Cell Cycle, Volume 11, Issue 6 (2012)

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Cell Cycle, Volume 11, Issue 6 (2012)

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Editorials: Cell Cycle Features

Editorial
The cyclin K/Cdk12 complex
An emerging new player in the maintenance of genome stability
Dalibor Blazek
Pages: 1049-1050
Published online: 15 Mar 2012
AbstractforThe cyclin K/Cdk12 complex | Full Text | References | PDF (172.4 KB)
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Editorial
Adaptation in a eukaryotic pathway
Combining experiments with modeling
Wouter-Jan Rappel & Richard Firtel
Pages: 1051-1052
Published online: 15 Mar 2012
AbstractforAdaptation in a eukaryotic pathway | Full Text | References | PDF (249.3 KB)
  • 406 Views
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Editorial
Glycogen synthase kinase (GSK)-3 and mammalian target of rapamycin complex 1 (mTORC1) cooperate to regulate protein S6 kinase 1 (S6K1)
Sejeong Shin, Laura Wolgamott & Sang-Oh Yoon
Pages: 1053-1054
Published online: 15 Mar 2012
AbstractforGlycogen synthase kinase (GSK)-3 and mammalian target of rapamycin complex 1 (mTORC1) cooperate to regulate protein S6 kinase 1 (S6K1) | PDF (304.5 KB)
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Editorial
Finding a needle in the haystack: Recognition of DNA damage by collaboration between DNA repair proteins able to perform DNA charge transport
Robert M. Brosh
Pages: 1055-1056
Published online: 15 Mar 2012
CitationforFinding a needle in the haystack: Recognition of DNA damage by collaboration between DNA repair proteins able to perform DNA charge transport | PDF (177 KB)
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Cell Cycle News & Views

A role of miR-33 for cell cycle progression and cell proliferation
Yasuko Iwakiri
Page: 1057
Published online: 15 Mar 2012
AbstractforA role of miR-33 for cell cycle progression and cell proliferation | PDF (637.6 KB)
  • 340 Views
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Metformin and reprogramming into iPSCs
Manuel Serrano
Page: 1058
Published online: 15 Mar 2012
AbstractforMetformin and reprogramming into iPSCs | PDF (627.1 KB)
  • 396 Views
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Reverse Warburg: Straight to cancer
Lorenzo Galluzzi, Oliver Kepp & Guido Kroemer
Page: 1059
Published online: 15 Mar 2012
AbstractforReverse Warburg: Straight to cancer | PDF (627.1 KB)
  • 495 Views
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MiR-33 connects cholesterol to the cell cycle
Sachi Inukai & Frank J. Slack
Pages: 1060-1061
Published online: 15 Mar 2012
AbstractforMiR-33 connects cholesterol to the cell cycle | Full Text | References | PDF (627.1 KB)
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Extra Views

p97/VCP- and Lys48-linked polyubiquitination form a new signaling pathway in DNA damage response
Kristijan Ramadan
Pages: 1062-1069
Published online: 15 Mar 2012
Abstractforp97/VCP- and Lys48-linked polyubiquitination form a new signaling pathway in DNA damage response | PDF (1.5 MB)
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Regulation of oxidative DNA damage repair: The adenine:8-oxo-guanine problem
Enni Markkanen, Ulrich Hübscher & Barbara van Loon
Pages: 1070-1075
Published online: 15 Mar 2012
AbstractforRegulation of oxidative DNA damage repair: The adenine:8-oxo-guanine problem | PDF (578.8 KB)
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Mining the cancer genome uncovers therapeutic activity of EphA7 against lymphoma
Elisa Oricchio & Hans-Guido Wendel
Pages: 1076-1080
Published online: 15 Mar 2012
AbstractforMining the cancer genome uncovers therapeutic activity of EphA7 against lymphoma | Full Text | References | PDF (375.2 KB)
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Vitamin D has wide regulatory effects on histone demethylase genes
Fábio Pereira, Antonio Barbáchano, Prashant K. Singh, Moray J. Campbell, Alberto Muñoz & María Jesús Larriba
Pages: 1081-1089
Published online: 15 Mar 2012
AbstractforVitamin D has wide regulatory effects on histone demethylase genes | PDF (1.3 MB) | Supplemental
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Review

Review Article
YAP oncogene overexpression supercharges colon cancer proliferation
Joseph Avruch, Dawang Zhou & Nabeel Bardeesy
Pages: 1090-1096
Published online: 15 Mar 2012
AbstractforYAP oncogene overexpression supercharges colon cancer proliferation | Full Text | References | PDF (436.8 KB)
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Review Article
Translational control of cell fate: From integration of environmental signals to breaching anticancer defense
Peter B. Bitterman & Vitaly A. Polunovsky
Pages: 1097-1107
Published online: 15 Mar 2012
AbstractforTranslational control of cell fate: From integration of environmental signals to breaching anticancer defense | PDF (803.1 KB)
  • 422 Views
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Report

