Cell Cycle, Volume 11, Issue 2 (2012)

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Cell Cycle, Volume 11, Issue 2 (2012)

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Special Feature

Review Article
A new chronological survival assay in mammalian cell culture
Matt Kaeberlein & Brian K Kennedy
Pages: 201-202
Published online: 15 Jan 2012
CitationforA new chronological survival assay in mammalian cell culture | Full Text | References | PDF (167 KB)
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Editorials: Cell Cycle Features

Editorial
Detection of circulating tumor cells in the cerebrospinal fluid: A new frontier
Timothy F. Burns & Antonio C. Wolff
Pages: 203-204
Published online: 15 Jan 2012
AbstractforDetection of circulating tumor cells in the cerebrospinal fluid: A new frontier | PDF (168.3 KB)
  • 213 Views
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Editorial
Sensing senescence in preterm birth
Jeeyeon Cha, Yasushi Hirota & Sudhansu K. Dey
Pages: 205-206
Published online: 15 Jan 2012
AbstractforSensing senescence in preterm birth | PDF (336.6 KB)
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Editorial
The signaling requirements for mouse embryonic stem cells
Dorota Kurek & Derk ten Berge
Pages: 207-208
Published online: 15 Jan 2012
AbstractforThe signaling requirements for mouse embryonic stem cells | PDF (172.5 KB)
  • 432 Views
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Editorial
Genetic variability in the PRKCI gene and prostate cancer risk
Daniele Campa, Federico Canzian & Rudolf Kaaks
Page: 209
Published online: 15 Jan 2012
AbstractforGenetic variability in the PRKCI gene and prostate cancer risk | PDF (126.9 KB)
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Editorial
Providing the TORC for cell cycle progression in neoplastic mast cells
Daniel Smrž, Todd M. Wilson, Dean D. Metcalfe & Alasdair M. Gilfillan
Pages: 210-211
Published online: 15 Jan 2012
AbstractforProviding the TORC for cell cycle progression in neoplastic mast cells | Full Text | References | PDF (951 KB)
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Cell Cycle News & Views

Bipolar disorder: Kinesin-12 to the rescue
Julien Dumont
Page: 212
Published online: 15 Jan 2012
AbstractforBipolar disorder: Kinesin-12 to the rescue | PDF (922.7 KB)
  • 204 Views
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Open Access
Brain and muscle ARNT-like protein BMAL1 regulates ROS homeostasis and senescence: A possible link to hypoxia-inducible factor-mediated pathway
Olga V. Razorenova
Page: 213
Published online: 15 Jan 2012
AbstractforBrain and muscle ARNT-like protein BMAL1 regulates ROS homeostasis and senescence: A possible link to hypoxia-inducible factor-mediated pathway | PDF (909.2 KB)
  • 526 Views
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The evolution of the p53 family of genes
Arnold J. Levine
Page: 214
Published online: 15 Jan 2012
AbstractforThe evolution of the p53 family of genes | PDF (909.2 KB)
  • 408 Views
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MiR-34 and SNAIL: Another double-negative feedback loop controlling cellular plasticity/EMT governed by p53
Thomas Brabletz
Page: 215
Published online: 15 Jan 2012
AbstractforMiR-34 and SNAIL: Another double-negative feedback loop controlling cellular plasticity/EMT governed by p53 | PDF (909.2 KB)
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The shark in us: Learning about the evolution of the p53 regulatory circuit
Rachael Rutkowski & Anton Gartner
Page: 216
Published online: 15 Jan 2012
AbstractforThe shark in us: Learning about the evolution of the p53 regulatory circuit | PDF (909.2 KB)
  • 371 Views
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Mutant p53 subverts PLK2 function in a novel, reinforced loop of corruption
Sue Haupt & Ygal Haupt
Pages: 217-218
Published online: 15 Jan 2012
AbstractforMutant p53 subverts PLK2 function in a novel, reinforced loop of corruption | PDF (1 MB)
  • 330 Views
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Extra Views

