OncoImmunology, Volume 2, Issue 9 (2013)

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OncoImmunology, Volume 2, Issue 9 (2013)

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Editorial

Editorial
Inhibiting the inhibitors
Checkpoints blockade in solid tumors
Domenico Mavilio & Enrico Lugli
Article: e26535
Published online: 26 Sep 2013
CitationforInhibiting the inhibitors | Full Text | References | PDF (151.8 KB)
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Original Research

Article
Clonal expansion of renal cell carcinoma-infiltrating T lymphocytes
Simone P. Sittig, Tania Køllgaard, Kirsten Grønbæk, Manja Idorn, Jörg Hennenlotter, Arnulf Stenzl, Cecile Gouttefangeas & Per thor Straten
Article: e26014
Published online: 26 Sep 2013
AbstractforClonal expansion of renal cell carcinoma-infiltrating T lymphocytes | PDF (565.2 KB)
  • 383 Views
  • 18 CrossRef citations
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Article
A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes
Alberto L Horenstein, Antonella Chillemi, Gianluca Zaccarello, Santina Bruzzone, Valeria Quarona, Andrea Zito, Sara Serra & Fabio Malavasi
Article: e26246
Published online: 26 Sep 2013
AbstractforA CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes | PDF (1,014.7 KB)
  • 1635 Views
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Open Access
Article
Early onset and enhanced growth of autochthonous mammary carcinomas in C3-deficient Her2/neu transgenic mice
Silvio Bandini, Claudia Curcio, Marco Macagno, Elena Quaglino, Maddalena Arigoni, Stefania Lanzardo, Albana Hysi, Giuseppina Barutello, Lorena Consolino, Dario Livio Longo, Piero Musiani, Guido Forni, Manuela Iezzi & Federica Cavallo
Article: e26137
Published online: 12 Sep 2013
AbstractforEarly onset and enhanced growth of autochthonous mammary carcinomas in C3-deficient Her2/neu transgenic mice | Full Text | References | PDF (1.8 MB) | Supplemental
  • 893 Views
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Open Access
Article
Zinc supplementation is required for the cytotoxic and immunogenic effects of chemotherapy in chemoresistant p53-functionally deficient cells
Mara Cirone, Alessia Garufi, Livia Di Renzo, Marisa Granato, Alberto Faggioni & Gabriella D’Orazi
Article: e26198
Published online: 12 Sep 2013
AbstractforZinc supplementation is required for the cytotoxic and immunogenic effects of chemotherapy in chemoresistant p53-functionally deficient cells | Full Text | References | PDF (621.6 KB)
  • 994 Views
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Article
IL-18-based combinatorial adjuvants promote the intranodal production of CCL19 by NK cells and dendritic cells of cancer patients
Jeffrey L. Wong, Ravikumar Muthuswamy, David L. Bartlett & Pawel Kalinski
Article: e26245
Published online: 12 Sep 2013
AbstractforIL-18-based combinatorial adjuvants promote the intranodal production of CCL19 by NK cells and dendritic cells of cancer patients | PDF (448.9 KB)
  • 383 Views
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Review

Review Article
Trial Watch
Anticancer radioimmunotherapy
Erika Vacchelli, Ilio Vitale, Eric Tartour, Alexander Eggermont, Catherine Sautès-Fridman, Jérôme Galon, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi
Article: e25595
Published online: 03 Jul 2013
AbstractforTrial Watch | Full Text | References | PDF (248.5 KB) | Supplemental
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Open Access
Review Article
Enhancing immunotherapy using chemotherapy and radiation to modify the tumor microenvironment
Michael H Kershaw, Christel Devaud, Liza B John, Jennifer A Westwood & Phillip K Darcy
Article: e25962
Published online: 02 Aug 2013
AbstractforEnhancing immunotherapy using chemotherapy and radiation to modify the tumor microenvironment | Full Text | References | PDF (559.2 KB)
  • 2405 Views
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Review Article
Monitoring NK cell activity in patients with hematological malignancies
Sébastien Viel, Emily Charrier, Antoine Marçais, Paul Rouzaire, Jacques Bienvenu, Lionel Karlin, Gilles Salles & Thierry Walzer
Article: e26011
Published online: 12 Sep 2013
AbstractforMonitoring NK cell activity in patients with hematological malignancies | Full Text | References | PDF (299.6 KB)
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Review Article
Strategies to improve the immunogenicity of anticancer vaccines based on dendritic cell/malignant cell fusions
shigeo koido, Sadamu Homma, Masato Okamoto, Yoshihisa Namiki, Kazuki Takakura, Kan Uchiyama, Mikio Kajihara, Seiji Arihiro, Hiroo Imazu, Hiroshi Arakawa, Shin Kan, Hideo Komita, Yuko Kamata, Masaki Ito, Toshifumi Ohkusa, Jianlin Gong & Hisao Tajiri
Article: e25994
Published online: 12 Sep 2013
AbstractforStrategies to improve the immunogenicity of anticancer vaccines based on dendritic cell/malignant cell fusions | PDF (529.5 KB)
  • 280 Views
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Author's View

