OncoImmunology, Volume 3, Issue 4 (2014)

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OncoImmunology, Volume 3, Issue 4 (2014)

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Editorial

Editorial
Meta-analysis and metagenes
CXCL-13-driven signature as a robust marker of intratumoral immune response and predictor of breast cancer chemotherapeutic outcome
Davide Bedognetti, Ena Wang & Francesco M Marincola
Article: e28727
Published online: 09 Apr 2014
First Page PreviewforMeta-analysis and metagenes | Full Text | References | PDF (566.6 KB)
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Original Research

Article
Electrochemotherapy with bleomycin induces hallmarks of immunogenic cell death in murine colon cancer cells
Christophe Y Calvet, Delphine Famin, Franck M André & Lluis M Mir
Article: e28131
Published online: 15 Apr 2014
AbstractforElectrochemotherapy with bleomycin induces hallmarks of immunogenic cell death in murine colon cancer cells | Full Text | References | PDF (902.6 KB)
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Article
Screening of novel immunogenic cell death inducers within the NCI Mechanistic Diversity Set
Abdul Qader Sukkurwala, Sandy Adjemian, Laura Senovilla, Mickaël Michaud, Sabrina Spaggiari, Erika Vacchelli, Elisa Elena Baracco, Lorenzo Galluzzi, Laurence Zitvogel, Oliver Kepp & Guido Kroemer
Article: e28473
Published online: 16 Apr 2014
AbstractforScreening of novel immunogenic cell death inducers within the NCI Mechanistic Diversity Set | Full Text | References | PDF (3.8 MB) | Supplemental
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Article
Radiation fosters dose-dependent and chemotherapy-induced immunogenic cell death
Encouse B Golden, Derek Frances, Ilenia Pellicciotta, Sandra Demaria, Mary Helen Barcellos-Hoff & Silvia C Formenti
Article: e28518
Published online: 25 Apr 2014
AbstractforRadiation fosters dose-dependent and chemotherapy-induced immunogenic cell death | Full Text | References | PDF (2.1 MB) | Supplemental
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Review

Review Article
Trial Watch
DNA vaccines for cancer therapy
Jonathan Pol, Norma Bloy, Florine Obrist, Alexander Eggermont, Jérôme Galon, Wolf Hervé Fridman, Isabelle Cremer, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi
Article: e28185
Published online: 01 Apr 2014
AbstractforTrial Watch | Full Text | References | PDF (304.6 KB)
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Review Article
Myeloid-derived cells are key targets of tumor immunotherapy
José Medina-Echeverz, Fernando Aranda & Pedro Berraondo
Article: e28398
Published online: 15 Apr 2014
AbstractforMyeloid-derived cells are key targets of tumor immunotherapy | Full Text | References | PDF (1.2 MB)
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Review Article
Secretory pathways generating immunosuppressive NKG2D ligands: New targets for therapeutic intervention
Aroa Baragaño Raneros, Beatriz Suarez Álvarez & Carlos López Larrea
Article: e28497
Published online: 25 Apr 2014
AbstractforSecretory pathways generating immunosuppressive NKG2D ligands: New targets for therapeutic intervention | PDF (1.1 MB)
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Point of View

Are natural killer cells superior CAR drivers?
Hans Klingemann
Article: e28147
Published online: 15 Apr 2014
AbstractforAre natural killer cells superior CAR drivers? | Full Text | References | PDF (190 KB)
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Iron-induced parafibrin formation in tumors fosters immune evasion
Boguslaw Lipinski
Article: e28539
Published online: 25 Apr 2014
AbstractforIron-induced parafibrin formation in tumors fosters immune evasion | Full Text | References | PDF (986.9 KB)
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Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo
Enhanced gene transfer and adjuvant activity
Christophe Y Calvet, Franck M André & Lluis M Mir
Article: e28540
Published online: 29 Apr 2014
AbstractforDual therapeutic benefit of electroporation-mediated DNA vaccination in vivo | Full Text | References | PDF (807.4 KB)
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Author's View

