Advanced search
Publication Cover
International Journal of Hyperthermia Volume 20, 2004 - Issue 2: Radiosensitization by hyperthermia: Mechanisms and clinical Implications
Submit an article Journal homepage
277
Views
79
CrossRef citations to date
0
Altmetric
Original Article

Mechanism of radiosensitization by hyperthermia (43°C) as derived from studies with DNA repair defective mutant cell lines

H. H. Kampinga Department of Radiation and Stress Cell Biology, University of Groningen, A Deusinglaan 1, 9713 AV, Groningen, The NetherlandsCorrespondence[email protected]
,
J. R. Dynlacht Department of Radiation Oncology and Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
&
E. Dikomey Institute of Biophysics and Radiobiology, University of Hamburg, Martinistr. 52, 20246 Hamburg, Germany
Pages 131-139 | Received 11 May 2003, Accepted 15 Sep 2003, Published online: 09 Jul 2009

Citations (79)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (19)

Di Xu, Wen-Juan Tang, Yi-Zhi Zhu, Zhen Liu, Kai Yang, Ming-Xing Liang, Xiu Chen, Yang Wu, Jin-Hai Tang & Wei Zhang. (2022) Hyperthermia promotes exosome secretion by regulating Rab7b while increasing drug sensitivity in adriamycin-resistant breast cancer. International Journal of Hyperthermia 39:1, pages 246-257.
Read now
Felista L. Tansi, Wisdom O. Maduabuchi, Melanie Hirsch, Paul Southern, Simon Hattersley, Rainer Quaas, Ulf Teichgräber, Quentin A. Pankhurst & Ingrid Hilger. (2021) Deep-tissue localization of magnetic field hyperthermia using pulse sequencing. International Journal of Hyperthermia 38:1, pages 743-754.
Read now
Arlene L. Oei, Vidhula R. Ahire, C. M. van Leeuwen, Rosemarie ten Cate, Lukas J. A. Stalpers, Johannes Crezee, H. Petra Kok & Nicolaas A. P. Franken. (2018) Enhancing radiosensitisation of BRCA2-proficient and BRCA2-deficient cell lines with hyperthermia and PARP1-i. International Journal of Hyperthermia 34:1, pages 39-48.
Read now
C. M. van Leeuwen, A. L. Oei, R. ten Cate, N. A. P. Franken, A. Bel, L. J. A. Stalpers, J. Crezee & H. P. Kok. (2018) Measurement and analysis of the impact of time-interval, temperature and radiation dose on tumour cell survival and its application in thermoradiotherapy plan evaluation. International Journal of Hyperthermia 34:1, pages 30-38.
Read now
A. L. Oei, L. E. M. Vriend, P. M. Krawczyk, M. R. Horsman, N. A. P. Franken & J. Crezee. (2017) Targeting therapy-resistant cancer stem cells by hyperthermia. International Journal of Hyperthermia 33:4, pages 419-427.
Read now
Hans Crezee, Caspar M. van Leeuwen, Arlene L. Oei, Lukas J.A. Stalpers, Arjan Bel, Nicolaas A. Franken & H. Petra Kok. (2016) Thermoradiotherapy planning: Integration in routine clinical practice. International Journal of Hyperthermia 32:1, pages 41-49.
Read now
Vladimir V. Kosterev, Evgeny A. Kramer-Ageev, Vladimir N. Mazokhin, Gerard C. van Rhoon & Johannes Crezee. (2015) Development of a novel method to enhance the therapeutic effect on tumours by simultaneous action of radiation and heating. International Journal of Hyperthermia 31:4, pages 443-452.
Read now
Silvina B. Nadin, F. Darío Cuello-Carrión, Mayra L. Sottile, Daniel R. Ciocca & Laura M. Vargas-Roig. (2012) Effects of hyperthermia on Hsp27 (HSPB1), Hsp72 (HSPA1A) and DNA repair proteins hMLH1 and hMSH2 in human colorectal cancer hMLH1-deficient and hMLH1-proficient cell lines. International Journal of Hyperthermia 28:3, pages 191-201.
Read now
Joseph L. Roti Roti, Raj K. Pandita, Jason D. Mueller, Peter Novak, Eduardo G. Moros & Andrei Laszlo. (2010) Severe, short-duration (0–3 min) heat shocks (50–52°C) inhibit the repair of DNA damage. International Journal of Hyperthermia 26:1, pages 67-78.
