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Review Article

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

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Pages 600-604 | Received 06 Feb 2015, Accepted 12 Mar 2015, Published online: 22 Jun 2015

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Crossref
Meng Lu, Feng Lu, Caiyu Liao, Yan Guo, Chuanqing Mao, Yongzhen Lai, Xingyu Chen & Weihui Chen. (2023) High throughput miRNA sequencing and bioinformatics analysis identify the mesenchymal cell proliferation and apoptosis related miRNAs during fetal mice palate development. The Journal of Gene Medicine 25:9.
Crossref
Mauro Torres, Zeynep Betts, Rachel Scholey, Mark Elvin, Svetlana Place, Andrew Hayes & Alan J. Dickson. (2023) Long term culture promotes changes to growth, gene expression, and metabolism in CHO cells that are independent of production stability. Biotechnology and Bioengineering 120:9, pages 2389-2402.
Crossref
Lubna Tariq, Azher Arafah, Nouroz Sehar, Aarif Ali, Andleeb Khan, Iyman Rasool, Shahzada Mudasir Rashid, Sheikh Bilal Ahmad, Saba Beigh, Tanveer Ul Hassan Dar & Muneeb U. Rehman. (2023) Novel insights on perils and promises of miRNA in understanding colon cancer metastasis and progression. Medical Oncology 40:10.
Crossref
Jing Luo, Yijue Deng, Yi Ding, Chenguang Tang & Mengqing Wang. (2023) Xiebai Zengye decoction improves respiratory function and attenuates inflammation in juvenile rats with postinfection cough via regulating ERK signaling pathway. Cell Biochemistry and Function.
Crossref
Chi-Chiu Lee, Chia-Jui Yu, Sushree Shankar Panda, Kai-Chi Chen, Kang-Hao Liang, Wan-Chen Huang, Yu-Shiuan Wang, Pei-Chin Ho & Han-Chung Wu. (2023) Epithelial cell adhesion molecule (EpCAM) regulates HGFR signaling to promote colon cancer progression and metastasis. Journal of Translational Medicine 21:1.
Crossref
Xiaocong Chen, Yang An, Mengsi Tan, Dongrui Xie, Ling Liu & Benjin Xu. (2023) Biological functions and research progress of eIF4E. Frontiers in Oncology 13.
Crossref
Minglei Bi, Danyi Li & Jin Zhang. (2023) Research progress and insights on the role of ferroptosis in wound healing. International Wound Journal 20:6, pages 2473-2481.
Crossref
Wei-Feng Cai, Song-Xia Lin, Pan-Yu Ma & Chun-Yan Shen. (2023) Semen Pruni oil attenuates loperamide-induced constipation in mice by regulating neurotransmitters, oxidative stress and inflammatory response. Journal of Functional Foods 107, pages 105676.
Crossref
Isma Gul, Muhammad Nadeem Abbas, Saima Kausar, Jili Luo, Xinyue Gao, Yuhang Mu, Wenhui Fan & Honghuan Cui. (2023) Insight into crustacean cathepsins: Structure-evolutionary relationships and functional roles in physiological processes. Fish & Shellfish Immunology 139, pages 108852.
Crossref
Qun-li Ren, Qian Wang, Xin-qun Zhang, Miao Wang, Huan Hu, Jun-jie Tang, Xiong-tong Yang, Ying-hui Ran, Huan-huan Liu, Zhi-xing Song, Jian-guo Liu & Xiao-lan Li. (2023) Anticancer Activity of Diosgenin and Its Molecular Mechanism. Chinese Journal of Integrative Medicine 29:8, pages 738-749.
Crossref
Abeer A. A. Salama, Rania Elgohary & Mohamed Ibrahim Fahmy. (2023) Protocatechuic acid ameliorates lipopolysaccharide‐induced kidney damage in mice via downregulation of TLR‐4‐mediated IKBKB/NF‐κB and MAPK/Erk signaling pathways. Journal of Applied Toxicology 43:8, pages 1119-1129.