Sleep apnea awakens cancer
A unifying immunological hypothesis
David Gozal, Isaac Almendros & Fahed Hakim
Article: e28326
Published online: 27 Mar 2014
AbstractforSleep apnea awakens cancer | Full Text | References | PDF (806.9 KB)
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Lymphocyte-derived interleukin-17A adds another brick in the wall of inflammation-induced breast carcinogenesis
Jérémy Bastid, Nathalie Bonnefoy, Jean-François Eliaou & Armand Bensussan
Article: e28273
Published online: 27 Mar 2014
AbstractforLymphocyte-derived interleukin-17A adds another brick in the wall of inflammation-induced breast carcinogenesis | Full Text | References | PDF (845.5 KB)
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Dual targeting of CD137 co-stimulatory and PD-1 co-inhibitory molecules for ovarian cancer immunotherapy
Huafeng Wei, Likun Zhao, Ingegerd Hellstrom, Karl Erik Hellstrom & Yajun Guo
Article: e28248
Published online: 28 Mar 2014
AbstractforDual targeting of CD137 co-stimulatory and PD-1 co-inhibitory molecules for ovarian cancer immunotherapy | Full Text | References | PDF (721.5 KB)
  • 1638 Views
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Tumor vascularity in ovarian cancer
T cells need breathing room
David Neilson, Sarah MacPherson, Katelin N Townsend & Julian J Lum
Article: e28272
Published online: 08 Apr 2014
AbstractforTumor vascularity in ovarian cancer | Full Text | References | PDF (766.5 KB)
  • 556 Views
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Immune checkpoints
A therapeutic target in triple negative breast cancer
Akhil Chawla, Anne V Philips, Gheath Alatrash & Elizabeth Mittendorf
Article: e28325
Published online: 08 Apr 2014
AbstractforImmune checkpoints | Full Text | References | PDF (734 KB)
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KLRG1+ natural killer cells protect against pulmonary metastatic disease by immunosurveillance
Philipp Renner, Jordi Rovira, Christoph Klein, Hans-Jürgen Schlitt, Edward K Geissler & Alexander Kroemer
Article: e28328
Published online: 08 Apr 2014
AbstractforKLRG1+ natural killer cells protect against pulmonary metastatic disease by immunosurveillance | Full Text | References | PDF (877 KB)
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Natural killer T cell strategies to combat Epstein–Barr virus infection
John J Priatel, Brian K Chung, Kevin Tsai & Rusung Tan
Article: e28329
Published online: 09 Apr 2014
AbstractforNatural killer T cell strategies to combat Epstein–Barr virus infection | Full Text | References | PDF (831.3 KB)
  • 937 Views
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The ELR+CXCL chemokines and their receptors CXCR1/CXCR2
A signaling axis and new target for the treatment of renal cell carcinoma
Sandy Giuliano, Mélanie Guyot, Renaud Grépin & Gilles Pagès
Article: e28399
Published online: 09 Apr 2014
AbstractforThe ELR+CXCL chemokines and their receptors CXCR1/CXCR2 | Full Text | References | PDF (739.7 KB)
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The transmembrane channel-like protein family and human papillomaviruses
Insights into epidermodysplasia verruciformis and progression to squamous cell carcinoma
Jaime S Horton & Alexander J Stokes
Article: e28288
Published online: 15 Apr 2014
AbstractforThe transmembrane channel-like protein family and human papillomaviruses | Full Text | References | PDF (850.9 KB)
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Rethinking the role of myeloid-derived suppressor cells in adoptive T-cell therapy for cancer
Ainhoa Arina
Article: e28464
Published online: 15 Apr 2014
AbstractforRethinking the role of myeloid-derived suppressor cells in adoptive T-cell therapy for cancer | Full Text | References | PDF (801.2 KB)
  • 386 Views
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Immune response markers in sentinel nodes may predict melanoma progression
Monica Rodolfo, Chiara Castelli & Licia Rivoltini
Article: e28498
Published online: 15 Apr 2014
AbstractforImmune response markers in sentinel nodes may predict melanoma progression | Full Text | References | PDF (884.5 KB)
  • 554 Views
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Synergistic antitumor effects of a TGFβ inhibitor and cyclophosphamide
Xin Chen, Lalage M Wakefield & Joost J Oppenheim
Article: e28247
Published online: 16 Apr 2014
AbstractforSynergistic antitumor effects of a TGFβ inhibitor and cyclophosphamide | Full Text | References | PDF (1 MB)
  • 559 Views
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Engineered chimeric antigen receptor-expressing T cells for the treatment of pancreatic ductal adenocarcinoma
Gregory L Beatty
Article: e28327
Published online: 17 Apr 2014
AbstractforEngineered chimeric antigen receptor-expressing T cells for the treatment of pancreatic ductal adenocarcinoma | Full Text | References | PDF (911.7 KB)
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Macrophages in the liver prevent metastasis by efficiently eliminating circulating tumor cells after monoclonal antibody immunotherapy
Nuray Gül, Liane Babes, Paul Kubes & Marjolein van Egmond
Article: e28441
Published online: 17 Apr 2014
AbstractforMacrophages in the liver prevent metastasis by efficiently eliminating circulating tumor cells after monoclonal antibody immunotherapy | PDF (237 KB)
  • 415 Views
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Sarcoma response to targeted therapy dynamically polarizes tumor-associated macrophages
Michael J Cavnar & Ronald P DeMatteo
Article: e28463
Published online: 17 Apr 2014
AbstractforSarcoma response to targeted therapy dynamically polarizes tumor-associated macrophages | Full Text | References | PDF (728 KB)
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Radiation and anti-PD-L1 antibody combinatorial therapy induces T cell-mediated depletion of myeloid-derived suppressor cells and tumor regression
liufu deng, hua liang, byron Burnette, ralph weicheslbaum & Yang-Xin Fu
Article: e28499
Published online: 17 Apr 2014
AbstractforRadiation and anti-PD-L1 antibody combinatorial therapy induces T cell-mediated depletion of myeloid-derived suppressor cells and tumor regression | PDF (280.7 KB)
  • 835 Views
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Discovering cancer immunotherapy targets in vivo
Penghui Zhou & Kai W Wucherpfennig
Article: e28500
Published online: 17 Apr 2014
AbstractforDiscovering cancer immunotherapy targets in vivo | Full Text | References | PDF (1.4 MB)
  • 980 Views
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The heat shock protein-CD91 pathway mediates tumor immunosurveillance
Yu Jerry Zhou & Robert Julian Binder
Article: e28222
Published online: 25 Apr 2014
AbstractforThe heat shock protein-CD91 pathway mediates tumor immunosurveillance | Full Text | References | PDF (1.7 MB)
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Smac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells
Shawn T Beug, Eric C LaCasse & Robert G Korneluk
Article: e28541
Published online: 29 Apr 2014
AbstractforSmac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells | Full Text | References | PDF (165.1 KB)
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