OncoImmunology, Volume 8, Issue 9 (2019)

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OncoImmunology, Volume 8, Issue 9 (2019)

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Original Research

Article
DNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth
Jennifer L. Miller-Ocuin, Xiaoyan Liang, Brian A. Boone, W. Reed Doerfler, Aatur D. Singhi, Daolin Tang, Rui Kang, Michael T. Lotze & Herbert J. Zeh III
Article: e1605822
Published online: 11 Jun 2019
AbstractforDNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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Open Access
Article
High-throughput assessment of the antibody profile in ovarian cancer ascitic fluids
Frank Antony, Cecilia Deantonio, Diego Cotella, Maria Felicia Soluri, Olga Tarasiuk, Francesco Raspagliesi, Fulvio Adorni, Silvano Piazza, Yari Ciani, Claudio Santoro, Paolo Macor, Delia Mezzanzanica & Daniele Sblattero
Article: e1614856
Published online: 04 Jun 2019
AbstractforHigh-throughput assessment of the antibody profile in ovarian cancer ascitic fluids | Full Text | References | PDF (4.5 MB) | EPUB | Supplemental
  • 2277 Views
  • 19 CrossRef citations
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Free Access
Article
Immune microenvironment profiling of gastrointestinal stromal tumors (GIST) shows gene expression patterns associated to immune checkpoint inhibitors response
Maria A. Pantaleo, Giuseppe Tarantino, Claudio Agostinelli, Milena Urbini, Margherita Nannini, Maristella Saponara, Chiara Castelli, Silvia Stacchiotti, Elena Fumagalli, Lidia Gatto, Donatella Santini, Antonio De Leo, Teresa Marafioti, Ayse Akarca, Elena Sabattini, Andrea Pession, Andrea Ardizzoni, Valentina Indio & Annalisa Astolfi
Article: e1617588
Published online: 04 Jun 2019
AbstractforImmune microenvironment profiling of gastrointestinal stromal tumors (GIST) shows gene expression patterns associated to immune checkpoint inhibitors response | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 5179 Views
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Open Access
Article
T cells engrafted with a UniCAR 28/z outperform UniCAR BB/z-transduced T cells in the face of regulatory T cell-mediated immunosuppression
Alexandra Kegler, Stefanie Koristka, Ralf Bergmann, Nicole Berndt, Claudia Arndt, Anja Feldmann, Anja Hoffmann, Martin Bornhäuser, Marc Schmitz & Michael P. Bachmann
Article: e1621676
Published online: 07 Jun 2019
AbstractforT cells engrafted with a UniCAR 28/z outperform UniCAR BB/z-transduced T cells in the face of regulatory T cell-mediated immunosuppression | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
  • 2432 Views
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Open Access
Article
Development and validation of an interferon signature predicting prognosis and treatment response for glioblastoma
Chen Zhu, Cunyi Zou, Gefei Guan, Qing Guo, Zihao Yan, Tianqi Liu, Shuai Shen, Xiaoyan Xu, Chen Chen, Zhiguo Lin, Wen Cheng & Anhua Wu
Article: e1621677
Published online: 12 Jun 2019
AbstractforDevelopment and validation of an interferon signature predicting prognosis and treatment response for glioblastoma | Full Text | References | PDF (5.4 MB) | EPUB | Supplemental
  • 2950 Views
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Free Access
Article
Atezolizumab potentiates Tcell-mediated cytotoxicity and coordinates with FAK to suppress cell invasion and motility in PD-L1+ triple negative breast cancer cells
Nishant Mohan, Salman Hosain, Jun Zhao, Yi Shen, Xiao Luo, Jiangsong Jiang, Yukinori Endo & Wen Jin Wu
Article: e1624128
Published online: 06 Jun 2019
AbstractforAtezolizumab potentiates Tcell-mediated cytotoxicity and coordinates with FAK to suppress cell invasion and motility in PD-L1+ triple negative breast cancer cells | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 4894 Views
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Open Access
Article
Neutrophil Cathepsin G and Tumor Cell RAGE Facilitate Neutrophil Anti-Tumor Cytotoxicity
Ronit Vogt Sionov, Tanya Fainsod-Levi, Tamir Zelter, Lola Polyansky, Christine T. Pham & Zvi Granot
Article: e1624129
Published online: 11 Jun 2019
AbstractforNeutrophil Cathepsin G and Tumor Cell RAGE Facilitate Neutrophil Anti-Tumor Cytotoxicity | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 2158 Views
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Free Access
Article
A multivariate Th17 metagene for prognostic stratification in T cell non-inflamed triple negative breast cancer
L. Faucheux, M. Grandclaudon, M. Perrot-Dockès, P. Sirven, F. Berger, A.S. Hamy, V. Fourchotte, A. Vincent-Salomon, F. Mechta-Grigoriou, F. Reyal, A. Scholer-Dahirel, M. Guillot-Delost & V. Soumelis
Article: e1624130
Published online: 24 Jun 2019
AbstractforA multivariate Th17 metagene for prognostic stratification in T cell non-inflamed triple negative breast cancer | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
  • 2377 Views
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Open Access
Article
NPM-ALK-reactive T-cell responses in children and adolescents with NPM-ALK positive anaplastic large cell lymphoma
Vijay Kumar Singh, Sebastian Werner, Simone Schwalm, Volker Lennerz, Stephanie Ruf, Serena Stadler, Holger Hackstein, Alfred Reiter, Thomas Wölfel, Christine Damm-Welk & Wilhelm Woessmann
Article: e1625688
Published online: 26 Jun 2019
