980
Views
677
CrossRef citations to date
0
Altmetric
Research Article

The Human Hepatic Cytochromes P450 Involved in Drug Metabolism

&
Pages 1-21 | Published online: 25 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (77)

Zhuoling An, Yuan Sun, Chen Shi & Lihong Liu. (2023) Metabonomic and transcriptomic analyses of Tripterygium glycosides tablet-induced hepatotoxicity in rats. Drug and Chemical Toxicology 46:4, pages 650-664.
Read now
Sm Faysal Bellah, Md. Abdus Salam, S. M. Saker Billah & Md Rezaul Karim. (2023) Genetic association in CYP3A4 and CYP3A5 genes elevate the risk of prostate cancer. Annals of Human Biology 50:1, pages 63-75.
Read now
A. K. Gupta, M. Venkataraman, M. Talukder & M. A. Bamimore. (2022) Finasteride for hair loss: a review. Journal of Dermatological Treatment 33:4, pages 1938-1946.
Read now
Muhammad Waseem, Feiyan Huang, Qiyu Wang, Mehtab Muhammad Aslam, Farhat Abbas, Fiaz Ahmad, Umair Ashraf, Waseem Hassan, Sajid Fiaz, Xianwen Ye, Lei Yu & Yanguo Ke. (2021) Identification, methylation profiling, and expression analysis of stress-responsive cytochrome P450 genes in rice under abiotic and phytohormones stresses. GM Crops & Food 12:1, pages 551-563.
Read now
Guiying Zhang, Yanping Zhang, Xianjie Ma, Xin Yang, Yuyan Cai & Wenli Yin. (2021) Pogostone inhibits the activity of CYP3A4, 2C9, and 2E1 in vitro. Pharmaceutical Biology 59:1, pages 530-534.
Read now
Meng Li, Xiaoyan Liu, Yuzhen Wang & Xiuli Ju. (2020) In vitro effects of peimine on the activity of cytochrome P450 enzymes. Xenobiotica 50:10, pages 1202-1207.
Read now
Iram Kaukab, Syed Nisar Hussain Shah, Zelal Jaber Kharaba, Manal Ali Buabeid, Yaseen Abd Alfoteih & Ghulam Murtaza. (2020) Effect of clarithromycin pre-treatment on the pharmacokinetics of metoclopramide after their simultaneous oral intake. Expert Opinion on Drug Metabolism & Toxicology 16:8, pages 735-740.
Read now
Jinxiu Li, Haibin Wen & Zhiqiang Gao. (2020) In vitro inhibitory effects of phellodendrine on human liver cytochrome P450 enzymes. Xenobiotica 50:2, pages 154-159.
Read now
Yang Li, Jing Qin, Hong Wu, Yongmei Xu, Li Zhang, Keren Su, Ying Cui & Haiping Wang. (2020) In vitro inhibitory effect of lysionotin on the activity of cytochrome P450 enzymes. Pharmaceutical Biology 58:1, pages 695-700.
Read now
Xunge Zhang, Ping Feng, Xinfu Gao, Bin Wang, Chunxia Gou & Ruimin Bian. (2020) In vitro inhibitory effects of cepharanthine on human liver cytochrome P450 enzymes. Pharmaceutical Biology 58:1, pages 247-252.
Read now
Lu Liu, Xiangang Cao, Tingxin Li & Xiaohua Li. (2019) Effects of catalpol on the activity of human liver cytochrome P450 enzymes. Xenobiotica 49:11, pages 1289-1295.
Read now
Jingwei Zhang, Chuansheng Li, Jingfa Zhang & Fan Zhang. (2019) In vitro inhibitory effects of sophocarpine on human liver cytochrome P450 enzymes. Xenobiotica 49:10, pages 1127-1132.
Read now
Qingling Zhao, Jinlan Wei & Hongying Zhang. (2019) Effects of quercetin on the pharmacokinetics of losartan and its metabolite EXP3174 in rats. Xenobiotica 49:5, pages 563-568.
Read now
Ning Zhang, Jing Liu, Zhixia Chen & Wenwen Dou. (2019) In vitro inhibitory effects of kaempferitrin on human liver cytochrome P450 enzymes. Pharmaceutical Biology 57:1, pages 571-576.
Read now
Xiaoyi Hao, Jianlei Yuan, Yansen Xu, Zhao Wang, Jianzhang Hou & Tao Hu. (2018) In vitro inhibitory effects of pristimerin on human liver cytochrome P450 enzymes. Xenobiotica 48:12, pages 1185-1191.
Read now
Gang Dong, Yun Zhou & Xiaoli Song. (2018) In vitro inhibitory effects of bergenin on human liver cytochrome P450 enzymes. Pharmaceutical Biology 56:1, pages 620-625.
Read now
Jinlan Wei, Hongying Zhang & Qingling Zhao. (2018) In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes. Pharmaceutical Biology 56:1, pages 363-367.
Read now
Baiping Dong, Suowei Yuan, Jinsheng Hu & Yanzhen Yan. (2018) Effects of Ginkgo leaf tablets on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism. Pharmaceutical Biology 56:1, pages 333-336.
Read now
Jixiao Lang, Wei Li, Jingming Zhao, Kaiyou Wang & Dexi Chen. (2017) Inhibitory effects of curculigoside on human liver cytochrome P450 enzymes. Xenobiotica 47:10, pages 849-855.
Read now
Lu Liu, Sen Sun, Hongbing Rui & Xiaohua Li. (2017) In vitro inhibitory effects of dihydromyricetin on human liver cytochrome P450 enzymes. Pharmaceutical Biology 55:1, pages 1868-1874.
Read now
Hong Li, Lu Liu, Lei Xie, Dongmei Gan & Xiaoqing Jiang. (2016) Effects of berberine on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism. Pharmaceutical Biology 54:12, pages 2886-2894.
Read now
Jin H. Yoon, Scott D. Lane & Michael F. Weaver. (2015) Opioid Analgesics and Nicotine: More Than Blowing Smoke. Journal of Pain & Palliative Care Pharmacotherapy 29:3, pages 281-289.
Read now
Chin Eng Ong, Yan Pan, Joon Wah Mak & Rusli Ismail. (2013) In vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability. Expert Opinion on Drug Metabolism & Toxicology 9:9, pages 1097-1113.
Read now
Abidemi J. Akindele, Erika A. Eksioglu, Jason C. Kwan, Olufunmilayo O. Adeyemi, Chen Liu, Hendrik Luesch & Margaret O. James. (2011) Biological effects of Byrsocarpus coccineus in vitro. Pharmaceutical Biology 49:2, pages 152-160.
Read now
Toshihiro Mitaka & Hidekazu Ooe. (2010) Characterization of hepatic-organoid cultures. Drug Metabolism Reviews 42:3, pages 472-481.
Read now
Minoli A Perera. (2010) The missing linkage: what pharmacogenetic associations are left to find in CYP3A?. Expert Opinion on Drug Metabolism & Toxicology 6:1, pages 17-28.
Read now
Melissa A Kramer & Timothy S Tracy. (2008) Studying cytochrome P450 kinetics in drug metabolism. Expert Opinion on Drug Metabolism & Toxicology 4:5, pages 591-603.
