Nucleosides, Nucleotides & Nucleic Acids, Volume 26, Issue 8-9 (2007)

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Nucleosides, Nucleotides & Nucleic Acids, Volume 26, Issue 8-9 (2007)

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Original Articles

Article
Synthesis of Fluorinated Indoles as RNA Analogues
Jelena Božilović & Joachim W. Engels
Pages: 869-871
Published online: 10 Dec 2007
AbstractforSynthesis of Fluorinated Indoles as RNA Analogues | Full Text | References | PDF (162.3 KB)
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Article
Different Strategies for the Synthesis of 2′-O-Aminoethyl Adenosine Building Blocks
Dalibor Odadzic & Joachim W. Engels
Pages: 873-877
Published online: 10 Dec 2007
AbstractforDifferent Strategies for the Synthesis of 2′-O-Aminoethyl Adenosine Building Blocks | Full Text | References | PDF (227.1 KB)
  • 86 Views
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Article
A Phenanthrene Modified RNA Hairpin
Ivan Trkulja, Alfred Stutz & Robert Häner
Pages: 879-882
Published online: 10 Dec 2007
AbstractforA Phenanthrene Modified RNA Hairpin | Full Text | References | PDF (118 KB)
  • 65 Views
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Article
Aldehydic Oligonucleotide: A Key Intermediate for the Preparation of Oligonucleotide Conjugates Through Oxime Bond Formation
N. Spinelli, Y. Singh, E. Defrancq & P. Dumy
Pages: 883-887
Published online: 10 Dec 2007
AbstractforAldehydic Oligonucleotide: A Key Intermediate for the Preparation of Oligonucleotide Conjugates Through Oxime Bond Formation | Full Text | References | PDF (149.3 KB)
  • 76 Views
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Article
Microwave-assisted Ribosylation of modified heterocyclic bases by Vorbrüggen method
Nadja V. Nikolaus, Jelena Božilović & Joachim W. Engels
Pages: 889-892
Published online: 10 Dec 2007
AbstractforMicrowave-assisted Ribosylation of modified heterocyclic bases by Vorbrüggen method | Full Text | References | PDF (82.5 KB)
  • 137 Views
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Article
Acid-Mediated Cleavage oF Oligonucleotide P3′ → N5′ Phosphoramidates Triggered by Sequence-Specific Triplex Formation
Satoshi Obika, Masaharu Tomizu, Yoshinori Negoro, Tomohisa Osaki, Ayako Orita, Yuji Ueyama, Osamu Nakagawa & Takeshi Imanishi
Pages: 893-896
Published online: 10 Dec 2007
AbstractforAcid-Mediated Cleavage oF Oligonucleotide P3′ → N5′ Phosphoramidates Triggered by Sequence-Specific Triplex Formation | Full Text | References | PDF (198.1 KB)
  • 144 Views
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Article
5′-Carbamoylphosphonyl-[6-3H]-AZT as a Tool for Studying Metabolic Transformations of the Nonradioactive Counterpart, an Inhibitor of HIV Replication
Dmitry V. Yanvarev, Elena A. Shirokova, Maria V. Astapova, Vyacheslav I. Shram, Marina K. Kukhanova & Yury S. Skoblov
Pages: 897-900
Published online: 10 Dec 2007
Abstractfor5′-Carbamoylphosphonyl-[6-3H]-AZT as a Tool for Studying Metabolic Transformations of the Nonradioactive Counterpart, an Inhibitor of HIV Replication | Full Text | References | PDF (61.5 KB)
  • 37 Views
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Article
DNA Containing Non-Nucleosidic Phenanthrene Building Blocks with Asymmetrical Linkers
Simon M. Langenegger, Vladimir L. Malinovskii, Daniel Wenger, Sarah Werder & Robert Häner
Pages: 901-903
Published online: 10 Dec 2007
AbstractforDNA Containing Non-Nucleosidic Phenanthrene Building Blocks with Asymmetrical Linkers | Full Text | References | PDF (167.5 KB)
  • 53 Views
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Article
An Enzymatic Transglycosylation of Purine Bases
Jarkko Roivainen, Tatiana Elizarova, Seppo Lapinjoki, Igor A. Mikhailopulo, Roman S. Esipov & Anatoly I. Miroshnikov
Pages: 905-909
Published online: 10 Dec 2007
AbstractforAn Enzymatic Transglycosylation of Purine Bases | Full Text | References | PDF (334.7 KB)
