Redox Report, Volume 27, Issue 1 (2022)

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Redox Report, Volume 27, Issue 1 (2022)

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Research Article

Article
Alfalfa saponins inhibit oxidative stress-induced cell apoptosis through the MAPK signaling pathway
Yalei Cui, Fen Li, Xiaoyan Zhu, Junying Xu, Abaidullah Muhammad, Yanyan Chen, Defeng Li, Boshuai Liu, Chengzhang Wang, Zhichang Wang, Sen Ma, Xule Liu & Yinghua Shi
Pages: 1-8
Published online: 21 Dec 2021
AbstractforAlfalfa saponins inhibit oxidative stress-induced cell apoptosis through the MAPK signaling pathway | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Chemopreventive and hepatoprotective effects of genistein via inhibition of oxidative stress and the versican/PDGF/PKC signaling pathway in experimentally induced hepatocellular carcinoma in rats by thioacetamide
Yousra M. El-Far, Ahmed E. Khodir, Ziad A. Emarah, Mohamed A. Ebrahim & Mohammed M. H. Al-Gayyar
Pages: 9-20
Published online: 26 Jan 2022
AbstractforChemopreventive and hepatoprotective effects of genistein via inhibition of oxidative stress and the versican/PDGF/PKC signaling pathway in experimentally induced hepatocellular carcinoma in rats by thioacetamide | Full Text | References | PDF (5.3 MB) | EPUB
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Open Access
Article
The emerging role of irisin in experimentally induced arthritis: a recent update involving HMGB1/MCP1/Chitotriosidase I–mediated necroptosis
Rowida Raafat Ibrahim, Noha M. Shafik, Rasha Osama El-Esawy, Mervat H. El-Sakaa, Heba M. Arakeeb, Radwa Mahmoud El-Sharaby, Dina Adam Ali, Omnia Safwat El-deeb & Sara Ragab Abd El-Khalik
Pages: 21-31
Published online: 29 Jan 2022
AbstractforThe emerging role of irisin in experimentally induced arthritis: a recent update involving HMGB1/MCP1/Chitotriosidase I–mediated necroptosis | Full Text | References | PDF (2.4 MB) | EPUB
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Open Access
Article
Lycium Barbarum polysaccharide protects HaCaT cells from PM2.5-induced apoptosis via inhibiting oxidative stress, ER stress and autophagy
Sen Zhu, Xuan Li, Bingrong Dang, Fen Wu, Chunming Wang & Changjun Lin
Pages: 32-44
Published online: 07 Feb 2022
AbstractforLycium Barbarum polysaccharide protects HaCaT cells from PM2.5-induced apoptosis via inhibiting oxidative stress, ER stress and autophagy | Full Text | References | PDF (4.8 MB) | EPUB
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Review Article

Review Article
Role of mitochondrial reactive oxygen species in homeostasis regulation
Baoyi Zhang, Cunyao Pan, Chong Feng, Changqing Yan, Yijing Yu, Zhaoli Chen, Changjiang Guo & Xinxing Wang
Pages: 45-52
Published online: 25 Feb 2022
AbstractforRole of mitochondrial reactive oxygen species in homeostasis regulation | Full Text | References | PDF (1.2 MB) | EPUB
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Review Article
Psychostimulants influence oxidative stress and redox signatures: the role of DNA methylation
Vaishnavi Sundar, Tamizhselvi Ramasamy, Mayur Doke & Thangavel Samikkannu
Pages: 53-59
Published online: 28 Feb 2022
AbstractforPsychostimulants influence oxidative stress and redox signatures: the role of DNA methylation | Full Text | References | PDF (1.2 MB) | EPUB
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Research Article