Continuous 4–1BB co-stimulatory signals for the optimal expansion of tumor-infiltrating lymphocytes for adoptive T-cell therapy
Jessica Ann Chacon, Shari Pilon-Thomas, Amod A Sarnaik & Laszlo G Radvanyi
Article: e25581
Published online: 03 Jul 2013
AbstractforContinuous 4–1BB co-stimulatory signals for the optimal expansion of tumor-infiltrating lymphocytes for adoptive T-cell therapy | Full Text | References | PDF (307 KB)
  • 951 Views
  • 18 CrossRef citations
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Open Access
Cancer-associated fibroblasts and macrophages
Friendly conspirators for malignancy
Paola Chiarugi
Article: e25563
Published online: 03 Jul 2013
AbstractforCancer-associated fibroblasts and macrophages | Full Text | References | PDF (438.1 KB)
  • 918 Views
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Open Access
Identification of new prognostic biomarkers for Stage III metastatic melanoma patients
Hojabr Kakavand, Richard A Scolyer, John F Thompson & Graham J Mann
Article: e25564
Published online: 03 Jul 2013
AbstractforIdentification of new prognostic biomarkers for Stage III metastatic melanoma patients | Full Text | References | PDF (173.1 KB)
  • 500 Views
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Open Access
Contribution of regulatory T cells to immunosuppression and disease progression in multiple myeloma patients
Karthick Raja Muthu Raja & Roman Hajek
Article: e25619
Published online: 09 Jul 2013
AbstractforContribution of regulatory T cells to immunosuppression and disease progression in multiple myeloma patients | Full Text | References | PDF (252.5 KB)
  • 743 Views
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Open Access
Zoledronate-pulsed dendritic cell-based anticancer vaccines
Takashi Kamigaki, Masashi Takahara, Ryuji Maekawa & Shigenori Goto
Article: e25636
Published online: 09 Jul 2013
AbstractforZoledronate-pulsed dendritic cell-based anticancer vaccines | Full Text | References | PDF (226.3 KB)
  • 577 Views
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Mutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus
Todd C Hollon, Richard L Price, Chang-Hyuk Kwon & E Antonio Chiocca
Article: e25620
Published online: 09 Jul 2013
AbstractforMutations in glioblastoma oncosuppressive pathways pave the way for oncomodulatory activity of cytomegalovirus | Full Text | References | PDF (320.5 KB)
  • 533 Views
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Open Access
Radiation-induced tumor dormancy reflects an equilibrium between the proliferation and T lymphocyte-mediated death of malignant cells
Hua Liang, Liufu Deng, Byron Burnette, Ralph R Weichselbaum & Yang-Xin Fu
Article: e25668
Published online: 09 Jul 2013
AbstractforRadiation-induced tumor dormancy reflects an equilibrium between the proliferation and T lymphocyte-mediated death of malignant cells | Full Text | References | PDF (242.5 KB)
  • 969 Views
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Open Access
CX3CL1 at the crossroad of EGF signals
Relevance for the progression of ERBB2+ breast carcinoma
Manuel Tardáguila & Santos Mañes
Article: e25669
Published online: 09 Jul 2013
AbstractforCX3CL1 at the crossroad of EGF signals | Full Text | References | PDF (393.1 KB)
  • 501 Views
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Open Access
RON promotes the metastatic spread of breast carcinomas by subverting antitumor immune responses
Henok Eyob, Huseyin Atakan Ekiz & Alana L Welm
Article: e25670
Published online: 14 Aug 2013
AbstractforRON promotes the metastatic spread of breast carcinomas by subverting antitumor immune responses | Full Text | References | PDF (255.1 KB)
  • 840 Views
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Open Access
Overcoming immunosuppression as a new immunotherapeutic approach against pancreatic cancer
Alexandr V Bazhin, Jagadeesh Bayry, Viktor Umansky, Jens Werner & Svetlana Karakhanova
Article: e25736
Published online: 23 Jul 2013