Crossref
Jizi Zhou, Ying Zhao, Ping An, Huanqiang Zhao, Xiaotian Li & Yu Xiong. (2023) Hsa_circ_0002348 regulates trophoblast proliferation and apoptosis through miR-126-3p/BAK1 axis in preeclampsia. Journal of Translational Medicine 21:1.
Crossref
Xinhang Xia, Wenhu Pi, Meng Chen, Wei Wang, Danyang Cai, Xuequan Wang, Yanli Lan & Haihua Yang. (2023) Emerging roles of PHLPP phosphatases in lung cancer. Frontiers in Oncology 13.
Crossref
Suiqun Guo, Huiping Jiang, Yuanrun Deng, Yanqi Dong, Aiqi Yin, Qinghai Wang, Qiudai Lan, Yilin Zhang & Caiqiu Xu. (2023) Reduced 2,4 ‐dienoyl‐CoA reductase 1 is served as an unfavorable biomarker and is related to immune infiltration in cervical cancer . Journal of Obstetrics and Gynaecology Research.
Crossref
Rubén López-Cortés, Isabel Correa Pardo, Laura Muinelo-Romay, Almudena Fernández-Briera & Emilio Gil-Martín. (2023) Core Fucosylation Mediated by the FucT-8 Enzyme Affects TRAIL-Induced Apoptosis and Sensitivity to Chemotherapy in Human SW480 and SW620 Colorectal Cancer Cells. International Journal of Molecular Sciences 24:15, pages 11879.
Crossref
Ya Li, Yulin Wang, Qiang Ao, Xiaohui Li, Zhongbing Huang, Xiaoqiu Dou, Ning Mu, Ximing Pu, Juan Wang, Tunan Chen, Guangfu Yin, Hua Feng & Chuanliang Feng. (2023) Unique Chirality Selection in Neural Cells for D‐Matrix Enabling Specific Manipulation of Cell Behaviors. Advanced Materials.
Crossref
Raushan Chaudhary, Ananthesh L.Prakash Patil, Uday Mateti, Sanjit Sah, Aroop Mohanty, Rama Rath, Bijaya Padhi, Sumira Malik, Kadhim Jassim, Moustafa Al-Shammari, Yasir Waheed, Prakasini Satapathy, Joshuan Barboza, Alfonso Rodriguez-Morales & Ranjit Sah. (2023) System Biology Approach to Identify the Hub Genes and Pathways Associated with Human H5N1 Infection. Vaccines 11:7, pages 1269.
Crossref
Yingying Zheng, Zhengjun Zhang, Dejie Zheng, Pengfei Yi & Shaoqiang Wang. (2023) METTL14 promotes the development of diabetic kidney disease by regulating m6A modification of TUG1. Acta Diabetologica.
Crossref
Hasan Issa, Raj Bhayadia, Robert Winkler, Laura Elise Swart, Dirk Heckl & Jan-Henning Klusmann. (2023) Preclinical testing of miRNA-193b-3p mimic in acute myeloid leukemias. Leukemia 37:7, pages 1583-1587.
Crossref
Jing Wu, Jiayan Li, You Wu, Mengran Yang, Yunqin Chen, Naidong Wang, Ji Wang, Zhihang Yuan, Jine Yi & Chenglin Yang. (2023) Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice. Food and Chemical Toxicology 177, pages 113811.
Crossref
Xia Yang, Feixiang Long, Weixin Jia, Mingxin Zhang, Guanming Su, Ming Liao, Zhenling Zeng, Weisan Chen & Jianxin Chen. (2023) Artesunate inhibits PDE4 leading to intracellular cAMP accumulation, reduced ERK/MAPK signaling, and blockade of influenza A virus vRNP nuclear export. Antiviral Research 215, pages 105635.
Crossref
Hui Yuan, Yingying Zhao, Shumin Li, Jun Qin & Xiaowen Yu. (2023) Madecassoside ameliorates cisplatin‐induced nephrotoxicity by inhibiting activation of the mitogen activated protein kinase pathway. Environmental Toxicology 38:7, pages 1473-1483.
Crossref
Xiangyi Wu, Danqing Huang, Ye Xu, Guopu Chen & Yuanjin Zhao. (2023) Microfluidic Templated Stem Cell Spheroid Microneedles for Diabetic Wound Treatment. Advanced Materials 35:28.