Read now
Steven N Hart & Xiao-bo Zhong. (2008) P450 oxidoreductase: genetic polymorphisms and implications for drug metabolism and toxicity. Expert Opinion on Drug Metabolism & Toxicology 4:4, pages 439-452.
Read now
James J Cali, Andrew Niles, Michael P Valley, Martha A O'Brien, Terry L Riss & John Shultz. (2008) Bioluminescent assays for ADMET. Expert Opinion on Drug Metabolism & Toxicology 4:1, pages 103-120.
Read now
Perrine Hoet & Dominique Lison. (2008) Ototoxicity of Toluene and Styrene: State of Current Knowledge. Critical Reviews in Toxicology 38:2, pages 127-170.
Read now
C. Woodland, T. T. Huang, E. Gryz, R. Bendayan & J. P. Fawcett. (2008) Expression, Activity and Regulation of CYP3A in Human and Rodent Brain. Drug Metabolism Reviews 40:1, pages 149-168.
Read now
B. K. Muralidhara & James R. Halpert. (2007) Thermodynamics of Ligand Binding to P450 2B4 and P450eryF Studied by Isothermal Titration Calorimetry. Drug Metabolism Reviews 39:2-3, pages 539-556.
Read now
Gail D Anderson. (2006) Using pharmacokinetics to predict the effects of pregnancy and maternal–infant transfer of drugs during lactation. Expert Opinion on Drug Metabolism & Toxicology 2:6, pages 947-960.
Read now
James J Cali, Dongping Ma, Mary Sobol, Daniel J Simpson, Susan Frackman, Troy D Good, William J Daily & David Liu. (2006) Luminogenic cytochrome P450 assays. Expert Opinion on Drug Metabolism & Toxicology 2:4, pages 629-645.
Read now
M. G. Soars, K. Grime & R. J. Riley. (2006) Comparative analysis of substrate and inhibitor interactions with CYP3A4 and CYP3A5. Xenobiotica 36:4, pages 287-299.
Read now
Charity D Scripture, William D Figg & Alex Sparreboom. (2006) The role of drug-metabolising enzymes in clinical responses to chemotherapy. Expert Opinion on Drug Metabolism & Toxicology 2:1, pages 17-25.
Read now
Russell E. Lewis. (2006) Managing drug interactions in the patient with aspergillosis. Medical Mycology 44:sup1, pages 349-356.
Read now
Shufeng Zhou, Eli Chan, Wei Duan, Min Huang & Yu-Zong Chen. (2005) Drug Bioactivation Covalent Binding to Target Proteins and Toxicity Relevance. Drug Metabolism Reviews 37:1, pages 41-213.
Read now
Aqel W. Abu-Qare & Mohamed B. Abou-Donia. (2001) DEET ( N,N -DIETHYL- m -TOLUAMIDE) ALONE AND IN COMBINATION WITH PERMETHRIN INCREASED URINARY EXCRETION OF 6β-HYDROXYCORTISOL IN RATS, A MARKER OF HEPATIC CYP3A INDUCTION. Journal of Toxicology and Environmental Health, Part A 64:5, pages 373-384.
Read now
STEVEN A. WRIGHTON, ERIN G. SCHUETZ, KENNETH E. THUMMEL, DANNY D. SHEN, KENNETH R. KORZEKWA & PAUL B. WATKINS. (2000) THE HUMAN CYP3A SUBFAMILY: PRACTICAL CONSIDERATIONS*. Drug Metabolism Reviews 32:3-4, pages 339-361.
Read now
V. Meunier, M. Bourrie, B. Julian, E. Marti, F. Guillou, Y. Berger & G. Fabre. (2000) Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up. Xenobiotica 30:6, pages 589-607.
Read now
D. D. Surry, G. Meneses-Lorente, R. Heavens, A. Jack & D. C. Evans. (2000) Rapid determination of rat hepatocyte mRNA induction potential using oligonucleotide probes for CYP1A1, 1A2, 3A and 4A1. Xenobiotica 30:5, pages 441-456.
Read now
J. J. P. Bogaards, M. Bertrand, P. Jackson, M. J. Oudshoorn, R. J. Weaver, P. J. Van Bladeren & B. Walther. (2000) Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man. Xenobiotica 30:12, pages 1131-1152.
Read now
Hye Suk Lee, Hee Yong Lee, Hee Kyoung Gu, Sang Seop Han, Chul-Ho Yun, Jeong Han Kim, Jung-Ae Kim, Eung-Seok Lee, Doo-Hyun Nam & Tae Cheon Jeong. (2000) Effects of flupyrazofos on liver microsomal cytochrome P450 in the male Fischer 344 rat. Xenobiotica 30:12, pages 1123-1130.
Read now
SEAN EKINS & STEVEN A. WRIGHTON. (1999) THE ROLE OF CYP2B6 IN HUMAN XENOBIOTIC METABOLISM*. Drug Metabolism Reviews 31:3, pages 719-754.
Read now
PAULA E. SCARBOROUGH, JIXIANG MA, WEI QU & DARRYL C. ZELDIN. (1999) P450 SUBFAMILY CYP2J AND THEIR ROLE IN THE BIOACTIVATION OF ARACHIDONIC ACID IN EXTRAHEPATIC TISSUES*. Drug Metabolism Reviews 31:1, pages 205-234.
Read now
STEVEN A. WRIGHTON & BARBARA J. RING. (1999) PREDICTING DRUG INTERACTIONS AND PHARMACOKINETIC VARIABILITY WITH IN VITRO METHODS: THE OLANZAPINE EXPERIENCE*. Drug Metabolism Reviews 31:1, pages 15-28.
Read now
Lars W. Wormhoudt, Jan N. M. Commandeur & Nico P. E. Vermeulen. (1999) Genetic Polymorphisms of Human N-Acetyltransferase, Cytochrome P450, Glutathione-S-Transferase, and Epoxide Hydrolase Enzymes: Relevance to Xenobiotic Metabolism and Toxicity. Critical Reviews in Toxicology 29:1, pages 59-124.
Read now
GeorgeJ. Hammons, JoyceV. Fletcher, KristyR. Stepps, ElijahA. Smith, DouglasA. Balentine, MatthewE. Harbowy & FredF. Kadlubar. (1999) Effects of chemoprotective agents on the metabolic activation of the carcinogenic arylamines PhIP and 4‐aminobiphenyl in human and rat liver microsomes. Nutrition and Cancer 33:1, pages 46-52.
Read now
JohnK. Pollak. (1998) A short review of the problems posed by xenobiotics in chemical mixtures and the role of mixed function oxidases. International Journal of Environmental Health Research 8:2, pages 157-163.
Read now
Kristine Fonck, Christel Haenebalcke, Alex Hemeryck, Frans Belpaire, Luc Jordaens, Paul Calle & Walter Buylaert. (1998) ECG Changes and Plasma Concentrations of Propafenone and Its Metabolites in a Case of Severe Poisoning. Journal of Toxicology: Clinical Toxicology 36:3, pages 247-251.
