Leukemia & Lymphoma, Volume 62, Issue 7 (2021)

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Leukemia & Lymphoma, Volume 62, Issue 7 (2021)

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Commentry

Article Commentary
All activated signaling pathways lead to anaplastic large cell lymphoma (ALCL)
Irina Bonzheim & Leticia Quintanilla-Martinez
Pages: 1541-1543
Published online: 21 May 2021
First Page PreviewforAll activated signaling pathways lead to anaplastic large cell lymphoma (ALCL) | Full Text | References | PDF (304.6 KB) | EPUB
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Reviews

Measurable residual disease in multiple myeloma and light chain amyloidosis: more than meets the eye
Iuliana Vaxman & Morie A. Gertz
Pages: 1544-1553
Published online: 28 Jan 2021
AbstractforMeasurable residual disease in multiple myeloma and light chain amyloidosis: more than meets the eye | Full Text | References | PDF (976.3 KB) | EPUB
  • 390 Views
  • 2 CrossRef citations
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Advanced-stage Hodgkin lymphoma: have effective therapy and modern imaging changed the significance of bulky disease?
Sarah A. Milgrom, Bouthaina S. Dabaja & N. George Mikhaeel
Pages: 1554-1562
Published online: 07 Feb 2021
AbstractforAdvanced-stage Hodgkin lymphoma: have effective therapy and modern imaging changed the significance of bulky disease? | Full Text | References | PDF (682.6 KB) | EPUB
  • 227 Views
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Original Articles

Article
MDMX/MDM4 is highly expressed and contributes to cell growth and survival in anaplastic large cell lymphoma
Vaios Sinatkas, Konstantina Stathopoulou, Ioanna Xagoraris, Jingjing Ye, Dimitra Vyrla, Vasilios Atsaves, Vasiliki Leventaki, L. Jeffrey Medeiros, George Z. Rassidakis & Elias Drakos
Pages: 1563-1573
Published online: 11 Feb 2021
AbstractforMDMX/MDM4 is highly expressed and contributes to cell growth and survival in anaplastic large cell lymphoma | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 224 Views
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Article
lncRNA SNHG14 promotes oncogenesis and immune evasion in diffuse large-B-cell lymphoma by sequestering miR-152-3p
Yuyang Tian, Lianqiao Li, Guoqiang Lin, Yan Wang, Li Wang, Qian Zhao, Youdong Hu, Hongmei Yong, Yan Wan & Yanming Zhang
Pages: 1574-1584
Published online: 08 Mar 2021
AbstractforlncRNA SNHG14 promotes oncogenesis and immune evasion in diffuse large-B-cell lymphoma by sequestering miR-152-3p | Full Text | References | PDF (2.1 MB) | EPUB
  • 182 Views
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Article
Tamoxifen enhances romidepsin-induced apoptosis in T-cell malignant cells via activation of FOXO1 signaling pathway
Chinadol Wanitpongpun, Yoshio Honma, Takahiro Okada, Ritsuro Suzuki, Urano Takeshi & Junji Suzumiya
Pages: 1585-1596
Published online: 28 Jan 2021
AbstractforTamoxifen enhances romidepsin-induced apoptosis in T-cell malignant cells via activation of FOXO1 signaling pathway | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 111 Views
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Article
Metabolomic approach to characterize the metabolic phenotypes and varied response to ouabain of diffuse large B-cell lymphoma cells
Meihong Zheng, Xuan Zhou, Qien Wang, Xin Chen, Bei Cao & Juan Li
Pages: 1597-1608
Published online: 10 Feb 2021
AbstractforMetabolomic approach to characterize the metabolic phenotypes and varied response to ouabain of diffuse large B-cell lymphoma cells | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 1687 Views
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Open Access
Article
Classic Hodgkin lymphoma in Guatemalan children of age less than six years: analysis of immune regulatory pathways and the tumor microenvironment
Oscar Silva, Vivek Charu, Mark D. Ewalt, Ryan A. Metcalf, Shuchun Zhao, E. Mauricio Castellanos, Elizabeth Orellana, Yasodha Natkunam & Sandra Luna-Fineman
Pages: 1609-1618
Published online: 24 Feb 2021