Read now
P. Gabriele, T. Ferrara, B. Baiotto, E. Garibaldi, P.G. Marini, G. Penduzzu, V. Giovannini, F. Bardati & C. Guiot. (2009) Radio hyperthermia for re-treatment of superficial tumours. International Journal of Hyperthermia 25:3, pages 189-198.
Read now
Andrei Laszlo & Ilona Fleischer. (2009) The heat-induced γ-H2AX response does not play a role in hyperthermic cell killing. International Journal of Hyperthermia 25:3, pages 199-209.
Read now
José A. Peñagarícano, Eduardo Moros, Petr Novák, Yulong Yan & Peter Corry. (2008) Feasibility of concurrent treatment with the scanning ultrasound reflector linear array system (SURLAS) and the helical tomotherapy system. International Journal of Hyperthermia 24:5, pages 377-388.
Read now
George Iliakis, Wenqi Wu & Minli Wang. (2008) DNA double strand break repair inhibition as a cause of heat radiosensitization: Re-evaluation considering backup pathways of NHEJ. International Journal of Hyperthermia 24:1, pages 17-29.
Read now
Joseph L. Roti Roti. (2008) Cellular responses to hyperthermia (40–46°C): Cell killing and molecular events. International Journal of Hyperthermia 24:1, pages 3-15.
Read now
M. Xu, R. J. Myerson, Y. Xia, T. Whitehead, E. G. Moros, W. L. Straube & J. L. Roti Roti. (2007) The effects of 41°C hyperthermia on the DNA repair protein, MRE11, correlate with radiosensitization in four human tumor cell lines. International Journal of Hyperthermia 23:4, pages 343-351.
Read now
J. W. J. Bergs, N. A. P. Franken, J. Haveman, E. D. Geijsen, J. Crezee & C. van Bree. (2007) Hyperthermia, cisplatin and radiation trimodality treatment: A promising cancer treatment? A review from preclinical studies to clinical application. International Journal of Hyperthermia 23:4, pages 329-341.
Read now
Joseph L. Roti Roti. (2007) Heat-induced alterations of nuclear protein associations and their effects on DNA repair and replication. International Journal of Hyperthermia 23:1, pages 3-15.
Read now
Bert Hildebrandt, Dagmar Schoeler, Bert Hildebrandt, Dagmar Schoeler, Frauke Ringel, Thoralf Kerner, Peter Wust, Hanno Riess & Folke Schriever. (2006) Differential gene expression in peripheral blood lymphocytes of cancer patients treated with whole body hyperthermia and chemotherapy: A pilot study. International Journal of Hyperthermia 22:8, pages 625-635.
Read now
Harm H. Kampinga. (2006) Cell biological effects of hyperthermia alone or combined with radiation or drugs: A short introduction to newcomers in the field. International Journal of Hyperthermia 22:3, pages 191-196.
Read now

Articles from other publishers (60)

Rosa Orlacchio, Yann Le Page, Yves Le Dréan & Maxim Zhadobov. (2023) Millimeter-Wave Pulsed Heating in Vitro: Effect of Pulse Duration. IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology 7:2, pages 136-143.
Crossref
Juan Beltran-Huarac, Dina N. Yamaleyeva, Gianpietro Dotti, Shawn Hingtgen, Marina Sokolsky-Papkov & Alexander V. Kabanov. (2023) Magnetic Control of Protein Expression via Magneto-mechanical Actuation of ND-PEGylated Iron Oxide Nanocubes for Cell Therapy. ACS Applied Materials & Interfaces 15:16, pages 19877-19891.
Crossref
Mansoureh Hashemi, Aida abbasiazam, Saeed Oraee-Yazdani & Janice Lenzer. (2022) Response of human glioblastoma cells to hyperthermia: Cellular apoptosis and molecular events. Tissue and Cell 75, pages 101751.
Crossref
Rosa Orlacchio, Denys Nikolayev, Yann Le Page, Yves Le Drean & Maxim Zhadobov. (2022) Millimeter-Wave Heating In Vitro: Local Microscale Temperature Measurements Correlated to Heat Shock Cellular Response . IEEE Transactions on Biomedical Engineering 69:2, pages 840-848.
