Citations (130)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (17)
Md Harunur Rashid. (2022) Full-length recombinant antibodies from Escherichia coli: production, characterization, effector function (Fc) engineering, and clinical evaluation. mAbs 14:1.
Read now
Read now
Mohamed A. Alfaleh, Ayat Zawawi, Sawsan S. Al-Amri & Anwar M. Hashem. (2022) David versus goliath: ACE2-Fc receptor traps as potential SARS-CoV-2 inhibitors. mAbs 14:1.
Read now
Read now
Dhuha H Nawab. (2021) Vaccinal antibodies: Fc antibody engineering to improve the antiviral antibody response and induce vaccine-like effects. Human Vaccines & Immunotherapeutics 17:12, pages 5532-5545.
Read now
Read now
Peifeng Tang, Zhijun Tan, Vivekh Ehamparanathan, Tingwei Ren, Laurel Hoffman, Cheng Du, Yuanli Song, Li Tao, Angela Lewandowski, Sanchayita Ghose, Zheng Jian Li & Shijie Liu. (2020) Optimization and kinetic modeling of interchain disulfide bond reoxidation of monoclonal antibodies in bioprocesses. mAbs 12:1.
Read now
Read now
Michael W. Handlogten, Li Peng, Elizabeth A. Christian, Weichen Xu, Shihua Lin, Raghavan Venkat, William Dall’Acqua & Sanjeev Ahuja. (2020) Prevention of Fab-arm exchange and antibody reduction via stabilization of the IgG4 hinge region. mAbs 12:1.
Read now
Read now
Lily Pei-Yao Liu-Shin, Adam Fung, Arun Malhotra & Gayathri Ratnaswamy. (2018) Evidence of disulfide bond scrambling during production of an antibody-drug conjugate. mAbs 10:8, pages 1190-1199.
Read now
Read now
Paul Malik & Andrea Edginton. (2018) Pediatric physiology in relation to the pharmacokinetics of monoclonal antibodies. Expert Opinion on Drug Metabolism & Toxicology 14:6, pages 585-599.
Read now
Read now
Danlin Yang, Rachel Kroe-Barrett, Sanjaya Singh, Christopher J. Roberts & Thomas M. Laue. (2017) IgG cooperativity – Is there allostery? Implications for antibody functions and therapeutic antibody development. mAbs 9:8, pages 1231-1252.
Read now
Read now
Dietmar Reusch, Markus Haberger, Tobias Kailich, Anna-Katharina Heidenreich, Michael Kampe, Patrick Bulau & Manfred Wuhrer. (2014) High-throughput glycosylation analysis of therapeutic immunoglobulin G by capillary gel electrophoresis using a DNA analyzer. mAbs 6:1, pages 185-196.
Read now
Read now
David Ouellette, Chris Chumsae, Anca Clabbers, Czeslaw Radziejewski & Ivan Correia. (2013) Comparison of the in vitro and in vivo stability of a succinimide intermediate observed on a therapeutic IgG1 molecule. mAbs 5:3, pages 432-444.
Read now
Read now
Ivan Correia, Joyce Sung, Randall Burton, Clarissa G. Jakob, Bridget Carragher, Tariq Ghayur & Czeslaw Radziejewski. (2013) The structure of dual-variable-domain immunoglobulin molecules alone and bound to antigen. mAbs 5:3, pages 364-372.
Read now
Read now
Marcella Yu, Darren Brown, Chae Reed, Shan Chung, Jeff Lutman, Eric Stefanich, Anne Wong, Jean-Philippe Stephan & Robert Bayer. (2012) Production, characterization and pharmacokinetic properties of antibodies with N-linked Mannose-5 glycans. mAbs 4:4, pages 475-487.
Read now
Read now
Leslie Alessandri, David Ouellette, Aima Acquah, Mathew Rieser, David LeBlond, Mary Saltarelli, Czeslaw Radziejewski, Taro Fujimori & Ivan Correia. (2012) Increased serum clearance of oligomannose species present on a human IgG1 molecule. mAbs 4:4, pages 509-520.
Read now
Read now
Reema Piparia, David Ouellette, W. Blaine Stine, Christine Grinnell, Edit Tarcsa, Czeslaw Radziejewski & Ivan Correia. (2012) A high throughput capillary electrophoresis method to obtain pharmacokinetics and quality attributes of a therapeutic molecule in circulation. mAbs 4:4, pages 521-531.
Read now
Read now
Josef Vlasak & Roxana Ionescu. (2011) Fragmentation of monoclonal antibodies. mAbs 3:3, pages 253-263.
Read now
Read now
Alain Beck & Thierry Wurch. (2011) 6th Annual European Antibody Congress 2010. mAbs 3:2, pages 111-132.
Read now
Read now
Alain Beck. (2011) Biosimilar, biobetter and next generation therapeutic antibodies. mAbs 3:2, pages 107-110.
Read now
Read now
Articles from other publishers (113)
A. V. Nozdracheva & T. A. Semenenko. (2023) Assessment of the reliability of serological monitoring results based on biobank materials. Cardiovascular Therapy and Prevention 22:11, pages 3709.