Read now
Cheryl A. Mugford & Gregory L. Kedderis. (1998) Sex-Dependent Metabolism of Xenobiotics. Drug Metabolism Reviews 30:3, pages 441-498.
Read now
Agneta Löf & Gunnar Johanson. (1998) Toxicokinetics of Organic Solvents: A Review of Modifying Factors. Critical Reviews in Toxicology 28:6, pages 571-650.
Read now
Jukka Hakkola, Olavi Pelkonen, Markku Pasanen & Hannu Raunio. (1998) Xenobiotic-Metabolizing Cytochrome P450 Enzymes in the Human Feto-Placental Unit: Role in Intrauterine Toxicity. Critical Reviews in Toxicology 28:1, pages 35-72.
Read now
Chong‐Kuei Lii, Wei‐Che Sung, Yuh‐Jane Ko & Haw‐Wen Chen. (1998) α‐Tocopherol acetate supplementation enhances rat hepatic cytochrome PROD activity in the presence of phenobarbital induction. Nutrition and Cancer 32:1, pages 37-42.
Read now
Haw‐Wen Chen, Chong‐Kuei Lii, Wei‐Che Sung & Yuh‐Jane Ko. (1998) Effect of vitamin e on rat hepatic cytochrome p‐450 activity. Nutrition and Cancer 31:3, pages 178-183.
Read now
O. PELKONEN, J. MÄEENPÄEÄ, P. TAAVITSAINEN, A. RAUTIO & H. RAUNIO. (1998) Inhibition and induction of human cytochrome P450 (CYP) enzymes. Xenobiotica 28:12, pages 1203-1253.
Read now
D. F. V. Lewis, P. G. Brantom, C. Ioannides, R. Walker & D. V. Parke. (1997) Nitrosamine Carcinogenesis: Rodent Assays, Quantitative Structure-Activity Relationships, and Human Risk Assessment. Drug Metabolism Reviews 29:4, pages 1055-1078.
Read now
Haw‐Wen Chen, Chong‐Kuei Lii, Mei‐Hsiang Wu, Chu‐Chin Ou & Lee‐Yan Sheen. (1997) Amount and type of dietary lipid modulate rat hepatic cytochrome P‐450 activity. Nutrition and Cancer 29:2, pages 174-180.
Read now
H. KIM, R. S. WANG, E. ELOVAARA, H. RAUNIO, O. PELKONEN, T. AOYAMA, H. VAINIO & T. NAKAJIMA*. (1997) Cytochrome P450 isozymes responsible for the metabolism of toluene and styrene in human liver microsomes. Xenobiotica 27:7, pages 657-665.
Read now
Peter G. Wells & Louise M. Winn. (1996) Biochemical Toxicology of Chemical Teratogenesis. Critical Reviews in Biochemistry and Molecular Biology 31:1, pages 1-40.
Read now
H. Yamazaki, S. Hiroki, T. Urano, K. Inoue & T. Shimada. (1996) Effects of roxithromycin, erythromycin and troleandomycin on their N-demethylation by rat and human cytochrome P450 enzymes. Xenobiotica 26:11, pages 1143-1153.
Read now
Jeffrey R. Aeschlimann & Linda S. Tyler. (1996) Drug Interactions Associated with Cytochrome P-450 Enzymes. Journal of Pharmaceutical Care in Pain & Symptom Control 4:4, pages 35-54.
Read now
B. L. Blake, R. L. Rose, R. B. Mailman, P. E. Levi & E. Hodgson. (1995) Metabolism of thioridazine by microsomal monooxygenases: relative roles of P450 and flavin-containing monooxygenase. Xenobiotica 25:4, pages 377-393.
Read now
Markku Pasanen & Olavi Pelkonen. (1994) The Expression and Environmental Regulation of P450 Enzymes in Human Placenta. Critical Reviews in Toxicology 24:3, pages 211-229.
Read now
Frank J. Gonzalez & Harry V. Gelboin. (1994) Role of Human Cytochromes P450 in the Metabolic Activation of Chemical Carcinogens and Toxins. Drug Metabolism Reviews 26:1-2, pages 165-183.
Read now
Judy L Raucy, James C. Kraner & Jerome M. Lasker. (1993) Bioactivation of Halogenated Hydrocarbons by Cytochrome P4502E1. Critical Reviews in Toxicology 23:1, pages 1-20.
Read now
C. Ioannides & D. V. Parke. (1993) Induction of Cytochrome P4501 as an Indicator of Potential Chemical Carcinogenesis. Drug Metabolism Reviews 25:4, pages 485-501.
Read now
Steven A. Wrighton, Mark Vandenbranden, Jeffrey C. Stevens, Lisa A. Shipley, Barbara J. Ring, John R. Cashman & Allan E. Rettie. (1993) In Vitro Methods for Assessing Human Hepatic Drug Metabolism: Their use in Drug Development. Drug Metabolism Reviews 25:4, pages 453-484.
Read now

Articles from other publishers (600)

Antoine Baldacci, Emeric Saguin, Alexander Balcerac, Stéphane Mouchabac, Florian Ferreri, Raphael Gaillard, Marie-Dominique Colas, Hervé Delacour & Alexis Bourla. (2023) Pharmacogenetic Guidelines for Psychotropic Drugs: Optimizing Prescriptions in Clinical Practice. Pharmaceutics 15:11, pages 2540.
Crossref
Dibyendu Mondal, Harrison M. Snodgrass, Christian A. Gomez & Jared C. Lewis. (2023) Non-Native Site-Selective Enzyme Catalysis. Chemical Reviews 123:16, pages 10381-10431.
Crossref
Robert S. Foti. (2023) Cytochrome P450 and Other Drug-Metabolizing Enzymes As Therapeutic Targets. Drug Metabolism and Disposition 51:8, pages 936-949.
Crossref
E. Thépaut, C. Brochot, K. Chardon, S. Personne & F.A. Zeman. (2023) Pregnancy-PBPK models: How are biochemical and physiological processes integrated?. Computational Toxicology 27, pages 100282.
Crossref
Mingao Zhou, Yifei Jiang, Xuhui Liu, Weilong Kong, Chenhao Zhang, Jian Yang, Simin Ke & Yangsheng Li. (2023) Genome-Wide Identification and Evolution Analysis of the CYP76 Subfamily in Rice (Oryza sativa). International Journal of Molecular Sciences 24:10, pages 8522.
Crossref
Jiayin Hu, Tingting Hu, Zhe Guo, Yonggui Song, Lina Shan & Xianbao Shi. (2022) Species Difference in the Metabolism of Mulberrin <i>in Vitro</i> and Its Inhibitory Effect on Cytochrome P450 and UDP-Glucuronosyltransferase Enzymes. Chemical and Pharmaceutical Bulletin 70:10, pages 669-678.
Crossref
Ahizechukwu C. Eke. (2022) An update on the physiologic changes during pregnancy and their impact on drug pharmacokinetics and pharmacogenomics. Journal of Basic and Clinical Physiology and Pharmacology 33:5, pages 581-598.