AbstractforOvercoming immunosuppression as a new immunotherapeutic approach against pancreatic cancer | Full Text | References | PDF (224.9 KB)
  • 690 Views
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Immune ambivalence
The schizophrenic bleomycin
Grégoire Mignot, Hélène Bugaut & François Ghiringhelli
Article: e25737
Published online: 23 Jul 2013
AbstractforImmune ambivalence | Full Text | References | PDF (140.7 KB)
  • 509 Views
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Open Access
Inhibition of the mevalonate pathway to override chemoresistance and promote the immunogenic demise of cancer cells
Killing two birds with one stone
Chiara Riganti & Massimo Massaia
Article: e25770
Published online: 29 Jul 2013
AbstractforInhibition of the mevalonate pathway to override chemoresistance and promote the immunogenic demise of cancer cells | Full Text | References | PDF (406.4 KB)
  • 881 Views
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Getting by with a little help from the right CD4+ T cells
Sabine Hoepner & Paul R Walker
Article: e25772
Published online: 29 Jul 2013
AbstractforGetting by with a little help from the right CD4+ T cells | Full Text | References | PDF (375 KB)
  • 415 Views
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Improving macrophage responses to therapeutic antibodies by molecular engineering of SIRPα variants
Kipp Weiskopf, Aaron M Ring, Peter J Schnorr, Jens-Peter Volkmer, Anne Kathrin Volkmer, Irving L Weissman & K Christopher Garcia
Article: e25773
Published online: 29 Jul 2013
AbstractforImproving macrophage responses to therapeutic antibodies by molecular engineering of SIRPα variants | Full Text | References | PDF (209.2 KB)
  • 1532 Views
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The Janus face of cyclophosphamide
A sterile inflammatory response that potentiates cancer immunotherapy
Giovanna Ziccheddu, Enrico Proietti & Federica Moschella
Article: e25789
Published online: 29 Jul 2013
AbstractforThe Janus face of cyclophosphamide | Full Text | References | PDF (283.1 KB)
  • 646 Views
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BTLA, a key regulator of Vγ9Vδ2 T-cell proliferation
Julie Gertner-Dardenne, Cyril Fauriat & Daniel Olive
Article: e25853
Published online: 29 Jul 2013
AbstractforBTLA, a key regulator of Vγ9Vδ2 T-cell proliferation | Full Text | References | PDF (218.6 KB)
  • 659 Views
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Long peptide-based cancer immunotherapy targeting tumor antigen-specific CD4+ and CD8+ T cells
Yusuke Tomita & Yasuharu Nishimura
Article: e25801
Published online: 29 Jul 2013
AbstractforLong peptide-based cancer immunotherapy targeting tumor antigen-specific CD4+ and CD8+ T cells | Full Text | References | PDF (326.1 KB)
  • 713 Views
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Regulation of NKG2D signaling during the epithelial-to-mesenchymal transition
Alejandro López-Soto, Leticia Huergo Zapico, Andrea Acebes-Huerta, Luis Rodrigo & Segundo Gonzalez
Article: e25820
Published online: 29 Jul 2013
AbstractforRegulation of NKG2D signaling during the epithelial-to-mesenchymal transition | Full Text | References | PDF (340 KB)
  • 556 Views
  • 11 CrossRef citations
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The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma
Wen-Wei Sung & Huei Lee
Article: e25854
Published online: 29 Jul 2013
AbstractforThe role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma | Full Text | References | PDF (187.8 KB)
  • 661 Views
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Combining conventional chemotherapy and γδ T cell-based immunotherapy to target cancer-initiating cells
Matilde Todaro, Serena Meraviglia, Nadia Caccamo, Giorgio Stassi & Francesco Dieli
Article: e25821
Published online: 29 Jul 2013
AbstractforCombining conventional chemotherapy and γδ T cell-based immunotherapy to target cancer-initiating cells | Full Text | References | PDF (195.5 KB)
  • 713 Views
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