OncoImmunology, Volume 4, Issue 6 (2015)

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OncoImmunology, Volume 4, Issue 6 (2015)

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Editorial

Immunotherapy of hematological cancers: PD-1 blockade for the treatment of Hodgkin's lymphoma
Guido Kroemer & Lorenzo Galluzzi
Article: e1008853
Published online: 22 May 2015
AbstractforImmunotherapy of hematological cancers: PD-1 blockade for the treatment of Hodgkin's lymphoma | Full Text | References | PDF (63.5 KB)
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Point of View

Article
γδ T cells and epigenetic drugs: A useful merger in cancer immunotherapy?
Jaydeep Bhat & Dieter Kabelitz
Article: e1006088
Published online: 22 May 2015
Abstractforγδ T cells and epigenetic drugs: A useful merger in cancer immunotherapy? | Full Text | References | PDF (184.1 KB)
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Brief Report

Brief Report
Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment
Kirsten Ridder, Alexandra Sevko, Janina Heide, Maria Dams, Anne-Kathleen Rupp, Jadranka Macas, Julia Starmann, Marc Tjwa, Karl H Plate, Holger Sültmann, Peter Altevogt, Viktor Umansky & Stefan Momma
Article: e1008371
Published online: 22 May 2015
AbstractforExtracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment | Full Text | References | PDF (636.7 KB) | Supplemental
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Author's View

Article
Immune checkpoint blockade in microsatellite instable colorectal cancers: Back to the clinic
Franck Housseau & Nicolas J Llosa
Article: e1008858
Published online: 22 May 2015
AbstractforImmune checkpoint blockade in microsatellite instable colorectal cancers: Back to the clinic | Full Text | References | PDF (207.1 KB)
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Article
Delineating CSF-1-dependent regulation of myeloid cell diversity in tumors
Amy-Jo Casbon, Marja Lohela & Zena Werb
Article: e1008871
Published online: 22 May 2015
AbstractforDelineating CSF-1-dependent regulation of myeloid cell diversity in tumors | Full Text | References | PDF (197.4 KB)
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Article
Improving clinical benefit for prostate cancer patients through the combination of androgen deprivation and immunotherapy
Anna R Kwilas, Sofia R Gameiro, Peter S Kim, Anthony S Malamas & James W Hodge
Article: e1009303
Published online: 22 May 2015
AbstractforImproving clinical benefit for prostate cancer patients through the combination of androgen deprivation and immunotherapy | Full Text | References | PDF (280.4 KB)
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Article
The crosstalk between acinar cells with Kras mutations and M1-polarized macrophages leads to initiation of pancreatic precancerous lesions
Peter Storz
Article: e1008794
Published online: 22 May 2015
AbstractforThe crosstalk between acinar cells with Kras mutations and M1-polarized macrophages leads to initiation of pancreatic precancerous lesions | Full Text | References | PDF (162.4 KB)
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Article
CD14+ macrophage-like cells as the linchpin of cervical cancer perpetrated immune suppression and early metastatic spread: A new therapeutic lead?
A Marijne Heeren, Gemma G Kenter, Ekaterina S Jordanova & Tanja D de Gruijl
Article: e1009296
Published online: 22 May 2015
AbstractforCD14+ macrophage-like cells as the linchpin of cervical cancer perpetrated immune suppression and early metastatic spread: A new therapeutic lead? | Full Text | References | PDF (217.1 KB)
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Article
Regramming myeloid responses to improve cancer immunotherapy
Yu Zhu, William G Hawkins & David G DeNardo
Article: e974399
Published online: 22 May 2015
AbstractforRegramming myeloid responses to improve cancer immunotherapy | Full Text | References | PDF (222.2 KB)
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Article
Implications of understanding the signaling, cellular, and cytotoxic mechanisms afforded by afucosylated antibodies
Scot D Liu & John B Lowe
Article: e1009288
Published online: 22 May 2015
AbstractforImplications of understanding the signaling, cellular, and cytotoxic mechanisms afforded by afucosylated antibodies | Full Text | References | PDF (121.1 KB)
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Article
T cell receptor-therapy in HBV-related hepatocellularcarcinoma
Antonio Bertoletti, Maurizia Brunetto, Mala K Maini, Ferruccio Bonino, Waseem Qasim & Hans Stauss
Article: e1008354
Published online: 22 May 2015
AbstractforT cell receptor-therapy in HBV-related hepatocellularcarcinoma | Full Text | References | PDF (158.3 KB)
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Original Research

