Autophagy, Volume 14, Issue 4 (2018)

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Autophagy, Volume 14, Issue 4 (2018)

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Editor's Corner

Editorial
A PINK1-mediated mitophagy pathway decides the fate of tumors—to be benign or malignant?
Hui Qian, Xiaojuan Chao & Wen-Xing Ding
Pages: 563-566
Published online: 21 Feb 2018
AbstractforA PINK1-mediated mitophagy pathway decides the fate of tumors—to be benign or malignant? | Full Text | References | PDF (295.9 KB)
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Brief Report - Basic Science

Brief Report
The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts
Andreas Struchtrup, Antonia Wiegering, Björn Stork, Ulrich Rüther & Christoph Gerhardt
Pages: 567-583
Published online: 21 Feb 2018
AbstractforThe ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts | Full Text | References | PDF (1.8 MB) | Supplemental
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Research Papers - Basic Science

Article
ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction
Ji-Man Park, Minchul Seo, Chang Hwa Jung, Douglas Grunwald, Matthew Stone, Neil Michael Otto, Erik Toso, Yeseul Ahn, Michael Kyba, Timothy J. Griffin, LeeAnn Higgins & Do-Hyung Kim
Pages: 584-597
Published online: 21 Feb 2018
AbstractforULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
iTRAQ-based proteomics analysis of autophagy-mediated immune responses against the vascular fungal pathogen Verticillium dahliae in Arabidopsis
Fu-Xin Wang, Yuan-Ming Luo, Zi-Qin Ye, Xue Cao, Jing-Nan Liang, Qian Wang, Yao Wu, Jia-He Wu, Hai-Yun Wang, Min Zhang, Huan-Qing Cheng & Gui-Xian Xia
Pages: 598-618
Published online: 21 Feb 2018
AbstractforiTRAQ-based proteomics analysis of autophagy-mediated immune responses against the vascular fungal pathogen Verticillium dahliae in Arabidopsis | Full Text | References | PDF (3.2 MB) | Supplemental
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Research Paper - Basic Science

Article
Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers
Mireia Nàger, Marta C. Sallán, Anna Visa, Charumathi Pushparaj, Maria Santacana, Anna Macià, Andrée Yeramian, Carles Cantí & Judit Herreros
Pages: 619-636
Published online: 21 Feb 2018
AbstractforInhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers | Full Text | References | PDF (2.1 MB) | Supplemental
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Article
RAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells
Margie N. Sutton, Hailing Yang, Gilbert Y. Huang, Caroline Fu, Michael Pontikos, Yan Wang, Weiqun Mao, Lan Pang, Maojie Yang, Jinsong Liu, Jan Parker-Thornburg, Zhen Lu & Robert C. Bast Jr
Pages: 637-653
Published online: 21 Mar 2018
AbstractforRAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells | Full Text | References | PDF (2.3 MB) | Supplemental
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Article
NUPR1 maintains autolysosomal efflux by activating SNAP25 transcription in cancer cells
Yanchao Mu, Xiaojie Yan, Ding Li, Dan Zhao, Lingling Wang, Xiaoyang Wang, Dan Gao, Jie Yang, Hua Zhang, Yanzhe Li, Yanan Sun, Yiliang Wei, Zhenfa Zhang, Xinzhong Chang, Zhi Yao, Shanshan Tian, Kai Zhang, Lance S. Terada, Zhenyi Ma & Zhe Liu
Pages: 654-670
Published online: 31 Dec 2017
AbstractforNUPR1 maintains autolysosomal efflux by activating SNAP25 transcription in cancer cells | Full Text | References | PDF (2.1 MB) | Supplemental
  • 3902 Views
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Article
Regulation of glycolytic metabolism by autophagy in liver cancer involves selective autophagic degradation of HK2 (hexokinase 2)
Lin Jiao, Hai-Liang Zhang, Dan-Dan Li, Ke-Li Yang, Jun Tang, Xuan Li, Jiao Ji, Yan Yu, Rui-Yan Wu, Senthilkumar Ravichandran, Jian-Jun Liu, Gong-Kan Feng, Min-Shan Chen, Yi-Xin Zeng, Rong Deng & Xiao-Feng Zhu
Pages: 671-684
Published online: 17 Dec 2017
AbstractforRegulation of glycolytic metabolism by autophagy in liver cancer involves selective autophagic degradation of HK2 (hexokinase 2) | Full Text | References | PDF (1.4 MB) | Supplemental
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Research Papers - Basic Science

