Autophagy, Volume 11, Issue 10 (2015)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Autophagy, Volume 11, Issue 10 (2015)

See all volumes and issues
Vol 20, 2024 Vol 19, 2023 Vol 18, 2022 Vol 17, 2021 Vol 16, 2020 Vol 15, 2019 Vol 14, 2018 Vol 13, 2017 Vol 12, 2016 Volume 11, 2015 Vol 10, 2014 Vol 9, 2013 Vol 8, 2012 Vol 7, 2011 Vol 6, 2010 Vol 5, 2009 Vol 4, 2008 Vol 3, 2007 Vol 2, 2006 Vol 1, 2005
Download citations Download PDFs Download issue

EDITOR'S CORNER

Editorial
The amino acid transporter SLC38A9 regulates MTORC1 and autophagy
Meiyan Jin & Daniel J Klionsky
Pages: 1709-1710
Published online: 27 Oct 2015
AbstractforThe amino acid transporter SLC38A9 regulates MTORC1 and autophagy | Full Text | References | PDF (43.5 KB)
  • 2185 Views
  • 7 CrossRef citations
  • 0Altmetric
Free Access

REVIEW

Review
Differential regulatory functions of three classes of phosphatidylinositol and phosphoinositide 3-kinases in autophagy
Xinlei Yu, Yun Chau Long & Han-Ming Shen
Pages: 1711-1728
Published online: 27 Oct 2015
AbstractforDifferential regulatory functions of three classes of phosphatidylinositol and phosphoinositide 3-kinases in autophagy | Full Text | References | PDF (454.4 KB)
  • 5539 Views
  • 123 CrossRef citations
  • 0Altmetric
Free Access