Article
Using the “reverse Warburg effect” to identify high-risk breast cancer patients
Stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers
Agnieszka K. Witkiewicz, Diana Whitaker-Menezes, Abhijit Dasgupta, Nancy J. Philp, Zhao Lin, Ricardo Gandara, Sharon Sneddon, Ubaldo E. Martinez-Outschoorn, Federica Sotgia & Michael P. Lisanti
Pages: 1108-1117
Published online: 15 Mar 2012
AbstractforUsing the “reverse Warburg effect” to identify high-risk breast cancer patients | Full Text | References | PDF (1.9 MB)
  • 3739 Views
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Article
SENP1 deficiency promotes ER stress-induced apoptosis by increasing XBP1 SUMOylation
Zhou Jiang, Qiuju Fan, Zhening Zhang, Yanqiong Zou, Rong Cai, Qi Wang, Yong Zuo & Jinke Cheng
Pages: 1118-1122
Published online: 15 Mar 2012
AbstractforSENP1 deficiency promotes ER stress-induced apoptosis by increasing XBP1 SUMOylation | PDF (849.8 KB)
  • 948 Views
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Article
The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer
Jayoung Kim, Wun-Jae Kim, Zhiqian Liu, Massimo Loda & Michael R. Freeman
Pages: 1123-1130
Published online: 15 Mar 2012
AbstractforThe ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer | Full Text | References | PDF (2.5 MB)
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Article
Rad18 is a transcriptional target of E2F3
Lakshman Varanasi, Phi M. Do, Elzbieta Goluszko & Luis A. Martinez
Pages: 1131-1141
Published online: 15 Mar 2012
AbstractforRad18 is a transcriptional target of E2F3 | PDF (1.2 MB) | Supplemental
  • 557 Views
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Article
The ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions
Orsolya Leidecker, Ivan Matic, Bidesh Mahata, Emmanuelle Pion & Dimitris P. Xirodimas
Pages: 1142-1150
Published online: 15 Mar 2012
AbstractforThe ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions | PDF (1,018.4 KB) | Supplemental
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Article
Origin of metastases: Subspecies of cancers generated by intrinsic karyotypic variations
Peter Duesberg, Christine Iacobuzio-Donahue, Jacqueline A. Brosnan, Amanda McCormack, Daniele Mandrioli & Lewis Chen
Pages: 1151-1166
Published online: 15 Mar 2012
AbstractforOrigin of metastases: Subspecies of cancers generated by intrinsic karyotypic variations | PDF (2.2 MB)
  • 543 Views
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Article
Dynamic inhibition of ATM kinase provides a strategy for glioblastoma multiforme radiosensitization and growth control
Sarah E. Golding, Elizabeth Rosenberg, Bret R. Adams, Shayalini Wignarajah, Jason M. Beckta, Mark J. O’Connor & Kristoffer Valerie
Pages: 1167-1173
Published online: 15 Mar 2012
AbstractforDynamic inhibition of ATM kinase provides a strategy for glioblastoma multiforme radiosensitization and growth control | Full Text | References | PDF (906.4 KB) | Supplemental
  • 1690 Views
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Article
Saquinavir-NO-targeted S6 protein mediates sensitivity of androgen-dependent prostate cancer cells to TRAIL
Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Svetlana Dinic, Nevena Grdovic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Salvatore Tumino, Paolo Fagone, Katia Mangano, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey & Ferdinando Nicoletti
Pages: 1174-1182
Published online: 15 Mar 2012
AbstractforSaquinavir-NO-targeted S6 protein mediates sensitivity of androgen-dependent prostate cancer cells to TRAIL | PDF (812.2 KB)
  • 277 Views
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Article
Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts
Sanjay Kumar, Hae Yong Yoo, Akiko Kumagai, Anna Shevchenko, Andrej Shevchenko & William G. Dunphy
Pages: 1183-1194
Published online: 15 Mar 2012
AbstractforRole for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts | Full Text | References | PDF (1 MB) | Supplemental
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Article
p38α MAPK regulates myocardial regeneration in zebrafish
Chris Jopling, Guillermo Suñè, Cristina Morera & Juan Carlos Izpisua Belmote
Pages: 1195-1201
Published online: 15 Mar 2012
Abstractforp38α MAPK regulates myocardial regeneration in zebrafish | Full Text | References | PDF (2.1 MB)
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Article
Flavopiridol induces phosphorylation of AKT in a human glioblastoma cell line, in contrast to siRNA-mediated silencing of Cdk9: Implications for drug design and development
Valentina Caracciolo, Giulio Laurenti, Gaetano Romano, Vincenzo Carnevale, Anna Maria Cimini, Catena Crozier-Fitzgerald, Emilio Gentile Warschauer, Giuseppe Russo & Antonio Giordano
Pages: 1202-1216
Published online: 15 Mar 2012
AbstractforFlavopiridol induces phosphorylation of AKT in a human glioblastoma cell line, in contrast to siRNA-mediated silencing of Cdk9: Implications for drug design and development | PDF (3.1 MB)
  • 872 Views
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Article
HIV-1 Tat impairs cell cycle control by targeting the Tip60, Plk1 and cyclin B1 ternary complex
Shi-Meng Zhang, Maoyong Song, Tian-Yi Yang, Rong Fan, Xiao-Dan Liu & Ping-Kun Zhou
Pages: 1217-1234
Published online: 15 Mar 2012
AbstractforHIV-1 Tat impairs cell cycle control by targeting the Tip60, Plk1 and cyclin B1 ternary complex | PDF (11.9 MB) | Supplemental
  • 709 Views
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Article
Metformin lowers the threshold for stress-induced senescence: A role for the microRNA-200 family and miR-205
Sílvia Cufí, Alejandro Vazquez-Martin, Cristina Oliveras-Ferraros, Rosa Quirantes, Antonio Segura-Carretero, Vicente Micol, Jorge Joven, Joaquim Bosch-Barrera, Sonia Del Barco , Begoña Martin-Castillo, Luciano Vellon & Javier A. Menendez
Pages: 1235-1246
Published online: 15 Mar 2012
AbstractforMetformin lowers the threshold for stress-induced senescence: A role for the microRNA-200 family and miR-205 | PDF (5 MB)
  • 1619 Views
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Article
Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation
Yiping Huang, Rafael Guerrero-Preston & Edward A. Ratovitski
Pages: 1247-1259
Published online: 15 Mar 2012
AbstractforPhospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation | Full Text | References | PDF (1.3 MB) | Supplemental
  • 1313 Views
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