Crossref
Li Jiang, Jingwei Lu, Yixuan Chen, Kexin Lyu, Longhai Long, Xiaoqiang Wang, Tianzhu Liu & Sen Li. (2023) Mesenchymal stem cells: An efficient cell therapy for tendon repair (Review). International Journal of Molecular Medicine 52:2.
Crossref
Yalçın ERZURUMLU, Deniz ÇATAKLI & Hatice Kübra DOĞAN. (2023) Prostat Kanseri Hücrelerinde Kafein Sisplatinin Anti-tümorijenik Etkisini GüçlendirirCaffeine Potentiate the Anti-tumorigenic Effect of Cisplatin in Prostate Cancer Cells. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 10:2, pages 90-97.
Crossref
Wei Fan, Shuangli Lan, Yunkang Yang & Jie Liang. (2023) Network pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of Huang–Qi–Gui–Zhi–Wu–Wu decoction against deep vein thrombosis. Journal of Orthopaedic Surgery and Research 18:1.
Crossref
Qi-chun Zhou, Shi-lin Xiao, Ru-kun Lin, Chan Li, Zhi-jie Chen, Yi-fei Chen, Chao-hua Luo, Zhi-xian Mo & Ying-bo Lin. (2023) Polysaccharide of Alocasia cucullata Exerts Antitumor Effect by Regulating Bcl-2, Caspase-3 and ERK1/2 Expressions during Long-Time Administration. Chinese Journal of Integrative Medicine.
Crossref
Ming-Ming Zhang, Jing-Wei Zhao, Zhi-Qiang Li, Jing Shao & Xi-Yan Gao. (2023) Acupuncture at Back-Shu point improves insomnia by reducing inflammation and inhibiting the ERK/NF-κB signaling pathway. World Journal of Psychiatry 13:6, pages 340-350.
Crossref
Zhendong Liu, Wenjia Liang, Qingyun Zhu, Xingbo Cheng, Rongjun Qian & Yanzheng Gao. (2023) PSRC1 Regulated by DNA Methylation Is a Novel Target for LGG Immunotherapy. Journal of Molecular Neuroscience.
Crossref
Yong Meng, Rui Li, Shuaiming Geng, Wenhao Chen, Weirong Jiang, Zhiwen Li, Ji Hao & Zhen Xu. (2023) GABRP Promotes the Metastasis of Pancreatic Cancer by Activation of the MEK/ERK Signaling Pathway. Biochemical Genetics.
Crossref
Kai Liu, Yuanxin Chen, Feiyu Cai, Xin Wang, Chenchen Fan, Peng Ren, Aihemaitijiang Yusufu & Yanshi Liu. (2023) The Effect of Distraction Osteogenesis on Peripheral Nerve Regeneration in Rats: A Preliminary Study In Vivo. Journal of Tissue Engineering and Regenerative Medicine 2023, pages 1-9.
Crossref
Yu-Jiao Li, Xin-Liang Wang, Ling-Yu Shi, Zong-Yi Wang, Zi-Ang Zhao, Shu-Chao Ge & Bing Hu. (2023) DUSP2 Deletion Inhibits Macrophage Migration by Inhibiting ERK Activation in Zebrafish. Fishes 8:6, pages 310.
Crossref
Maja Owe-Larsson, Jan Pawłasek, Tomasz Piecha, Alicja Sztokfisz-Ignasiak, Mikołaj Pater & Izabela R. Janiuk. (2023) The Role of Cocaine- and Amphetamine-Regulated Transcript (CART) in Cancer: A Systematic Review. International Journal of Molecular Sciences 24:12, pages 9986.
Crossref
Jia Zhang, Lixia Zhao, Yuting Fu, Fangyuan Liu, Zixin Wang, Yunxia Li, Gaoping Zhao, Wei Sun, Baojiang Wu, Yongli Song, Shaohua Li, Chunxia Hao, Bilige Wuyun, Rihan Wu, Moning Liu, Guifang Cao, Buhe Nashun, M Azim Surani, Qingyuan Sun, Siqin Bao, Pentao Liu & Xihe Li. (2023) Reprogramming efficiency and pluripotency of mule iPSCs over its parents. Biology of Reproduction 108:6, pages 887-901.