AbstractforClassic Hodgkin lymphoma in Guatemalan children of age less than six years: analysis of immune regulatory pathways and the tumor microenvironment | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
  • 196 Views
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Article
Results of a completely outpatient autologous stem cell transplant program for lymphoma patients receiving reduced-intensity conditioning
José C. Jaime-Pérez, Marcela Hernández-Coronado, Ernesto Picón-Galindo, Lorena Salazar-Cavazos, César Homero Gutiérrez-Aguirre & David Gómez-Almaguer
Pages: 1619-1628
Published online: 24 Jan 2021
AbstractforResults of a completely outpatient autologous stem cell transplant program for lymphoma patients receiving reduced-intensity conditioning | Full Text | References | PDF (1.5 MB) | EPUB
  • 231 Views
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Article
Sequential intensive chemotherapy followed by autologous or allogeneic transplantation for refractory lymphoma
Nina Orfali, Yuliya Jhanwar, Calvin Koo, Michelle Pasciolla, Maria Baldo, Edwidge Cuvilly, Richard Furman, Usama Gergis, June Greenberg, Danielle Guarneri, Jing-Mei Hsu, John P. Leonard, Tomer Mark, Sebastian Mayer, Kathleen Maignan, Peter Martin, Adomah Opong, Roger Pearse, Adrienne Phillips, Adriana Rossi, Jia Ruan, Sarah C. Rutherford, Jessy Ryan, Grace Suhu, Koen Van Besien & Tsiporah Shore
Pages: 1629-1638
Published online: 13 Feb 2021
AbstractforSequential intensive chemotherapy followed by autologous or allogeneic transplantation for refractory lymphoma | Full Text | References | PDF (918.9 KB) | EPUB | Supplemental
  • 488 Views
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Article
Female patients with follicular lymphoma have a better prognosis if primary remission lasts over 24 months
Aino Rajamäki, Kaisa Sunela, Roosa E. I. Prusila, Milla E. L. Kuusisto, Santiago Mercadal, Tuomas Selander, Hanne Kuitunen, Marjukka Pollari, Esa Jantunen, Ilja Nystrand, Juan-Manuel Sancho, Marc Sorigue & Outi Kuittinen
Pages: 1639-1647
Published online: 05 Feb 2021
AbstractforFemale patients with follicular lymphoma have a better prognosis if primary remission lasts over 24 months | Full Text | References | PDF (1.7 MB) | EPUB
  • 1735 Views
  • 3 CrossRef citations
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Open Access
Article
PD-L1 expression in peripheral T-cell lymphomas is not related to either PD-L1 gene amplification or rearrangements
Rebeca Manso, Sandra Rodríguez-Perales, Raúl Torres-Ruiz, Carlos Santonja & Socorro-María Rodríguez-Pinilla
Pages: 1648-1656
Published online: 07 Feb 2021
AbstractforPD-L1 expression in peripheral T-cell lymphomas is not related to either PD-L1 gene amplification or rearrangements | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 320 Views
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Article
Non-EBV infection-associated hemophagocytic lymphohistiocytosis: a distinct subgroup where pathogen-directed therapy is essential and favorable outcomes are expected
Yahong You, Jingshi Wang, Yini Wang, Na Wei, Lin Wu, Leilei Chen, Deli Song & Zhao Wang
Pages: 1657-1663
Published online: 13 Feb 2021
AbstractforNon-EBV infection-associated hemophagocytic lymphohistiocytosis: a distinct subgroup where pathogen-directed therapy is essential and favorable outcomes are expected | Full Text | References | PDF (563.7 KB) | EPUB
  • 135 Views
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Article
Outcomes in chronic lymphocytic leukemia patients on novel agents in the US Veterans Health Administration System
Christopher R. Frei, Hannah Le, Daniel McHugh, Kellie Ryan, Xavier Jones, Samantha Galley, Kathleen Franklin, Courtney J. Baus, Juan Tavera, Michelle Janania-Martinez, David Gregorio, Snegha Ananth, Ricardo Uribe, Prathibha Surapaneni, Manuel Espinoza-Gutarra, Michael M. Song, Chengwen Teng, Obiageri O. Obodozie-Ofoegbu & Zohra Nooruddin
Pages: 1664-1673
Published online: 11 Feb 2021
AbstractforOutcomes in chronic lymphocytic leukemia patients on novel agents in the US Veterans Health Administration System | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 507 Views