  • 160 Views
  • 13 CrossRef citations
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Article
Design, Enantiopure Synthesis, and Biological Evaluation of Novel ISO-D-2′,3′-Dideoxy-3′-Fluorothianucleoside Derivatives as a bioisostere of Lamivudine
Kyung Ran Kim, Ah-Young Park, Hyung Ryong Moon, Moon Woo Chun & Lak Shin Jeong
Pages: 911-915
Published online: 10 Dec 2007
AbstractforDesign, Enantiopure Synthesis, and Biological Evaluation of Novel ISO-D-2′,3′-Dideoxy-3′-Fluorothianucleoside Derivatives as a bioisostere of Lamivudine | Full Text | References | PDF (133.6 KB)
  • 120 Views
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Article
New Analogs of Acyclovir Substituted at the Side Chain
Zofia Jahnz-Wechmann, Jerzy Boryski, Kunisuke Izawa, Tomoyuki Onishi, Johan Neyts & Erik De Clercq
Pages: 917-920
Published online: 10 Dec 2007
AbstractforNew Analogs of Acyclovir Substituted at the Side Chain | Full Text | References | PDF (138.7 KB)
  • 84 Views
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Article
Synthesis of Anthraquinone Oligonucleotides for Triplex Stabilization
Zhengyun Zhao, Guomei Peng, Jan Michels, Keith R. Fox & Tom Brown
Pages: 921-925
Published online: 10 Dec 2007
AbstractforSynthesis of Anthraquinone Oligonucleotides for Triplex Stabilization | Full Text | References | PDF (181.7 KB)
  • 187 Views
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Article
Clip-Phen Conjugates for the Specific Cleavage of Nucleic Acids
Alain Laurent, Michael Wright, Ali Laayoun, Bernard Meunier, Ludivine Tissot & Marguerite Pitie
Pages: 927-930
Published online: 10 Dec 2007
AbstractforClip-Phen Conjugates for the Specific Cleavage of Nucleic Acids | Full Text | References | PDF (501.3 KB)
  • 134 Views
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Article
OligoPrep PVA Support for Oligonucleotide Synthesis in Columns on a Scale up to 10 μ mol
Sheena Aitken & Emma Anderson
Pages: 931-934
Published online: 10 Dec 2007
AbstractforOligoPrep PVA Support for Oligonucleotide Synthesis in Columns on a Scale up to 10 μ mol | Full Text | References | PDF (217.6 KB)
  • 87 Views
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Article
A New and Short Convergent Synthetic Strategy to Carbocyclic Nucleosides
Bastian Reichardt & Chris Meier
Pages: 935-937
Published online: 10 Dec 2007
AbstractforA New and Short Convergent Synthetic Strategy to Carbocyclic Nucleosides | Full Text | References | PDF (80.8 KB)
  • 146 Views
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Article
Oligonucleotide Charge Reversal: 2′-O-Lysylaminohexyl Modified Oligonucleotides
Johannes Winkler & Christian R. Noe
Pages: 939-942
Published online: 10 Dec 2007
AbstractforOligonucleotide Charge Reversal: 2′-O-Lysylaminohexyl Modified Oligonucleotides | Full Text | References | PDF (500.1 KB)
  • 85 Views
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Article
Asymmetric Synthesis of Apio Fluoroneplanocin a Analogs as Potential AdoHcy Hydrolase Inhibitor
Ah-Young Park, Hyung Ryong Moon, Kyung Ran Kim, Jin-Ah Kang, Moon Woo Chun & Lak Shin Jeong
Pages: 943-947
Published online: 10 Dec 2007
AbstractforAsymmetric Synthesis of Apio Fluoroneplanocin a Analogs as Potential AdoHcy Hydrolase Inhibitor | Full Text | References | PDF (128.3 KB)
  • 107 Views
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Article
Hairpin Mimics with Phenanthroline- and Bipyridine-Derived Linkers
Gapian Bianké & Robert Häner
Pages: 949-952
Published online: 10 Dec 2007
AbstractforHairpin Mimics with Phenanthroline- and Bipyridine-Derived Linkers | Full Text | References | PDF (148.5 KB)
  • 121 Views
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Article
Inhibition of HIV-1 Replication in Macrophages by Red Blood Cell-Mediated Delivery of a Heterodinucleotide of Lamivudine and Tenofovir