Crossref
Fernanda Andrade, Júlia German-Cortés, Sara Montero, Pilar Carcavilla, Diego Baranda-Martínez-Abascal, Marc Moltó-Abad, Joaquín Seras-Franzoso, Zamira Vanessa Díaz-Riascos, Diana Rafael & Ibane Abasolo. (2023) The Nanotechnology-Based Approaches against Kirsten Rat Sarcoma-Mutated Cancers. Pharmaceutics 15:6, pages 1686.
Crossref
Jingni Zhang, Hongjuan Wang, Huan Chen, Yong Liu, An Wang, Hongwei Hou & Qingyuan Hu. (2023) Acetaldehyde induces similar cytotoxic and genotoxic risks in BEAS-2B cells and HHSteCs: involvement of differential regulation of MAPK/ERK and PI3K/AKT pathways. Environmental Science and Pollution Research 30:32, pages 79423-79436.
Crossref
Zongyu Liu, Xin Jin, Yulin Miao, Ping Wang, Yang Gu, Xiaozhao Shangguan, Lijing Chen & Guiling Wang. (2023) Identification and Characterization of C-Mos in Pearl Mussel Hyriopsis cumingii and Its Role in Gonadal Development. Biomolecules 13:6, pages 931.
Crossref
Lei Lei, Mu Jing, Zheng Yingce, Zhang Pei & Liu Yun. (2023) Selenium deficiency causes oxidative stress and activates inflammation, apoptosis, and necroptosis in the intestine of weaned calves. Metallomics 15:6.
Crossref
Zijian Zhu, Shaogang Qin, Tuo Zhang, Meina He, Wenying Zheng, Ting Zhao, Meng Gao, Ziqi Chen, Bo Zhou, Guoliang Xia & Chao Wang. (2023) Pregranulosa cell–derived FGF23 protects oocytes from premature apoptosis during primordial follicle formation by inhibiting p38 MAPK in mice. Journal of Biological Chemistry 299:6, pages 104776.
Crossref
Yuan Su, Xuyang Gao, Yu Wang, Xuying Li, Weipeng Zhang & Junxing Zhao. (2023) Astragalus polysaccharide promotes sheep satellite cell differentiation by regulating miR-133a through the MAPK/ERK signaling pathway. International Journal of Biological Macromolecules 239, pages 124351.
Crossref
Xiao-Juan Zhan, Rui Wang, Xiong-Ri Kuang, Jue-Yu Zhou & Xiao-Lei Hu. (2023) Elevated expression of myosin VI contributes to breast cancer progression via MAPK/ERK signaling pathway. Cellular Signalling 106, pages 110633.
Crossref
Qiuping Zhou, Lanfen Lin, Haiyan Li, Yichen Li, Nan Liu, Huifang Wang, Shuqi Jiang, Qian Li, Zhuo Chen, Yiyan Lin, Hui Jin & Yiyu Deng. (2023) Intrahippocampal injection of IL ‐1β upregulates Siah1‐mediated degradation of synaptophysin by activation of the ERK signaling in male rat . Journal of Neuroscience Research 101:6, pages 930-951.
Crossref
Fanshuo Yin, Xin Zhang, Zaihong Zhang, Meichen Zhang, Yunyi Yin, Yanmei Yang & Yanhui Gao. (2023) ERK/PKM2 Is Mediated in the Warburg Effect and Cell Proliferation in Arsenic-Induced Human L-02 Hepatocytes. Biological Trace Element Research.
Crossref
Ting-ting Chen, Xiu-qin Li, Nan Li, Ya-ping Xu, Yu-han Wang, Zi-ying Wang, Sheng-nan Zhang, Meng Qi, Shi-hao Zhang, Wei Wei, Hua Wang & Wu-yi Sun. (2023) β-arrestin2 deficiency ameliorates S-100-induced autoimmune hepatitis in mice by inhibiting infiltration of monocyte-derived macrophage and attenuating hepatocyte apoptosis. Acta Pharmacologica Sinica.