Assessing a novel immuno-oncology-based combination therapy: Ipilimumab plus electrochemotherapy
Nicola Mozzillo, Ester Simeone, Lucia Benedetto, Marcello Curvietto, Diana Giannarelli, Giusy Gentilcore, Rosa Camerlingo, Mariaelena Capone, Gabriele Madonna, Lucia Festino, Corrado Caracò, Gianluca Di Monta, Ugo Marone, Massimiliano Di Marzo, Antonio M Grimaldi, Stefano Mori, Gennaro Ciliberto & Paolo A Ascierto
Article: e1008842
Published online: 22 May 2015
AbstractforAssessing a novel immuno-oncology-based combination therapy: Ipilimumab plus electrochemotherapy | Full Text | References | PDF (451.4 KB)
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Cervical (pre)neoplastic microenvironment promotes the emergence of tolerogenic dendritic cells via RANKL secretion
Stéphanie A Demoulin, Joan Somja, Anaëlle Duray, Samuel Guénin, Patrick Roncarati, Philippe O Delvenne, Michael F Herfs & Pascale M Hubert
Article: e1008334
Published online: 22 May 2015
AbstractforCervical (pre)neoplastic microenvironment promotes the emergence of tolerogenic dendritic cells via RANKL secretion | Full Text | References | PDF (1.1 MB) | Supplemental
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Interferon-γ-induced activation of JAK1 and JAK2 suppresses tumor cell susceptibility to NK cells through upregulation of PD-L1 expression
Roberto Bellucci, Allison Martin, Davide Bommarito, Kathy Wang, Steen H Hansen, Gordon J Freeman & Jerome Ritz
Article: e1008824
Published online: 22 May 2015
AbstractforInterferon-γ-induced activation of JAK1 and JAK2 suppresses tumor cell susceptibility to NK cells through upregulation of PD-L1 expression | Full Text | References | PDF (922.6 KB) | Supplemental
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Accumulation of tolerogenic human 6-sulfo LacNAc dendritic cells in renal cell carcinoma is associated with poor prognosis
Marieta Toma, Rebekka Wehner, Anja Kloß, Linda Hübner, Georgia Fodelianaki, Kati Erdmann, Susanne Füssel, Stefan Zastrow, Matthias Meinhardt, Barbara Seliger, Dorothee Brech, Elfriede Noessner, Torsten Tonn, Knut Schäkel, Martin Bornhäuser, Michael P Bachmann, Manfred P Wirth, Gustavo Baretton & Marc Schmitz
Article: e1008342
Published online: 22 May 2015
AbstractforAccumulation of tolerogenic human 6-sulfo LacNAc dendritic cells in renal cell carcinoma is associated with poor prognosis | Full Text | References | PDF (1 MB) | Supplemental
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Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors
Alexander Pedroza-Gonzalez, Guoying Zhou, Ernesto Vargas-Mendez, Patrick PC Boor, Shanta Mancham, Cornelis Verhoef, Wojciech G Polak, Dirk Grünhagen, Qiuwei Pan, Harry LA Janssen, Gina S Garcia-Romo, Katharina Biermann, Eric TTL Tjwa, Jan NM IJzermans, Jaap Kwekkeboom & Dave Sprengers
Article: e1008355
Published online: 22 May 2015
AbstractforTumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors | Full Text | References | PDF (889.8 KB) | Supplemental
  • 1962 Views
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Modifications of the mouse bone marrow microenvironment favor angiogenesis and correlate with disease progression from asymptomatic to symptomatic multiple myeloma
Arianna Calcinotto, Maurilio Ponzoni, Roberto Ria, Matteo Grioni, Elena Cattaneo, Isabella Villa, Maria Teresa Sabrina Bertilaccio, Marta Chesi, Alessandro Rubinacci, Giovanni Tonon, P Leif Bergsagel, Angelo Vacca & Matteo Bellone
Article: e1008850
Published online: 22 May 2015