The power of MEN in cytokinesis
Franz Meitinger, Saravanan Palani & Gislene Pereira
Pages: 219-228
Published online: 15 Jan 2012
AbstractforThe power of MEN in cytokinesis | PDF (2.3 MB)
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The lesser known story of X chromosome reactivation
A closer look into the reprogramming of the inactive X chromosome
Eriona Hysolli, Yoshiaki Tanaka, Kun-Yong Kim, Yong Wook Jung & In-Hyun Park
Pages: 229-235
Published online: 15 Jan 2012
AbstractforThe lesser known story of X chromosome reactivation | Full Text | References | PDF (574.8 KB)
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Deconvoluting mTOR biology
Jason D. Weber & David H. Gutmann
Pages: 236-248
Published online: 15 Jan 2012
AbstractforDeconvoluting mTOR biology | Full Text | References | PDF (1.7 MB)
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What makes the engine hum
Rad6, a cell cycle supercharger
Jorrit M. Enserink & Richard D. Kolodner
Pages: 249-252
Published online: 15 Jan 2012
AbstractforWhat makes the engine hum | Full Text | References | PDF (392.5 KB)
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Perspective

Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism
In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism
Adam Ertel, Aristotelis Tsirigos, Diana Whitaker-Menezes, Ruth Birbe, Stephanos Pavlides, Ubaldo E. Martinez-Outschoorn, Richard G. Pestell, Anthony Howell, Federica Sotgia & Michael P. Lisanti
Pages: 253-263
Published online: 15 Jan 2012
AbstractforIs cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism | Full Text | References | PDF (3.8 MB) | Supplemental
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Review

Review Article
Fine-tuning of the intracellular canonical Notch signaling pathway
Tilman Borggrefe & Robert Liefke
Pages: 264-276
Published online: 15 Jan 2012
AbstractforFine-tuning of the intracellular canonical Notch signaling pathway | PDF (1.4 MB) | Supplemental
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Report