Crossref
Arturo Valle-Mendiola, Adriana Gutiérrez-Hoya & Isabel Soto-Cruz. (2023) JAK/STAT Signaling and Cervical Cancer: From the Cell Surface to the Nucleus. Genes 14:6, pages 1141.
Crossref
Paweł Nałęcz-Jawecki, Paolo Armando Gagliardi, Marek Kochańczyk, Coralie Dessauges, Olivier Pertz & Tomasz Lipniacki. (2023) The MAPK/ERK channel capacity exceeds 6 bit/hour. PLOS Computational Biology 19:5, pages e1011155.
Crossref
Sara J. Knowles, April M. Stafford, Tariq Zaman, Kartik Angara, Michael R. Williams, Jason M. Newbern & Daniel Vogt. (2023) Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs. Development 150:10.
Crossref
Magdalena Szczerbowska-Boruchowska, Kaja Piana, Artur D. Surowka, Mateusz Czyzycki, Pawel Wrobel, Maciej Szymkowski & Agata Ziomber-Lisiak. (2023) A combined X-ray fluorescence and infrared microspectroscopy study for new insights into elemental-biomolecular obesity-induced changes in rat brain structures. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 293, pages 122478.
Crossref
Qing-yuan OUYANG, Heng-li XIE, Shen-qiang HU, Cong LAN, Ming-xia RAN, Ji-wei HU, Hua HE, Liang LI, He-he LIU, Hao QU & Ji-wen WANG. (2023) Comparative Genomics Study between High and Low Laying Goose Breeds Reveals the Important Role of ESR1 in Laying Ability. Journal of Integrative Agriculture.
Crossref
Homeyra Seydi, Kosar Nouri, Niloufar Rezaei, Atena Tamimi, Moustapha Hassan, Hamed Mirzaei & Massoud Vosough. (2023) Autophagy orchestrates resistance in hepatocellular carcinoma cells. Biomedicine & Pharmacotherapy 161, pages 114487.
Crossref
Layanne Nascimento Fraga, Dragan Milenkovic, Sara Lima Anacleto, Michelle Salemi, Franco Maria Lajolo & Neuza Mariko Aymoto Hassimotto. (2023) Citrus flavanone metabolites significantly modulate global proteomic profile in pancreatic β-cells under high-glucose-induced metabolic stress. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1871:3, pages 140898.
Crossref
Francisca M. Real, Miguel Lao‐Pérez, Miguel Burgos, Stefan Mundlos, Darío G. Lupiáñez, Rafael Jiménez & Francisco J. Barrionuevo. (2022) Cell adhesion and immune response, two main functions altered in the transcriptome of seasonally regressed testes of two mammalian species. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 340:3, pages 231-244.
Crossref
Sung‐Won Kim, Gwang‐Bum Im, Yeong Hwan Kim & Suk Ho Bhang. (2022) Fortifying angiogenic efficacy of conditioned media using phototoxic‐free blue light for wound healing. Bioengineering & Translational Medicine 8:3.
Crossref
Ni Ni, Min Ge, Rui Huang, Dandan Zhang, Han Lin, Yahan Ju, Zhimin Tang, Huiqin Gao, Huifang Zhou, Yu Chen & Ping Gu. (2023) Thermodynamic 2D Silicene for Sequential and Multistage Bone Regeneration. Advanced Healthcare Materials 12:13.
Crossref
Dianbao Zhang, Yunmei Fu, Ying Liu, Yifan Wu, Jiayu Chen, Luting Zhang, Rui Wang, Zaixing Chen & Tao Liu. (2023) 8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells. International Journal of Molecular Sciences 24:9, pages 8039.
Crossref
Xin Cao, Tao Li, Yongshen Tian, Yajing Tian, Chuang Gao, Dongmei Zhang & Yu Song. (2023) BIBF1120 Protects against Diabetic Retinopathy through Neovascularization-Related Molecules and the MAPK Signaling Pathway. Journal of Ophthalmology 2023, pages 1-12.
Crossref
Jiaxin Lv, Qiaona Wang, Dongyu Liu, Catherine Huihan Chu, Heyang Zhou, Guoqing Li, Jin Wu, Kunzhan Cai & Chunbo Tang. (2023) Calcium phytate reverses high glucose‐inhibited osteogenesis of BMSCs via the MAPK / JNK pathway . Oral Diseases.