Crossref
Crossref
Matthew Lohman, Hannah Rowe,Peter R. Andreana. 2023. Carbohydrate‐Based Therapeutics. Carbohydrate‐Based Therapeutics
201
221
.
Kosuke Oyama, Makoto Nakakido, Takatoshi Ohkuri, Hitomi Nakamura, Kouhei Tsumoto & Tadashi Ueda. (2023)
Enhancing thermal stability in the
CH
2
domain to suppress aggregation through the introduction of simultaneous disulfide bonds in
Pichia pastoris
. Protein Science 32:12.
Crossref
Crossref
Rémi Longuespée, Dirk Theile, Inka Zörnig, Jessica C. Hassel, Joshua Raoul Lindner, Walter E. Haefeli & Margaux Fresnais. (2022)
Molecular prediction of clinical response to
anti‐PD
‐1/
anti‐PD‐L1
immune checkpoint inhibitors: New perspectives for precision medicine and mass spectrometry‐based investigations
. International Journal of Cancer 153:2, pages 252-264.
Crossref
Crossref
D. Nixdorf, M. Sponheimer, D. Berghammer, F. Engert, U. Bader, N. Philipp, M. Kazerani, T. Straub, L. Rohrbacher, L. Wange, S. Dapa, D. Atar, C. M. Seitz, K. Brandstetter, A. Linder, M. von Bergwelt, H. Leonhardt, J. Mittelstaet, A. Kaiser, V. Bücklein & M. Subklewe. (2023) Adapter CAR T cells to counteract T-cell exhaustion and enable flexible targeting in AML. Leukemia 37:6, pages 1298-1310.
Crossref
Crossref
Joachim Schuster, Vinay Kamuju & Roman Mathaes. (2023) Protein Stability After Administration: A Physiologic Consideration. Journal of Pharmaceutical Sciences 112:2, pages 370-376.
Crossref
Crossref
Andrey E. Urusov, Anna S. Tolmacheva, Kseniya S. Aulova & Georgy A. Nevinsky. (2023) Autoantibody–Abzymes with Catalase Activity in Experimental Autoimmune Encephalomyelitis Mice. Molecules 28:3, pages 1330.
Crossref
Crossref
Eva Schlein, Stina Syvänen, Johanna Rokka, Tobias Gustavsson, Raffaella Rossin, Marc Robillard, Jonas Eriksson & Dag Sehlin. (2022) Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging. Molecular Pharmaceutics 19:11, pages 4111-4122.
Crossref
Crossref
Anna S. Tolmacheva, Kseniya S. Aulova, Andrey E. Urusov, Vasiliy B. Doronin & Georgy A. Nevinsky. (2022) Antibodies-Abzymes with Antioxidant Activities in Two Th and 2D2 Experimental Autoimmune Encephalomyelitis Mice during the Development of EAE Pathology. Molecules 27:21, pages 7527.
Crossref
Crossref
Darshana Jani, Robin Marsden, Michele Gunsior, Laura Schild Hay, Bethany Ward, Kyra J. Cowan, Mitra Azadeh, Breann Barker, Liching Cao, Kristin R. Closson, Kelly Coble, Sanjay L. Dholakiya, Julie Dusseault, Amanda Hays, Carina Herl, Michael E. Hodsdon, Susan C. Irvin, Susan Kirshner, Gerry Kolaitis, Nadia Kulagina, Seema Kumar, Ching Ha Lai, Francesco Lipari, Susana Liu, Keith D. Merdek, Ioana R. Moldovan, Reza Mozaffari, Luying Pan, Corina Place, Veerle Snoeck, Marta Starcevic Manning, Dennis Stocker, Magdalena Tary-Lehmann, Amy Turner, Inna Vainshtein, Daniela Verthelyi, William T. Williams, Haoheng Yan, Weili Yan, Lili Yang, Lin Yang, Jennifer Zemo & Zhandong Don Zhong. (2022) Anti-drug Antibody Sample Testing and Reporting Harmonization. The AAPS Journal 24:6.
Crossref
Crossref
Andrew Kleinberg, Rachel Joseph, Yuan Mao & Ning Li. (2022) Ultrasensitive disulfide scrambling analysis of mAbs by LC-MS with post-column reduction and glycine signal enhancement. Analytical Biochemistry 653, pages 114773.
Crossref
Crossref
Dhiman Ray, Riley Nicolas Quijano & Ioan Andricioaei. (2022) Point mutations in SARS-CoV-2 variants induce long-range dynamical perturbations in neutralizing antibodies. Chemical Science 13:24, pages 7224-7239.
Crossref
Crossref
Ai Miyamoto, Tomoko Honjo, Mirei Masui, Rie Kinoshita, Hiromi Kumon, Kazuhiro Kakimi & Junichiro Futami. (2022) Engineering Cancer/Testis Antigens With Reversible S-Cationization to Evaluate Antigen Spreading. Frontiers in Oncology 12.