P. Franchetti, L. Cappellacci, R. Petrelli, P. Vita, M. Grifantini, L. Rossi, F. Pierigé, S. Serafini, M. Magnani, E. Balestra & C.-F. Perno
Pages: 953-957
Published online: 10 Dec 2007
AbstractforInhibition of HIV-1 Replication in Macrophages by Red Blood Cell-Mediated Delivery of a Heterodinucleotide of Lamivudine and Tenofovir | Full Text | References | PDF (115.8 KB)
  • 96 Views
  • 6 CrossRef citations
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Article
A General Route to D- and L-Six-Membered Nucleoside Analogues
Annalisa Guaragna, Daniele D'Alonzo, Mauro De Nisco, Silvana Pedatella & Giovanni Palumbo
Pages: 959-962
Published online: 10 Dec 2007
AbstractforA General Route to D- and L-Six-Membered Nucleoside Analogues | Full Text | References | PDF (149.5 KB)
  • 64 Views
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Article
New developments in the synthesis of oligonucleotide-peptide conjugates
Cecilia Portela, José Luis Mascareñas, Fernando Albericio, Stefania Mazzini, Clara Caminal, Roger Ramos, Sandra M. Ocampo & Ramon Eritja
Pages: 963-967
Published online: 10 Dec 2007
AbstractforNew developments in the synthesis of oligonucleotide-peptide conjugates | Full Text | References | PDF (162.1 KB)
  • 120 Views
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Article
Kinetics of Binding of Multisubstrate Analogue Inhibitor (2-Amino-9-[2-(Phosphonomethoxy)Ethyl]-6-Sulfanylpurine) with Trimeric Purine Nucleoside Phosphorylase
Jan Antosiewicz, Beata Wielgus-Kutrowska, Maciej Długosz, Antonin Holy & Agnieszka Bzowska
Pages: 969-974
Published online: 10 Dec 2007
AbstractforKinetics of Binding of Multisubstrate Analogue Inhibitor (2-Amino-9-[2-(Phosphonomethoxy)Ethyl]-6-Sulfanylpurine) with Trimeric Purine Nucleoside Phosphorylase | Full Text | References | PDF (684.6 KB)
  • 36 Views
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Article
Synthesis of Enantiopure Pseudo-l-Vinylcyclopropyl Nucleosides Bearing Quaternary Carbon as Potential Anti-Herpesvirus Agent
Hyung Ryong Moon, Ah-Young Park, Kyung Ran Kim, Moon Woo Chun & Lak Shin Jeong
Pages: 975-978
Published online: 10 Dec 2007
AbstractforSynthesis of Enantiopure Pseudo-l-Vinylcyclopropyl Nucleosides Bearing Quaternary Carbon as Potential Anti-Herpesvirus Agent | Full Text | References | PDF (120.9 KB)
  • 120 Views
  • 3 CrossRef citations
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Article
Triplex Formation Using Oligonucleotide Clamps Carrying 8-Aminopurines
Anna Aviñó, Marta G. Grimau, Margarita Alvira, Ramon Eritja, Raimundo Gargallo, Modesto Orozco & Carlos González
Pages: 979-983
Published online: 10 Dec 2007
AbstractforTriplex Formation Using Oligonucleotide Clamps Carrying 8-Aminopurines | Full Text | References | PDF (157.9 KB)
  • 71 Views
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Article
Synthesis of 2′,3′-Dideoxyinosine via Radical Deoxygenation
Takayoshi Torii, Kunisuke Izawa, Dae Hyan Cho & Doo Ok Jang
Pages: 985-988
Published online: 10 Dec 2007
AbstractforSynthesis of 2′,3′-Dideoxyinosine via Radical Deoxygenation | Full Text | References | PDF (149.9 KB)
  • 165 Views
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Article
Inhibitory Properties of Nucleotides with Difluoromethylenephosphonic Acid as a Phosphate Mimic versus Calf Spleen Purine Nucleoside Phosphorylase and Effect of These Analogues on the Viability of Human Blood Lymphocytes
Ljubica Glavaš-Obrovac, Mirjana Suver, Sadao Hikishima, Tsutomu Yokomatsu & Agnieszka Bzowska
Pages: 989-993
Published online: 10 Dec 2007
AbstractforInhibitory Properties of Nucleotides with Difluoromethylenephosphonic Acid as a Phosphate Mimic versus Calf Spleen Purine Nucleoside Phosphorylase and Effect of These Analogues on the Viability of Human Blood Lymphocytes | Full Text | References | PDF (152.3 KB)
  • 49 Views
  • 3 CrossRef citations
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Article
Nucleolipids as Potential Organogelators