Crossref
Bo Sun, Liang Chen, Zhe Qu, Yan-Wei Yang, Yu-Fa Miao, Rui-Li Wang, Xiao-Bing Zhou & Bo Li. (2023) Screening Differential Expression Profiles of Urinary microRNAs in a Gentamycin-Induced Acute Kidney Injury Canine Model. Kidney and Dialysis 3:2, pages 204-218.
Crossref
Saugat Khanal, Neha Bhavnani, Amy Mathias, Jason Lallo, Shreya Gupta, Vahagn Ohanyan, Jessica M. Ferrell & Priya Raman. (2023) Deletion of Smooth Muscle O-GlcNAc Transferase Prevents Development of Atherosclerosis in Western Diet-Fed Hyperglycemic ApoE-/- Mice In Vivo. International Journal of Molecular Sciences 24:9, pages 7899.
Crossref
Jinbao Wei, Huanrui Zheng, Guokai Li, Zichun Chen, Gengjing Fang & Jianying Yan. (2023) Involvement of oxytocin receptor deficiency in psychiatric disorders and behavioral abnormalities. Frontiers in Cellular Neuroscience 17.
Crossref
Julio Rodrigo Escartín-Gutiérrez, Mariana Ponce-Figueroa, Miguel Ángel Torres-Vega, Leopoldo Aguilar-Faisal & Paula Figueroa-Arredondo. (2023) Transcriptional Activation of a Pro-Inflammatory Response (NF-κB, AP-1, IL-1β) by the Vibrio cholerae Cytotoxin (VCC) Monomer through the MAPK Signaling Pathway in the THP-1 Human Macrophage Cell Line. International Journal of Molecular Sciences 24:8, pages 7272.
Crossref
Haoyuan Wang, Lei Zhang, Bin Liu, Jianzhi Su & Xiaochen Ni. (2023) Role of CCT4/ErbB signaling in nephroblastoma: Implications for a biomarker of Wilms tumor. Medicine 102:15, pages e33219.
Crossref
Luís Arpa, Carlos Batlle, Peijin Jiang, Carme Caelles, Jorge Lloberas & Antonio Celada. (2023) Distinct Responses to IL4 in Macrophages Mediated by JNK. Cells 12:8, pages 1127.
Crossref
Pedram Iranmanesh, Amirhossein Vedaei, Sadra Salehi-Mazandarani, Parvaneh Nikpour, Saber Khazaei, Abbasali Khademi, Kerstin M. Galler, Mohammad-Hossein Nekoofar & Paul M. H. Dummer. (2023) MicroRNAs-mediated regulation of the differentiation of dental pulp-derived mesenchymal stem cells: a systematic review and bioinformatic analysis. Stem Cell Research & Therapy 14:1.
Crossref
A-bin You, Hu Yang, Chun-ping Lai, Wen Lei, Lu Yang, Jia-lin Lin, Shun-cui Liu, Nan Ding & Feng Ye. (2023) CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3. Cell Death & Disease 14:4.
Crossref
Shiqing Sun, Kai Zhang, Yuliang Wang, Zijun Zhou, Lihong Wang, Hong Zhao & Yu Zhang. (2023) Pharmacodynamic structure of deer antler base protein and its mammary gland hyperplasia inhibition mechanism by mediating Raf-1/MEK/ERK signaling pathway activation. Food & Function 14:7, pages 3319-3331.
Crossref
Yanzhi Guo, Yuqiao Han, Ziyan Li, Jiali Ji, Tong Zhu, Yijie Du & Suzhen Dong. (2023) A new inhibitor of human peptide deformylase suppresses cell proliferation and induces cell apoptosis and autophagy in cancers. Anti-Cancer Drugs 34:4, pages 483-494.
Crossref
Benxu Cheng, Yunlin Wei, Lili Guerra, Rozena Shirvani-Arani, Santiago Balderas, Laura Valdez, Andrew Tsin & Xiaoqian Fang. (2023) Anti-cancer effect of Cissus quadrangularis on human glioblastoma cells . RPS Pharmacy and Pharmacology Reports 2:2.