Crossref
Crossref
Anna S. Tolmacheva & Georgy A. Nevinsky. (2022) Essential Protective Role of Catalytically Active Antibodies (Abzymes) with Redox Antioxidant Functions in Animals and Humans. International Journal of Molecular Sciences 23:7, pages 3898.
Crossref
Crossref
Yukako Senga, Toshihiko Ogura, Hiroshi Imamura & Shinya Honda. 2022. Therapeutic Antibodies. Therapeutic Antibodies
219
239
.
Hristo L. Svilenov, Julia Sacherl, Alwin Reiter, Lisa S. Wolff, Cho-Chin Cheng, Marcel Stern, Vincent Grass, Martin Feuerherd, Frank-Peter Wachs, Nicole Simonavicius, Susanne Pippig, Florian Wolschin, Oliver T. Keppler, Johannes Buchner, Carsten Brockmeyer & Ulrike Protzer. (2021) Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein. Antiviral Research 196, pages 105197.
Crossref
Crossref
Noritaka Hashii & Akio Ishii-Watabe. (2021) Evaluation of structural properties of therapeutic antibodies by multi-attribute methodMulti-attribute methodによる抗体医薬品の構造特性評価. Drug Delivery System 36:5, pages 342-352.
Crossref
Crossref
Praopim Limsakul, Chi‐Wei Man, Qin Peng, Shaoying Lu & Yingxiao Wang. 2021. Protein Engineering. Protein Engineering
377
402
.
Tingwei Ren, Zhijun Tan, Vivekh Ehamparanathan, Angela Lewandowski, Sanchayita Ghose & Zheng Jian Li. (2021) Antibody disulfide bond reduction and recovery during biopharmaceutical process development—A review. Biotechnology and Bioengineering 118:8, pages 2829-2844.
Crossref
Crossref
Shravan Sreenivasan, Deepak Sonawat, Shyamapada Mandal, Kedar Khare & Anurag S. Rathore. (2021) Novel semi-automated fluorescence microscope imaging algorithm for monitoring IgG aggregates in serum. Scientific Reports 11:1.
Crossref
Crossref
Dante Descalzi‐Montoya, Rachel A. Montel, Keith Smith, Eugenia Dziopa, Andrieh Darwich, Zheng Yang, Constantine Bitsaktsis, Robert Korngold & David Sabatino. (2020) Synthetic Antibody Mimics Based on Cancer‐Targeting Immunostimulatory Peptides. ChemBioChem 22:9, pages 1589-1596.
Crossref
Crossref
Alexandra Albus, Yannick Kronimus, Sascha Neumann, Natascha Vidovic, André Frenzel, Philipp Kuhn, Marc Seifert, Tamar Ziehm, Hendrik van der Wurp & Richard Dodel. (2021) Effects of a Multimerized Recombinant Autoantibody Against Amyloid-β. Neuroscience 463, pages 355-369.
Crossref
Crossref
Anna S. Tolmacheva, Kseniya S. Aulova, Andrey E. Urusov, Irina A. Orlovskaya & Georgy A. Nevinsky. (2021) Increase in Autoantibodies-Abzymes with Peroxidase and Oxidoreductase Activities in Experimental Autoimmune Encephalomyelitis Mice during the Development of EAE Pathology. Molecules 26:7, pages 2077.
Crossref
Crossref
Joydeb Majumder & Tamara Minko. (2021) Recent Developments on Therapeutic and Diagnostic Approaches for COVID-19. The AAPS Journal 23:1.
Crossref
Crossref
Alexandre Goyon, Daniel McDonald, Szabolcs Fekete, Davy Guillarme & Cinzia Stella. (2020) Development of an innovative salt-mediated pH gradient cation exchange chromatography method for the characterization of therapeutic antibodies. Journal of Chromatography B 1160, pages 122379.
Crossref
Crossref
Umbreen Hafeez, Sagun Parakh, Hui K. Gan & Andrew M. Scott. (2020) Antibody–Drug Conjugates for Cancer Therapy. Molecules 25:20, pages 4764.
Crossref
Crossref
Yosuke Mizuno & Tetsushi Taguchi. (2020) Anti-Inflammatory and Tissue Adhesion Properties of an α-Linolenic Acid-Modified Gelatin-Based In Situ Hydrogel. ACS Applied Bio Materials 3:9, pages 6204-6213.
Crossref
Crossref
Giuseppe Caruso, Nicolò Musso, Margherita Grasso, Angelita Costantino, Giuseppe Lazzarino, Fabio Tascedda, Massimo Gulisano, Susan M. Lunte & Filippo Caraci. (2020) Microfluidics as a Novel Tool for Biological and Toxicological Assays in Drug Discovery Processes: Focus on Microchip Electrophoresis. Micromachines 11:6, pages 593.
Crossref
Crossref
Natalia I. MajewskaMax L. TejadaMichael J. BetenbaughNitin Agarwal. (2020)
N-
Glycosylation of IgG and IgG-Like Recombinant Therapeutic Proteins: Why Is It Important and How Can We Control It?
. Annual Review of Chemical and Biomolecular Engineering 11:1, pages 311-338.