Helmut Rosemeyer, Eva-Maria Stürenberg & Piet Herdewijn
Pages: 995-999
Published online: 10 Dec 2007
AbstractforNucleolipids as Potential Organogelators | Full Text | References | PDF (563.2 KB)
  • 127 Views
  • 5 CrossRef citations
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Article
Asymmetric Synthesis of Novel Pseudo-d-Vinylcyclopropyl Nucleosides Bearing Quaternary Carbon as Potential Anti-Herpesvirus Agent
Ah-Young Park, Hyung Ryong Moon, Kyung Ran Kim, Moon Woo Chun & Lak Shin Jeong
Pages: 1001-1004
Published online: 10 Dec 2007
AbstractforAsymmetric Synthesis of Novel Pseudo-d-Vinylcyclopropyl Nucleosides Bearing Quaternary Carbon as Potential Anti-Herpesvirus Agent | Full Text | References | PDF (114.7 KB)
  • 89 Views
  • 2 CrossRef citations
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Article
Photoinduced Crosslinking of Double-helical DNA by Psoralen Covalently Linked to a Triple Helix-forming Oligonucleotide under Near-physiological Conditions
Hong Li, Victoria J. Broughton-Head, Keith R. Fox & Tom Brown
Pages: 1005-1009
Published online: 10 Dec 2007
AbstractforPhotoinduced Crosslinking of Double-helical DNA by Psoralen Covalently Linked to a Triple Helix-forming Oligonucleotide under Near-physiological Conditions | Full Text | References | PDF (156.4 KB)
  • 110 Views
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Article
Stereoselective Synthesis of 1′-Functionalized-4′-Thionucleosides
Lak Shin Jeong, Prashantha Gunaga, Hea Ok Kim, Dilip K. Tosh, Hyuk Woo Lee, Seung Ah Choe, Hyung Ryong Moon, Zhan-Guo Gao, Kenneth A. Jacobson & Moon Woo Chun
Pages: 1011-1014
Published online: 10 Dec 2007
AbstractforStereoselective Synthesis of 1′-Functionalized-4′-Thionucleosides | Full Text | References | PDF (135.3 KB)
  • 103 Views
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Article
O2,1′-Anhydro-(β -D-Psicofuranosyl)Thymine and 1-(1′,4′-O-Anhydro-β -D-Psicofuranosyl)Thymine: The Crystal Structures Versus the 1H NMR and AB Initio Data
Jarkko Roivainen, Igor A. Mikhailopulo, Henning Eickmeier & Hans Reuter
Pages: 1015-1019
Published online: 10 Dec 2007
AbstractforO2,1′-Anhydro-(β -D-Psicofuranosyl)Thymine and 1-(1′,4′-O-Anhydro-β -D-Psicofuranosyl)Thymine: The Crystal Structures Versus the 1H NMR and AB Initio Data | Full Text | References | PDF (623.7 KB)
  • 35 Views
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Article
Asymmetric Synthesis of Cyclopropyl-fused 2′-C-Methylcarbanucleosides as Potential Anti-HCV Agents
Lak Shin Jeong, Jeong A. Lee, Hea Ok Kim, Dilip K. Tosh, Hyung Ryong Moon, Seung-Jin Lee, Kang Man Lee, Yhun Y. Sheen & Moon Woo Chun
Pages: 1021-1024
Published online: 10 Dec 2007
AbstractforAsymmetric Synthesis of Cyclopropyl-fused 2′-C-Methylcarbanucleosides as Potential Anti-HCV Agents | Full Text | References | PDF (185.5 KB)
  • 112 Views
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Article
Syntheses of Pyrimidine Acyclic Nucleoside Phosphonates as Potent Inhibitors of Thymidine Phosphorylase (PD-ECGF) from SD-Lymphoma
Karel Pomeisl, Ivan Votruba, Antonín Holý & Radek Pohl
Pages: 1025-1028
Published online: 10 Dec 2007
AbstractforSyntheses of Pyrimidine Acyclic Nucleoside Phosphonates as Potent Inhibitors of Thymidine Phosphorylase (PD-ECGF) from SD-Lymphoma | Full Text | References | PDF (72.3 KB)
  • 95 Views
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Article
Diastereoselective Synthesis of 2′,3′-Dideoxy- β-C- Glucopyranosides as Intermediates for the Synthesis of 2′,3′-Dideoxy-β-D-Glucopyranosyl-C-Nucleosides
Michael Löpfe & Jay S. Siegel
Pages: 1029-1035
Published online: 10 Dec 2007
AbstractforDiastereoselective Synthesis of 2′,3′-Dideoxy- β-C- Glucopyranosides as Intermediates for the Synthesis of 2′,3′-Dideoxy-β-D-Glucopyranosyl-C-Nucleosides | Full Text | References | PDF (243.6 KB)
  • 81 Views
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Article