BASIC RESEARCH PAPERS

Article
Activation of autophagy in macrophages by pro-resolving lipid mediators
Patricia Prieto, César Eduardo Rosales-Mendoza, Verónica Terrón, Víctor Toledano, Antonio Cuadrado, Eduardo López-Collazo, Gerard Bannenberg, Paloma Martín-Sanz, María Fernández-Velasco & Lisardo Boscá
Pages: 1729-1744
Published online: 27 Oct 2015
AbstractforActivation of autophagy in macrophages by pro-resolving lipid mediators | Full Text | References | PDF (1.5 MB) | Supplemental
  • 2584 Views
  • 56 CrossRef citations
  • 0Altmetric
Free Access
Article
Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation
Ling-Yan Su, Hao Li, Li Lv, Yue-Mei Feng, Guo-Dong Li, Rongcan Luo, He-Jiang Zhou, Xiao-Guang Lei, Liang Ma, Jia-Li Li, Lin Xu, Xin-Tian Hu & Yong-Gang Yao
Pages: 1745-1759
Published online: 27 Oct 2015
AbstractforMelatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation | Full Text | References | PDF (1.8 MB) | Supplemental
  • 4184 Views
  • 78 CrossRef citations
  • 0Altmetric
Free Access
Article
TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy and reduces renal dysfunction in a cyclosporine A-induced nephrotoxicity model
Raj Kumar Yadav, Geum-Hwa Lee, Hwa-Young Lee, Bo Li, Han-Eul Jung, Harun-Or Rashid, Min Kyung Choi, Binod Kumar Yadav, Woo-Ho Kim, Kyung-Woon Kim, Byung-Hyun Park, Won Kim, Yong-Chul Lee, Hyung-Ryong Kim & Han-Jung Chae
Pages: 1760-1774
Published online: 27 Oct 2015
AbstractforTMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy and reduces renal dysfunction in a cyclosporine A-induced nephrotoxicity model | Full Text | References | PDF (1.7 MB) | Supplemental
  • 2790 Views
  • 27 CrossRef citations
  • 0Altmetric
Free Access
Article
Molecular basis of ubiquitin recognition by the autophagy receptor CALCOCO2
Xingqiao Xie, Faxiang Li, Yuanyuan Wang, Yingli Wang, Zhijie Lin, Xiaofang Cheng, Jianping Liu, Changbin Chen & Lifeng Pan
Pages: 1775-1789
Published online: 27 Oct 2015
AbstractforMolecular basis of ubiquitin recognition by the autophagy receptor CALCOCO2 | Full Text | References | PDF (1.3 MB) | Supplemental
  • 2987 Views
  • 49 CrossRef citations
  • 0Altmetric
Free Access
Article
MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation
David Colecchia, Matteo Rossi, Federica Sasdelli, Sveva Sanzone, Angela Strambi & Mario Chiariello
Pages: 1790-1802
Published online: 27 Oct 2015
AbstractforMAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation | Full Text | References | PDF (1.4 MB) | Supplemental
  • 2253 Views
  • 29 CrossRef citations
  • 0Altmetric
Open Access
Article
GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A
Ting-Ting Du, Le Wang, Chun-Li Duan, Ling-Ling Lu, Jian-Liang Zhang, Ge Gao, Xiao-Bo Qiu, Xiao-Min Wang & Hui Yang
Pages: 1803-1820
Published online: 27 Oct 2015
AbstractforGBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A | Full Text | References | PDF (1.5 MB) | Supplemental
  • 3938 Views
  • 94 CrossRef citations
  • 0Altmetric
Free Access
Article
Autophagy supports color vision
Zhenqing Zhou, Frans Vinberg, Frank Schottler, Teresa A Doggett, Vladimir J Kefalov & Thomas A Ferguson
Pages: 1821-1832
Published online: 27 Oct 2015
AbstractforAutophagy supports color vision | Full Text | References | PDF (1.3 MB) | Supplemental
  • 2472 Views
  • 29 CrossRef citations
  • 0Altmetric
Free Access
Article
RAB24 facilitates clearance of autophagic compartments during basal conditions
Päivi Ylä-Anttila, Elisa Mikkonen, Kaisa E Happonen, Petter Holland, Takashi Ueno, Anne Simonsen & Eeva-Liisa Eskelinen
Pages: 1833-1848
Published online: 27 Oct 2015
AbstractforRAB24 facilitates clearance of autophagic compartments during basal conditions | Full Text | References | PDF (1.8 MB) | Supplemental
  • 2367 Views
  • 34 CrossRef citations
  • 0Altmetric
Free Access
Article
Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells
Xuejiao Zhao, Yong Fang, Yang Yang, Yu Qin, Peng Wu, Ting Wang, Huiling Lai, Li Meng, Daowen Wang, Zhihui Zheng, Xinhua Lu, Hua Zhang, Qinglei Gao, Jianfeng Zhou & Ding Ma
Pages: 1849-1863
Published online: 27 Oct 2015
AbstractforElaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells | Full Text | References | PDF (1.6 MB) | Supplemental
  • 4018 Views
  • 87 CrossRef citations
  • 0Altmetric
Free Access

BASIC RESEARCH PAPER

Article
Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation
Yair Botbol, Bindi Patel & Fernando Macian
Pages: 1864-1877
Published online: 27 Oct 2015
AbstractforCommon γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation | Full Text | References | PDF (841 KB) | Supplemental
  • 1691 Views
  • 46 CrossRef citations
  • 0Altmetric
Free Access

CLINICAL RESEARCH PAPER

Article
Combined evaluation of LC3B puncta and HMGB1 expression predicts residual risk of relapse after adjuvant chemotherapy in breast cancer
Sylvain Ladoire, Frédérique Penault-Llorca, Laura Senovilla, Cécile Dalban, David Enot, Clara Locher, Nicole Prada, Vichnou Poirier-Colame, Kariman Chaba, Laurent Arnould, François Ghiringhelli, Pierre Fumoleau, Marc Spielmann, Suzette Delaloge, Marie Laure Poillot, Patrick Arveux, Aicha Goubar, Fabrice Andre, Laurence Zitvogel & Guido Kroemer
Pages: 1878-1890
Published online: 27 Oct 2015
AbstractforCombined evaluation of LC3B puncta and HMGB1 expression predicts residual risk of relapse after adjuvant chemotherapy in breast cancer | Full Text | References | PDF (985.8 KB) | Supplemental
  • 2632 Views
  • 76 CrossRef citations
  • 0Altmetric
Free Access