Crossref
Crossref
Ivan Yu. Kompaneets, Evgeny A. Ermakov, Sergey E. Sedykh, Valentina N. Buneva & Georgy A. Nevinsky. (2020) IgGs from Human Milk Hydrolyze microRNAs. Molecules 25:10, pages 2366.
Crossref
Crossref
Wenjing Li, Neha Srikumar, William F. Forrest, Diego Ellerman, Chen Gu, Robert Tchelepi, Greg A. Lazar, Yichin Liu & John C. Tran. (2020) Characterizing and Quantitating Therapeutic Tethered Multimeric Antibody Degradation Using Affinity Capture Mass Spectrometry. Analytical Chemistry 92:10, pages 6839-6843.
Crossref
Crossref
Pariya Pourrostam-Ravadanaq, Kazem D. Safa & Hassan Abbasi. (2020) Study of imidazole performance as pseudo-affinity ligand in the purification of IgG from bovine milk. Analytical Biochemistry 597, pages 113693.
Crossref
Crossref
A.C. Marques, P.J. Costa, S. Velho & M.H. Amaral. (2020) Functionalizing nanoparticles with cancer-targeting antibodies: A comparison of strategies. Journal of Controlled Release 320, pages 180-200.
Crossref
Crossref
Thach H. Chu, Andrew R. Crowley, Iara Backes, Cheryl Chang, Matthew Tay, Thomas Broge, Marina Tuyishime, Guido Ferrari, Michael S. Seaman, Simone I. Richardson, Georgia D. Tomaras, Galit Alter, David Leib & Margaret E. Ackerman. (2020) Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies. PLOS Pathogens 16:2, pages e1008083.
Crossref
Crossref
Elena Bartkiene, Vita Lele, Vytaute Sakiene, Paulina Zavistanaviciute, Modestas Ruzauskas, Arunas Stankevicius, Juozas Grigas, Arnoldas Pautienius, Jurga Bernatoniene, Valdas Jakstas, Daiva Zadeike, Pranas Viskelis & Grazina Juodeikiene. (2020) Fermented, ultrasonicated, and dehydrated bovine colostrum: Changes in antimicrobial properties and immunoglobulin content. Journal of Dairy Science 103:2, pages 1315-1323.
Crossref
Crossref
Nicolas Aubert, Marie Brachet-Botineau, Giulia Emi de Olivera Preto, Isabelle Benz-de Bretagne, Hervé Watier & Guillaume Brachet. (2020) History, extensive characterization and challenge of anti-tetanus serum from World War I: exciting remnants and deceived hopes. Immunologic Research 68:1, pages 7-12.
Crossref
Crossref
Joachim Schuster, Atanas Koulov, Hanns-Christian Mahler, Pascal Detampel, Joerg Huwyler, Satish Singh & Roman Mathaes. (2020) In Vivo Stability of Therapeutic Proteins. Pharmaceutical Research 37:2.
Crossref
Crossref
Arutselvan Natarajan, Shyam M. Srinivas, Carmen Azevedo, Lacey Greene, Anne-Laure Bauchet, Erwan Jouannot, Anne-Sophie Lacoste-Bourgeacq, Isabelle Guizon, Patrick Cohen, Anne-Laure Naneix, Ohad Ilovich, Jordan Cisneros, Krithika Rupanarayan, Frederick T. Chin, Andrei Iagaru, Frederick M. Dirbas, Amer Karam & Sanjiv S. Gambhir. (2020) Two Patient Studies of a Companion Diagnostic Immuno-Positron Emission Tomography (PET) Tracer for Measuring Human CA6 Expression in Cancer for Antibody Drug Conjugate (ADC) Therapy. Molecular Imaging 19, pages 153601212093939.
Crossref
Crossref
Dennis R. Goulet & William M. Atkins. (2020) Considerations for the Design of Antibody-Based Therapeutics. Journal of Pharmaceutical Sciences 109:1, pages 74-103.
Crossref
Crossref
Feroz Jameel, Ehab M. Moussa, Brittney J. Mills & Peter M. Ihnat. 2020. Development of Biopharmaceutical Drug-Device Products. Development of Biopharmaceutical Drug-Device Products
265
297
.
Kyungbo Kim, Pereira Araujo, Nikhil Hebbar, Ziyuan Zhou, Xirong Zheng, Fang Zheng, Vivek M Rangnekar & Chang-Guo Zhan. (2019) Development of a novel prostate apoptosis response-4 (Par-4) protein entity with an extended duration of action for therapeutic treatment of cancer. Protein Engineering, Design and Selection 32:3, pages 159-166.
Crossref
Crossref
Yong Gu Lee, Haiyan Chu, Yingjuan Lu, Christopher P. Leamon, Madduri Srinivasarao, Karson S. Putt & Philip S. Low. (2019) Regulation of CAR T cell-mediated cytokine release syndrome-like toxicity using low molecular weight adapters. Nature Communications 10:1.