Crossref
Wenjie ChenGenpeng LiKe JiangJinen SongRunzi DuHui YangJuxiang GouZhihui LiJingqiang ZhuJianyong Lei. (2022) Dexamethasone for Postoperative Nausea and Vomiting in Papillary Thyroid Carcinoma Patients: A Randomized Clinical Trial. Journal of the American College of Surgeons 235:3, pages 454-467.
Crossref
Menglu Li, Yasunori Nawa, Seiichi Ishida, Yasunari Kanda, Satoshi Fujita & Katsumasa Fujita. (2022) Label-free chemical imaging of cytochrome P450 activity by Raman microscopy. Communications Biology 5:1.
Crossref
A. Baldacci, E. Saguin, S. Annette, B. Lahutte, M.-D. Colas & H. Delacour. (2022) Pharmacogénétique des cytochromes appliquée à la prescription des antidépresseurs : mode d’emploi. L'Encéphale 48:4, pages 462-471.
Crossref
Shanmin Zheng, Jiawei Guo, Fangyuan Cheng, Zhengquan Gao, Lei Du, Chunxiao Meng, Shengying Li & Xingwang Zhang. (2022) Cytochrome P450s in algae: Bioactive natural product biosynthesis and light-driven bioproduction. Acta Pharmaceutica Sinica B 12:6, pages 2832-2844.
Crossref
Jun Lu, Hong-Yan Ren, Jun-Shik Choi, Cheng Li & Jian-Peng Guo. (2022) Effects of Aspirin on the Bioavailability and Pharmacokinetics of Repaglinide: Possible Role of Cytochrome P450 3A Isoforms Inhibition by Aspirin. Pharmaceutical Chemistry Journal 55:11, pages 1151-1156.
Crossref
Sadegh Seidi, Aziz Eftekhari, Ameer Khusro, Reza Shiri Heris, Muhammad Umar Khayam Sahibzada & Márió Gajdács. (2022) Simulation and modeling of physiological processes of vital organs in organ-on-a-chip biosystem. Journal of King Saud University - Science 34:1, pages 101710.
Crossref
Amjad Khan, Umm-e-Kalsoom, Asad Khan, Abdul Wahid, Saima Mushtaq, Yusra Habib Khan, Faheem Maqbool, Faiz Ullah Khan, Tauqeer Hussain Mallhi & Gul Majid Khan. 2022. Biochemistry of Drug Metabolizing Enzymes. Biochemistry of Drug Metabolizing Enzymes 209 230 .
Yasra Sayyed, Kanwal Rehman, Muhammad Sajid Hamid Akash, Sairah Hafeez Kamran & Mohammad Badran. 2022. Biochemistry of Drug Metabolizing Enzymes. Biochemistry of Drug Metabolizing Enzymes 305 321 .
Martin Jugenburg & Waqqas Jalil. 2022. Manual of Cosmetic Surgery and Medicine. Manual of Cosmetic Surgery and Medicine 49 71 .
Shweta Dutta, Saraswati Prasad Mishra, Anil Kumar Sahu, Koushlesh Mishra, Pankaj Kashyap & Bhavna Sahu. 2021. Drug Metabolism. Drug Metabolism.
Ling Ye, Zeying Feng, Longjian Huang, Chengjun Guo, Xiong Wu, Li He, Wei Tan, Yi Wang, Xuehong Wu, Biwen Hu, Tong Li, Guoping Yang, Guo Chengxian & Qingnan He. (2021) Causality Evaluation of Drug-Induced Liver Injury in Newborns and Children in the Intensive Care Unit Using the Updated Roussel Uclaf Causality Assessment Method. Frontiers in Pharmacology 12.
Crossref
Shalini Roy Chowdhury, Oindrilla Dutta Gupta, Arnab Kumar Ghosh, Partha Sarathi Singha, Syed Benazir Firdaus & Klaus Klarskov. (2021) Genetic variations and epigenetic modulations in CYP genes: Implications in NSAID-treatment of arthritis patients. The Nucleus 64:3, pages 331-342.
Crossref
Mu-Zi Li, Yi Zhao, Hao-Ran Wang, Milton Talukder & Jin-Long Li. (2021) Lycopene Preventing DEHP-Induced Renal Cell Damage Is Targeted by Aryl Hydrocarbon Receptor. Journal of Agricultural and Food Chemistry 69:43, pages 12853-12861.
Crossref
Albert P. Li. 2021. Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity. Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity 79 137 .
Nicole Moschny, Gudrun Hefner, Renate Grohmann, Gabriel Eckermann, Hannah B Maier, Johanna Seifert, Johannes Heck, Flverly Francis, Stefan Bleich, Sermin Toto & Catharina Meissner. (2021) Therapeutic Drug Monitoring of Second- and Third-Generation Antipsychotic Drugs—Influence of Smoking Behavior and Inflammation on Pharmacokinetics. Pharmaceuticals 14:6, pages 514.
Crossref
Hafiz Ishfaq Ahmad, Gulnaz Afzal, Adil Jamal, Shumaila Kiran, Musarrat Abbas Khan, Khalid Mehmood, Zahid Kamran, Irfan Ahmed, Shakeel Ahmad, Asmar Ahmad, Javed Hussain & Sadaf Almas. (2021) In Silico Structural, Functional, and Phylogenetic Analysis of Cytochrome (CYPD) Protein Family. BioMed Research International 2021, pages 1-13.
Crossref
M. Saeed Mirzaei, Maxim V. Ivanov, Avat Arman Taherpour & Saber Mirzaei. (2021) Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Computational Insights. Chemical Research in Toxicology 34:4, pages 959-987.
Crossref
Chun‐Chi Chen, Jian Min, Lilan Zhang, Yu Yang, Xuejing Yu & Rey‐Ting Guo. (2020) Advanced Understanding of the Electron Transfer Pathway of Cytochrome P450s. ChemBioChem 22:8, pages 1317-1328.
Crossref
Zhang-Xu He, Tao-Qian Zhao, Yun-Peng Gong, Xin Zhang, Li-Ying Ma & Hong-Min Liu. (2020) Pyrimidine: A promising scaffold for optimization to develop the inhibitors of ABC transporters. European Journal of Medicinal Chemistry 200, pages 112458.
Crossref
Benjamin Berger, Priska Kaufmann, Annelize Koch & Jasper Dingemanse. (2020) Impact of the Selective Orexin‐1 Receptor Antagonist ACT‐539313 on the Pharmacokinetics of the CYP3A Probe Drug Midazolam in Healthy Male Subjects. The Journal of Clinical Pharmacology 60:7, pages 931-941.
Crossref
Cole Tolledo, Marlaina R. Stocco, Sharon Miksys, Frank J. Gonzalez & Rachel F. Tyndale. (2020) Human CYP2D6 Is Functional in Brain In Vivo: Evidence from Humanized CYP2D6 Transgenic Mice. Molecular Neurobiology 57:6, pages 2509-2520.
Crossref
Laith N. AL-Eitan. (2020) Pharmacogenomic landscape of VIP genetic variants in Jordanian Arabs and comparison with worldwide populations. Gene 737, pages 144408.
