. Abbas
Pages: 990-1004
Published online: 27 Sep 2011
AbstractforSelf-assembled carbohydrate hydrogels for prolonged pain management | Full Text | References | PDF (1.1 MB)
  • 188 Views
  • 23 CrossRef citations
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Article
Rapid pain relief using transdermal film forming polymeric solution of ketorolac
H. O. Ammar, M. Ghorab, A. A. Mahmoud, T. S. Makram & A. M. Ghoneim
Pages: 1005-1016
Published online: 23 Dec 2011
AbstractforRapid pain relief using transdermal film forming polymeric solution of ketorolac | Full Text | References | PDF (922.9 KB)
  • 302 Views
  • 28 CrossRef citations
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Article
Preparation and evaluation of polymer based microcarriers for all-trans-retinoic acid
Demet Daşkın & Ufuk Gündüz
Pages: 1017-1025
Published online: 20 Mar 2012
AbstractforPreparation and evaluation of polymer based microcarriers for all-trans-retinoic acid | Full Text | References | PDF (771.1 KB)
  • 185 Views
  • 3 CrossRef citations
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Article
Temperature-sensitive hydrogels by graft polymerization of chitosan and N-isopropylacrylamide for drug release
Umile Gianfranco Spizzirri, Francesca Iemma, Giuseppe Cirillo, Ilaria Altimari, Francesco Puoci & Nevio Picci
Pages: 1026-1034
Published online: 27 Dec 2011
AbstractforTemperature-sensitive hydrogels by graft polymerization of chitosan and N-isopropylacrylamide for drug release | Full Text | References | PDF (804.2 KB)
  • 165 Views
  • 9 CrossRef citations
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Article
Modulated dissolution rate from the inclusion complex of antichagasic benznidazole and cyclodextrin using hydrophilic polymer
Lívia C. L. Sá-Barreto, Pricila C. Gustmann, Felipe S. Garcia, Flávia P. Maximiano, Kátia M. Novack & Marcílio S. S. Cunha-Filho
Pages: 1035-1041
Published online: 27 Dec 2011
AbstractforModulated dissolution rate from the inclusion complex of antichagasic benznidazole and cyclodextrin using hydrophilic polymer | Full Text | References | PDF (722.6 KB)
  • 124 Views
  • 11 CrossRef citations
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Article
Preparation and characterization of mosapride citrate inclusion complexes with natural and synthetic cyclodextrins
Adel A. Ali & Ossama M. Sayed
Pages: 1042-1050
Published online: 30 Dec 2011
AbstractforPreparation and characterization of mosapride citrate inclusion complexes with natural and synthetic cyclodextrins | Full Text | References | PDF (1.1 MB)
  • 96 Views
  • 4 CrossRef citations
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Article
Polyamidomine dendrimers: an excellent drug carrier for improving the solubility and bioavailability of puerarin
Lin Gu, Zheng hong Wu, Xiaole Qi, Huan He, Xiaoli Ma, Xiaohua Chou, Xiaoguang Wen, Miao Zhang & Fang Jiao
Pages: 1051-1057
Published online: 05 Feb 2012
AbstractforPolyamidomine dendrimers: an excellent drug carrier for improving the solubility and bioavailability of puerarin | Full Text | References | PDF (767 KB)
  • 212 Views
  • 37 CrossRef citations
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Article
Flavonoids preservation and release by methacrylic acid-grafted (N-vinyl-pyrrolidone)
Ortensia Ilaria Parisi, Francesco Puoci, Francesca Iemma, Manuela Curcio, Giuseppe Cirillo, Umile Gianfranco Spizzirri & Nevio Picci
Pages: 1058-1065
Published online: 23 Apr 2012
AbstractforFlavonoids preservation and release by methacrylic acid-grafted (N-vinyl-pyrrolidone) | Full Text | References | PDF (791.5 KB)
  • 80 Views
  • 10 CrossRef citations
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Article
A novel pH-dependant and double crosslinked polymethacrylate-based polysphere matrix for enteric delivery of isoniazid
Shivaan Cooppan, Yahya E. Choonara, Lisa C. du Toit, Valence M. K. Ndesendo, Pradeep Kumar & Viness Pillay
Pages: 1066-1077
Published online: 17 May 2012
AbstractforA novel pH-dependant and double crosslinked polymethacrylate-based polysphere matrix for enteric delivery of isoniazid | Full Text | References | PDF (1.4 MB)
  • 71 Views
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Article
Hydrophilic versus hydrophobic porogens for engineering of poly(lactide-co-glycolide) microparticles containing risedronate sodium
Maha Nasr, Gehanne A. S. Awad, Samar Mansour, Abdelhamid Al Shamy & Nahed D. Mortada
Pages: 1078-1088
Published online: 02 Jun 2012
AbstractforHydrophilic versus hydrophobic porogens for engineering of poly(lactide-co-glycolide) microparticles containing risedronate sodium | Full Text | References | PDF (1 MB)
  • 157 Views
  • 13 CrossRef citations
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Article
Influence of ethanol on swelling and release behaviors of Carbopol®-based tablets
Safwan Abdel Rahim, Mutasim Al-Ghazawi & Nizar Al-Zoubi
Pages: 1089-1100
Published online: 09 Jul 2012