Crossref
Crossref
Emily R Bryan, Robert I McLachlan, Luk Rombauts, Darren J Katz, Anusch Yazdani, Kristofor Bogoevski, Crystal Chang, Michelle L Giles, Alison J Carey, Charles W Armitage, Logan K Trim, Eileen A McLaughlin & Kenneth W Beagley. (2019) Detection of chlamydia infection within human testicular biopsies. Human Reproduction 34:10, pages 1891-1898.
Crossref
Crossref
Peter P. Reader, Rouslan V. Olkhov, Shaun Reeksting, Anneke Lubben, Christopher J. Hyde & Andrew M. Shaw. (2019) A rapid and quantitative technique for assessing IgG monomeric purity, calibrated with the NISTmAb reference material. Analytical and Bioanalytical Chemistry 411:24, pages 6487-6496.
Crossref
Crossref
John M. Edwards, Pernille Harris, Jens T. Bukrinski & Alexander P. Golovanov. (2019)
Use of
19
F Differential Labelling for the Simultaneous Detection and Monitoring of Three Individual Proteins in a Serum Environment
. ChemPlusChem 84:5, pages 443-446.
Crossref
Crossref
Yukako Senga, Hiroshi Imamura, Toshihiko Ogura & Shinya Honda. (2019) In-Solution Microscopic Imaging of Fractal Aggregates of a Stressed Therapeutic Antibody. Analytical Chemistry 91:7, pages 4640-4648.
Crossref
Crossref
Qun Zhou & Huawei Qiu. (2019) The Mechanistic Impact of N-Glycosylation on Stability, Pharmacokinetics, and Immunogenicity of Therapeutic Proteins. Journal of Pharmaceutical Sciences 108:4, pages 1366-1377.
Crossref
Crossref
Steffen Dickopf, Matthias E. Lauer, Philippe Ringler, Christian Spick, Peter Kern & Ulrich Brinkmann. (2019) Highly flexible, IgG-shaped, trivalent antibodies effectively target tumor cells and induce T cell-mediated killing. Biological Chemistry 400:3, pages 343-350.
Crossref
Crossref
Shuang Sun, Padma Akkapeddi, Marta C. Marques, Nuria Martínez-Sáez, Vukosava M. Torres, Carlos Cordeiro, Omar Boutureira & Gonçalo J. L. Bernardes. (2019) One-pot stapling of interchain disulfides of antibodies using an isobutylene motif. Organic & Biomolecular Chemistry 17:7, pages 2005-2012.
Crossref
Crossref
Christie E. Delaney, John F. Kelly, Wen Ding & Arsalan S. Haqqani. 2019. Immunoproteomics. Immunoproteomics
153
166
.
Anne S. Strik, Yow-Ming C. Wang, Laura E. Ruff, William Yashar, Bradley T. Messmer & Diane R. Mould. (2018) Individualized Dosing of Therapeutic Monoclonal Antibodies—a Changing Treatment Paradigm?. The AAPS Journal 20:6.
Crossref
Crossref
Stephanie N. Kennedy, Brittany Wilhite, J. Margaret Castellini, Lorrie D. Rea, Thomas B. Kuhn, Andrea Ferrante & Todd M. O'Hara. (2018) Enhanced quantification of serum immunoglobulin G from a non-model wildlife species, the Steller sea lion (Eumetopias jubatus), using a protein A ELISA. Journal of Immunological Methods 462, pages 42-47.
Crossref
Crossref
Na Yang, Qing Tang, Ping Hu & Michael J. Lewis. (2018) Use of In Vitro Systems To Model In Vivo Degradation of Therapeutic Monoclonal Antibodies. Analytical Chemistry 90:13, pages 7896-7902.
Crossref
Crossref
Delphine Vivier, Sai Kiran Sharma & Brian M. Zeglis. (2018) Understanding the in vivo fate of radioimmunoconjugates for nuclear imaging. Journal of Labelled Compounds and Radiopharmaceuticals 61:9, pages 672-692.
Crossref
Crossref
Krzysztof P. Bzymek, James W. Puckett, Cindy Zer, Jun Xie, Yuelong Ma, Jeremy D. King, Leah H. Goodstein, Kendra N. Avery, David Colcher, Gagandeep Singh, David A. Horne & John C. Williams. (2018) Mechanically interlocked functionalization of monoclonal antibodies. Nature Communications 9:1.
Crossref
Crossref
Deni Hardiansyah & Chee Meng Ng. (2018) Two-Pore Minimum Physiologically-based Pharmacokinetic Model to Describe the Disposition of Therapeutic Monoclonal IgG Antibody in Humans. Pharmaceutical Research 35:3.
Crossref
Crossref
Chiuan Herng Leow, Qin Cheng, Katja Fischer & James McCarthy. 2018. Antibody Engineering. Antibody Engineering.
Anna Bootz, Astrid Karbach, Johannes Spindler, Barbara Kropff, Nina Reuter, Heinrich Sticht, Thomas H. Winkler, William J. Britt & Michael Mach. (2017) Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus. PLOS Pathogens 13:8, pages e1006601.