Crossref
Fumiya Tao, Kanae Sayo, Kazuyuki Sugimoto, Shigehisa Aoki & Nobuhiko Kojima. (2020) Development of a tunable method to generate various three-dimensional microstructures by replenishing macromolecules such as extracellular matrix components and polysaccharides. Scientific Reports 10:1.
Crossref
Hannah K. Betcher & Alfred L. GeorgeJr.Jr.. (2020) Pharmacogenomics in pregnancy. Seminars in Perinatology 44:3, pages 151222.
Crossref
Michael Murray, Ariane Roseblade, Yongjuan Chen, Kirsi Bourget & Tristan Rawling. (2020) Carbon Chain Length Modulates MDA‐MB‐231 Breast Cancer Cell Killing Mechanisms by Mitochondrially Targeted Aryl−Urea Fatty Acids. ChemMedChem 15:2, pages 247-255.
Crossref
Marcelo Allevato & Juliana Bancovsky. 2020. Women's Mental Health. Women's Mental Health 227 239 .
Katarzyna Litwińska, Felix Bischoff, Falko Matthes, Rüdiger Bode, Twan Rutten & Gotthard Kunze. (2019) Characterization of recombinant laccase from Trametes versicolor synthesized by Arxula adeninivorans and its application in the degradation of pharmaceuticals. AMB Express 9:1.
Crossref
Jennifer E. Bissada, Vivian Truong, Arsany A. Abouda, Kahari J. Wines, Rachel D. Crouch & Klarissa D. Jackson. (2019) Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation. Drug Metabolism and Disposition 47:11, pages 1257-1269.
Crossref
Nicolas Hohmann, Antje Blank, Jürgen Burhenne, Yosuke Suzuki, Gerd Mikus & Walter E. Haefeli. (2019) Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses. British Journal of Clinical Pharmacology 85:10, pages 2310-2320.
Crossref
Merel van Nuland, Hilde Rosing, Alwin D. R. Huitema & Jos H. Beijnen. (2019) Predictive Value of Microdose Pharmacokinetics. Clinical Pharmacokinetics 58:10, pages 1221-1236.
Crossref
Xin Li, Ye Tian, Mei-Juan Tu, Pui Yan Ho, Neelu Batra & Ai-Ming Yu. (2019) Bioengineered miR-27b-3p and miR-328-3p modulate drug metabolism and disposition via the regulation of target ADME gene expression. Acta Pharmaceutica Sinica B 9:3, pages 639-647.
Crossref
Hajar G. Ghalehshahi, Saeed Balalaie, Hamid R. Sohbati, Homa Azizian & Mohammad S. Alavijeh. (2019) Synthesis, CYP 450 evaluation, and docking simulation of novel 4‐aminopyridine and coumarin derivatives. Archiv der Pharmazie 352:3.
Crossref
Zhao Chen, Yanfeng Cao, Yanling Zhang & Yanjiang Qiao. (2019) A Novel Discovery: Holistic Efficacy at the Special Organ Level of Pungent Flavored Compounds from Pungent Traditional Chinese Medicine. International Journal of Molecular Sciences 20:3, pages 752.
Crossref
Kang Xiao, Jie Gao, Shi-Jia Weng, Yan Fang, Na Gao, Qiang Wen, Han Jin & Hai-Ling Qiao. (2018) CYP3A4/5 Activity Probed with Testosterone and Midazolam: Correlation between Two Substrates at the Microsomal and Enzyme Levels. Molecular Pharmaceutics 16:1, pages 382-392.
Crossref
Bernardino M Mendez, Jayne E Coleman & Jeffrey M Kenkel. (2019) Optimizing Patient Outcomes and Safety With Liposuction. Aesthetic Surgery Journal 39:1, pages 66-82.
Crossref
Hadi Molanaei, Abdul Rashid Qureshi, Olof Heimbürger, Bengt Lindholm, Ulf Diczfalusy, Björn Anderstam, Leif Bertilsson & Peter Stenvinkel. (2018) Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients. BMC Pharmacology and Toxicology 19:1.
Crossref
Violetta Mohos, Tímea Bencsik, Gabriella Boda, Eszter Fliszár-Nyúl, Beáta Lemli, Sándor Kunsági-Máté & Miklós Poór. (2018) Interactions of casticin, ipriflavone, and resveratrol with serum albumin and their inhibitory effects on CYP2C9 and CYP3A4 enzymes. Biomedicine & Pharmacotherapy 107, pages 777-784.
Crossref
Xiuxuan Zhang, Yan Zhou, Xiaofei Gu, Yu Cheng, Manxin Hong, Liqiang Yan, Fulong Ma & Zhengjian Qi. (2018) Synthesis of a selective ratiometric fluorescent probe based on Naphthalimide and its application in human cytochrome P450 1A. Talanta 186, pages 413-420.
Crossref
Jia Yin Soo, Michael D. Wiese, Mary J. Berry, I. Caroline McMillen & Janna L. Morrison. (2018) Intrauterine growth restriction may reduce hepatic drug metabolism in the early neonatal period. Pharmacological Research 134, pages 68-78.
Crossref
Nooshin Koolaji, Tristan Rawling, Kirsi Bourget & Michael Murray. (2018) Carboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell Death. ChemMedChem 13:10, pages 1036-1043.
Crossref
Jee-Hyun Jung, Young-Sun Moon, Bo-Mi Kim, Young-Mi Lee, Moonkoo Kim & Jae-Sung Rhee. (2018) Comparative analysis of distinctive transcriptome profiles with biochemical evidence in bisphenol S- and benzo[a]pyrene-exposed liver tissues of the olive flounder Paralichthys olivaceus. PLOS ONE 13:5, pages e0196425.
Crossref
Mohd Yusmaidie Aziz, Kurt-Jürgen Hoffmann & Michael Ashton. (2018) Inhibition of CYP3A by Antimalarial Piperaquine and Its Metabolites in Human Liver Microsomes With IVIV Extrapolation. Journal of Pharmaceutical Sciences 107:5, pages 1461-1467.
Crossref
Jia Yin Soo, Michael D. Wiese, Mary J. Berry & Janna L. Morrison. (2018) Does poor fetal growth influence the extent of fetal exposure to maternal medications?. Pharmacological Research 130, pages 74-84.
Crossref
Chun Zhang, Ai-Min Ren, Jing-Fu Guo, Dan Wang & Li-Ying Yu. (2018) Theoretical design and investigation of 1,8-naphthalimide-based two-photon fluorescent probes for detecting cytochrome P450 1A with separated fluorescence signal. Physical Chemistry Chemical Physics 20:19, pages 13290-13305.
Crossref
Benjamin Stenger, Adrian Gerber, Rita Bernhardt & Frank Hannemann. (2018) Functionalized poly(3-hydroxybutyric acid) bodies as new in vitro biocatalysts. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1866:1, pages 52-59.
Crossref
Ajit Sadana, Neeti Sadana & Richa Sadana. 2018. A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces. A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces 267 292 .
G.L. Kedderis. 2018. Comprehensive Toxicology. Comprehensive Toxicology 128 142 .