Article
Modulating gut dysbiosis and mitochondrial dysfunction in oxazolone-induced ulcerative colitis: the restorative effects of β-glucan and/or celastrol
Omnia Safwat El-Deeb, Rasha Osama El-Esawy, Hanan Alsaeid Al-Shenawy & Heba Bassiony Ghanem
Pages: 60-69
Published online: 04 Mar 2022
AbstractforModulating gut dysbiosis and mitochondrial dysfunction in oxazolone-induced ulcerative colitis: the restorative effects of β-glucan and/or celastrol | Full Text | References | PDF (2.6 MB) | EPUB
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Open Access
Article
The evolving role of long noncoding RNA HIF1A-AS2 in diabetic retinopathy: a cross-link axis between hypoxia, oxidative stress and angiogenesis via MAPK/VEGF-dependent pathway
Marwa Mohamed Atef, Noha M. Shafik, Yasser Mostafa Hafez, Mona Mohamed Watany, Amal Selim, Heba M. Shafik & Omnia Safwat El-Deeb
Pages: 70-78
Published online: 14 Mar 2022
AbstractforThe evolving role of long noncoding RNA HIF1A-AS2 in diabetic retinopathy: a cross-link axis between hypoxia, oxidative stress and angiogenesis via MAPK/VEGF-dependent pathway | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Open Access
Article
Serum uric acid level predicts the progression of amyotrophic lateral sclerosis following treatment with edaravone
Hee Jo Han, Ha Young Shin, Young-Chul Choi, Seung Min Kim & Seung Woo Kim
Pages: 79-84
Published online: 16 Mar 2022
AbstractforSerum uric acid level predicts the progression of amyotrophic lateral sclerosis following treatment with edaravone | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Open Access
Article
SOD2 rs4880 and GPX1 rs1050450 polymorphisms do not confer risk of COVID-19, but influence inflammation or coagulation parameters in Serbian cohort
Djurdja Jerotic, Jovan Ranin, Zoran Bukumiric, Tatjana Djukic, Vesna Coric, Ana Savic-Radojevic, Nevena Todorovic, Milika Asanin, Marko Ercegovac, Ivana Milosevic, Marija Pljesa-Ercegovac, Goran Stevanovic, Marija Matic & Tatjana Simic
Pages: 85-91
Published online: 31 Mar 2022
AbstractforSOD2 rs4880 and GPX1 rs1050450 polymorphisms do not confer risk of COVID-19, but influence inflammation or coagulation parameters in Serbian cohort | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
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Open Access
Article
D-limonene (5 (one-methyl-four-[1-methylethenyl]) cyclohexane) diminishes CCl4-induced cardiac toxicity by alleviating oxidative stress, inflammatory and cardiac markers
Rana M. AlSaffar, Summya Rashid, Sheikh Bilal Ahmad, Muneeb U. Rehman, Ishraq Hussain, Sheikh Parvaiz Ahmad & Majid Ahmad Ganaie
Pages: 92-99
Published online: 17 Apr 2022
AbstractforD-limonene (5 (one-methyl-four-[1-methylethenyl]) cyclohexane) diminishes CCl4-induced cardiac toxicity by alleviating oxidative stress, inflammatory and cardiac markers | Full Text | References | PDF (1.9 MB) | EPUB
  • 2642 Views
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Open Access
Article
Hydrogen sulfide protects retina from blue light-induced photodamage and degeneration via inhibiting ROS-mediated ER stress-CHOP apoptosis signal
Sen Zhu, Xuan Li, Bingrong Dang, Fen Wu, Kexin Gou, Chunming Wang & Changjun Lin
Pages: 100-110
Published online: 28 Apr 2022
AbstractforHydrogen sulfide protects retina from blue light-induced photodamage and degeneration via inhibiting ROS-mediated ER stress-CHOP apoptosis signal | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 1918 Views
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Open Access
Article
Suppression of glutathione system and upregulation of caspase 3-dependent apoptosis mediate rohypnol-induced gastric injury
R. E. Akhigbe, D. T. Oluwole, T. E. Adegoke, M. A. Hamed, D. C. Anyogu & A. F. Ajayi
Pages: 111-118
Published online: 10 May 2022
AbstractforSuppression of glutathione system and upregulation of caspase 3-dependent apoptosis mediate rohypnol-induced gastric injury | Full Text | References | PDF (2 MB) | EPUB
  • 1436 Views
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Open Access
Article
Norcantharidin down-regulates iron contents in the liver and spleen of lipopolysaccharide-treated mice
Jie Zheng, Jiao-Jiao Wang, Hui-Min Ma, Meng-Qi Shen, Zhong-Ming Qian & Yu-Xin Bao
Pages: 119-127
Published online: 23 Jun 2022
AbstractforNorcantharidin down-regulates iron contents in the liver and spleen of lipopolysaccharide-treated mice | Full Text | References | PDF (2.3 MB) | EPUB
  • 1752 Views
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Open Access
Article
Therapeutic effects of sulforaphane in ulcerative colitis: effect on antioxidant activity, mitochondrial biogenesis and DNA polymerization
Abdullah Alattar, Reem Alshaman & Mohammed M. H. Al-Gayyar
Pages: 128-138
Published online: 26 Jun 2022
AbstractforTherapeutic effects of sulforaphane in ulcerative colitis: effect on antioxidant activity, mitochondrial biogenesis and DNA polymerization | Full Text | References | PDF (2.7 MB) | EPUB
  • 2929 Views
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Open Access
Article
Sevoflurane reduces lipopolysaccharide-induced apoptosis and pulmonary fibrosis in the RAW264.7 cells and mice models to ameliorate acute lung injury by eliminating oxidative damages
Fushuang Zheng, Xiuying Wu, Jin Zhang, Zhiling Fu & Yan Zhang
Pages: 139-149
Published online: 08 Jul 2022
AbstractforSevoflurane reduces lipopolysaccharide-induced apoptosis and pulmonary fibrosis in the RAW264.7 cells and mice models to ameliorate acute lung injury by eliminating oxidative damages | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 2797 Views
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Open Access
Article
Redox-sensitive small GTPase H-Ras in murine astrocytes, an in vitro study
Candida Zuchegna, Valeria de Rosa, Francesca Boscia, Antonio Porcellini & Samantha Messina
Pages: 150-157
Published online: 13 Jul 2022
AbstractforRedox-sensitive small GTPase H-Ras in murine astrocytes, an in vitro study | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 961 Views
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Open Access
Article
Beneficial role of naringin against methotrexate-induced injury to rat testes: biochemical and ultrastructural analyses
Hany Elsawy, Abdullah M. Alzahrani, Manal Alfwuaires, Ashraf M. Abdel-Moneim & Mahmoud Khalil
Pages: 158-166
Published online: 21 Jul 2022
AbstractforBeneficial role of naringin against methotrexate-induced injury to rat testes: biochemical and ultrastructural analyses | Full Text | References | PDF (3.5 MB) | EPUB
  • 1246 Views
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Open Access
Article
miR-34a induces neutrophil apoptosis by regulating Cdc42-WASP-Arp2/3 pathway-mediated F-actin remodeling and ROS production
Meiwan Cao, Baoling Peng, Huan Chen, Min Yang, Peiyu Chen, Liping Ye, Hongli Wang, Lu Ren, Jing Xie, Jingnan Zhu, Xiangye Xu, Wanfu Xu, Lanlan Geng & Sitang Gong
Pages: 167-175
Published online: 06 Aug 2022
AbstractformiR-34a induces neutrophil apoptosis by regulating Cdc42-WASP-Arp2/3 pathway-mediated F-actin remodeling and ROS production | Full Text | References | PDF (2.6 MB) | EPUB
  • 1646 Views
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Correction