Studies on Thermal Stability of Human Cytidine Deaminase
S. Vincenzetti, S. Pucciarelli, P. Mariani, G. De Sanctis, V. Polzonetti, P. Natalini & A. Vita
Pages: 1037-1042
Published online: 10 Dec 2007
AbstractforStudies on Thermal Stability of Human Cytidine Deaminase | Full Text | References | PDF (201.7 KB)
  • 51 Views
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Article
The Effects of Nucleoside Analogues on Promoter Methylation of Selected Tumor Suppressor Genes in MCF-7 and MDA-MB-231 Breast Cancer Cell Lines
B. Krawczyk, K. Rudnicka & K. Fabianowska-Majewska
Pages: 1043-1046
Published online: 10 Dec 2007
AbstractforThe Effects of Nucleoside Analogues on Promoter Methylation of Selected Tumor Suppressor Genes in MCF-7 and MDA-MB-231 Breast Cancer Cell Lines | Full Text | References | PDF (51.1 KB)
  • 200 Views
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Article
ODN-Based Drugs for Targeting of Extracellular Proteins
E. M. Bucci, M. Valente, D. Musumeci, R. Sapio, V. Anrò, G. N. Roviello & M. Moccia
Pages: 1047-1050
Published online: 10 Dec 2007
AbstractforODN-Based Drugs for Targeting of Extracellular Proteins | Full Text | References | PDF (180 KB)
  • 43 Views
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Article
Novel S-Ribosylhomocysteine Analogues as Potential Inhibitors of LuxS Enzyme
Stanislaw F. Wnuk, Jennifer Lalama, Jenay Robert & Craig A. Garmendia
Pages: 1051-1055
Published online: 10 Dec 2007
AbstractforNovel S-Ribosylhomocysteine Analogues as Potential Inhibitors of LuxS Enzyme | Full Text | References | PDF (158.3 KB)
  • 76 Views
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Article
A New Family of Inhibitors of Mycobacterium Tuberculosis Thymidine Monophosphate Kinase
C. Gasse, V. Huteau, D. Douguet, H. Munier-Lehmann & S. Pochet
Pages: 1057-1061
Published online: 10 Dec 2007
First Page PreviewforA New Family of Inhibitors of Mycobacterium Tuberculosis Thymidine Monophosphate Kinase | Full Text | References | PDF (264.1 KB)
  • 48 Views
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Article
Investigation of Novel Lipid-Functionalized PNA Monomers as Potential HIV-1 Non-Nucleoside Reverse Transcriptase and/or Integrase Inhibitors
Michael G. Thomas, Giovanni Maga, Jean-François Mouscadet & Nicola M. Howarth
Pages: 1063-1066
Published online: 10 Dec 2007
AbstractforInvestigation of Novel Lipid-Functionalized PNA Monomers as Potential HIV-1 Non-Nucleoside Reverse Transcriptase and/or Integrase Inhibitors | Full Text | References | PDF (76.8 KB)
  • 55 Views
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Article
Telomere Shortening in Human HL60 Cells by Treatment with 3′-Azido-2′,3′-Dideoxynucleosides and Telomerase Inhibition by Their 5′-Triphosphates
Xiaohong Liu, Motoko Inomata, Tsukasa Ogawara, Mineo Saneyoshi & Toyofumi Yamaguchi
Pages: 1067-1071
Published online: 10 Dec 2007
AbstractforTelomere Shortening in Human HL60 Cells by Treatment with 3′-Azido-2′,3′-Dideoxynucleosides and Telomerase Inhibition by Their 5′-Triphosphates | Full Text | References | PDF (976.4 KB)
  • 42 Views
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Article
Troxacitabine Prodrugs for Pancreatic Cancer
A. D. Adema, M. Radi, J. Daft, J. Narayanasamy, E. K. Hoebe, L. E. Alexander, C. K. Chu & G. J. Peters
Pages: 1073-1077
Published online: 10 Dec 2007
AbstractforTroxacitabine Prodrugs for Pancreatic Cancer | Full Text | References | PDF (134 KB)
  • 142 Views
  • 10 CrossRef citations
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Article
Synthesis of Novel 2′-Deoxy Type Trans-3′,4′-Bridged Nucleic Acid
Tomohisa Osaki, Satoshi Obika, Yasuki Harada, Yasunori Mitsuoka, Kensaku Sugaya, Mitsuaki Sekiguchi, Somjing Roongjang & Takeshi Imanishi
Pages: 1079-1082
Published online: 10 Dec 2007
AbstractforSynthesis of Novel 2′-Deoxy Type Trans-3′,4′-Bridged Nucleic Acid | Full Text | References | PDF (86.6 KB)
  • 47 Views