Crossref
Yin Wang, Junfeng Gao, Liqiao Sun, Qi Li, Ning Kang, Chen Gao & Tong Li. (2023) Jia-Wei-Si-Miao-Yong-An Fang stimulates the healing of acute radiation-induced cutaneous wounds through MAPK/ERK pathway. Journal of Ethnopharmacology 306, pages 116180.
Crossref
Na Li, Chun-Yan Yao, Jun Diao, Xiao-Ling Liu, En-Jie Tang, Qing-Song Huang, Yu-Meng Zhou, Yue-Gu Hu, Xiu-Kuan Li, Jin-Yun Long, Hua Xiao, Da-Wei Li, Ning Du, Ya-Fei Li, Peng Luo & Tong-Jian Cai. (2023) The role of MAPK/NF-κB-associated microglial activation in T-2 toxin-induced mouse learning and memory impairment. Food and Chemical Toxicology 174, pages 113663.
Crossref
He Zhang, Zhouyi Xu, Haojun Gao & Qinyuan Zhang. (2023) Systematic analysis on the mechanism of Zhizi-Bopi decoction against hepatitis B via network pharmacology and molecular docking. Biotechnology Letters 45:4, pages 463-478.
Crossref
W. Aline Ingelson‐Filpula, Hanane Hadj‐Moussa & Kenneth B. Storey. (2023) MicroRNA transcriptomics in liver of the freeze‐tolerant gray tree frog ( Dryophytes versicolor) indicates suppression of energy‐expensive pathways . Cell Biochemistry and Function 41:3, pages 309-320.
Crossref
Wenfei Li, Chuanfeng Ke, Cuiyan Yang, Jieyao Li, Qikui Chen, Zhongsheng Xia & Jihao Xu. (2023) LncRNA DICER1‐AS1 promotes colorectal cancer progression by activating the MAPK / ERK signaling pathway through sponging miR ‐650 . Cancer Medicine 12:7, pages 8351-8366.
Crossref
Tahir Mehmood, Rath Pichyangkura & Chatchai Muanprasat. (2023) Chitosan Oligosaccharide Promotes Junction Barrier through Modulation of PI3K/AKT and ERK Signaling Intricate Interplay in T84 Cells. Polymers 15:7, pages 1681.
Crossref
Jing Mu, Lei Lei, Yingce Zheng, Jia Liu, Jie Li, Ding Li, Guanbo Wang & Yun Liu. (2023) Oxidative Stress Induced by Selenium Deficiency Contributes to Inflammation, Apoptosis and Necroptosis in the Lungs of Calves. Antioxidants 12:4, pages 796.
Crossref
Emily Ling-Lin Pai, April M. Stafford & Daniel Vogt. (2023) Cellular signaling impacts upon GABAergic cortical interneuron development. Frontiers in Neuroscience 17.
Crossref
Xiaoxiao Zhang, Shuhua Gu, Shunyi Shen, Tao Luo, Haiyi Zhao, Sijia Liu, Jingjie Feng, Maosheng Yang, Laqi Yi, Zhaohan Fan, Yu Liu & Rui Han. (2023) Identification of Circular RNA Profiles in the Liver of Diet-Induced Obese Mice and Construction of the ceRNA Network. Genes 14:3, pages 688.
Crossref
Timothy A. Donlon, Brian J. Morris, Randi Chen, Eunjung Lim, Eric K. Morgen, Kristen Fortney, Naisha Shah, Kamal H. Masaki & Bradley J. Willcox. (2023) Proteomic basis of mortality resilience mediated by FOXO3 longevity genotype. GeroScience 45:4, pages 2303-2324.
Crossref
Shazia Shafique, Ume Attia, Sobiya Shafique, Bushra Tabassum, Naureen Akhtar, Ayman Naeem & Qamar Abbas. (2023) Management of mung bean leaf spot disease caused by Phoma herbarum through Penicillium janczewskii metabolites mediated by MAPK signaling cascade. Scientific Reports 13:1.