Crossref
Adela Ademaj, Danai P. Veltsista, Pirus Ghadjar, Dietmar Marder, Eva Oberacker, Oliver J. Ott, Peter Wust, Emsad Puric, Roger A. Hälg, Susanne Rogers, Stephan Bodis, Rainer Fietkau, Hans Crezee & Oliver Riesterer. (2022) Clinical Evidence for Thermometric Parameters to Guide Hyperthermia Treatment. Cancers 14:3, pages 625.
Crossref
Somya Ranjan Dash & Chanakya Nath Kundu. (2022) Photothermal Therapy: A New Approach to Eradicate Cancer. Current Nanoscience 18:1, pages 31-47.
Crossref
Sabine Oldenborg & Jean-Michel Hannoun-Levi. 2022. Breast Cancer Radiation Therapy. Breast Cancer Radiation Therapy 413 419 .
Kaitlyn Melnick, David Shin, Farhad Dastmalchi, Zain Kabeer, Maryam Rahman, David Tran & Ashley Ghiaseddin. (2021) Role of Laser Interstitial Thermal Therapy in the Management of Primary and Metastatic Brain Tumors. Current Treatment Options in Oncology 22:12.
Crossref
Gary Hannon, Felista L. Tansi, Ingrid Hilger & Adriele Prina‐Mello. (2021) The Effects of Localized Heat on the Hallmarks of Cancer. Advanced Therapeutics 4:7.
Crossref
Jaber Beik, Zahra Alamzadeh, Mehri Mirrahimi, Abolfazl Sarikhani, Tahereh Shakerian Ardakani, Mohamadreza Asadi, Rasoul Irajirad, Mehraban Mirrahimi, Vahid Pirhajati Mahabadi, Neda Eslahi, Jeff W.M. Bulte, Habib Ghaznavi & Ali Shakeri-Zadeh. (2021) Multifunctional Theranostic Graphene Oxide Nanoflakes as MR Imaging Agents with Enhanced Photothermal and Radiosensitizing Properties. ACS Applied Bio Materials 4:5, pages 4280-4291.
Crossref
Vandana Singh, Pegah Johansson, Dmitry Torchinsky, Yii-Lih Lin, Robin Öz, Yuval Ebenstein, Ola Hammarsten & Fredrik Westerlund. (2020) Quantifying DNA damage induced by ionizing radiation and hyperthermia using single DNA molecule imaging. Translational Oncology 13:10, pages 100822.
Crossref
Mehri Mirrahimi, Jaber Beik, Mehraban Mirrahimi, Zahra Alamzadeh, Samaneh Teymouri, Vahid Pirhajati Mahabadi, Neda Eslahi, Fatemeh Ebrahimi Tazehmahalleh, Habib Ghaznavi, Ali Shakeri-Zadeh & Christos Moustakis. (2020) Triple combination of heat, drug and radiation using alginate hydrogel co-loaded with gold nanoparticles and cisplatin for locally synergistic cancer therapy. International Journal of Biological Macromolecules 158, pages 617-626.
Crossref
Artem V. Luzhin, Bogdan Avanesyan, Artem K. Velichko, Victoria O. Shender, Natalia Ovsyannikova, Georgij P. Arapidi, Polina V. Shnaider, Nadezhda V. Petrova, Igor I. Kireev, Sergey V. Razin & Omar L. Kantidze. (2020) Chromatin Trapping of Factors Involved in DNA Replication and Repair Underlies Heat-Induced Radio- and Chemosensitization. Cells 9:6, pages 1423.
Crossref
Zahra Alamzadeh, Jaber Beik, Mehraban Mirrahimi, Ali Shakeri-Zadeh, Fatemeh Ebrahimi, Ali Komeili, Behafarid Ghalandari, Habib Ghaznavi, S. Kamran Kamrava & Christos Moustakis. (2020) Gold nanoparticles promote a multimodal synergistic cancer therapy strategy by co-delivery of thermo-chemo-radio therapy. European Journal of Pharmaceutical Sciences 145, pages 105235.
Crossref
Rosa Orlacchio, Yann Le Page, Yves Le Dréan, Rémy Le Guével, Ronan Sauleau, Stanislav Alekseev & Maxim Zhadobov. (2019) Millimeter-wave pulsed heating in vitro: cell mortality and heat shock response. Scientific Reports 9:1.
Crossref
Jaber Beik, Maziar Khateri, Zohreh Khosravi, S. Kamran Kamrava, Siavash Kooranifar, Habib Ghaznavi & Ali Shakeri-Zadeh. (2019) Gold nanoparticles in combinatorial cancer therapy strategies. Coordination Chemistry Reviews 387, pages 299-324.
