Cell Cycle, Volume 9, Issue 17 (2010)

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Cell Cycle, Volume 9, Issue 17 (2010)

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Editorials: Cell Cycle Features

Editorial
γ-H2AX: Applications for the evaluation of telomerase-based cancer therapy
Asako J. Nakamura, Christophe E. Redon & William M. Bonner
Pages: 3385-3386
Published online: 01 Sep 2010
Citationfor γ-H2AX: Applications for the evaluation of telomerase-based cancer therapy | PDF (538.1 KB)
  • 195 Views
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Editorial
Methylation of polyphenols with vicinal hydroxyl groups: A protection pathway increasing organismal lifespan
Birgit Knab & Heinz D. Osiewacz
Pages: 3387-3388
Published online: 01 Sep 2010
Abstractfor Methylation of polyphenols with vicinal hydroxyl groups: A protection pathway increasing organismal lifespan | PDF (206.4 KB)
  • 249 Views
  • 11 CrossRef citations
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Editorial
Catching a glimpse of nucleosome dynamics
Roger B. Deal & Steven Henikoff
Pages: 3389-3390
Published online: 01 Sep 2010
Abstractfor Catching a glimpse of nucleosome dynamics | PDF (466.5 KB)
  • 213 Views
  • 6 CrossRef citations
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Editorial
HOTAIR: Flight of noncoding RNAs in cancer metastasis
Yue Wan & Howard Y. Chang
Pages: 3391-3392
Published online: 01 Sep 2010
Citationfor HOTAIR: Flight of noncoding RNAs in cancer metastasis | PDF (300.8 KB)
  • 489 Views
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Editorial
4-Hydroxynonenal and fat storage: A paradoxical pro-obesity mechanism?
Piotr Zimniak
Pages: 3393-3394
Published online: 01 Sep 2010
Citationfor 4-Hydroxynonenal and fat storage: A paradoxical pro-obesity mechanism? | PDF (281.3 KB)
  • 365 Views
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News & Views

News
Cytometry of the cell cycle: In search for perfect methodology for DNA content analysis in tissue specimens
Zbigniew Darzynkiewicz
Pages: 3395-3396
Published online: 01 Sep 2010
First Page PreviewforCytometry of the cell cycle: In search for perfect methodology for DNA content analysis in tissue specimens | PDF (370.3 KB)
  • 167 Views
  • 3 CrossRef citations
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News
The primary role of intracellular free Mg2+ in regulating cell growth
Harry Rubin
Pages: 3396-3397
Published online: 01 Sep 2010
Abstractfor The primary role of intracellular free Mg2+ in regulating cell growth | PDF (158.3 KB)
  • 238 Views
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News
A role for miR-33 in p53 regulation: New perspectives for hematopoietic stem cell research
José Javier Fuster & Vicente Andrés
Pages: 3397-3398
Published online: 01 Sep 2010
Abstractfor A role for miR-33 in p53 regulation: New perspectives for hematopoietic stem cell research | PDF (156.7 KB)
  • 311 Views
  • 3 CrossRef citations
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News
Stuck in a checkpoint: A role for Ras deregulation in DNA damage checkpoint recovery
Amy S. Gladfelter
Page: 3398
Published online: 01 Sep 2010
Abstractfor Stuck in a checkpoint: A role for Ras deregulation in DNA damage checkpoint recovery | PDF (149.7 KB)
  • 200 Views
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News
TRPM7 and magnesium, metabolism, mitosis: An old path with new pebbles
Federica I. Wolf & Valentina Trapani
Page: 3399
Published online: 01 Sep 2010
Abstractfor TRPM7 and magnesium, metabolism, mitosis: An old path with new pebbles | PDF (151.1 KB)
  • 370 Views
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News
Differentiating the interferon pathway
Bryan R. G. Williams
Page: 3400
Published online: 01 Sep 2010
Abstractfor Differentiating the interferon pathway | PDF (146.4 KB)
  • 147 Views
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Extra Views

Does Huntingtin play a role in selective macroautophagy?
Joan S. Steffan
Pages: 3401-3413
Published online: 01 Sep 2010
Abstractfor Does Huntingtin play a role in selective macroautophagy? | Full Text | References | PDF (1.3 MB) | Supplemental
  • 2359 Views
  • 56 CrossRef citations
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Rem2 GTPase controls proliferation and apoptosis of neurons during embryo development
Michael J. Edel, Stephanie Boue, Cristina Menchón, Adriana Sanchez-Danes & Juan Carlos Izpisua Belmote
Pages: 3414-3422
Published online: 01 Sep 2010
Abstractfor Rem2 GTPase controls proliferation and apoptosis of neurons during embryo development | PDF (3.2 MB)
  • 331 Views
  • 11 CrossRef citations
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IL-6, a risk factor for hepatocellular carcinoma: FLLL32 inhibits IL-6-Induced STAT3 phosphorylation in human hepatocellular cancer cells
Yan Liu, James Fuchs, Chenglong Li & Jiayuh Lin
Pages: 3423-3427
Published online: 01 Sep 2010
Abstractfor IL-6, a risk factor for hepatocellular carcinoma: FLLL32 inhibits IL-6-Induced STAT3 phosphorylation in human hepatocellular cancer cells | PDF (953.7 KB)
  • 786 Views
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Disparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genes
Nathan P. Gomes & Joaquín M. Espinosa
Pages: 3428-3437
Published online: 01 Sep 2010
Abstractfor Disparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genes | Full Text | References | PDF (2.7 MB) | Supplemental
  • 643 Views
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Perspective