TRANSLATIONAL RESEARCH PAPER

Article
Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux
Sandy Giuliano, Yann Cormerais, Maeva Dufies, Renaud Grépin, Pascal Colosetti, Amine Belaid, Julien Parola, Anthony Martin, Sandra Lacas-Gervais, Nathalie M Mazure, Rachid Benhida, Patrick Auberger, Baharia Mograbi & Gilles Pagès
Pages: 1891-1904
Published online: 27 Oct 2015
AbstractforResistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux | Full Text | References | PDF (1.1 MB) | Supplemental
  • 3453 Views
  • 75 CrossRef citations
  • 0Altmetric
Free Access

TOOLBOX

Quantitative analysis of autophagic flux by confocal pH-imaging of autophagic intermediates
Giuseppe Maulucci, Michela Chiarpotto, Massimiliano Papi, Daniela Samengo, Giovambattista Pani & Marco De Spirito
Pages: 1905-1916
Published online: 27 Oct 2015
AbstractforQuantitative analysis of autophagic flux by confocal pH-imaging of autophagic intermediates | Full Text | References | PDF (1 MB) | Supplemental
  • 4350 Views
  • 61 CrossRef citations
  • 0Altmetric
Open Access

RESOURCE

Article
ncRDeathDB: A comprehensive bioinformatics resource for deciphering network organization of the ncRNA-mediated cell death system
Deng Wu, Yan Huang, Juanjuan Kang, Kongning Li, Xiaoman Bi, Ting Zhang, Nana Jin, Yongfei Hu, Puwen Tan, Lu Zhang, Ying Yi, Wenjun Shen, Jian Huang, Xiaobo Li, Xia Li, Jianzhen Xu & Dong Wang
Pages: 1917-1926
Published online: 27 Oct 2015
AbstractforncRDeathDB: A comprehensive bioinformatics resource for deciphering network organization of the ncRNA-mediated cell death system | Full Text | References | PDF (523.1 KB) | Supplemental
  • 1541 Views
  • 56 CrossRef citations
  • 0Altmetric
Free Access