Crossref
Tianxi Zhang, Yanbo Ren, Chao Yang, Kefyalew Gebeyew, Min Gao, Zhixiong He & Zhiliang Tan. (2023) An integrated transcriptome and microbial community analysis reveals potential mechanisms for increased immune responses when replacing silybum marianum meal with soybean meal in growing lambs. Frontiers in Microbiology 14.
Crossref
Xiaoqing Wen, Xia Zhou & Ling Guo. (2023) Berberine Inhibits Endothelial Cell Proliferation via Repressing ERK1/2 Pathway. Natural Product Communications 18:3, pages 1934578X2311526.
Crossref
M. Watanabe, M. Okamoto, S. Komichi, H. Huang, S. Matsumoto, K. Moriyama, J. Ohshima, S. Abe, M. Morita, M. Ali, K. Takebe, I. Kozaki, A. Fujimoto, K. Kanie, R. Kato, K. Uto, M. Ebara, A. Yamawaki-Ogata, Y. Narita, Y. Takahashi & M. Hayashi. (2022) Novel Functional Peptide for Next-Generation Vital Pulp Therapy. Journal of Dental Research 102:3, pages 322-330.
Crossref
Rongsheng Xiong, Ke Xu & Xiaoyan Feng. (2023) SPC25 Promotes the Proliferation and Migration of Esophageal Carcinoma by Activating the MAPK/ERK Pathway. Journal of Biomedical Nanotechnology 19:3, pages 424-430.
Crossref
Igor M. Souza-Silva, U. Muscha Steckelings & Kasper Bostlund Assersen. (2023) The role of vasoactive peptides in skin homeostasis—focus on adiponectin and the kallikrein-kinin system. American Journal of Physiology-Cell Physiology 324:3, pages C741-C756.
Crossref
Vasantha Kalaivani, Mahesh S. Krishna, Asokan Aneesh Kumar, Gopika Satheesh & Abdul Jaleel. (2023) O‐glycan structures in apo(a) subunit of human lipoprotein(a) suppresses the pro‐angiogenic activity of galectin‐1 on human umbilical vein endothelial cells. The FASEB Journal 37:3.
Crossref
Shoto Sasaki, Takayuki Negishi, Takamasa Tsuzuki & Kazunori Yukawa. (2023) Methylmercury-induced reactive oxygen species-dependent and independent dysregulation of MAP kinase-related signaling pathway in cultured normal rat cerebellar astrocytes. Toxicology 487, pages 153463.
Crossref
Hoon Kim, Hongbum Park, Byungdoo Hwang, Soobin Kim, Yung Hyun Choi, Wun-Jae Kim & Sung-Kwon Moon. (2023) Bisphenol A exposure inhibits vascular smooth muscle cell responses: Involvement of proliferation, migration, and invasion. Environmental Toxicology and Pharmacology 98, pages 104060.
Crossref
Lan Ma, Chengmei Zhang, Yu Gui, Tingling Zou, Shuhua Xi & Xiaoying Guo. (2023) Fluoride regulates the differentiation and atrophy through FGF21/ERK signaling pathway in C2C12 cells. Ecotoxicology and Environmental Safety 252, pages 114626.
Crossref
Yuan-chun Wang, Jian-rong Hui, Gang Xiao & Qiao-lin Ma. (2022) Mechanism of Key Ingredient of Astragalus membranaceus on Lung Adenocarcinoma via PI3K/AKT Signaling Clarified by Utilizing Network Pharmacology Approach and Experimental Validation. Chinese Journal of Integrative Medicine 29:3, pages 244-252.
Crossref
Xin-Ya Shen, Yu Han, Zhen-Kun Gao, Ping-Ping Han & Xia Bi. (2022) Pre exposure to enriched environment alleviates brain injury after ischemia-reperfusion by inhibiting p38MAPK/STAT1 pathway. Molecular Biology Reports 50:3, pages 2243-2255.
Crossref
Shixi Zhang, Yuqing Pan, Zhiyuan Mao, Jiahui Zhang, Kunxi Zhang, Jingbo Yin & Chen Wang. (2022) Hyaluronic acid‐ g ‐lipoic acid granular gel for promoting diabetic wound healing . Bioengineering & Translational Medicine 8:2.
Crossref
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