E. S. Oh, C. Choi, C. O. Kim, K. H. Kim, Y. N. Kim, S. J. Kim & M. S. Park. (2017) Effects of clarithromycin on the pharmacokinetics of evogliptin in healthy volunteers. Journal of Clinical Pharmacy and Therapeutics 42:6, pages 689-694.
Crossref
Snehasis Jana & Himanshu Rastogi. (2017) Effects of Caffeic Acid and Quercetin on In Vitro Permeability, Metabolism and In Vivo Pharmacokinetics of Melatonin in Rats: Potential for Herb-Drug Interaction. European Journal of Drug Metabolism and Pharmacokinetics 42:5, pages 781-791.
Crossref
Wei Qi, Longlong Tian, Wenzhen An, Qiang Wu, Jianli Liu, Can Jiang, Jun Yang, Bing Tang, Yafeng Zhang, Kangjun Xie, Xinling Wang, Zhan Li & Wangsuo Wu. (2017) Curing the Toxicity of Multi-Walled Carbon Nanotubes through Native Small-molecule Drugs. Scientific Reports 7:1.
Crossref
Shotaro Uehara, Yasuhiro Uno, Kazuyuki Nakanishi, Sakura Ishii, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2017) Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone. Drug Metabolism and Disposition 45:5, pages 457-467.
Crossref
Hanhua Zhang, Guangkui Ya & Hongbing Rui. (2016) Inhibitory Effects of Triptolide on Human Liver Cytochrome P450 Enzymes and P-Glycoprotein. European Journal of Drug Metabolism and Pharmacokinetics 42:1, pages 89-98.
Crossref
Christopher T. Chia, Ryan M. Neinstein & Spero J. Theodorou. (2017) Evidence-Based Medicine: Liposuction. Plastic & Reconstructive Surgery 139:1, pages 267e-274e.
Crossref
Rommel G. Tirona & Richard B. Kim. 2017. Clinical and Translational Science. Clinical and Translational Science 365 388 .
Ceib Phillips & Caitlin Magraw. 2016. Orthognathic Surgery. Orthognathic Surgery 378 388 .
Giovanni Ugolini, Daniela Cruz-Moreira, Roberta Visone, Alberto Redaelli & Marco Rasponi. (2016) Microfabricated Physiological Models for In Vitro Drug Screening Applications. Micromachines 7:12, pages 233.
Crossref
Yan Wang, Myung Hee Kim, Hitomi Shirahama, Jae Ho Lee, Soon Seng Ng, Jeffrey S. Glenn & Nam-Joon Cho. (2016) ECM proteins in a microporous scaffold influence hepatocyte morphology, function, and gene expression. Scientific Reports 6:1.
Crossref
Rong Wang, Hai Zhang, Sen Sun, Yuanyuan Wang, Yifeng Chai & Yongfang Yuan. (2015) Effect of Ginkgo Leaf Tablets on the Pharmacokinetics of Amlodipine in Rats. European Journal of Drug Metabolism and Pharmacokinetics 41:6, pages 825-833.
Crossref
Wynton D. McClary, John P. Sumida, Michele Scian, Lorela Paço & William M. Atkins. (2016) Membrane Fluidity Modulates Thermal Stability and Ligand Binding of Cytochrome P4503A4 in Lipid Nanodiscs. Biochemistry 55:45, pages 6258-6268.
Crossref
Anubhav Das, Meenakshi Srinivasan, Tarini Shankar Ghosh & Sharmila S. Mande. (2016) Xenobiotic Metabolism and Gut Microbiomes. PLOS ONE 11:10, pages e0163099.
Crossref
Na Gao, Xin Tian, Yan Fang, Jun Zhou, Haifeng Zhang, Qiang Wen, Linjing Jia, Jie Gao, Bao Sun, Jingyao Wei, Yunfei Zhang, Mingzhu Cui & Hailing Qiao. (2016) Gene polymorphisms and contents of cytochrome P450s have only limited effects on metabolic activities in human liver microsomes. European Journal of Pharmaceutical Sciences 92, pages 86-97.
Crossref
Eunyoung Lee, Jong Cheol Shon & Kwang-Hyeon Liu. (2016) Simultaneous evaluation of substrate-dependent CYP3A inhibition using a CYP3A probe substrates cocktail. Biopharmaceutics & Drug Disposition 37:6, pages 366-372.
Crossref
Shu-Hao Liou, Mavish Mahomed, Young-Tae Lee & David B. Goodin. (2016) Effector Roles of Putidaredoxin on Cytochrome P450cam Conformational States. Journal of the American Chemical Society 138:32, pages 10163-10172.
Crossref
Jun Zhou, Qiang Wen, Sai-Fei Li, Yun-Fei Zhang, Na Gao, Xin Tian, Yan Fang, Jie Gao, Ming-Zhu Cui, Xiao-Pei He, Lin-Jing Jia, Han Jin & Hai-Ling Qiao. (2016) Significant change of cytochrome P450s activities in patients with hepatocellular carcinoma. Oncotarget 7:31, pages 50612-50623.
Crossref
Cord J. Andreas, Irena Tomaszewska, Uwe Muenster, Dorina van der Mey, Wolfgang Mueck & Jennifer B. Dressman. (2016) Can dosage form-dependent food effects be predicted using biorelevant dissolution tests? Case example extended release nifedipine. European Journal of Pharmaceutics and Biopharmaceutics 105, pages 193-202.
Crossref
Alexander V. LyubimovStéphane Mouly, Isabel Spriet, Joost Wauters, Pieter Annaert, Christophe Meune & Jean‐François Bergmann. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 48 .
F. Kern, Y. Khatri, M. Litzenburger & R. Bernhardt. (2016) CYP267A1 and CYP267B1 from Sorangium cellulosum So ce56 are Highly Versatile Drug Metabolizers. Drug Metabolism and Disposition 44:4, pages 495-504.
Crossref
Kimiko Tomioka, Keigo Saeki, Kenji Obayashi & Norio Kurumatani. (2016) Risk of Lung Cancer in Workers Exposed to Benzidine and/or Beta-Naphthylamine: A Systematic Review and Meta-Analysis. Journal of Epidemiology 26:9, pages 447-458.
Crossref
Masahiro Hiratsuka. (2016) Genetic Polymorphisms and <i>in Vitro</i> Functional Characterization of CYP2C8, CYP2C9, and CYP2C19 Allelic Variants. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 39:11, pages 1748-1759.
Crossref
Sun Joo Kim, Heung Chan Oh, Youn-Chul Kim, Gil-Saeng Jeong & Sangkyu Lee. (2016) Selective Inhibition of Bakuchicin Isolated from Psoralea corylifolia on CYP1A in Human Liver Microsomes . Evidence-Based Complementary and Alternative Medicine 2016, pages 1-7.
Crossref
Arnout Schepers, Cheri Li, Arnav Chhabra, Benjamin Tschudy Seney & Sangeeta Bhatia. (2016) Engineering a perfusable 3D human liver platform from iPS cells. Lab on a Chip 16:14, pages 2644-2653.
Crossref
Akhilesh K. Gaharwar, Ayyoob Arpanaei, Thomas L. Andresen & Alireza Dolatshahi-Pirouz. (2016) 3D Biomaterial Microarrays for Regenerative Medicine: Current State-of-the-Art, Emerging Directions and Future Trends. Advanced Materials 28:4, pages 771-781.