  • 4 CrossRef citations
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Article
Randomized controlled trial of individualized, low dose, fixed duration lenalidomide maintenance versus observation after frontline chemo-immunotherapy in CLL
Nishant Jindal, Deepesh P. Lad, Pankaj Malhotra, Gaurav Prakash, Alka Khadwal, Arihant Jain, Manupdesh Singh Sachdeva, Sreejesh Sreedharanunni, Shano Naseem, Neelam Varma & Subhash Varma
Pages: 1674-1681
Published online: 21 Feb 2021
AbstractforRandomized controlled trial of individualized, low dose, fixed duration lenalidomide maintenance versus observation after frontline chemo-immunotherapy in CLL | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 362 Views
  • 3 CrossRef citations
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Article
Haematological malignancy and nosocomial transmission are associated with an increased risk of death from COVID-19: results of a multi-center UK cohort
Talvinder Bhogal, Umair T. Khan, Rebecca Lee, Alexander Stockdale, Christian Hesford, Vaishnav Potti-Dhananjaya, Avith Jathanna, Shaun Rahman, Ann Tivey, Rohan Shotton, Ram Sundar, Christopher Valerio, Amir Norouzi, Philip Walker, Ruth Suckling, Anne Armstrong, Gillian Brearton, Andrew Pettitt, Nagesh Kalakonda, Daniel H. Palmer, Richard Jackson, Lance Turtle & Carlo Palmieri
Pages: 1682-1691
Published online: 28 Jan 2021
AbstractforHaematological malignancy and nosocomial transmission are associated with an increased risk of death from COVID-19: results of a multi-center UK cohort | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 3119 Views
  • 18 CrossRef citations
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Open Access
Article
Characteristics and risk factors of infections following CD28-based CD19 CAR-T cells
Talya Wittmann Dayagi, Gilad Sherman, Bella Bielorai, Etai Adam, Michal J. Besser, Avichai Shimoni, Arnon Nagler, Amos Toren, Elad Jacoby & Abraham Avigdor
Pages: 1692-1701
Published online: 10 Feb 2021
AbstractforCharacteristics and risk factors of infections following CD28-based CD19 CAR-T cells | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 506 Views
  • 12 CrossRef citations
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Article
Impact of next generation sequencing results on clinical management in patients with hematological disorders
Bhumika J. Patel, Shimoli V. Barot, Yan Xie, James R. Cook, Hetty E. Carraway & Eric D. Hsi
Pages: 1702-1710
Published online: 03 Feb 2021
AbstractforImpact of next generation sequencing results on clinical management in patients with hematological disorders | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 366 Views
  • 3 CrossRef citations
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Article
Specific HLA alleles, paired with TCR V- and J-gene segment usage, link to distinct multiple myeloma survival rates
Taha I. Huda, Moody Mihyu, Etienne C. Gozlan, Mary F. Arndt, Michael J. Diaz, Saif Zaman, Boris I. Chobrutskiy & George Blanck
Pages: 1711-1720
Published online: 24 Feb 2021
AbstractforSpecific HLA alleles, paired with TCR V- and J-gene segment usage, link to distinct multiple myeloma survival rates | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 99 Views
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Article
A phase-1 trial of linsitinib (OSI-906) in combination with bortezomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma
Sahar Khan, Richard LeBlanc, Martin Gyger, Darrell White, Johnathan Kaufman, Andrzej Jazubowiak, Engin Gul, Harminder Paul, Lisa W. Le, Anthea Lau, Zhihua Li & Suzanne Trudel
Pages: 1721-1729
Published online: 28 Jan 2021
AbstractforA phase-1 trial of linsitinib (OSI-906) in combination with bortezomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 274 Views
  • 1 CrossRef citations
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Article
Tyrosine kinase inhibitor therapy discontinuation in patients with chronic myeloid leukemia in chronic phase in the United States after clinical practice guideline updates