AbstractforNPM-ALK-reactive T-cell responses in children and adolescents with NPM-ALK positive anaplastic large cell lymphoma | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 1619 Views
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Open Access
Article
CCR5 status and metastatic progression in colorectal cancer
Meggy Suarez-Carmona, Pornpimol Chaorentong, Jakob Nikolas Kather, Rebecca Rothenheber, Azaz Ahmed, Anna Berthel, Anita Heinzelmann, Rodrigo Moraleda, Nektarios A. Valous, Zeynep Kosaloglu, Rosa Eurich, Jana Wolf, Silke Grauling-Halama, Michael Hundemer, Felix Lasitschka, Fee Klupp, Christoph Kahlert, Alexis Ulrich, Martin Schneider, Christine Falk, Dirk Jäger, Inka Zoernig & Niels Halama
Article: e1626193
Published online: 13 Jul 2019
AbstractforCCR5 status and metastatic progression in colorectal cancer | Full Text | References | PDF (4.6 MB) | EPUB | Supplemental
  • 4060 Views
  • 27 CrossRef citations
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Open Access
Article
High tumoral PD-L1 expression and low PD-1+ or CD8+ tumor-infiltrating lymphocytes are predictive of a poor prognosis in primary diffuse large B-cell lymphoma of the central nervous system
Sehui Kim, Soo Jeong Nam, Changhee Park, Dohee Kwon, Jeemin Yim, Seung Geun Song, Chan-Young Ock, Young A Kim, Sung Hye Park, Tae Min Kim & Yoon Kyung Jeon
Article: e1626653
Published online: 10 Jun 2019
AbstractforHigh tumoral PD-L1 expression and low PD-1+ or CD8+ tumor-infiltrating lymphocytes are predictive of a poor prognosis in primary diffuse large B-cell lymphoma of the central nervous system | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 1759 Views
  • 20 CrossRef citations
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Free Access
Article
Aberrant fucosylation enables breast cancer clusterin to interact with dendritic cell-specific ICAM-grabbing non-integrin (DC-SIGN)
Antonela Merlotti, Alvaro López Malizia, Paula Michea, Pierre-Emmanuel Bonte, Christel Goudot, María Sol Carregal, Nicolás Nuñez, Christine Sedlik, Ana Ceballos, Vassili Soumelis, Sebastián Amigorena, Jorge Geffner, Eliane Piaggio & Juan Sabatte
Article: e1629257
Published online: 24 Jun 2019
AbstractforAberrant fucosylation enables breast cancer clusterin to interact with dendritic cell-specific ICAM-grabbing non-integrin (DC-SIGN) | Full Text | References | PDF (3.8 MB) | EPUB
  • 2562 Views
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Open Access
Article
High tumor mutation burden predicts better efficacy of immunotherapy: a pooled analysis of 103078 cancer patients
Dedong Cao, Huilin Xu, Ximing Xu, Tao Guo & Wei Ge
Article: e1629258
Published online: 16 Jun 2019
AbstractforHigh tumor mutation burden predicts better efficacy of immunotherapy: a pooled analysis of 103078 cancer patients | Full Text | References | PDF (3.9 MB) | EPUB | Supplemental
  • 2991 Views
  • 77 CrossRef citations
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Free Access
Article
HPV16 RNA-LPX vaccine mediates complete regression of aggressively growing HPV-positive mouse tumors and establishes protective T cell memory
Christian Grunwitz, Nadja Salomon, Fulvia Vascotto, Abderaouf Selmi, Thomas Bukur, Mustafa Diken, Sebastian Kreiter, Özlem Türeci & Ugur Sahin
Article: e1629259
Published online: 11 Jul 2019
AbstractforHPV16 RNA-LPX vaccine mediates complete regression of aggressively growing HPV-positive mouse tumors and establishes protective T cell memory | Full Text | References | PDF (4.3 MB) | EPUB | Supplemental
  • 6613 Views
  • 45 CrossRef citations
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Open Access
Article
Targeted transcriptional profiling of the tumor microenvironment reveals lymphocyte exclusion and vascular dysfunction in metastatic osteosarcoma
Laurie Sorenson, Yanfen Fu, Tressa Hood, Sarah Warren & Troy A. McEachron
Article: e1629779
Published online: 27 Jun 2019
AbstractforTargeted transcriptional profiling of the tumor microenvironment reveals lymphocyte exclusion and vascular dysfunction in metastatic osteosarcoma | Full Text | References | PDF (4.8 MB) | EPUB | Supplemental
  • 1640 Views
  • 6 CrossRef citations
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Free Access
Article
Immunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line
Anna Kreutzman, Bhagwan Yadav, Tim H. Brummendorf, Bjorn Tore Gjertsen, Moon Hee Lee, Jeroen Janssen, Tiina Kasanen, Perttu Koskenvesa, Kourosh Lotfi, Berit Markevärn, Ulla Olsson-Strömberg, Jesper Stentoft, Leif Stenke, Stina Söderlund, Lene Udby, Johan Richter, Henrik Hjorth-Hansen & Satu Mustjoki
Article: e1638210
Published online: 13 Jul 2019
AbstractforImmunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line | Full Text | References | PDF (5.6 MB) | EPUB | Supplemental
  • 3292 Views
  • 18 CrossRef citations
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Open Access
Article
Phenotypic and functional analysis of malignant mesothelioma tumor-infiltrating lymphocytes
Astero Klampatsa, Shaun M. O’Brien, Jeffrey C. Thompson, Abhishek S. Rao, Jason E. Stadanlick, Marina C. Martinez, Maria Liousia, Edward Cantu, Keith Cengel, Edmund K. Moon, Sunil Singhal, Evgeniy B. Eruslanov & Steven M. Albelda
Article: e1638211
Published online: 13 Jul 2019
AbstractforPhenotypic and functional analysis of malignant mesothelioma tumor-infiltrating lymphocytes | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 2810 Views
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Free Access

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