Cancer Biology & Therapy, Volume 16, Issue 9 (2015)

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Cancer Biology & Therapy, Volume 16, Issue 9 (2015)

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Clinical Studies

Article
Impact of EGFR and p53 expressions on survival and quality of life in locally advanced oral squamous cell carcinoma patients treated with chemoradiation
Seema Gupta, Huma Khan, Vandana Singh Kushwaha, Nuzhat Husain, MPS Negi, Ashim Ghatak & MLB Bhatt
Pages: 1269-1280
Published online: 17 Sep 2015
AbstractforImpact of EGFR and p53 expressions on survival and quality of life in locally advanced oral squamous cell carcinoma patients treated with chemoradiation | Full Text | References | PDF (494 KB)
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Article
Elevated ARG1 expression in primary monocytes-derived macrophages as a predictor of radiation-induced acute skin toxicities in early breast cancer patients
Karen Jung, Siham Sabri, John Hanson, Yaoxian Xu, Ying Wayne Wang, Raymond Lai & Bassam S Abdulkarim
Pages: 1281-1288
Published online: 17 Sep 2015
AbstractforElevated ARG1 expression in primary monocytes-derived macrophages as a predictor of radiation-induced acute skin toxicities in early breast cancer patients | Full Text | References | PDF (202.3 KB) | Supplemental
  • 1965 Views
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Article
Detection of KRAS mutations in circulating tumor cells from patients with metastatic colorectal cancer
Marcilei EC Buim, Marcello F Fanelli, Virgilio S Souza, Juliana Romero, Emne A Abdallah, Celso AL Mello, Vanessa Alves, Luciana MM Ocea, Natália B Mingues, Paula NVP Barbosa, Chiang J Tyng, Rubens Chojniak & Ludmilla TD Chinen
Pages: 1289-1295
Published online: 12 Aug 2015
AbstractforDetection of KRAS mutations in circulating tumor cells from patients with metastatic colorectal cancer | Full Text | References | PDF (153.7 KB)
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Research Papers

