Cancer Biology & Therapy, Volume 13, Issue 13 (2012)

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Cancer Biology & Therapy, Volume 13, Issue 13 (2012)

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Special Article

Article
Patent controversies and court cases
Cancer diagnosis, therapy and prevention
Arsenio M. Fialho & Ananda M. Chakrabarty
Pages: 1229-1234
Published online: 06 Sep 2012
AbstractforPatent controversies and court cases | Full Text | References | PDF (703.7 KB)
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Clinical Study

Article
K-Ras gene mutation status as a prognostic and predictive factor in patients with colorectal cancer undergoing irinotecan- or oxaliplatin-based chemotherapy
Rafał Stec, Lubomir Bodnar, Radosław Charkiewicz, Jan Korniluk, Marta Rokita, Marta Smoter, Marzena Ciechowicz, Lech Chyczewski, Jacek Nikliński, Wojciech Kozłowski & Cezary Szczylik
Pages: 1235-1243
Published online: 22 Aug 2012
AbstractforK-Ras gene mutation status as a prognostic and predictive factor in patients with colorectal cancer undergoing irinotecan- or oxaliplatin-based chemotherapy | Full Text | References | PDF (868.1 KB)
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Research Paper

Article
Oridonin in combination with imatinib exerts synergetic anti-leukemia effect in Ph+ acute lymphoblastic leukemia cells in vitro by inhibiting activation of LYN/mTOR signaling pathway
Yong Guo, Qingqing Shan, Yuping Gong, Juan Lin, Xi Yang & Ruiqing Zhou
Pages: 1244-1254
Published online: 16 Aug 2012
AbstractforOridonin in combination with imatinib exerts synergetic anti-leukemia effect in Ph+ acute lymphoblastic leukemia cells in vitro by inhibiting activation of LYN/mTOR signaling pathway | Full Text | References | PDF (3.6 MB) | Supplemental
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Article
A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling
Lucy Liu, Marina Kritsanida, Prokopios Magiatis, Nicolas Gaboriaud, Yan Wang, Jun Wu, Ralf Buettner, Fan Yang, Sangkil Nam, Leandros Skaltsounis & Richard Jove
Pages: 1255-1261
Published online: 16 Aug 2012
AbstractforA novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling | Full Text | References | PDF (844.3 KB) | Supplemental
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Article
Reporting of preclinical tumor-graft cancer therapeutic studies
Elizabeth Sugar, Adam J. Pascoe & Nilofer Azad
Pages: 1262-1268
Published online: 16 Aug 2012
AbstractforReporting of preclinical tumor-graft cancer therapeutic studies | Full Text | References | PDF (1,022.6 KB) | Supplemental
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Article
Development of a rat model of oral small molecule receptor tyrosine kinase inhibitor-induced diarrhea
Joanne M. Bowen, Bronwen J. Mayo, Erin Plews, Emma Bateman, Andrea M. Stringer, Frances M. Boyle, John W. Finnie & Dorothy M.K. Keefe
Pages: 1269-1275
Published online: 16 Aug 2012
AbstractforDevelopment of a rat model of oral small molecule receptor tyrosine kinase inhibitor-induced diarrhea | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
CD44 ligation with A3D8 antibody induces apoptosis in acute myeloid leukemia cells through binding to CD44s and clustering lipid rafts
Hao Qian, Lijuan Xia, Peixue Ling, Samuel Waxman & Yongkui Jing
Pages: 1276-1283
Published online: 16 Aug 2012
AbstractforCD44 ligation with A3D8 antibody induces apoptosis in acute myeloid leukemia cells through binding to CD44s and clustering lipid rafts | Full Text | References | PDF (1.8 MB)
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Article
The metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer
Alexandra Giatromanolaki, Michael I. Koukourakis, Anastasios Koutsopoulos, Savvas Mendrinos & Efthimios Sivridis
Pages: 1284-1289
Published online: 16 Aug 2012
AbstractforThe metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer | Full Text | References | PDF (1.5 MB)
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Article
A second target of benzamide riboside
Dihydrofolate reductase
Breton Roussel, Nadine Johnson-Farley, John E. Kerrigan, Kathleen W Scotto, Debabrata Banerjee, Krzysztof Felczak, Krzysztof W. Pankiewicz, Murugesan Gounder, HongXia Lin, Emine Ercikan Abali & Joseph R Bertino
Pages: 1290-1298
Published online: 06 Sep 2012
AbstractforA second target of benzamide riboside | Full Text | References | PDF (1.3 MB)
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Article
Preferential induction of apoptotic cell death in melanoma cells as compared with normal keratinocytes using a non-thermal plasma torch
Shoshanna N. Zucker, Jennifer Zirnheld, Archis Bagati, Thomas M. DiSanto, Benjamin Des Soye, Joseph A. Wawrzyniak, Kasra Etemadi, Mikhail Nikiforov & Ronald Berezney
Pages: 1299-1306
Published online: 16 Aug 2012
AbstractforPreferential induction of apoptotic cell death in melanoma cells as compared with normal keratinocytes using a non-thermal plasma torch | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Identification of inositol polyphosphate 4-phosphatase type II as a novel tumor resistance biomarker in human laryngeal cancer HEp-2 cells
Jae-Sung Kim, Hong Shik Yun, Hong-Duck Um, Jong Kuk Park, Kee-Ho Lee, Chang-Mo Kang, Su-Jae Lee & Sang-Gu Hwang
Pages: 1307-1318
Published online: 16 Aug 2012
AbstractforIdentification of inositol polyphosphate 4-phosphatase type II as a novel tumor resistance biomarker in human laryngeal cancer HEp-2 cells | Full Text | References | PDF (1.6 MB)
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Article
Genetic disruption of USP9X sensitizes colorectal cancer cells to 5-fluorouracil
Dennis R. Harris, Alexandra Mims & Fred Bunz
Pages: 1319-1324
Published online: 16 Aug 2012
AbstractforGenetic disruption of USP9X sensitizes colorectal cancer cells to 5-fluorouracil | Full Text | References | PDF (1.8 MB)
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Article
Autophagy limits the cytotoxic effects of the AKT inhibitor AZ7328 in human bladder cancer cells
Rian J. Dickstein, Giovanni Nitti, Colin P. Dinney, Barry R. Davies, Ashish M Kamat & David J McConkey
Pages: 1325-1338
Published online: 16 Aug 2012
AbstractforAutophagy limits the cytotoxic effects of the AKT inhibitor AZ7328 in human bladder cancer cells | Full Text | References | PDF (2.7 MB) | Supplemental
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Article
Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells
Wensheng Yang, Xiaolu Yang, Gregory David & Jay F. Dorsey
Pages: 1339-1348
Published online: 16 Aug 2012
AbstractforDissecting the complex regulation of Mad4 in glioblastoma multiforme cells | Full Text | References | PDF (2 MB)
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