Crossref
Baofeng Ma, Xiaoming Liu & Zhaoxiao Yu. (2019) The effect of high intensity focused ultrasound on the treatment of liver cancer and patients’ immunity. Cancer Biomarkers 24:1, pages 85-90.
Crossref
Yang Wu, Wei Zhang, Di Xu, Li Ding, Rong Ma, Jian-Zhong Wu & Jin-Hai Tang. (2018) A novel Met-IR-782 near-infrared probe for fluorescent imaging-guided photothermal therapy in breast cancer. Lasers in Medical Science 33:7, pages 1601-1608.
Crossref
David Chang, May Lim, Jeroen A. C. M. Goos, Ruirui Qiao, Yun Yee Ng, Friederike M. Mansfeld, Michael Jackson, Thomas P. Davis & Maria Kavallaris. (2018) Biologically Targeted Magnetic Hyperthermia: Potential and Limitations. Frontiers in Pharmacology 9.
Crossref
Huan Zhang, Xiao Li Liu, Yi Fan Zhang, Fei Gao, Ga Long Li, Yuan He, Ming Li Peng & Hai Ming Fan. (2018) Magnetic nanoparticles based cancer therapy: current status and applications. Science China Life Sciences 61:4, pages 400-414.
Crossref
O. Kaidar-Person, S. Oldenborg & P. Poortmans. (2018) Re-irradiation and Hyperthermia in Breast Cancer. Clinical Oncology 30:2, pages 73-84.
Crossref
KEN OHNISHI. (2017) Effectiveness of Hyperthermia on Cancer Stem Cells. Thermal Medicine 33:2, pages 29-37.
Crossref
Sheetal Jha, Pramod Kumar Sharma & Rishabha Malviya. (2016) Hyperthermia: Role and Risk Factor for Cancer Treatment. Achievements in the Life Sciences 10:2, pages 161-167.
Crossref
JUDITH W.J. BERGS, ARLENE L. OEI, ROSEMARIE TEN CATE, HANS M. RODERMOND, LUKAS J. STALPERS, GERRIT W. BARENDSEN & NICOLAAS A.P. FRANKEN. (2016) Dynamics of chromosomal aberrations, induction of apoptosis, BRCA2 degradation and sensitization to radiation by hyperthermia. International Journal of Molecular Medicine 38:1, pages 243-250.
Crossref
Theodora Mantso, George Goussetis, Rodrigo Franco, Sotiris Botaitis, Aglaia Pappa & Mihalis Panayiotidis. (2016) Effects of hyperthermia as a mitigation strategy in DNA damage-based cancer therapies. Seminars in Cancer Biology 37-38, pages 96-105.
Crossref
Erik A. Bey, Julia C. Meade, Molly A. Silvers, Edward A. Motea, Praveen L. Patidar, Rolf Brekken, Stanislaw Deja, Matthew E. Merritt, Jessica A. Kilgore, Yuliang Liu, Xiumei Huang, Longshan Li, John Yordy, Noelle S. Williams, Jinming Gao & David A. Boothman. 2016. Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment. Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment 225 252 .
Divya Bijukumar, C. M. Girish, Abhilash Sasidharan, Shantikumar Nair & Manzoor Koyakutty. (2015) Transferrin-Conjugated Biodegradable Graphene for Targeted Radiofrequency Ablation of Hepatocellular Carcinoma. ACS Biomaterials Science & Engineering 1:12, pages 1211-1219.
Crossref
David Robert Grimes & Mike Partridge. (2015) A mechanistic investigation of the oxygen fixation hypothesis and oxygen enhancement ratio. Biomedical Physics & Engineering Express 1:4, pages 045209.
Crossref
Arlene L. Oei, Lianne E. M. Vriend, Johannes Crezee, Nicolaas A. P. Franken & Przemek M. Krawczyk. (2015) Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all. Radiation Oncology 10:1.
Crossref
N.R. Datta, S. Gómez Ordóñez, U.S. Gaipl, M.M. Paulides, H. Crezee, J. Gellermann, D. Marder, E. Puric & S. Bodis. (2015) Local hyperthermia combined with radiotherapy and-/or chemotherapy: Recent advances and promises for the future. Cancer Treatment Reviews 41:9, pages 742-753.