Ehab L. Atallah, Islam Sadek, Rodrigo Maegawa, Xiting Cao, Dominick Latremouille-Viau, Irina Pivneva, Carmine Rossi, Annie Guerin & Vamsi Kota
Pages: 1730-1739
Published online: 01 Mar 2021
AbstractforTyrosine kinase inhibitor therapy discontinuation in patients with chronic myeloid leukemia in chronic phase in the United States after clinical practice guideline updates | Full Text | References | PDF (981.6 KB) | EPUB | Supplemental
  • 479 Views
  • 2 CrossRef citations
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Article
A dose escalation study of RO6870810/TEN-10 in patients with acute myeloid leukemia and myelodysplastic syndrome
Gail J. Roboz, Pinkal Desai, Sangmin Lee, Ellen K. Ritchie, Eric S. Winer, Mark DeMario, Barbara Brennan, Eveline Nüesch, Evelyne Chesne, Laura Brennan, Katharina Lechner, Martin Kornacker & Daniel J. DeAngelo
Pages: 1740-1748
Published online: 13 Feb 2021
AbstractforA dose escalation study of RO6870810/TEN-10 in patients with acute myeloid leukemia and myelodysplastic syndrome | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 361 Views
  • 10 CrossRef citations
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Article
Searching for germline mutations in the RUNX1 gene among Polish patients with acute myeloid leukemia
Aneta Bąk, Katarzyna Skonieczka, Anna Jaśkowiec, Anna Junkiert-Czarnecka, Marta Heise, Maria Pilarska-Deltow, Stanisław Potoczek, Maria Czyżewska & Olga Haus
Pages: 1749-1755
Published online: 10 Feb 2021
AbstractforSearching for germline mutations in the RUNX1 gene among Polish patients with acute myeloid leukemia | Full Text | References | PDF (720.8 KB) | EPUB
  • 214 Views
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Letters to the Editor

Letter
Data from French named patient program of quizartinib in relapsed/refractory acute myeloid leukemia
S. Fodil, E. Raffoux, P. Y. Dumas, Y. Desbrosses, F. Larosa, S. Chantepie, M. V. Larcher, J. B. Mear, P. Peterlin, M. Hunault-Berger, M. A. Hospital, V. Morel, N. Lucas, V. Vidal, C. Salanoubat, J. Michel, C. Mediavilla, M. Ojeda-Uribe, M. Alexis, J. Frayfer, M. Carré, N. Maillard, R. Redjoul, A. Banos, M. Detrait, T. Cluzeau, S. Wickenhauser, D. Chaoui, M. Elassy, A. Pigneux, H. Dombret, C. Récher, S. Bertoli & on behalf of the French AML Intergroup ALFA/FILO
Pages: 1756-1760
Published online: 17 Feb 2021
First Page PreviewforData from French named patient program of quizartinib in relapsed/refractory acute myeloid leukemia | Full Text | References | PDF (513.4 KB) | EPUB | Supplemental
  • 174 Views
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Letter
Targeting the glucagon receptor signaling pathway as a novel strategy to counteract PI3K inhibitor induced hyperglycemia while sustaining tumor PI3K inhibition
Jie Wang, Takuya Osada, Michael A. Morse, Frank Calzone, Hai Yan, Dung Thai & H. Kim Lyerly
Pages: 1761-1764
Published online: 12 Feb 2021
First Page PreviewforTargeting the glucagon receptor signaling pathway as a novel strategy to counteract PI3K inhibitor induced hyperglycemia while sustaining tumor PI3K inhibition | Full Text | References | PDF (793.9 KB) | EPUB
  • 1617 Views
  • 1 CrossRef citations
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Open Access
Letter
Management of hemophagocytic lymphohistiocytosis (HLH) associated with chimeric antigen receptor T-cell (CAR-T) therapy using anti-cytokine therapy: an illustrative case and review of the literature
Ajay Major, Jennifer Collins, Caroline Craney, Alisa K. Heitman, Emily Bauer, Elizabeth Zerante, Wendy Stock, Michael R. Bishop & Jagoda Jasielec
Pages: 1765-1769
Published online: 09 Feb 2021
First Page PreviewforManagement of hemophagocytic lymphohistiocytosis (HLH) associated with chimeric antigen receptor T-cell (CAR-T) therapy using anti-cytokine therapy: an illustrative case and review of the literature | Full Text | References | PDF (937.9 KB) | EPUB
  • 942 Views
  • 17 CrossRef citations
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Letter