AbstractforInfluence of ethanol on swelling and release behaviors of Carbopol®-based tablets | Full Text | References | PDF (1.1 MB)
  • 187 Views
  • 10 CrossRef citations
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Article
Development of orally disintegrating tablets of Perphenazine/hydroxypropyl-β-cyclodextrin inclusion complex
Ling Wang, Fan Zeng & Li Zong
Pages: 1101-1110
Published online: 03 Jul 2012
AbstractforDevelopment of orally disintegrating tablets of Perphenazine/hydroxypropyl-β-cyclodextrin inclusion complex | Full Text | References | PDF (844.2 KB)
  • 227 Views
  • 11 CrossRef citations
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Article
Deproteinized natural rubber film forming polymeric solutions for nicotine transdermal delivery
Wiwat Pichayakorn, Jirapornchai Suksaeree, Prapaporn Boonme, Thanaporn Amnuaikit, Wirach Taweepreda & Garnpimol C. Ritthidej
Pages: 1111-1121
Published online: 13 Aug 2012
AbstractforDeproteinized natural rubber film forming polymeric solutions for nicotine transdermal delivery | Full Text | References | PDF (881.3 KB)
  • 202 Views
  • 32 CrossRef citations
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Article
Effect of different polymers and their combinations on the release of metoclopramide HCl from sustained-release hydrophilic matrix tablets
Ayhan Savaşer, Çetin Taş, Ziya Bayrak, Cansel Köse Özkan & Yalçın Özkan
Pages: 1122-1130
Published online: 13 Aug 2012
AbstractforEffect of different polymers and their combinations on the release of metoclopramide HCl from sustained-release hydrophilic matrix tablets | Full Text | References | PDF (896.5 KB)
  • 249 Views
  • 9 CrossRef citations
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Article
Design, development and optimization of oral colon targeted drug delivery system of azathioprine using biodegradable polymers
Bipul Nath & L. K. Nath
Pages: 1131-1139
Published online: 21 Nov 2012
AbstractforDesign, development and optimization of oral colon targeted drug delivery system of azathioprine using biodegradable polymers | Full Text | References | PDF (783.9 KB)
  • 218 Views
  • 8 CrossRef citations
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Article
Fabrication and properties of capsicum extract-loaded PVA and CA nanofiber patches
Praneet Opanasopit, Warisada Sila-on, Theerasak Rojanarata & Tanasait Ngawhirunpat
Pages: 1140-1147
Published online: 04 Oct 2012
AbstractforFabrication and properties of capsicum extract-loaded PVA and CA nanofiber patches | Full Text | References | PDF (768.1 KB)
  • 250 Views
  • 23 CrossRef citations
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Article
Development and in vivo evaluation of novel monolithic controlled release compositions of galantamine hydrobromide as against reservoir technology
Umesh Nandkumar Khatavkar, Shamkant Laxman Shimpi, K Jayaram Kumar & Kishor Dattatraya Deo
Pages: 1148-1158
Published online: 20 Jul 2011
AbstractforDevelopment and in vivo evaluation of novel monolithic controlled release compositions of galantamine hydrobromide as against reservoir technology | Full Text | References | PDF (924 KB)
  • 143 Views
  • 3 CrossRef citations
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Article
In vitro characterization and growth inhibition effect of nanostructured lipid carriers for controlled delivery of methotrexate
Ghada Abdelbary & Mohamed Haider
Pages: 1159-1168
Published online: 29 Sep 2011
AbstractforIn vitro characterization and growth inhibition effect of nanostructured lipid carriers for controlled delivery of methotrexate | Full Text | References | PDF (913.7 KB)
  • 207 Views
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Article
Effects of formulation parameters on encapsulation efficiency and release behavior of thienorphine loaded PLGA microspheres
Yang Yang, Yongliang Gao & Xingguo Mei
Pages: 1169-1174
Published online: 04 Oct 2011
AbstractforEffects of formulation parameters on encapsulation efficiency and release behavior of thienorphine loaded PLGA microspheres | Full Text | References | PDF (857.3 KB)
  • 307 Views
  • 8 CrossRef citations
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Article
Development and evaluation of chitosan microspheres for tetanus, diphtheria and divalent vaccines: a comparative study of subcutaneous and intranasal administration in mice
Fahima M. Hashem, Sahar A. Fahmy, Aly M. El-Sayed & Majid M. Al-Sawahli
Pages: 1175-1185
Published online: 10 Oct 2011
AbstractforDevelopment and evaluation of chitosan microspheres for tetanus, diphtheria and divalent vaccines: a comparative study of subcutaneous and intranasal administration in mice | Full Text | References | PDF (750.9 KB)
  • 157 Views
  • 7 CrossRef citations
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Article
Micromechanical and physical stability analysis of an irradiated poly (lactic-co-glycolic acid) donut-shaped minitablet device for intraocular implantation