Correction
Correction
Page: 176
Published online: 16 Aug 2022
CitationforCorrection | Full Text | PDF (98.6 KB) | EPUB
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Free Access

Research Article

Article
Fisetin ameliorates oxidative glutamate testicular toxicity in rats via central and peripheral mechanisms involving SIRT1 activation
Fatma H. Rizk, Nema A. Soliman, Suzan E. Abo-Elnasr, Heba A. Mahmoud, Muhammad T. Abdel Ghafar, Rasha A. Elkholy, Ola A. ELshora, Reham A. Mariah, Shaimaa Samir Amin Mashal & Amira A. El Saadany
Pages: 177-185
Published online: 01 Sep 2022
AbstractforFisetin ameliorates oxidative glutamate testicular toxicity in rats via central and peripheral mechanisms involving SIRT1 activation | Full Text | References | PDF (2.5 MB) | EPUB
  • 1669 Views
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Open Access
Article
Effect of 6-week curcumin supplementation on aerobic capacity, antioxidant status and sirtuin 3 level in middle-aged amateur long-distance runners
Sebastian Bańkowski, Miroslav Petr, Michał Rozpara & Ewa Sadowska-Krępa
Pages: 186-192
Published online: 20 Sep 2022
AbstractforEffect of 6-week curcumin supplementation on aerobic capacity, antioxidant status and sirtuin 3 level in middle-aged amateur long-distance runners | Full Text | References | PDF (770 KB) | EPUB
  • 1908 Views
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Open Access

Review Article

Review Article
Damage-associated molecular patterns in vitiligo: igniter fuse from oxidative stress to melanocyte loss
Jingying Wang, Yinghao Pan, Guangmin Wei, Hanxiao Mao, Rulan Liu & Yuanmin He
Pages: 193-199
Published online: 26 Sep 2022
AbstractforDamage-associated molecular patterns in vitiligo: igniter fuse from oxidative stress to melanocyte loss | Full Text | References | PDF (856.3 KB) | EPUB
  • 2397 Views
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Research Article