Crossref
Kirsten Lauber, Nikko Brix, Anne Ernst, Roman Hennel, Julia Krombach, Heike Anders & Claus Belka. (2015) Targeting the heat shock response in combination with radiotherapy: Sensitizing cancer cells to irradiation-induced cell death and heating up their immunogenicity. Cancer Letters 368:2, pages 209-229.
Crossref
Małgorzata Krajewska, Rudolf S. N. Fehrmann, Elisabeth G. E. de Vries & Marcel A. T. M. van Vugt. (2015) Regulators of homologous recombination repair as novel targets for cancer treatment. Frontiers in Genetics 6.
Crossref
Clarissa Amaya, Vittal Kurisetty, Jessica Stiles, Alice M Nyakeriga, Arunkumar Arumugam, Rajkumar Lakshmanaswamy, Cristian E Botez, Dianne C Mitchell & Brad A Bryan. (2014) A genomics approach to identify susceptibilities of breast cancer cells to “fever-range” hyperthermia. BMC Cancer 14:1.
Crossref
Cem Terzi. (2014) Peritoneal carcinomatosis of gastrointestinal tumors: Where are we now?. World Journal of Gastroenterology 20:39, pages 14371.
Crossref
Artem K. Velichko, Elena N. Markova, Nadezhda V. Petrova, Sergey V. Razin & Omar L. Kantidze. (2013) Mechanisms of heat shock response in mammals. Cellular and Molecular Life Sciences 70:22, pages 4229-4241.
Crossref
Ling-Yun Zhao, Jia-Yi Liu, Wei-Wei Ouyang, Dan-Ye Li, Li Li, Li-Ya Li & Jin-Tian Tang. (2013) Magnetic-mediated hyperthermia for cancer treatment: Research progress and clinical trials. Chinese Physics B 22:10, pages 108104.
Crossref
Stefan C. Genet, Yoshihiro Fujii, Junko Maeda, Masami Kaneko, Matthew D. Genet, Kiyoshi Miyagawa & Takamitsu A. Kato. (2013) Hyperthermia inhibits homologous recombination repair and sensitizes cells to ionizing radiation in a time- and temperature-dependent manner. Journal of Cellular Physiology 228:7, pages 1473-1481.
Crossref
Gyula P. Szigeti, Gabriella Hegyi & Olivér Szasz. (2013) Hyperthermia versus Oncothermia: Cellular Effects in Cancer Therapy. Conference Papers in Medicine 2013, pages 1-4.
Crossref
Damiano Fantini, Eva Moritz, Frédéric Auvré, Rachel Amouroux, Anna Campalans, Bernd Epe, Anne Bravard & J. Pablo Radicella. (2013) Rapid inactivation and proteasome-mediated degradation of OGG1 contribute to the synergistic effect of hyperthermia on genotoxic treatments. DNA Repair 12:3, pages 227-237.
Crossref
Gabriella Hegyi, Gyula P. Szigeti & András Szász. (2013) Hyperthermia versus Oncothermia: Cellular Effects in Complementary Cancer Therapy. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-12.
Crossref
Brian E. Caffrey, Tom A. Williams, Xiaowei Jiang, Christina Toft, Karsten Hokamp & Mario A. Fares. (2012) Proteome-Wide Analysis of Functional Divergence in Bacteria: Exploring a Host of Ecological Adaptations. PLoS ONE 7:4, pages e35659.
Crossref
G. Vogin. (2011) Radiosensibilité, radiocurabilité et réparation. Cancer/Radiothérapie 15:4, pages 294-306.
Crossref
Joseph R. Dynlacht, Christopher N. Batuello, Jennifer T. Lopez, Kyung Keun Kim & John J. Turchi. (2011) Identification of Mre11 as a Target for Heat Radiosensitization. Radiation Research 176:3, pages 323.
Crossref
Przemek M. KrawczykBerina EppinkJeroen Essers, Jan StapHans RodermondHanny OdijkAlex ZelenskyChris van BreeLukas J. Stalpers, Marrije R. BuistThomas Soullié, Joost Rens, Hence J. M. Verhagen, Mark J. O'Connor, Nicolaas A. P. Franken, Timo L. M. ten Hagen, Roland KanaarJacob A. Aten. (2011) Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition. Proceedings of the National Academy of Sciences 108:24, pages 9851-9856.