Crossref
Crossref
Paul Declerck & Mourad Farouk Rezk. (2017) The road from development to approval: evaluating the body of evidence to confirm biosimilarity. Rheumatology 56:suppl_4, pages iv4-iv13.
Crossref
Crossref
Till Uhlig & Guro L. Goll. (2017) Reviewing the evidence for biosimilars: key insights, lessons learned and future horizons. Rheumatology 56:suppl_4, pages iv49-iv62.
Crossref
Crossref
Michael A Partridge, Uma Vijayam, Elif Kabuloglu Karayusuf, Enoch Shum, Thanoja Sirimanne, John Garlits, Jihua Chen, Albert Torri & Giane Sumner. (2017) Bridging immunogenicity assays for IgG4 therapeutics: mitigating interference from Fc–Fc interactions. Bioanalysis 9:9, pages 707-717.
Crossref
Crossref
Sushrut Arora, Vikas Saxena & B. Vijayalakshmi Ayyar. (2017) Affinity chromatography: A versatile technique for antibody purification. Methods 116, pages 84-94.
Crossref
Crossref
Bernd Moritz & Jan Olaf Stracke. (2017) Assessment of disulfide and hinge modifications in monoclonal antibodies. ELECTROPHORESIS 38:6, pages 769-785.
Crossref
Crossref
Roy Jefferis. 2017. Biosimilar Drug Product Development. Biosimilar Drug Product Development
109
150
.
Susan Moir & Anthony S. Fauci. (2017)
B‐cell responses to
HIV
infection
. Immunological Reviews 275:1, pages 33-48.
Crossref
Crossref
G.G. Fouda, J. Eudailey, E.L. Kunz, J.D. Amos, B.E. Liebl, J. Himes, F. Boakye-Agyeman, K. Beck, A.J. Michaels, M. Cohen-Wolkowiez, B.F. Haynes, K.A. Reimann & S.R. Permar. (2017) Systemic administration of an HIV-1 broadly neutralizing dimeric IgA yields mucosal secretory IgA and virus neutralization. Mucosal Immunology 10:1, pages 228-237.
Crossref
Crossref
Maria Kristina Parr, Othman Montacir & Houda Montacir. (2016) Physicochemical characterization of biopharmaceuticals. Journal of Pharmaceutical and Biomedical Analysis 130, pages 366-389.
Crossref
Crossref
Ray Bakhtiar. (2016) Antibody drug conjugates. Biotechnology Letters 38:10, pages 1655-1664.
Crossref
Crossref
Saradha Chandrasekhar, Balakrishnan S. Moorthy, Ruichao Xie & Elizabeth M. Topp. (2016) Thiol-Disulfide Exchange in Human Growth Hormone. Pharmaceutical Research 33:6, pages 1370-1382.
Crossref
Crossref
Laura R. Stingaciu, Oxana Ivanova, Michael Ohl, Ralf Biehl & Dieter Richter. (2016) Fast antibody fragment motion: flexible linkers act as entropic spring. Scientific Reports 6:1.
Crossref
Crossref
Yi Wang, Huijuan Li, Mohammed Shameem & Wei Xu. (2016) Development of a sample preparation method for monitoring correct disulfide linkages of monoclonal antibodies by liquid chromatography–mass spectrometry. Analytical Biochemistry 495, pages 21-28.
Crossref
Crossref
Roy Jefferis. (2016) Posttranslational Modifications and the Immunogenicity of Biotherapeutics. Journal of Immunology Research 2016, pages 1-15.
Crossref
Crossref
E. B. Struble, N. Kirschbaum, J. Liu, E. Marszal & M. Shapiro. 2017. Protein Therapeutics. Protein Therapeutics
69
121
.
Neeraj Agrawal & Naresh Chennamsetty. 2015. Developability of Biotherapeutics. Developability of Biotherapeutics
61
84
.
Fabian Higel, Andreas Seidl, Uwe Demelbauer, Margot Viertlboeck-Schudy, Vera Koppenburg, Ulrich Kronthaler, Fritz S?rgel & Wolfgang Frie?. (2015) N-glycan PK Profiling Using a High Sensitivity nanoLCMS Work-Flow with Heavy Stable Isotope Labeled Internal Standard and Application to a Preclinical Study of an IgG1 Biopharmaceutical. Pharmaceutical Research 32:11, pages 3649-3659.
Crossref
Crossref
Olivier Mozziconacci & Christian Schöneich. (2015) Chemical degradation of proteins in the solid state with a focus on photochemical reactions. Advanced Drug Delivery Reviews 93, pages 2-13.
Crossref
Crossref
Matthew Andisik, Lisa DeStefano, Colin Stefan, Meghna Gathani, Kevin Laurino, Vicky CH Lai, Manoj Rajadhyaksha, Albert Torri & Weiping Shao. (2015) Effects of blood processing and sample storage on the stability of biotherapeutics and anti-drug antibodies. Bioanalysis 7:11, pages 1325-1335.
Crossref
Crossref
Sandra Rosskopf, István Gyurján, Regina Soldo, Johana A. Luna-Coronell, Klemens Vierlinger, Christian F. Singer, Christine Rappaport, Nina Pecha & Andreas Weinhaeusel. (2015) The pre-analytical processing of blood samples for detecting biomarkers on protein microarrays. Journal of Immunological Methods 418, pages 39-51.
