Autophagy, Volume 8, Issue 1 (2012)

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Autophagy, Volume 8, Issue 1 (2012)

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Editor's Corner

Editorial
The end of autophagic cell death?
Shensi Shen, Oliver Kepp & Guido Kroemer
Pages: 1-3
Published online: 01 Jan 2012
AbstractforThe end of autophagic cell death? | PDF (322.9 KB)
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Autophagic Flux

Editorial
Highlights from this issue
Andriy Nemchenko
Pages: 4-5
Published online: 01 Jan 2012
CitationforHighlights from this issue | PDF (639.4 KB)
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Review

Review Article
Beclin1: A role in membrane dynamics and beyond
Ellen Wirawan, Saskia Lippens, Tom Vanden Berghe, Alessandra Romagnoli, Gian Maria Fimia, Mauro Piacentini & Peter Vandenabeele
Pages: 6-17
Published online: 01 Jan 2012
AbstractforBeclin1: A role in membrane dynamics and beyond | PDF (2.2 MB)
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Basic Research Paper

Article
DRAM-1 encodes multiple isoforms that regulate autophagy
Li Yen Mah, Jim O’Prey, Alice D. Baudot, Attje Hoekstra & Kevin M. Ryan
Pages: 18-28
Published online: 01 Jan 2012
AbstractforDRAM-1 encodes multiple isoforms that regulate autophagy | Full Text | References | PDF (5.2 MB) | Supplemental
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Article
Vid30 is required for the association of Vid vesicles and actin patches in the vacuole import and degradation pathway
Abbas A. Alibhoy, Bennett J. Giardina, Danielle D. Dunton & Hui-Ling Chiang
Pages: 29-46
Published online: 01 Jan 2012
AbstractforVid30 is required for the association of Vid vesicles and actin patches in the vacuole import and degradation pathway | Full Text | References | PDF (4.4 MB)
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Article
Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan
Sören Mai, Britta Muster, Jürgen Bereiter-Hahn & Marina Jendrach
Pages: 47-62
Published online: 01 Jan 2012
AbstractforAutophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan | Full Text | References | PDF (7.3 MB) | Supplemental
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Article
Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction
Shihui Xing, Yusheng Zhang, Jingjing Li, Jian Zhang, Yiliang Li, Chao Dang, Chuo Li, Yuhua Fan, Jian Yu, Zhong Pei & Jinsheng Zeng
Pages: 63-76
Published online: 01 Jan 2012
AbstractforBeclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction | PDF (6.9 MB)
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Article
Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia
Pei Wang, Yun-Feng Guan, Hui Du, Qi-Wei Zhai, Ding-Feng Su & Chao-Yu Miao
Pages: 77-87
Published online: 01 Jan 2012
AbstractforInduction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia | PDF (6.7 MB)
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Article
The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation
Isei Tanida, Manabu Yamasaki, Masaaki Komatsu & Takashi Ueno
Pages: 88-97
Published online: 01 Jan 2012
AbstractforThe FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation | PDF (3.1 MB)
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Translational Research Paper

Article
Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy
Jia-Hong Lu, Jie-Qiong Tan, Siva Sundara Kumar Durairajan, Liang-Feng Liu, Zhuo-Hua Zhang, Long Ma, Han-Ming Shen, H.Y. Edwin Chan & Min Li
Pages: 98-108
Published online: 01 Jan 2012
AbstractforIsorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy | PDF (4 MB)
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Article
Autophagy-mediated HMGB1 release antagonizes apoptosis of gastric cancer cells induced by vincristine via transcriptional regulation of Mcl-1
ZhenZhen Zhan, Qun Li, Ping Wu, Yan Ye, Hsin-Yi Tseng, Linjie Zhang & Xu Dong Zhang
Pages: 109-121
Published online: 01 Jan 2012
AbstractforAutophagy-mediated HMGB1 release antagonizes apoptosis of gastric cancer cells induced by vincristine via transcriptional regulation of Mcl-1 | PDF (2.3 MB) | Supplemental
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Autophagic Punctum