Are the conspicuous interdependences of fecundity, longevity and cognitive abilities in humans caused in part by p53?
Klaus Roemer
Pages: 3438-3441
Published online: 01 Sep 2010
Abstractfor Are the conspicuous interdependences of fecundity, longevity and cognitive abilities in humans caused in part by p53? | PDF (297 KB)
  • 170 Views
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Review

Review Article
Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure
Gerald W. Dorn
Pages: 3442-3448
Published online: 01 Sep 2010
Abstractfor Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure | Full Text | References | PDF (711.4 KB)
  • 693 Views
  • 20 CrossRef citations
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Review Article
Hedgehog pathway activation in chronic myeloid leukemia: A promise for a novel combination therapeutic approach?
Zainab Jagani, Marion Dorsch & Markus Warmuth
Pages: 3449-3456
Published online: 01 Sep 2010
Abstractfor Hedgehog pathway activation in chronic myeloid leukemia: A promise for a novel combination therapeutic approach? | PDF (482 KB)
  • 729 Views
  • 37 CrossRef citations
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Review Article
The oncogenic role of the ETS transcription factors MEF and ERG
Goro Sashida, Elena Bazzoli, Silvia Menendez & Nimer Stephen D.
Pages: 3457-3459
Published online: 01 Sep 2010
AbstractforThe oncogenic role of the ETS transcription factors MEF and ERG | Full Text | References | PDF (369.2 KB)
  • 1152 Views
  • 12 CrossRef citations
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Review Article
The DNA-dependent protein kinase (DNA-PK): More than just a case of making ends meet?
Richard Hill & Patrick W. Lee
Pages: 3460-3469
Published online: 01 Sep 2010
Abstractfor The DNA-dependent protein kinase (DNA-PK): More than just a case of making ends meet? | PDF (1,019.5 KB)
  • 1694 Views
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Review Article
Targeting autophagy to fight hematopoietic malignancies
Alexandre Puissant, Guillaume Robert & Patrick Auberger
Pages: 3470-3478
Published online: 01 Sep 2010
Abstractfor Targeting autophagy to fight hematopoietic malignancies | PDF (1.8 MB)
  • 998 Views
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Review Article
Quantitative phosphoproteomics
New technologies and applications in the DNA damage response
Huilin Zhou, Claudio Albuquerque, Jason Liang, Raymond T. Suhandynata & Stephanie Weng
Pages: 3479-3484
Published online: 01 Sep 2010
Abstractfor Quantitative phosphoproteomics | Full Text | References | PDF (697.9 KB)
  • 685 Views
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Report