Crossref
Joseph L. Roti Roti, Robert P. VanderWaal & Andrei Laszlo. 2011. Molecular Determinants of Radiation Response. Molecular Determinants of Radiation Response 227 249 .
Mario Palazzi, Sergio Maluta, Stefano Dall'Oglio & Mario Romano. (2018) The role of hyperthermia in the battle against cancer. Tumori Journal 96:6, pages 902-910.
Crossref
Bogdan I. Gerashchenko, Gerirose Gooding & Joseph R. Dynlacht. (2010) Hyperthermia alters the interaction of proteins of the Mre11 complex in irradiated cells. Cytometry Part A 77A:10, pages 940-952.
Crossref
Robert P. Vanderwaal, Leonard B. MaggiJr.Jr., Jason D. Weber, Clayton R. Hunt & Joseph L. Roti Roti. (2009) Nucleophosmin Redistribution following Heat Shock: A Role in Heat-Induced Radiosensitization. Cancer Research 69:16, pages 6454-6462.
Crossref
Andrei Laszlo & Ilona Fleischer. (2009) Heat-Induced Perturbations of DNA Damage Signaling Pathways are Modulated by Molecular Chaperones. Cancer Research 69:5, pages 2042-2049.
Crossref
Petr Novák, José A Peñagarícano, Volodymyr Nahirnyak, Peter Corry & Eduardo G Moros. (2008) Influence of the SURLAS applicator on radiation dose distributions during simultaneous thermoradiotherapy with helical tomotherapy. Physics in Medicine and Biology 53:10, pages 2509-2522.
Crossref
KANWAL AHMED, TAKESHI HORI, DA-YONG YU, ZHENG-LI WEI, QING-LI ZHAO, MASAO NAKASHIMA, MARIAME ALI HASSAN & TAKASHI KONDO. (2008) Hyperthermia Chemo-sensitization, Chemical Thermo-sensitization and Apoptosis. Thermal Medicine 24:1, pages 1-12.
Crossref
Judith W. J. BERGS, Rosemarie ten CATE, Jaap HAVEMAN, Jan Paul MEDEMA, Nicolaas A. P. FRANKEN & Chris van BREE. (2008) Chromosome Fragments have the Potential to Predict Hyperthermia-induced Radio-sensitization in Two Different Human Tumor Cell Lines. Journal of Radiation Research 49:5, pages 465-472.
Crossref
Riadh Habash. 2007. Bioeffects and Therapeutic Applications of Electromagnetic Energy. Bioeffects and Therapeutic Applications of Electromagnetic Energy 199 220 .
Maryline Moulin, Stéphane Carpentier, Thierry Levade & André-Patrick Arrigo. (2007) Potential roles of membrane fluidity and ceramide in hyperthermia and alcohol stimulation of TRAIL apoptosis. Apoptosis 12:9, pages 1703-1720.
Crossref
Annette Dieing, Olaf Ahlers, Bert Hildebrandt, Thoralf Kerner, Ingo Tamm, Kurt Possinger & Peter Wust. 2007. Neurobiology of Hyperthermia. Neurobiology of Hyperthermia 137 152 .
Valeria Milani & Elfriede Noessner. (2005) Effects of thermal stress on tumor antigenicity and recognition by immune effector cells. Cancer Immunology, Immunotherapy 55:3, pages 312-319.
Crossref
Ingrid Hilger, Alexander Rapp, Karl-Otto Greulich & Werner Alois Kaiser. (2005) Assessment of DNA Damage in Target Tumor Cells after Thermoablation in Mice. Radiology 237:2, pages 500-506.
Crossref
G.P. Raaphorst, J.M. LeBlanc, L.F. Li & D.P. Yang. (2005) Hyperthermia responses in cell lines with normal and deficient DNA repairs systems. Journal of Thermal Biology 30:6, pages 478-484.
Crossref
Frank Pajonk, Arndt van Ophoven & William H. McBride. (2005) Hyperthermia-Induced Proteasome Inhibition and Loss of Androgen Receptor Expression in Human Prostate Cancer Cells. Cancer Research 65:11, pages 4836-4843.
Crossref
Petr Novák, Eduardo G. Moros, William L. Straube & Robert J. Myerson. (2005) SURLAS: A new clinical grade ultrasound system for sequential or concomitant thermoradiotherapy of superficial tumors: Applicator description. Medical Physics 32:1, pages 230-240.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.