Article Commentary
Autophagy and ammonia
Heesun Cheong, Tullia Lindsten & Craig B. Thompson
Pages: 122-123
Published online: 01 Jan 2012
AbstractforAutophagy and ammonia | Full Text | PDF (277.6 KB)
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Article Commentary
Circadian regulation of autophagy rhythm through transcription factor C/EBPβ
Di Ma & Jiandie D. Lin
Pages: 124-125
Published online: 01 Jan 2012
AbstractforCircadian regulation of autophagy rhythm through transcription factor C/EBPβ | Full Text | PDF (317 KB)
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Article Commentary
Autophagy: A new player in hepatic stellate cell activation
Lien F.R. Thoen, Eduardo L. Guimarães & Leo A. van Grunsven
Pages: 126-128
Published online: 01 Jan 2012
AbstractforAutophagy: A new player in hepatic stellate cell activation | PDF (556.8 KB)
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Article Commentary
Pro-tumorigenic function of autophagy in mammary oncogenesis
Huijun Wei & Jun-Lin Guan
Pages: 129-131
Published online: 01 Jan 2012
AbstractforPro-tumorigenic function of autophagy in mammary oncogenesis | Full Text | PDF (221.9 KB)
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Article Commentary
Listeria and autophagy escape
Involvement of InlK, an internalin-like protein
Laurent Dortet, Serge Mostowy & Pascale Cossart
Pages: 132-134
Published online: 01 Jan 2012
AbstractforListeria and autophagy escape | Full Text | PDF (421.5 KB)
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Article Commentary
Autop38-phagy and apop38-tosis in genotoxic stress: A strange duo
Miguel Ángel de la Cruz-Morcillo & Ricardo Sánchez-Prieto
Pages: 135-137
Published online: 01 Jan 2012
AbstractforAutop38-phagy and apop38-tosis in genotoxic stress: A strange duo | PDF (456.9 KB)
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Article Commentary
Glycogen synthase kinase-3β controls autophagy during myocardial ischemia and reperfusion
Peiyong Zhai & Junichi Sadoshima
Pages: 138-139
Published online: 01 Jan 2012
AbstractforGlycogen synthase kinase-3β controls autophagy during myocardial ischemia and reperfusion | Full Text | PDF (162.3 KB)
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Article Commentary
Critical role of autophagy in ischemia/reperfusion injury to aged livers
Jin-Hee Wang, Kevin E. Behrns, Christiaan Leeuwenburgh & Jae-Sung Kim
Pages: 140-141
Published online: 01 Jan 2012
AbstractforCritical role of autophagy in ischemia/reperfusion injury to aged livers | Full Text | PDF (194.6 KB)
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Article Commentary
TOR-autophagy signaling in adult zebrafish models of cardiomyopathy
Yonghe Ding, Xiaojing Sun & Xiaolei Xu
Pages: 142-143
Published online: 01 Jan 2012
AbstractforTOR-autophagy signaling in adult zebrafish models of cardiomyopathy | Full Text | PDF (156.4 KB)
  • 963 Views
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Article Commentary
Autophagy links lipid metabolism to longevity in C. elegans
Louis R. Lapierre, Alicia Meléndez & Malene Hansen
Pages: 144-146
Published online: 01 Jan 2012
AbstractforAutophagy links lipid metabolism to longevity in C. elegans | Full Text | PDF (514.5 KB)
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Views and Commentaries

Review Article
Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome
Implications for normal aging and age-dependent neurodegenerative disorders
John J. Graziotto, Kan Cao, Francis S. Collins & Dimitri Krainc
Pages: 147-151
Published online: 01 Jan 2012
AbstractforRapamycin activates autophagy in Hutchinson-Gilford progeria syndrome | Full Text | References | PDF (430.3 KB)
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