Yahya E. Choonara, Viness Pillay, Michael P. Danckwerts, Trevor R. Carmichael, Lisa C. du Toit & Riaz A. Khan
Pages: 1186-1203
Published online: 16 Feb 2012
AbstractforMicromechanical and physical stability analysis of an irradiated poly (lactic-co-glycolic acid) donut-shaped minitablet device for intraocular implantation | Full Text | References | PDF (1.3 MB)
  • 122 Views
  • 1 CrossRef citations
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Article
Formulation and In vitro assessment of sustained release terbutaline sulfate tablet made from binary hydrophilic polymer mixtures
Faisal Al-Akayleh, Mayyas Al Remawi, Iyad Rashid & Adnan Badwan
Pages: 1204-1212
Published online: 06 Oct 2011
AbstractforFormulation and In vitro assessment of sustained release terbutaline sulfate tablet made from binary hydrophilic polymer mixtures | Full Text | References | PDF (1.1 MB)
  • 128 Views
  • 12 CrossRef citations
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Article
Formulation parameters and release mechanism of theophylline loaded ethyl cellulose microspheres: effect of different dual surfactant ratios
Mohan Thakare, Bridgette Israel, Solomon T. Garner, Hisham Ahmed, Pamela Garner, Deborah Elder, James C. Price & Anthony C. Capomacchia
Pages: 1213-1219
Published online: 12 Oct 2011
AbstractforFormulation parameters and release mechanism of theophylline loaded ethyl cellulose microspheres: effect of different dual surfactant ratios | Full Text | References | PDF (711.5 KB)
  • 183 Views
  • 9 CrossRef citations
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Article
β-methasone-containing biodegradable poly(lactide-co-glycolide) acid microspheres for intraarticular injection: effect of formulation parameters on characteristics and in vitro release
Xia Song, San-Kong Song, Pei Zhao, Li-Ming Wei & Hai-Sheng Jiao
Pages: 1220-1229
Published online: 01 Feb 2012
Abstractforβ-methasone-containing biodegradable poly(lactide-co-glycolide) acid microspheres for intraarticular injection: effect of formulation parameters on characteristics and in vitro release | Full Text | References | PDF (875.3 KB)
  • 150 Views
  • 6 CrossRef citations
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Article
Development of gastroretentive drug delivery system for cefuroxime axetil: In vitro and in vivo evaluation in human volunteers
Ramesh Bomma & Kishan Veerabrahma
Pages: 1230-1237
Published online: 21 Feb 2012
AbstractforDevelopment of gastroretentive drug delivery system for cefuroxime axetil: In vitro and in vivo evaluation in human volunteers | Full Text | References | PDF (854.1 KB)
  • 207 Views
  • 14 CrossRef citations
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Article
Optimization of propranolol HCl release kinetics from press coated sustained release tablets
Adel Ahmed Ali & Ahmed Mahmoud Ali
Pages: 1238-1246
Published online: 14 May 2012
AbstractforOptimization of propranolol HCl release kinetics from press coated sustained release tablets | Full Text | References | PDF (1.1 MB)
  • 134 Views
  • 10 CrossRef citations
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Article
Optimization of primaquine diphosphate tablet formulation for controlled drug release using the mixture experimental design
Marcelo Dutra Duque, Rogério Nepomuceno Kreidel, Maria Elena Santos Taqueda, André Rolim Baby, Telma Mary Kaneko, Maria Valéria Robles Velasco & Vladi Olga Consiglieri
Pages: 1247-1254
Published online: 07 Jun 2012
AbstractforOptimization of primaquine diphosphate tablet formulation for controlled drug release using the mixture experimental design | Full Text | References | PDF (706.5 KB)
  • 119 Views
  • 2 CrossRef citations
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Short Report

Poly(galactaramidoamine) is an efficient cationic polymeric non-viral vector with low cytotoxicity for transfecting human embryonic kidney (HEK293) and murine macrophage (RAW264.7) cells
Amaraporn Wongrakpanich, Vijaya B. Joshi & Aliasger K. Salem
Pages: 1255-1258
Published online: 12 Jan 2012
AbstractforPoly(galactaramidoamine) is an efficient cationic polymeric non-viral vector with low cytotoxicity for transfecting human embryonic kidney (HEK293) and murine macrophage (RAW264.7) cells | Full Text | References | PDF (586.2 KB)
  • 148 Views
  • 1 CrossRef citations
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Technical Note

The influence of the degree of esterification on the release characteristics of in situ gelling pectin formulations for oral sustained delivery of paracetamol
Shozo Miyazaki, Hanae Murofushi, Tetsuya Shimoyama, Kunihiko Itoh, Michiya Kobayashi & David Attwood
Pages: 1259-1264
Published online: 05 Feb 2012
AbstractforThe influence of the degree of esterification on the release characteristics of in situ gelling pectin formulations for oral sustained delivery of paracetamol | Full Text | References | PDF (702.4 KB)
  • 131 Views
  • 3 CrossRef citations
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