Article
The autophagic tumor stroma model of cancer
Role of oxidative stress and ketone production in fueling tumor cell metabolism
Stephanos Pavlides, Aristotelis Tsirigos, Gemma Migneco, Diana Whitaker-Menezes, Barbara Chiavarina, Neal Flomenberg, Philippe G. Frank, Mathew C. Casimiro, Chenguang Wang, Richard G. Pestell, Ubaldo E. Martinez-Outschoorn, Anthony Howell, Federica Sotgia & Michael P. Lisanti
Pages: 3485-3505
Published online: 01 Sep 2010
AbstractforThe autophagic tumor stroma model of cancer | Full Text | References | PDF (2.3 MB) | Supplemental
  • 3766 Views
  • 196 CrossRef citations
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Article
Ketones and lactate “fuel” tumor growth and metastasis
Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
Gloria Bonuccelli, Aristotelis Tsirigos, Diana Whitaker-Menezes, Stephanos Pavlides, Richard G. Pestell, Barbara Chiavarina, Philippe G. Frank, Neal Flomenberg, Anthony Howell, Ubaldo E. Martinez-Outschoorn, Federica Sotgia & Michael P. Lisanti
Pages: 3506-3514
Published online: 01 Sep 2010
Abstractfor Ketones and lactate “fuel” tumor growth and metastasis | Full Text | References | PDF (1.2 MB) | Supplemental
  • 12619 Views
  • 436 CrossRef citations
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Article
Autophagy in cancer associated fibroblasts promotes tumor cell survival
Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment
Ubaldo E. Martinez-Outschoorn, Casey Trimmer, Zhao Lin, Diana Whitaker-Menezes , Barbara Chiavarina, Jie Zhou, Chenguang Wang, Stephanos Pavlides, Maria P. Martinez-Cantarin, Franco Capozza, Agnieszka K. Witkiewicz, Neal Flomenberg, Anthony Howell, Richard G. Pestell, Jaime Caro, Michael P. Lisanti & Federica Sotgia
Pages: 3515-3533
Published online: 01 Sep 2010
Abstractfor Autophagy in cancer associated fibroblasts promotes tumor cell survival | Full Text | References | PDF (4.5 MB) | Supplemental
  • 4198 Views
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Article
HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells
Autophagy drives compartment-specific oncogenesis
Barbara Chiavarina, Diana Whitaker-Menezes, Gemma Migneco, Ubaldo E. Martinez-Outschoorn, Stephanos Pavlides, Anthony Howell, Herbert B. Tanowitz, Mathew C. Casimiro, Chenguang Wang, Richard G. Pestell, Philip Grieshaber, Jaime Caro, Federica Sotgia & Michael P. Lisanti
Pages: 3534-3551
Published online: 01 Sep 2010
Abstractfor HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells | Full Text | References | PDF (4 MB) | Supplemental
  • 3452 Views
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Article
Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells
Ling-Ling Chen, Li Yang & Gordon Carmichael
Pages: 3552-3564
Published online: 01 Sep 2010
Abstractfor Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells | Full Text | References | PDF (3.1 MB) | Supplemental
  • 1927 Views
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Article
TRPM7 regulates quiescent/proliferative metabolic transitions in lymphocytes
Jaya Sahni, Richard Tamura, Ian R. Sweet & Andrew M. Scharenberg
Pages: 3565-3574
Published online: 01 Sep 2010
Abstractfor TRPM7 regulates quiescent/proliferative metabolic transitions in lymphocytes | Full Text | References | PDF (3.9 MB) | Supplemental
  • 793 Views
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Article
Evidence for a differential modulation of p53-phosphorylating kinases by the cyclin-dependent kinase inhibitor p21WAFI/C1P1
Denise Neise, Dennis Sohn, Wilfried Budach & Reiner U. Jänicke
Pages: 3575-3583
Published online: 01 Sep 2010
Abstractfor Evidence for a differential modulation of p53-phosphorylating kinases by the cyclin-dependent kinase inhibitor p21WAFI/C1P1 | PDF (2.1 MB)
  • 179 Views
  • 6 CrossRef citations
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Article
A rapid and optimization-free procedure allows the in vivo detection of subtle cell cycle and ploidy alterations in tissues by flow cytometry
Christina Heinlein, Wolfgang Deppert, Antony Braithwaite & Daniel Speidel
Pages: 3584-3590
Published online: 01 Sep 2010
Abstractfor A rapid and optimization-free procedure allows the in vivo detection of subtle cell cycle and ploidy alterations in tissues by flow cytometry | Full Text | References | PDF (3.8 MB)
  • 1133 Views
  • 22 CrossRef citations
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Article
MASTL is the human ortholog of Greatwall kinase that facilitates mitotic entry, anaphase and cytokinesis
Erik Voets & Rob M.F. Wolthuis
Pages: 3591-3601
Published online: 01 Sep 2010
Abstractfor MASTL is the human ortholog of Greatwall kinase that facilitates mitotic entry, anaphase and cytokinesis | PDF (4.1 MB)
  • 1197 Views
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Article
H2AX post-translational modifications in the ionizing radiation response and homologous recombination
Anyong Xie, Shobu Odate, Gurushankar Chandramouly & Ralph A. Scully
Pages: 3602-3610
Published online: 01 Sep 2010
AbstractforH2AX post-translational modifications in the ionizing radiation response and homologous recombination | Full Text | References | PDF (1.2 MB) | Supplemental
  • 1124 Views
  • 39 CrossRef citations
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Article
The Lrs4-Csm1 monopolin complex associates with kinetochores during anaphase and is required for accurate chromosome segregation
Ilana Brito, Fernando Monje-Casas & Angelika Amon
Pages: 3611-3618
Published online: 01 Sep 2010
Abstractfor The Lrs4-Csm1 monopolin complex associates with kinetochores during anaphase and is required for accurate chromosome segregation | Full Text | References | PDF (2.9 MB) | Supplemental
  • 684 Views
  • 16 CrossRef citations
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Article
Laterally attached kinetochores recruit the checkpoint protein Bub1, but satisfy the spindle checkpoint
Michelle M. Shimogawa, Megan M. Wargacki, Eric G. Muller & Trisha N. Davis
Pages: 3619-3628
Published online: 01 Sep 2010
Abstractfor Laterally attached kinetochores recruit the checkpoint protein Bub1, but satisfy the spindle checkpoint | Full Text | References | PDF (2 MB)
  • 636 Views
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Letter to the Editor

Letter
Localization of CDK5 in the midbody and increased aneuploidy in CDK5-/- cells
Ki-Young Lee, Ashley Mummery, John Park, Hassan Tariq & Jesusa L. Rosales
Pages: 3629-3630
Published online: 01 Sep 2010
Citationfor Localization of CDK5 in the midbody and increased aneuploidy in CDK5-/- cells | PDF (491.3 KB)
  • 183 Views
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