Crossref
Crossref
Laura K. Hmiel, Kurt A. Brorson & Michael T. BoyneIIII. (2014) Post-translational structural modifications of immunoglobulin G and their effect on biological activity. Analytical and Bioanalytical Chemistry 407:1, pages 79-94.
Crossref
Crossref
Christian Schöneich. 2015. Biobetters. Biobetters
137
151
.
Balakrishnan S. Moorthy, Bo Xie, Ehab M. Moussa, Lavanya K. Iyer, Saradha Chandrasekhar, Jainik P. Panchal & Elizabeth M. Topp. 2015. Biobetters. Biobetters
105
135
.
Michael Siedler, Vineet Kumar, Ravi Chari, Sonal Saluja & Wolfgang Fraunhofer. 2015. Quality by Design for Biopharmaceutical Drug Product Development. Quality by Design for Biopharmaceutical Drug Product Development
61
85
.
Michael P. Hall. (2014) Biotransformation and In Vivo Stability of Protein Biotherapeutics: Impact on Candidate Selection and Pharmacokinetic Profiling. Drug Metabolism and Disposition 42:11, pages 1873-1880.
Crossref
Crossref
Matthias J. Feige & Johannes Buchner. (2014) Principles and engineering of antibody folding and assembly. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1844:11, pages 2024-2031.
Crossref
Crossref
Wendy R Winnall, Matthew D Beasley, Rob J Center, Matthew S Parsons, Ben R Kiefel & Stephen J Kent. (2014) The maturation of antibody technology for the HIV epidemic. Immunology & Cell Biology 92:7, pages 570-577.
Crossref
Crossref
Jayapriya Jayaraman, Jiemin Wu, Molly C. Brunelle, Anna Marie M. Cruz, Deborah S. Goldberg, Brian Lobo, Ambarish Shah & Peter M. Tessier. (2014) Plasmonic measurements of monoclonal antibody self-association using self-interaction nanoparticle spectroscopy. Biotechnology and Bioengineering 111:8, pages 1513-1520.
Crossref
Crossref
Avanish K. Varshney, Xiaobo Wang, Jorge L. Aguilar, Matthew D. Scharff & Bettina C. Fries. (2014) Isotype Switching Increases Efficacy of Antibody Protection against Staphylococcal Enterotoxin B-Induced Lethal Shock and Staphylococcus aureus Sepsis in Mice. mBio 5:3.
Crossref
Crossref
Bertrand Magy, J?r?mie Tollet, Rapha?lle Laterre, Marc Boutry & Catherine Navarre. (2014) Accumulation of secreted antibodies in plant cell cultures varies according to the isotype, host species and culture conditions. Plant Biotechnology Journal 12:4, pages 457-467.
Crossref
Crossref
Giuseppe TridenteGiuseppe Tridente. 2014. Adverse Events with Biomedicines. Adverse Events with Biomedicines
51
63
.
Tran Thi Thuy & Gunnar Thorsén. (2013) Glycosylation Profiling of Therapeutic Antibodies in Serum Samples Using a Microfluidic CD Platform and MALDI-MS. Journal of the American Society for Mass Spectrometry 24:7, pages 1053-1063.
Crossref
Crossref
Dmitrij Hristodorov, Rainer Fischer & Lars Linden. (2012) With or Without Sugar? (A)glycosylation of Therapeutic Antibodies. Molecular Biotechnology 54:3, pages 1056-1068.
Crossref
Crossref
Marcia Federici, Anthony Lubiniecki, Prakash Manikwar & David B. Volkin. (2013) Analytical lessons learned from selected therapeutic protein drug comparability studies. Biologicals 41:3, pages 131-147.
Crossref
Crossref
Shantanu V. Sule, Craig D. Dickinson, Jirong Lu, Chi-Kin Chow & Peter M. Tessier. (2013) Rapid Analysis of Antibody Self-Association in Complex Mixtures Using Immunogold Conjugates. Molecular Pharmaceutics 10:4, pages 1322-1331.
Crossref
Crossref
Dmitrij Hristodorov, Rainer Fischer, Hannah Joerissen, Beate M?ller-Tiemann, Heiner Apeler & Lars Linden. (2012) Generation and Comparative Characterization of Glycosylated and Aglycosylated Human IgG1 Antibodies. Molecular Biotechnology 53:3, pages 326-335.
Crossref
Crossref
Thomas R. Gelzleichter. 2013. Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics. Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics
185
210
.
Melinda Marian & Wolfgang Seghezzi. 2013. Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics. Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics
97
137
.
Sheng Yin, Cinthia V. Pastuskovas, Leslie A. Khawli & John T. Stults. (2012) Characterization of Therapeutic Monoclonal Antibodies Reveals Differences Between In Vitro and In Vivo Time-Course Studies. Pharmaceutical Research 30:1, pages 167-178.