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Article
Furano- and Pyrrolo [2,3-D] Pyrimidine Nucleosides and Their 5′-O-Triphospates: Synthesis and Enzymatic Activity
L. A. Alexandrova, M. A. Ivanov, L. S. Victorova & M. K. Kukhanova
Pages: 1083-1086
Published online: 10 Dec 2007
AbstractforFurano- and Pyrrolo [2,3-D] Pyrimidine Nucleosides and Their 5′-O-Triphospates: Synthesis and Enzymatic Activity | Full Text | References | PDF (305.9 KB)
  • 108 Views
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Article
Approach to the Synthesis of Natural and Modified Oligonucleotides by the Phosphotriester Method Using O-Nucleophilic Intramolecular Catalysis
Vladimir A. Efimov, Natalia S. Molchanova & Oksana G. Chakhmakhcheva
Pages: 1087-1093
Published online: 10 Dec 2007
AbstractforApproach to the Synthesis of Natural and Modified Oligonucleotides by the Phosphotriester Method Using O-Nucleophilic Intramolecular Catalysis | Full Text | References | PDF (661.6 KB)
  • 257 Views
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Article
Glycosylation Reaction via a Mild and Efficient One-Pot Reaction Using Doped Natural Phosphate with Iodine as Catalyst
H. B. Lazrek, D. Ouzebla, L. Baddi & J. J. Vasseur
Pages: 1095-1098
Published online: 10 Dec 2007
AbstractforGlycosylation Reaction via a Mild and Efficient One-Pot Reaction Using Doped Natural Phosphate with Iodine as Catalyst | Full Text | References | PDF (64 KB)
  • 99 Views
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Article
The Synthesis and Properties of Tricyclic Analogues of S6–MethylthioguanineandO6-Methylguanine
Ana R. Hornillo-Araujo, Adam J. M. Burrell, Miren K. Aiertza, Takayuki Shibata, David M. Hammond, Dolorès Edmont, Harry Adams, Geoffrey P. Margison & David M. Williams
Pages: 1099-1102
Published online: 10 Dec 2007
AbstractforThe Synthesis and Properties of Tricyclic Analogues of S6–MethylthioguanineandO6-Methylguanine | Full Text | References | PDF (176.6 KB)
  • 70 Views
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Article
A Glutaric Acid Ester as Carrier System for Sustained Delivery of Lamuvidine (3TC) Dimers
H. B. Lazrek, J. J. Vasseur, Jack Secrist III & Joachim W. Engels
Pages: 1103-1106
Published online: 10 Dec 2007
AbstractforA Glutaric Acid Ester as Carrier System for Sustained Delivery of Lamuvidine (3TC) Dimers | Full Text | References | PDF (84.9 KB)
  • 57 Views
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Article
Synthesis and Anti-HSV Activity of new N1-Acyclic C4 and C6-Disubstituted Pyrazolo[3,4-D]Pyrimidine Nucleosides
Omar Moukha-chafiq, Mohamed Labd Taha & Abdelmalek Mouna
Pages: 1107-1110
Published online: 10 Dec 2007
AbstractforSynthesis and Anti-HSV Activity of new N1-Acyclic C4 and C6-Disubstituted Pyrazolo[3,4-D]Pyrimidine Nucleosides | Full Text | References | PDF (177.7 KB)
  • 50 Views
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Article
Stereospecific Synthesis of (−)-Neplanocin F
Sergio Rodriguez Ropero, Dolorès Edmont, Christophe Mathé & Christian Périgaud
Pages: 1111-1114
Published online: 10 Dec 2007
AbstractforStereospecific Synthesis of (−)-Neplanocin F | Full Text | References | PDF (168.1 KB)
  • 72 Views
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Article
Effect of Cationic Comb-Type Copolymer on Quadruplex Folding of Human Telomeric DNA
Naoki Makita, Sung Won Choi, Arihiro Kano, Asako Yamayoshi, Toshihiro Akaike & Atsushi Maruyama
Pages: 1115-1119
Published online: 10 Dec 2007
AbstractforEffect of Cationic Comb-Type Copolymer on Quadruplex Folding of Human Telomeric DNA | Full Text | References | PDF (135.1 KB)
  • 56 Views
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Article
Molecular Modelling Studies on the Binding of Some Protides to the Putative Human Phosphoramidase Hint1
C. Congiatu, A. Brancale & C. McGuigan
Pages: 1121-1124
Published online: 10 Dec 2007