Article
AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells
Zhenhong Ni, Jintao He, Yaran Wu, Changjiang Hu, Xufang Dai, Xiaojing Yan, Bo Li, Xinzhe Li, Haojun Xiong, Yuming Li, Song Li, Liang Xu, Yongsheng Li, Jiqin Lian & Fengtian He
Pages: 685-701
Published online: 29 Jan 2018
AbstractforAKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells | Full Text | References | PDF (1.5 MB) | Supplemental
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Article
Autophagy contributes to sulfonylurea herbicide tolerance via GCN2-independent regulation of amino acid homeostasis
Lun Zhao, Li Deng, Qing Zhang, Xue Jing, Meng Ma, Bin Yi, Jing Wen, Chaozhi Ma, Jinxing Tu, Tingdong Fu & Jinxiong Shen
Pages: 702-714
Published online: 29 Jan 2018
AbstractforAutophagy contributes to sulfonylurea herbicide tolerance via GCN2-independent regulation of amino acid homeostasis | Full Text | References | PDF (1.5 MB) | Supplemental
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Autophagic Punctum

Article Commentary
Mitophagy and hepatic cancer stem cells
Jiyoung Lee, Kai Liu, Bangyan Stiles & Jing-hsiung James Ou
Pages: 715-716
Published online: 21 Feb 2018
CitationforMitophagy and hepatic cancer stem cells | Full Text | PDF (372.7 KB)
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Commentary

Article Commentary
Cholesterol and multilamellar bodies: Lysosomal dysfunction in GBA-Parkinson disease
Patricia García-Sanz, Lorena Orgaz, José M. Fuentes, Carlos Vicario & Rosario Moratalla
Pages: 717-718
Published online: 11 Mar 2018
AbstractforCholesterol and multilamellar bodies: Lysosomal dysfunction in GBA-Parkinson disease | Full Text | PDF (482.6 KB)
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Article Commentary
Secretory autophagy of lysozyme in Paneth cells
Shai Bel & Lora V. Hooper
Pages: 719-721
Published online: 08 Mar 2018
AbstractforSecretory autophagy of lysozyme in Paneth cells | Full Text | PDF (539.1 KB)
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Article Commentary
Karyoptosis: A novel type of cell death caused by chronic autophagy inhibition
Olga Baron & Manolis Fanto
Pages: 722-723
Published online: 13 Mar 2018
AbstractforKaryoptosis: A novel type of cell death caused by chronic autophagy inhibition | Full Text | PDF (386.8 KB)
  • 1888 Views
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Article Commentary
TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis
Trent D. Evans, Se-Jin Jeong, Xiangyu Zhang, Ismail Sergin & Babak Razani
Pages: 724-726
Published online: 08 Mar 2018
AbstractforTFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis | Full Text | PDF (448.1 KB)
  • 7302 Views
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Article Commentary
The small GTPase RAB37 functions as an organizer for autophagosome biogenesis
Ying Song, Dantong Shang, Hanhua Cheng & Rongjia Zhou
Pages: 727-729
Published online: 13 Mar 2018
AbstractforThe small GTPase RAB37 functions as an organizer for autophagosome biogenesis | Full Text | PDF (406.4 KB)
  • 1286 Views
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Article Commentary
Targeting autophagy blocks melanoma growth by bringing natural killer cells to the tumor battlefield
Muhammad Zaeem Noman, Guy Berchem & Bassam Janji
Pages: 730-732
Published online: 11 Mar 2018
AbstractforTargeting autophagy blocks melanoma growth by bringing natural killer cells to the tumor battlefield | Full Text | PDF (468.7 KB)
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Views and Commentaries

Article
Unraveling the role of motoneuron autophagy in ALS
Vicente Valenzuela, Melissa Nassif & Claudio Hetz
Pages: 733-737
Published online: 13 Mar 2018
AbstractforUnraveling the role of motoneuron autophagy in ALS | Full Text | References | PDF (490.7 KB)
  • 2762 Views
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