Crossref
Crossref
Matthieu Broussas, Lucile Broyer & Liliane Goetsch. 2013. Glycosylation Engineering of Biopharmaceuticals. Glycosylation Engineering of Biopharmaceuticals
305
317
.
Richard Ludwig, Jacob Bongers, Li Tao, Yunping Huang, Jinmei Fu, Wei Wu, Peiran Liu, Hangtian Song & Reb Russell. 2013. Characterization of Protein Therapeutics using Mass Spectrometry. Characterization of Protein Therapeutics using Mass Spectrometry
207
277
.
Jingjie Mo, Adrienne A. Tymiak & Guodong Chen. 2013. Characterization of Protein Therapeutics using Mass Spectrometry. Characterization of Protein Therapeutics using Mass Spectrometry
163
205
.
Daniela Bumbaca, C. Andrew Boswell, Paul J. Fielder & Leslie A. Khawli. (2012) Physiochemical and Biochemical Factors Influencing the Pharmacokinetics of Antibody Therapeutics. The AAPS Journal 14:3, pages 554-558.
Crossref
Crossref
James T. Heads, Ralph Adams, Lena E. D'Hooghe, Matt J. T. Page, David P. Humphreys, Andrew G. Popplewell, Alastair D. Lawson & Alistair J. Henry. (2012) Relative stabilities of IgG1 and IgG4 Fab domains: Influence of the light–heavy interchain disulfide bond architecture. Protein Science 21:9, pages 1315-1322.
Crossref
Crossref
Shirley J. Peters, C. Mark Smales, Alistair J. Henry, Paul E. Stephens, Shauna West & David P. Humphreys. (2012) Engineering an Improved IgG4 Molecule with Reduced Disulfide Bond Heterogeneity and Increased Fab Domain Thermal Stability. Journal of Biological Chemistry 287:29, pages 24525-24533.
Crossref
Crossref
Xiaotao Duan, Lubna Abuqayyas, Lipeng Dai, Joseph P. Balthasar & Jun Qu. (2012) High-Throughput Method Development for Sensitive, Accurate, and Reproducible Quantification of Therapeutic Monoclonal Antibodies in Tissues Using Orthogonal Array Optimization and Nano Liquid Chromatography/Selected Reaction Monitoring Mass Spectrometry. Analytical Chemistry 84:10, pages 4373-4382.
Crossref
Crossref
Alex Eon‐Duval, Hervé Broly & Ralf Gleixner. (2012) Quality attributes of recombinant therapeutic proteins: An assessment of impact on safety and efficacy as part of a quality by design development approach. Biotechnology Progress 28:3, pages 608-622.
Crossref
Crossref
B. Vijayalakshmi Ayyar, Sushrut Arora, Caroline Murphy & Richard O’Kennedy. (2012) Affinity chromatography as a tool for antibody purification. Methods 56:2, pages 116-129.
Crossref
Crossref
Jeffery S. Russell & A. Dimitrios Colevas. (2012) The Use of Epidermal Growth Factor Receptor Monoclonal Antibodies in Squamous Cell Carcinoma of the Head and Neck. Chemotherapy Research and Practice 2012, pages 1-13.
Crossref
Crossref
Timothy M. Lauer, Neeraj J. Agrawal, Naresh Chennamsetty, Kamal Egodage, Bernhard Helk & Bernhardt L. Trout. (2012) Developability Index: A Rapid In Silico Tool for the Screening of Antibody Aggregation Propensity. Journal of Pharmaceutical Sciences 101:1, pages 102-115.
Crossref
Crossref
Ada Triguero, Gleysin Cabrera, Meilyn Rodríguez, Jeny Soto, Yasser Zamora, Marlene Pérez, Mark R. Wormald & José A. Cremata. (2011)
Differential N‐glycosylation of a monoclonal antibody expressed in tobacco leaves with and without endoplasmic reticulum retention signal apparently induces similar
in vivo
stability in mice
. Plant Biotechnology Journal 9:9, pages 1120-1130.
Crossref
Crossref
Yi Wang, Qiaozhen Lu, Shiaw-Lin Wu, Barry L. Karger & William S. Hancock. (2011) Characterization and Comparison of Disulfide Linkages and Scrambling Patterns in Therapeutic Monoclonal Antibodies: Using LC-MS with Electron Transfer Dissociation. Analytical Chemistry 83:8, pages 3133-3140.
Crossref
Crossref
Patrick G Swann & Marjorie A Shapiro. (2011) Regulatory considerations for development of bioanalytical assays for biotechnology products. Bioanalysis 3:6, pages 597-603.
Crossref
Crossref
Jean W Lee, Yow-Ming Wang, Michael Moxness & Binodh DeSilva. (2011) Bioanalytical considerations in the comparability assessment of biotherapeutics. Bioanalysis 3:6, pages 613-622.
Crossref
Crossref
Sanchayita Ghose, Justin Ladwig & Martin Allen. (2011) Comparison of the chromatographic properties of IgG1 and IgG2 antibody subclasses. Biotechnology and Applied Biochemistry 57:3, pages 111-116.
Crossref
Crossref