Crossref
Juefeng Wan, Kaitai Liu, Kaixuan Li, Guichao Li & Zhen Zhang. (2015) Can dosimetric parameters predict acute hematologic toxicity in rectal cancer patients treated with intensity-modulated pelvic radiotherapy?. Radiation Oncology 10:1.
Crossref
Wiriyaporn Sumsakul, Wiratchanee Mahavorasirikul & Kesara Na-Bangchang. (2015) Inhibitory Activities of Thai Medicinal Plants with Promising Activities Against Malaria and Cholangiocarcinoma on Human Cytochrome P450. Phytotherapy Research 29:12, pages 1926-1933.
Crossref
Zi-Ru Dai, Guang-Bo Ge, Lei Feng, Jing Ning, Liang-Hai Hu, Qiang Jin, Dan-Dan Wang, Xia Lv, Tong-Yi Dou, Jing-Nan Cui & Ling Yang. (2015) A Highly Selective Ratiometric Two-Photon Fluorescent Probe for Human Cytochrome P450 1A. Journal of the American Chemical Society 137:45, pages 14488-14495.
Crossref
Wenjun Wang, Qiang Shi, Williams B Mattes, Donna L Mendrick & Xi Yang. (2015) Translating extracellular microRNA into clinical biomarkers for drug-induced toxicity: from high-throughput profiling to validation. Biomarkers in Medicine 9:11, pages 1177-1188.
Crossref
Jonghun Kim, Kee-Pyo Kim, Kyung Tae Lim, Seung Chan Lee, Juyong Yoon, Guangqi Song, Seon In Hwang, Hans R. Schöler, Tobias Cantz & Dong Wook Han. (2015) Generation of integration-free induced hepatocyte-like cells from mouse fibroblasts. Scientific Reports 5:1.
Crossref
Lian Yee Yip & Eric Chun Yong Chan. (2015) Investigation of Host–Gut Microbiota Modulation of Therapeutic Outcome. Drug Metabolism and Disposition 43:10, pages 1619-1631.
Crossref
Giuseppe Lombardi, Enrica Rumiato, Roberta Bertorelle, Daniela Saggioro, Patrizia Farina, Alessandro Della Puppa, Fable Zustovich, Franco Berti, Valeria Sacchetto, Raffaella Marcato, Alberto Amadori & Vittorina Zagonel. (2015) Clinical and Genetic Factors Associated With Severe Hematological Toxicity in Glioblastoma Patients During Radiation Plus Temozolomide Treatment. American Journal of Clinical Oncology 38:5, pages 514-519.
Crossref
Wei He, Jing-Jing Wu, Jing Ning, Jie Hou, Hong Xin, Yu-Qi He, Guang-Bo Ge & Wei Xu. (2015) Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice. Toxicology in Vitro 29:7, pages 1569-1576.
Crossref
Young-Hoon Kim, Young-Ji Bae, Hyung Soo Kim, Hey-Jin Cha, Jae-Suk Yun, Ji-Soon Shin, Won-Keun Seong, Yong-Moon Lee & Kyoung-Moon Han. (2015) Measurement of Human Cytochrome P450 Enzyme Induction Based on Mesalazine and Mosapride Citrate Treatments Using a Luminescent Assay. Biomolecules & Therapeutics 23:5, pages 486-492.
Crossref
Alexander V. LyubimovYuan Chen, Jialin Mao & Adrian J. Fretland. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 26 .
Min Huang, Han-ming Wang, Yu Guo, Jie Ping, Man Chen, Dan Xu & Hui Wang. (2015) Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. Journal of Huazhong University of Science and Technology [Medical Sciences] 35:4, pages 502-507.
Crossref
Chunming Lyu, Wenbin Zhou, Yufeng Zhang, Shen Zhang, Fang Kou, Hai Wei, Ning Zhang & Zhong Zuo. (2015) Identification and characterization of in vitro and in vivo metabolites of steroidal alkaloid veratramine . Biopharmaceutics & Drug Disposition 36:5, pages 308-324.
Crossref
Young-Tae Je, Woo-Cheol Sim, Dong-Gwang Kim, Byung-Hwa Jung, Ho-Sang Shin & Byung-Hoon Lee. (2014) Expression of CYP3A in chronic ethanol-fed mice is mediated by endogenous pregnane X receptor ligands formed by enhanced cholesterol metabolism. Archives of Toxicology 89:4, pages 579-589.
Crossref
Hemantkumar Chavan, Feng Li, Robert Tessman, Kristen Mickey, Kenneth Dorko, Timothy Schmitt, Sean Kumer, Sumedha Gunewardena, Nilesh Gaikwad & Partha Krishnamurthy. (2015) Functional Coupling of ATP-binding Cassette Transporter Abcb6 to Cytochrome P450 Expression and Activity in Liver. Journal of Biological Chemistry 290:12, pages 7871-7886.
Crossref
Jinguang Ruan. (2015) Serum Alanine Transaminase Total Bilirubin Concentrations Predict CYP3A Activity as Measured by Midazolam and 1’-Hydroxylation. Medical Science Monitor 21, pages 396-402.
Crossref
Alice Varghese, Jay Savai, Nancy Pandita & Ram Gaud. (2015) In vitro modulatory effects of Terminalia arjuna , arjunic acid, arjunetin and arjungenin on CYP3A4, CYP2D6 and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports 2, pages 806-816.
Crossref
Jeong-Hyun Kim, Hyun Sub Cheong, Byung Lae Park, Lyoung Hyo Kim, Hee Jung Shin, Han Sung Na, Myeon Woo Chung & Hyoung Doo Shin. (2014) Direct sequencing and comprehensive screening of genetic polymorphisms on CYP2 family genes (CYP2A6, CYP2B6, CYP2C8, and CYP2E1) in five ethnic populations. Archives of Pharmacal Research 38:1, pages 115-128.
Crossref
Anandi N. Sheth, Cecile D. Lahiri & Ighovwerha Ofotokun. 2015. Sex and Gender Differences in Infection and Treatments for Infectious Diseases. Sex and Gender Differences in Infection and Treatments for Infectious Diseases 75 102 .
Robim M. Rodrigues, Joery De Kock, Tatyana Y. Doktorova, Vera Rogiers & Tamara Vanhaecke. 2015. Protocols in In Vitro Hepatocyte Research. Protocols in In Vitro Hepatocyte Research 279 285 .
S. Kauferstein, B. Madea & C. Courts. (2014) Forensische MolekularpathologieMolecular pathology in forensic medicine. Rechtsmedizin 24:6, pages 513-532.
Crossref
Kyoko Naramoto, Masashi Kato & Kenji Ichihara. (2014) Effects of an Ethanol Extract of Brazilian Green Propolis on Human Cytochrome P450 Enzyme Activities in Vitro. Journal of Agricultural and Food Chemistry 62:46, pages 11296-11302.
Crossref
Lana Shaya, Chris Dejong & Joanna Y. Wilson. (2014) Expression patterns of cytochrome P450 3B and 3C genes in model fish species. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 166, pages 115-125.