Article
Decrease of mitochondrial p53 during late apoptosis is linked to its dephosphorylation on serine 20
Cédric Castrogiovanni, Marie Vandaudenard, Béranger Waterschoot, Olivier De Backer & Patrick Dumont
Pages: 1296-1307
Published online: 17 Sep 2015
AbstractforDecrease of mitochondrial p53 during late apoptosis is linked to its dephosphorylation on serine 20 | Full Text | References | PDF (754.1 KB) | Supplemental
  • 821 Views
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Article
MiR-302c-3p suppresses invasion and proliferation of glioma cells via down-regulating metadherin (MTDH) expression
Yonghong Wang, Yujun Wei, Haibo Tong, Laizhao Chen, Yimin Fan, Yuchen Ji, Wenqing Jia, Dongkang Liu & Guihuai Wang
Pages: 1308-1315
Published online: 08 Aug 2015
AbstractforMiR-302c-3p suppresses invasion and proliferation of glioma cells via down-regulating metadherin (MTDH) expression | Full Text | References | PDF (597.3 KB)
  • 793 Views
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Article
KIFC1 is a novel potential therapeutic target for breast cancer
Yonghe Li, Wenyan Lu, Dongquan Chen, Rebecca J Boohaker, Ling Zhai, Indira Padmalayam, Krister Wennerberg, Bo Xu & Wei Zhang
Pages: 1316-1322
Published online: 08 Aug 2015
AbstractforKIFC1 is a novel potential therapeutic target for breast cancer | Full Text | References | PDF (538.1 KB)
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Article
Generation of CD8+ T cells expressing two additional T-cell receptors (TETARs) for personalised melanoma therapy
Sandra Höfflin, Sabrina Prommersberger, Ugur Uslu, Gerold Schuler, Christopher W Schmidt, Volker Lennerz, Jan Dörrie & Niels Schaft
Pages: 1323-1331
Published online: 08 Aug 2015
AbstractforGeneration of CD8+ T cells expressing two additional T-cell receptors (TETARs) for personalised melanoma therapy | Full Text | References | PDF (423.8 KB) | Supplemental
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Article
RNAi-mediated silencing of AQP1 expression inhibited the proliferation, invasion and tumorigenesis of osteosarcoma cells
Zhong Wu, Shaohua Li, Jie Liu, Yongzhen Shi, Jianguang Wang, Dong Chen, Linjie Luo, Yongqiang Qian, Xiang Huang & Hua Wang
Pages: 1332-1340
Published online: 07 Aug 2015
AbstractforRNAi-mediated silencing of AQP1 expression inhibited the proliferation, invasion and tumorigenesis of osteosarcoma cells | Full Text | References | PDF (930.7 KB)
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Article
Inhibition of class IA PI3K enzymes in non-small cell lung cancer cells uncovers functional compensation among isoforms
Christopher Stamatkin, Kelley L Ratermann, Colleen W Overley & Esther P Black
Pages: 1341-1352
Published online: 08 Aug 2015
AbstractforInhibition of class IA PI3K enzymes in non-small cell lung cancer cells uncovers functional compensation among isoforms | Full Text | References | PDF (721.3 KB) | Supplemental
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Article
Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma
Karin Melanie Cabanillas Stanchi, Gernot Bruchelt, Rupert Handgretinger & Ursula Holzer
Pages: 1353-1363
Published online: 08 Aug 2015
AbstractforNifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma | Full Text | References | PDF (592.5 KB) | Supplemental
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Article
β-Adrenergic receptors suppress Rap1B prenylation and promote the metastatic phenotype in breast cancer cells
Jessica M Wilson, Ellen Lorimer, Michael D Tyburski & Carol L Williams
Pages: 1364-1374
Published online: 08 Aug 2015
Abstractforβ-Adrenergic receptors suppress Rap1B prenylation and promote the metastatic phenotype in breast cancer cells | Full Text | References | PDF (973.4 KB) | Supplemental
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Article
c-Myc modulation: a key role in melanoma drug response
Annalisa Fico, Daniela Alfano, Anna Valentino, Valeria Vasta, Ernesta Cavalcanti, Salvatore Travali, Eduardo J Patriarca & Emilia Caputo
Pages: 1375-1386
Published online: 29 May 2015
Abstractforc-Myc modulation: a key role in melanoma drug response | Full Text | References | PDF (1 MB) | Supplemental
  • 982 Views
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Article
miRNA profiling in vitreous humor, vitreal exosomes and serum from uveal melanoma patients: Pathological and diagnostic implications
Marco Ragusa, Cristina Barbagallo, Luisa Statello, Rosario Caltabiano, Andrea Russo, Lidia Puzzo, Teresio Avitabile, Antonio Longo, Mario D Toro, Davide Barbagallo, Hadi Valadi, Cinzia Di Pietro, Michele Purrello & Michele Reibaldi
Pages: 1387-1396
Published online: 12 Aug 2015
AbstractformiRNA profiling in vitreous humor, vitreal exosomes and serum from uveal melanoma patients: Pathological and diagnostic implications | Full Text | References | PDF (561.1 KB) | Supplemental
  • 2883 Views
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Article
Pixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions
Neil Beeharry, Andrea Ghelli Luserna Di Rora, Mitchell R Smith & Timothy J Yen
Pages: 1397-1406
Published online: 17 Sep 2015
AbstractforPixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions | Full Text | References | PDF (856.5 KB) | Supplemental
  • 1345 Views
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Article
Salvianolic acid A reverses the paclitaxel resistance and inhibits the migration and invasion abilities of human breast cancer cells by inactivating transgelin 2
Xiaowei Zheng, Siying Chen, Qianting Yang, Jiangxia Cai, Weipeng Zhang, Haisheng You, Jianfeng Xing & Yalin Dong
Pages: 1407-1414
Published online: 17 Sep 2015
AbstractforSalvianolic acid A reverses the paclitaxel resistance and inhibits the migration and invasion abilities of human breast cancer cells by inactivating transgelin 2 | Full Text | References | PDF (803 KB)
  • 1474 Views
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Article
A targeted IL-15 fusion protein with potent anti-tumor activity
Siqi Chen, Qiang Huang, Jiayu Liu, Jieyu Xing, Ning Zhang, Yawei Liu, Zhong Wang & Qing Li
Pages: 1415-1421
Published online: 20 Aug 2015
AbstractforA targeted IL-15 fusion protein with potent anti-tumor activity | Full Text | References | PDF (574 KB) | Supplemental
  • 2650 Views
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Article
Efficacy of the HSP70 inhibitor PET-16 in multiple myeloma
Charvann K Bailey, Anna Budina-Kolomets, Maureen E Murphy & Yulia Nefedova
Pages: 1422-1426
Published online: 11 Aug 2015
AbstractforEfficacy of the HSP70 inhibitor PET-16 in multiple myeloma | Full Text | References | PDF (209.9 KB)
  • 1020 Views
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