Article
The protective effect of proanthocyanidins on the psoriasis-like cell models via PI3K/AKT and HO-1
Yangmeng Zhao, Yuxin Xie, Xiaolong Li, Jing Song, Menglu Guo, Dehai Xian & Jianqiao Zhong
Pages: 200-211
Published online: 30 Sep 2022
AbstractforThe protective effect of proanthocyanidins on the psoriasis-like cell models via PI3K/AKT and HO-1 | Full Text | References | PDF (2.5 MB) | EPUB
  • 1580 Views
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Open Access
Article
Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury
O. A. Afolabi, M. A. Hamed, D. C. Anyogu, D. H. Adeyemi, A. F. Odetayo & R. E. Akhigbe
Pages: 212-220
Published online: 06 Oct 2022
AbstractforAtorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury | Full Text | References | PDF (2 MB) | EPUB
  • 1099 Views
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Open Access
Article
Chili-supplemented food decreases glutathione-S-transferase activity in Drosophila melanogaster females without a change in other parameters of antioxidant system
Uliana V. Semaniuk, Dmytro V. Gospodaryov, Olha M. Strilbytska, Alicja Z. Kucharska, Anna Sokół-Łętowska, Nadia I. Burdyliuk, Kenneth B. Storey, Maria M. Bayliak & Oleh Lushchak
Pages: 221-229
Published online: 06 Oct 2022
AbstractforChili-supplemented food decreases glutathione-S-transferase activity in Drosophila melanogaster females without a change in other parameters of antioxidant system | Full Text | References | PDF (1.3 MB) | EPUB
  • 1056 Views
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Open Access
Article
Swinhoeic acid from Potentilla fragarioides ameliorates high glucose-induced oxidative stress and accumulation of ECM in mesangial cells via Keap1-dependent activation of Nrf2
Huankai Yao, Min Kong, Dan Du, Fengwei Ai, Jindong Li & Yan Li
Pages: 230-238
Published online: 19 Oct 2022
AbstractforSwinhoeic acid from Potentilla fragarioides ameliorates high glucose-induced oxidative stress and accumulation of ECM in mesangial cells via Keap1-dependent activation of Nrf2 | Full Text | References | PDF (2.3 MB) | EPUB
  • 984 Views
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Article
β-catenin ISGylation promotes lipid deposition and apoptosis in ethanol-stimulated liver injury models
Qi Ding, Guodong Zhang, Yang Wang, Lei Xu, Meifei Wu, Yiwen Zhou, Tao Xu, Xiaoming Meng, Cheng Huang & Lei Zhang
Pages: 239-248
Published online: 19 Oct 2022
Abstractforβ-catenin ISGylation promotes lipid deposition and apoptosis in ethanol-stimulated liver injury models | Full Text | References | PDF (2.8 MB) | EPUB
  • 1364 Views
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Open Access
Article
Zinc oxide nanoparticles and spironolactone-enhanced Nrf2/HO-1 pathway and inhibited Wnt/β-catenin pathway in adenine-induced nephrotoxicity in rats
Amira Awadalla, Eman T. Hamam, Fardous F. El-Senduny, Nisreen Mansour Omar, Mohamed R. Mahdi, Nashwa Barakat, Omar A. Ammar, Abdelaziz M. Hussein, Ahmed A. Shokeir & Salma M. Khirallah
Pages: 249-258
Published online: 07 Nov 2022
AbstractforZinc oxide nanoparticles and spironolactone-enhanced Nrf2/HO-1 pathway and inhibited Wnt/β-catenin pathway in adenine-induced nephrotoxicity in rats | Full Text | References | PDF (3.2 MB) | EPUB
  • 1405 Views
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Article
Evaluation of targeted oxidative stress induced by oxygen-ozone in vitro after ischemic induction
Jessica Rodrigues Orlandin, Sarah Ingrid Pinto Santos, Luciana Cristina Machado, Paulo Fantinato Neto, Fabiana Fernandes Bressan, Naira Caroline Godoy Pieri, Kaiana Recchia, Meline de Paula Coutinho, Priscilla Avelino Ferreira Pinto, Annalisa Santucci, Valter Travagli & Carlos Eduardo Ambrosio
Pages: 259-269
Published online: 10 Nov 2022
AbstractforEvaluation of targeted oxidative stress induced by oxygen-ozone in vitro after ischemic induction | Full Text | References | PDF (2.3 MB) | EPUB
  • 1301 Views
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Article
Caffeine reduces oxidative stress to protect against hyperoxia-induced lung injury via the adenosine A2A receptor/cAMP/PKA/Src/ERK1/2/p38MAPK pathway
Xijuan Wang, Shuai Lv, Jianwei Sun, Meihui Zhang, Lei Zhang, Yan Sun, Ziyan Zhao, Dandan Wang, Xinjing Zhao & Jiajie Zhang
Pages: 270-278
Published online: 10 Nov 2022
AbstractforCaffeine reduces oxidative stress to protect against hyperoxia-induced lung injury via the adenosine A2A receptor/cAMP/PKA/Src/ERK1/2/p38MAPK pathway | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
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