AUTOPHAGIC PUNCTA

Article
Eat or be eaten: The autophagic plight of inactive 26S proteasomes
Richard S Marshall & Richard D Vierstra
Pages: 1927-1928
Published online: 27 Oct 2015
AbstractforEat or be eaten: The autophagic plight of inactive 26S proteasomes | Full Text | PDF (53.8 KB)
  • 1902 Views
  • 30 CrossRef citations
  • 0Altmetric
Free Access
Article
The TRIB3-SQSTM1 interaction mediates metabolic stress-promoted tumorigenesis and progression via suppressing autophagic and proteasomal degradation
Fang Hua, Ke Li, Jiao-Jiao Yu & Zhuo-Wei Hu
Pages: 1929-1931
Published online: 27 Oct 2015
AbstractforThe TRIB3-SQSTM1 interaction mediates metabolic stress-promoted tumorigenesis and progression via suppressing autophagic and proteasomal degradation | Full Text | PDF (220.6 KB)
  • 2417 Views
  • 16 CrossRef citations
  • 0Altmetric
Free Access
Article
BCL2L13 is a mammalian homolog of the yeast mitophagy receptor Atg32
Kinya Otsu, Tomokazu Murakawa & Osamu Yamaguchi
Pages: 1932-1933
Published online: 27 Oct 2015
AbstractforBCL2L13 is a mammalian homolog of the yeast mitophagy receptor Atg32 | Full Text | PDF (124.3 KB)
  • 3183 Views
  • 61 CrossRef citations
  • 0Altmetric
Free Access
Article
Progressive endolysosomal deficits impair autophagic clearance beginning at early asymptomatic stages in fALS mice
Yuxiang Xie, Bing Zhou, Mei-Yao Lin & Zu-Hang Sheng
Pages: 1934-1936
Published online: 27 Oct 2015
AbstractforProgressive endolysosomal deficits impair autophagic clearance beginning at early asymptomatic stages in fALS mice | Full Text | PDF (224.5 KB)
  • 1589 Views
  • 23 CrossRef citations
  • 0Altmetric
Free Access
Article
Tumor suppressor functions of BNIP3 and mitophagy
Aparajita H Chourasia & Kay F Macleod
Pages: 1937-1938
Published online: 27 Oct 2015
AbstractforTumor suppressor functions of BNIP3 and mitophagy | Full Text | PDF (149.2 KB)
  • 4969 Views
  • 93 CrossRef citations
  • 0Altmetric
Free Access
Article
Frameshift mutation of UVRAG: Switching a tumor suppressor to an oncogene in colorectal cancer
Shanshan He & Chengyu Liang
Pages: 1939-1940
Published online: 27 Oct 2015
AbstractforFrameshift mutation of UVRAG: Switching a tumor suppressor to an oncogene in colorectal cancer | Full Text | PDF (50.8 KB)
  • 1366 Views
  • 14 CrossRef citations
  • 0Altmetric
Free Access

VIEWS AND COMMENTARIES

Article Commentary
Autophagic death probed by photodynamic therapy
David Kessel
Pages: 1941-1943
Published online: 27 Oct 2015
AbstractforAutophagic death probed by photodynamic therapy | Full Text | References | PDF (56.3 KB)
  • 1040 Views
  • 23 CrossRef citations
  • 0Altmetric
Free Access
Article Commentary
ITPRs/inositol 1,4,5-trisphosphate receptors in autophagy: From enemy to ally
Jean-Paul Decuypere, Jan B Parys & Geert Bultynck
Pages: 1944-1948
Published online: 27 Oct 2015
AbstractforITPRs/inositol 1,4,5-trisphosphate receptors in autophagy: From enemy to ally | Full Text | References | PDF (277.6 KB)
  • 1914 Views
  • 19 CrossRef citations
  • 0Altmetric
Open Access

MEETING REPORT

Report
Precision autophagy: Will the next wave of selective autophagy markers and specific autophagy inhibitors feed clinical pipelines?
Chandra B Lebovitz, Lindsay DeVorkin, Damien Bosc, Katharina Rothe, Jagbir Singh, Marcel Bally, Xiaoyan Jiang, Robert N Young, Julian J Lum & Sharon M Gorski
Pages: 1949-1952
Published online: 27 Oct 2015
AbstractforPrecision autophagy: Will the next wave of selective autophagy markers and specific autophagy inhibitors feed clinical pipelines? | Full Text | References | PDF (78.3 KB)
  • 2551 Views
  • 16 CrossRef citations
  • 0Altmetric
Open Access

Explore articles

Explore the most recently published articles

Key considerations for investigating and interpreting autophagy in skeletal muscle
Fasih A. Rahman et al.
Review Article | Published online: 15 Jul 2024
Proteostasis in health and disease: a conversation with Professor Rick Morimoto
Richard I. Morimoto et al.
Review Article | Published online: 15 Jul 2024
Open Access
Lassa virus Z protein hijacks the autophagy machinery for efficient transportation by interrupting CCT2-mediated cytoskeleton network formation
Yueming Yuan et al.
Article | Published online: 15 Jul 2024
Individual Atg8 paralogs exhibit unique properties in streptococcus pneumoniae-induced hierarchical autophagy
Sayaka Shizukuishi et al.
Article Commentary | Published online: 11 Jul 2024
View all latest articles