Article
Differential stimulation of hepatitis C virus RNA translation by microRNA-122 in different cell cycle phases
Carmen Fehr, K. Dominik Conrad & Michael Niepmann
Pages: 277-285
Published online: 15 Jan 2012
AbstractforDifferential stimulation of hepatitis C virus RNA translation by microRNA-122 in different cell cycle phases | Full Text | References | PDF (826.4 KB)
  • 686 Views
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Article
The BRAFV600E causes widespread alterations in gene methylation in the genome of melanoma cells
Peng Hou, Dingxie Liu, Jianli Dong & Mingzhao Xing
Pages: 286-295
Published online: 15 Jan 2012
AbstractforThe BRAFV600E causes widespread alterations in gene methylation in the genome of melanoma cells | Full Text | References | PDF (4.3 MB) | Supplemental
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Article
A functional cooperativity between Aurora A kinase and LIM kinase1
Implication in the mitotic process
Lisa Ritchey, Richard Ottman, Michael Roumanos & Ratna Chakrabarti
Pages: 296-309
Published online: 15 Jan 2012
AbstractforA functional cooperativity between Aurora A kinase and LIM kinase1 | Full Text | References | PDF (2.5 MB) | Supplemental
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Article
Monitoring APC/C activity in the presence of chromosomal misalignment in unperturbed cell populations
Dominik Schnerch, Marie Follo, Julika Krohs, Julia Felthaus, Monika Engelhardt & Ralph Wäsch
Pages: 310-321
Published online: 15 Jan 2012
AbstractforMonitoring APC/C activity in the presence of chromosomal misalignment in unperturbed cell populations | PDF (5.5 MB) | Supplemental
  • 397 Views
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Article
Interaction between ZBP-89 and p53 mutants and its contribution to effects of HDACi on hepatocellular carcinoma
Chris Z.Y. Zhang, George G. Chen, Juanita L. Merchant & Paul B.S. Lai
Pages: 322-334
Published online: 15 Jan 2012
AbstractforInteraction between ZBP-89 and p53 mutants and its contribution to effects of HDACi on hepatocellular carcinoma | Full Text | References | PDF (3 MB)
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Article
Combined effect of cyclin D3 expression and abrogation of cyclin D1 prevent mouse skin tumor development
Xian Wang, Christopher Sistrunk, Paula L. Miliani de Marval, Yongbaek Kim & Marcelo L. Rodriguez-Puebla
Pages: 335-342
Published online: 15 Jan 2012
AbstractforCombined effect of cyclin D3 expression and abrogation of cyclin D1 prevent mouse skin tumor development | Full Text | References | PDF (802.3 KB)
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Article
Aging reverses the role of the transient receptor potential vanilloid-1 channel in systemic inflammation from anti-inflammatory to proinflammatory
Samuel P. Wanner, Andras Garami, Eszter Pakai, Daniela L. Oliveira, Narender R. Gavva, Cândido C. Coimbra & Andrej A. Romanovsky
Pages: 343-349
Published online: 15 Jan 2012
AbstractforAging reverses the role of the transient receptor potential vanilloid-1 channel in systemic inflammation from anti-inflammatory to proinflammatory | Full Text | References | PDF (606.3 KB)
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Article
Entrainment of breast (cancer) epithelial cells detects distinct circadian oscillation patterns for clock and hormone receptor genes
Stefano Rossetti, Joseph Esposito, Francesca Corlazzoli, Alex Gregorski & Nicoletta Sacchi
Pages: 350-360
Published online: 15 Jan 2012
AbstractforEntrainment of breast (cancer) epithelial cells detects distinct circadian oscillation patterns for clock and hormone receptor genes | Full Text | References | PDF (2.1 MB)
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Article
KRAS alleles: The LCS6 3′UTR variant and KRAS coding sequence mutations in the NCI-60 panel
Samrat T. Kundu, Sunitha Nallur, Trupti Paranjape, Marta Boeke, Joanne Barnes Weidhaas & Frank J. Slack
Pages: 361-366
Published online: 15 Jan 2012
AbstractforKRAS alleles: The LCS6 3′UTR variant and KRAS coding sequence mutations in the NCI-60 panel | PDF (404.9 KB) | Supplemental
  • 634 Views
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Article
Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers
Xin-Sheng Deng, Shuiliang Wang, Anlong Deng, Bolin Liu, Susan M. Edgerton, Stuart E. Lind, Reema Wahdan-Alaswad & Ann D. Thor
Pages: 367-376
Published online: 15 Jan 2012
AbstractforMetformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers | PDF (1.6 MB) | Supplemental
  • 2743 Views
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Article
Bone marrow- and subcutaneous adipose tissue-derived mesenchymal stem cells: Differences and similarities
Renata I. Dmitrieva, Izida R. Minullina, Anna A. Bilibina, Olga V. Tarasova, Sergey V. Anisimov & Andrey Y. Zaritskey
Pages: 377-383
Published online: 15 Jan 2012
AbstractforBone marrow- and subcutaneous adipose tissue-derived mesenchymal stem cells: Differences and similarities | PDF (611.1 KB)
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Article
Acm1 contributes to nuclear positioning by inhibiting Cdh1-substrate interactions
Juan S. Martinez, Hana Hall, Matthew D. Bartolowits & Mark C. Hall
Pages: 384-394
Published online: 15 Jan 2012
AbstractforAcm1 contributes to nuclear positioning by inhibiting Cdh1-substrate interactions | Full Text | References | PDF (1.5 MB) | Supplemental
  • 597 Views
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Article
Differential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells
A novel therapeutic modality
Alexander Yemelyanov, Pankaj Bhalla, Ximing Yang, Andrey Ugolkov, Kenichi Iwadate, Apollon Karseladze & Irina Budunova
Pages: 395-406
Published online: 15 Jan 2012
AbstractforDifferential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells | Full Text | References | PDF (1.8 MB) | Supplemental
  • 1339 Views
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Article
The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G1 arrest
Richard Bennett, Yu Pan, Jaime Christian, Teng Hui & W. Stratford May Jr.
Pages: 407-417
Published online: 15 Jan 2012
AbstractforThe RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G1 arrest | Full Text | References | PDF (1.5 MB)
  • 1064 Views
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