ATG2B/GSKIP in de novo acute myeloid leukemia (AML): high prevalence of germline predisposition in French West Indies
Jean Pegliasco, Barbara Schmaltz-Panneau, Jean-Edouard Martin, Samy Chraibi, Sabine Khalife-Hachem, Flore Salviat, Florence Pasquier, Christophe Willekens, Maureen Lopez, Adel Ben-ali, Odile Bera, Olivier Caron, Cristina Castilla-Llorent, Sophie Cotteret, Carole Bourdin, Veronique Saada, Nathalie Auger, Stephane de Botton, William Vainchenker, Pascal Fuseau, Philippe Helias, Raouf Benabdelali, Christophe Marzac, Jean-Come Meniane, Isabelle Plo, Christine Bellanné-Chantelot & Jean-Baptiste Micol
Pages: 1770-1773
Published online: 07 Feb 2021
First Page PreviewforATG2B/GSKIP in de novo acute myeloid leukemia (AML): high prevalence of germline predisposition in French West Indies | Full Text | References | PDF (908.9 KB) | EPUB | Supplemental
  • 225 Views
  • 3 CrossRef citations
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Letter
Predicting severe toxicities with intensive induction chemotherapy for adult acute myeloid leukemia: analysis of SWOG Cancer Research Network trials S0106 and S1203
Anna Moseley, Megan Othus, Guillermo Garcia-Manero, Frederick R. Appelbaum, Harry P. Erba & Roland B. Walter
Pages: 1774-1777
Published online: 09 Feb 2021
First Page PreviewforPredicting severe toxicities with intensive induction chemotherapy for adult acute myeloid leukemia: analysis of SWOG Cancer Research Network trials S0106 and S1203 | Full Text | References | PDF (523.9 KB) | EPUB | Supplemental
  • 197 Views
  • 0 CrossRef citations
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Letter
Cladribine, cytarabine, and GCSF with and without mitoxantrone (CLAG ± M) is highly effective for poor risk acute myeloid leukemia with adverse karyotype and prior hypomethylating therapy
Amanda Przespolewski, Monica R. Muppidi, Craig W. Freyer, Wenyan Ji, Tara L. Cronin, Swapna Thota, Elizabeth A. Griffiths, James E. Thompson, Evelena P. Ontiveros, Jeffrey Baron, Amro Elshoury & Eunice S. Wang
Pages: 1778-1781
Published online: 16 Feb 2021
First Page PreviewforCladribine, cytarabine, and GCSF with and without mitoxantrone (CLAG ± M) is highly effective for poor risk acute myeloid leukemia with adverse karyotype and prior hypomethylating therapy | Full Text | References | PDF (730.6 KB) | EPUB | Supplemental
  • 352 Views
  • 1 CrossRef citations
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Letter
Systemic mastocytosis and lymphoplasmacytic lymphoma: an unusual and intriguing form of SM-AHN
Arturo Bonometti, Emanuela Boveri, Marzia Varettoni, Andrea Ripamonti, Sara Fraticelli, Marco Lucioni, Silvia Zibellini, Chiara Elena, Daniela Pietra, Luca Arcaini & Marco Paulli
Pages: 1782-1785
Published online: 14 Feb 2021
First Page PreviewforSystemic mastocytosis and lymphoplasmacytic lymphoma: an unusual and intriguing form of SM-AHN | Full Text | References | PDF (1.7 MB) | EPUB
  • 185 Views
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Letter
Ibrutinib does not reverse disease- and treatment-related hypogammaglobulinaemia associated with chronic lymphocytic leukemia
Sujoy Khan, Senthilkumar Durairaj, Punyarat Phumphukhieo, Stephen Holding & David Allsup
Pages: 1786-1789
Published online: 17 Feb 2021
First Page PreviewforIbrutinib does not reverse disease- and treatment-related hypogammaglobulinaemia associated with chronic lymphocytic leukemia | Full Text | References | PDF (829.8 KB) | EPUB | Supplemental
  • 184 Views
  • 2 CrossRef citations
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Letter
NPM1-mutant acute myeloid leukemia relapsing as acute lymphoblastic leukemia with clonal persistence of IDH1 mutation
Hari S. Raman, Vignesh Shanmugam, Jingwei Li, David P. Steensma, Annette S. Kim & Marlise R. Luskin
Pages: 1790-1792
Published online: 13 Feb 2021
First Page PreviewforNPM1-mutant acute myeloid leukemia relapsing as acute lymphoblastic leukemia with clonal persistence of IDH1 mutation | Full Text | References | PDF (839.8 KB) | EPUB
  • 156 Views
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