AbstractforMolecular Modelling Studies on the Binding of Some Protides to the Putative Human Phosphoramidase Hint1 | Full Text | References | PDF (221.3 KB)
  • 224 Views
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Article
Revisited 3′-Deoxy-3′-C-Methyl-β-D-Ribonucleoside Series
Mohamed Aljarah, Sarah Couturier, Gilles Gosselin, Christophe Mathé & Christian Périgaud
Pages: 1125-1128
Published online: 10 Dec 2007
AbstractforRevisited 3′-Deoxy-3′-C-Methyl-β-D-Ribonucleoside Series | Full Text | References | PDF (165.3 KB)
  • 258 Views
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Article
Effect of Rubidium and Cesium Ions on the Dimeric Quaduplex formed by the Oxytricha Nova Telomeric Repeat Oligonucleotide D(GGGGTTTTGGGG)
Flaminia Cesare Marincola, Ada Virno, Antonio Randazzo & Adolfo Lai
Pages: 1129-1132
Published online: 10 Dec 2007
AbstractforEffect of Rubidium and Cesium Ions on the Dimeric Quaduplex formed by the Oxytricha Nova Telomeric Repeat Oligonucleotide D(GGGGTTTTGGGG) | Full Text | References | PDF (147 KB)
  • 106 Views
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Article
Structural insight into the h TERT intron 6 sequence d(GGGGTGAAAGGGG) from 1H-NMR study
Ada Virno, Luciano Mayol, Andres Ramos, Franca Fraternali, Bruno Pagano & Antonio Randazzo
Pages: 1133-1137
Published online: 10 Dec 2007
AbstractforStructural insight into the h TERT intron 6 sequence d(GGGGTGAAAGGGG) from 1H-NMR study | Full Text | References | PDF (198.8 KB)
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Molecular Modelling Studies of Four Stranded Quadruplexes Containing A 3′-3′ or 5′-5′ Inversion of Polarity Site
Ada Virno, Francesco Zaccaria, Antonella Virgilio, Veronica Esposito, Aldo Galeone, Luciano Mayol & Antonio Randazzo
Pages: 1139-1143
Published online: 10 Dec 2007
AbstractforMolecular Modelling Studies of Four Stranded Quadruplexes Containing A 3′-3′ or 5′-5′ Inversion of Polarity Site | Full Text | References | PDF (2.2 MB)
  • 122 Views
  • 7 CrossRef citations
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Article
A Mini-Library of TBA Analogues Containing 3′-3′ and 5′-5′ Inversion of Polarity Sites
V. Esposito, A. Galeone, L. Mayol, A. Randazzo, A. Virgilio & A. Virno
Pages: 1145-1149
Published online: 10 Dec 2007
AbstractforA Mini-Library of TBA Analogues Containing 3′-3′ and 5′-5′ Inversion of Polarity Sites | Full Text | References | PDF (335.2 KB)
  • 108 Views
  • 15 CrossRef citations
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Article
Effect of the Introduction of an A-Residue into A Quadruplex Forming Oligonucleotide Containing A 5′-5′ Polarity of Inversion Site
A. Galeone, L. Mayol, A. Randazzo, A. Virgilio & A. Virno
Pages: 1151-1154
Published online: 10 Dec 2007
AbstractforEffect of the Introduction of an A-Residue into A Quadruplex Forming Oligonucleotide Containing A 5′-5′ Polarity of Inversion Site | Full Text | References | PDF (133.5 KB)
  • 44 Views
  • 1 CrossRef citations
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Article
A Topological Classification of G-Quadruplex Structures
V. Esposito, A. Galeone, L. Mayol, G. Oliviero, A. Virgilio & L. Randazzo
Pages: 1155-1159
Published online: 10 Dec 2007
AbstractforA Topological Classification of G-Quadruplex Structures | Full Text | References | PDF (259.6 KB)
  • 260 Views
  • 27 CrossRef citations
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Synthesis and Primary Evaluation of Novel HIV-1 Inhibitors
Yazan El Safadi, Roland Marquet, Anne-Marie Aubertin & Valérie Vivet-Boudou
Pages: 1161-1165
Published online: 10 Dec 2007
AbstractforSynthesis and Primary Evaluation of Novel HIV-1 Inhibitors | Full Text | References | PDF (81.4 KB)
  • 124 Views
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The Support-on-Support Concept for In-Situ Oligonucleotide Synthesis on Nanoparticles
H. Seliger, M. Hinz, R. Ditz, M. Koch, P. Lapido & S. Margel
Pages: 1167-1172
Published online: 10 Dec 2007