AbstractforModifications of the mouse bone marrow microenvironment favor angiogenesis and correlate with disease progression from asymptomatic to symptomatic multiple myeloma | Full Text | References | PDF (812.2 KB)
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Open Access
The tumoral and stromal immune microenvironment in malignant pleural mesothelioma: A comprehensive analysis reveals prognostic immune markers
Hideki Ujiie, Kyuichi Kadota, Jun-ichi Nitadori, Joachim G Aerts, Kaitlin M Woo, Camelia S Sima, William D Travis, David R Jones, Lee M Krug & Prasad S Adusumilli
Article: e1009285
Published online: 22 May 2015
AbstractforThe tumoral and stromal immune microenvironment in malignant pleural mesothelioma: A comprehensive analysis reveals prognostic immune markers | Full Text | References | PDF (412 KB) | Supplemental
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Clinical relevance of miR-mediated HLA-G regulation and the associated immune cell infiltration in renal cell carcinoma
Simon Jasinski-Bergner, Christine Stoehr, Juergen Bukur, Chiara Massa, Juliane Braun, Stefan Hüttelmaier, Verena Spath, Roland Wartenberg, Wolfgang Legal, Helge Taubert, Sven Wach, Bernd Wullich, Arndt Hartmann & Barbara Seliger
Article: e1008805
Published online: 22 May 2015
AbstractforClinical relevance of miR-mediated HLA-G regulation and the associated immune cell infiltration in renal cell carcinoma | Full Text | References | PDF (953 KB) | Supplemental
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Tumor infiltrating CD8+ T lymphocyte count is independent of tumor TLR9 status in treatment naïve triple negative breast cancer and renal cell carcinoma
Mikko Mella, Joonas H Kauppila, Peeter Karihtala, Petri Lehenkari, Arja Jukkola-Vuorinen, Ylermi Soini, Päivi Auvinen, Markku H Vaarala, Hanna Ronkainen, Saila Kauppila, Kirsi-Maria Haapasaari, Katri S Vuopala & Katri S Selander
Article: e1002726
Published online: 22 May 2015
AbstractforTumor infiltrating CD8+ T lymphocyte count is independent of tumor TLR9 status in treatment naïve triple negative breast cancer and renal cell carcinoma | Full Text | References | PDF (945.7 KB)
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Exosomes isolated from plasma of glioma patients enrolled in a vaccination trial reflect antitumor immune activity and might predict survival
Laurent Muller, Sylvia Muller-Haegele, Masato Mitsuhashi, William Gooding, Hideho Okada & Theresa L Whiteside
Article: e1008347
Published online: 22 May 2015
AbstractforExosomes isolated from plasma of glioma patients enrolled in a vaccination trial reflect antitumor immune activity and might predict survival | Full Text | References | PDF (433.1 KB) | Supplemental
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Review

Are BiTEs the “missing link” in cancer therapy?
Carter M Suryadevara, Patrick C Gedeon, Luis Sanchez-Perez, Terence Verla, Christopher Alvarez-Breckenridge, Bryan D Choi, Peter E Fecci & John H Sampson
Article: e1008339
Published online: 22 May 2015
AbstractforAre BiTEs the “missing link” in cancer therapy? | Full Text | References | PDF (345.8 KB)
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Understanding high endothelial venules: Lessons for cancer immunology
Ann Ager & Michael J May
Article: e1008791
Published online: 22 May 2015
AbstractforUnderstanding high endothelial venules: Lessons for cancer immunology | Full Text | References | PDF (1.1 MB)
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