Crossref
Hye-Mi Lee & Chongsuk Ryou. (2014) Targeting of poly( l -lysine) to organs that propagate prions . Journal of Bioactive and Compatible Polymers 29:5, pages 432-444.
Crossref
Taeho Ahn, Chun-Sik Bae & Chul-Ho Yun. (2014) Affinity purification of recombinant human cytochrome P450s 3A4 and 1A2 using mixed micelle systems. Protein Expression and Purification 101, pages 37-41.
Crossref
Erica C. Larson, Laura B. Hathaway, John G. Lamb, Chris D. Pond, Prem P. Rai, Teatulohi K. Matainaho, Pius Piskaut, Louis R. Barrows & Michael R. Franklin. (2014) Interactions of Papua New Guinea medicinal plant extracts with antiretroviral therapy. Journal of Ethnopharmacology 155:3, pages 1433-1440.
Crossref
Mouna Cheikh Rouhou & Sami Haddad. (2014) Modulation of trichloroethylene in vitro metabolism by different drugs in human. Toxicology in Vitro 28:5, pages 732-741.
Crossref
Cigdem Gelegen, Thomas C. Gent, Valentina Ferretti, Zhe Zhang, Raquel Yustos, Fei Lan, Qianzi Yang, Dorothy W. U. Overington, Alexei L. Vyssotski, Hein A. Lith, William Wisden & Nicholas P. Franks. (2014) Staying awake – a genetic region that hinders α 2 adrenergic receptor agonist‐induced sleep . European Journal of Neuroscience 40:1, pages 2311-2319.
Crossref
E. Paige Stout, Michael Y. Choi, Januario E. Castro & Tadeusz F. Molinski. (2014) Potent Fluorinated Agelastatin Analogues for Chronic Lymphocytic Leukemia: Design, Synthesis, and Pharmacokinetic Studies. Journal of Medicinal Chemistry 57:12, pages 5085-5093.
Crossref
Francesca Vinchi, Giada Ingoglia, Deborah Chiabrando, Sonia Mercurio, Emilia Turco, Lorenzo Silengo, Fiorella Altruda & Emanuela Tolosano. (2014) Heme Exporter FLVCR1a Regulates Heme Synthesis and Degradation and Controls Activity of Cytochromes P450. Gastroenterology 146:5, pages 1325-1338.
Crossref
Clare A. Johnston & Pamela M. Crawford. (2014) Anti-Epileptic Drugs and Hormonal Treatments. Current Treatment Options in Neurology 16:5.
Crossref
Sam H. Au, M. Dean Chamberlain, Shruthi Mahesh, Michael V. Sefton & Aaron R. Wheeler. (2014) Hepatic organoids for microfluidic drug screening. Lab on a Chip 14:17, pages 3290.
Crossref
E.L. Gregoraszczuk, A. Ptak, A. Karpeta, E. Fiedor, A. Wróbel, T. Milewicz & J. Falandysz. (2014) Hexachlorobenzene and pentachlorobenzene accumulation, metabolism and effect on steroid secretion and on CYP11A1 and CYP19 expression in cultured human placental tissue. Reproductive Toxicology 43, pages 102-110.
Crossref
Melissa Barker-Haliski, Graeme J. Sills & H. Steve White. 2014. Issues in Clinical Epileptology: A View from the Bench. Issues in Clinical Epileptology: A View from the Bench 295 308 .
Un-Gi Hwang, Jung-Sik Lee & Ju-Chan Kang. (2013) Reponses of the Hepatic Microsomal Cytochrome P450 Monooxygenase System in Rock Bream Oplegnathus fasciatus Exposed to Tributyltin (TBT). Fisheries and aquatic sciences 16:4, pages 261-265.
Crossref
Hylke de Jonge, Henriette de Loor, Krisitin Verbeke, Yves Vanrenterghem & Dirk RJ Kuypers. (2013) Impact of CYP3A5 genotype on tacrolimus versus midazolam clearance in renal transplant recipients: new insights in CYP3A5-mediated drug metabolism . Pharmacogenomics 14:12, pages 1467-1480.
Crossref
Jin-Seok Choi, In Choi & Dong-Hyun Choi. (2013) Effects of nifedipine on the pharmacokinetics of repaglinide in rats: Possible role of CYP3A4 and P-glycoprotein inhibition by nifedipine. Pharmacological Reports 65:5, pages 1422-1430.
Crossref
Christina M. Powers, Ambuja S. Bale, Andrew D. Kraft, Susan L. Makris, Jordan Trecki, John Cowden, Andrew Hotchkiss & Patricia A. Gillespie. (2013) Developmental Neurotoxicity of Engineered Nanomaterials: Identifying Research Needs to Support Human Health Risk Assessment. Toxicological Sciences 134:2, pages 225-242.
Crossref
Hajime Hirao, Pratanphorn Chuanprasit, Ying Yi Cheong & Xiaoqing Wang. (2013) How Is a Metabolic Intermediate Formed in the Mechanism‐Based Inactivation of Cytochrome P450 by Using 1,1‐Dimethylhydrazine: Hydrogen Abstraction or Nitrogen Oxidation?. Chemistry – A European Journal 19:23, pages 7361-7369.
Crossref
Donatella Marazziti, Stefano Baroni, Michela Picchetti, Armando Piccinni, Marina Carlini, Elena Vatteroni, Valentina Falaschi, Amedeo Lombardi & Liliana Dell'Osso. (2013) Pharmacokinetics and pharmacodinamics of psychotropic drugs: effect of sex. CNS Spectrums 18:3, pages 118-127.
Crossref
Jin Sol LeeHyun Sub CheongLyoung Hyo KimJi On KimDoo Won SeoYoung Hoon KimMyeon Woo ChungSoon Young HanHyoung Doo Shin. (2013) Screening of Genetic Polymorphisms of CYP3A4 and CYP3A5 Genes . The Korean Journal of Physiology & Pharmacology 17:6, pages 479.
Crossref
Maho Okubo, Norie Murayama, Makiko Shimizu, Tsutomu Shimada, F. Peter Guengerich & Hiroshi Yamazaki. (2013) The <i>CYP3A4</i> intron 6 C>T polymorphism (<i>CYP3A4*22</i>) is associated with reduced CYP3A4 protein level and function in human liver microsomes. The Journal of Toxicological Sciences 38:3, pages 349-354.
Crossref
Fahad I. Al‐Jenoobi, Khalid M. Alkharfy, Amal M. Alghamdi, Khawla M. Bagulb, Abdullah M. Al‐Mohizea, Saleh Al‐Muhsen, Rabih Halwani, Mohammad Khalid Parvez & Mohammed S. Al‐Dosari. (2012) CYP2C19 Genetic Polymorphism in Saudi Arabians . Basic & Clinical Pharmacology & Toxicology 112:1, pages 50-54.
Crossref
Angela Dudda & Gert Ulrich Kuerzel. 2013. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays 1053 1094 .
Alexander V. LyubimovRichard J. Dimelow, Paul D. Metcalfe & Simon Thomas. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 55 .

Displaying 200 of 677 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.