AbstractforThe Support-on-Support Concept for In-Situ Oligonucleotide Synthesis on Nanoparticles | Full Text | References | PDF (266.9 KB)
  • 78 Views
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Thermodynamic Studies on PNA and PNA/DNA Dendrimer Formation
Maria Moccia, Domenica Musumeci, Margherita Valente, Giovanni N. Roviello, Roberto Sapio, Carlo Pedone & Enrico M. Bucci
Pages: 1173-1176
Published online: 10 Dec 2007
AbstractforThermodynamic Studies on PNA and PNA/DNA Dendrimer Formation | Full Text | References | PDF (214.4 KB)
  • 82 Views
  • 2 CrossRef citations
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Photochemically Induced RNA and DNA Abasic Sites
Pascal A. Küpfer & Christian J. Leumann
Pages: 1177-1180
Published online: 10 Dec 2007
AbstractforPhotochemically Induced RNA and DNA Abasic Sites | Full Text | References | PDF (521.8 KB)
  • 178 Views
  • 2 CrossRef citations
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Cyclopentane-Nucleobase Coupling in the Synthesis of Carbocyclic L-Nucleosides: is A SN2-Reaction an Alternative to the Mitsunobu-Reaction?
S. Jessel, E. Hense & C. Meier
Pages: 1181-1184
Published online: 10 Dec 2007
AbstractforCyclopentane-Nucleobase Coupling in the Synthesis of Carbocyclic L-Nucleosides: is A SN2-Reaction an Alternative to the Mitsunobu-Reaction? | Full Text | References | PDF (69.2 KB)
  • 222 Views
  • 6 CrossRef citations
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Synthesis and Properties of Oligonucleotides Containing A 7-Membered (Oxepane) Sugar Ring
David Sabatino & Masad J. Damha
Pages: 1185-1188
Published online: 10 Dec 2007
AbstractforSynthesis and Properties of Oligonucleotides Containing A 7-Membered (Oxepane) Sugar Ring | Full Text | References | PDF (151.9 KB)
  • 96 Views
  • 5 CrossRef citations
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DNA Polymerase Recognition of 2′-Deoxy-2′-Fluoroarabinonucleoside 5′-Triphosphates (2′F-Arantps)
Chang G. Peng & Masad J. Damha
Pages: 1189-1193
Published online: 10 Dec 2007
AbstractforDNA Polymerase Recognition of 2′-Deoxy-2′-Fluoroarabinonucleoside 5′-Triphosphates (2′F-Arantps) | Full Text | References | PDF (978.3 KB)
  • 142 Views
  • 3 CrossRef citations
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Introduction of Chirality into PNA By Replacement of the Achiral Methylene Carbonyl Linkage to the Nucleobase
Filip Wojciechowski & Robert H. E. Hudson
Pages: 1195-1198
Published online: 10 Dec 2007
AbstractforIntroduction of Chirality into PNA By Replacement of the Achiral Methylene Carbonyl Linkage to the Nucleobase | Full Text | References | PDF (64.5 KB)
  • 208 Views
  • 2 CrossRef citations
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Synthesis of A Fluorescent PNA Monomer Containing 5-((9H-Fluoren-2-YL)Ethynyl)Uracil
Filip Wojciechowski & Robert H. E. Hudson
Pages: 1199-1202
Published online: 10 Dec 2007
AbstractforSynthesis of A Fluorescent PNA Monomer Containing 5-((9H-Fluoren-2-YL)Ethynyl)Uracil | Full Text | References | PDF (80 KB)
  • 182 Views
  • 4 CrossRef citations
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Synthesis of Modified Nucleosides for Incorporation of Formyletheno and Carboxyetheno Adducts of Adenine Nucleosides into Oligonucleotides
Niangoran Koissi & Harri Lönnberg
Pages: 1203-1206
Published online: 10 Dec 2007
AbstractforSynthesis of Modified Nucleosides for Incorporation of Formyletheno and Carboxyetheno Adducts of Adenine Nucleosides into Oligonucleotides | Full Text | References | PDF (80.7 KB)
  • 106 Views
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In Vitro Incorporation of LNA Nucleotides
Rakesh N. Veedu, Birte Vester & Jesper Wengel
Pages: 1207-1210
Published online: 10 Dec 2007
AbstractforIn Vitro Incorporation of LNA Nucleotides | Full Text | References | PDF (344.9 KB)
  • 230 Views
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