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Jekaterīna Ivanova, Morteza Abdoli, Alessio Nocentini, Raivis Žalubovskis & Claudiu T. Supuran. (2023) Derivatives of 4-methyl-1,2,3-benzoxathiazine 2,2-dioxide as selective inhibitors of human carbonic anhydrases IX and XII over the cytosolic isoforms I and II. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Jekaterina Ivanova, Morteza Abdoli, Alessio Nocentini, Raivis Žalubovskis & Claudiu T. Supuran. (2023) 1,2,3-Benzoxathiazine-2,2-dioxides – effective inhibitors of human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1, pages 225-238.
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Amarjyoti Das Mahapatra, Aarfa Queen, Mohd Yousuf, Parvez Khan, Afzal Hussain, Md. Tabish Rehman, Mohamed F. Alajmi, Bhaskar Datta & Md. Imtaiyaz Hassan. (2022) Design and development of 5-(4H)-oxazolones as potential inhibitors of human carbonic anhydrase VA: towards therapeutic management of diabetes and obesity. Journal of Biomolecular Structure and Dynamics 40:7, pages 3144-3154.
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Manuel A. Llanos, María L. Sbaraglini, María L. Villalba, María D. Ruiz, Carolina Carrillo, Catalina Alba Soto, Alan Talevi, Andrea Angeli, Seppo Parkkila, Claudiu T. Supuran & Luciana Gavernet. (2020) A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 21-30.
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Simona Distinto, Rita Meleddu, Francesco Ortuso, Filippo Cottiglia, Serenella Deplano, Lisa Sequeira, Claudia Melis, Benedetta Fois, Andrea Angeli, Clemente Capasso, Rossella Angius, Stefano Alcaro, Claudiu T. Supuran & Elias Maccioni. (2019) Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1526-1533.
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Mohammad M. Al-Sanea, Ahmed Elkamhawy, Sora Paik, Silvia Bua, So Ha Lee, Mohamed A. Abdelgawad, Eun Joo Roh, Wagdy M. Eldehna & Claudiu T. Supuran. (2019) Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1457-1464.
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Andrea Angeli, Sonia Del Prete, Mariana Pinteala, Stelian S. Maier, William A. Donald, Bogdan C. Simionescu, Clemente Capasso & Claudiu T. Supuran. (2019) The first activation study of the β-carbonic anhydrases from the pathogenic bacteria Brucella suis and Francisella tularensis with amines and amino acids. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1178-1185.
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Suleyman Akocak, Nabih Lolak, Silvia Bua, Alessio Nocentini & Claudiu T. Supuran. (2019) Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1193-1198.
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Baijayantimala Swain, Andrea Angeli, Srinivas Angapelly, Pavitra S. Thacker, Priti Singh, Claudiu T. Supuran & Mohammed Arifuddin. (2019) Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1199-1209.
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Pavitra S. Thacker, Pirpasha Shaikh, Andrea Angeli, Mohammed Arifuddin & Claudiu T. Supuran. (2019) Synthesis and biological evaluation of novel 8-substituted quinoline-2-carboxamides as carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1172-1177.
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Alessio Nocentini, Sameh M. Osman, Igor A. Rodrigues, Veronica S. Cardoso, Fatmah Ali S. Alasmary, Zeid AlOthman, Alane B. Vermelho, Paola Gratteri & Claudiu T. Supuran. (2019) Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1164-1171.
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Andreza R. Garcia, Danielle M. P. Oliveira, Ana Claudia F. Amaral, Jéssica B. Jesus, Ana Carolina Rennó Sodero, Alessandra M. T. Souza, Claudiu T. Supuran, Alane B. Vermelho, Igor A. Rodrigues & Anderson S. Pinheiro. (2019) Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1100-1109.
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David Bibi, Bella Shusterman, Alessio Nocentini, Claudiu T. Supuran & Meir Bialer. (2019) Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1078-1082.
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Alessandra Ammazzalorso, Simone Carradori, Andrea Angeli, Atilla Akdemir, Barbara De Filippis, Marialuigia Fantacuzzi, Letizia Giampietro, Cristina Maccallini, Rosa Amoroso & Claudiu T. Supuran. (2019) Fibrate-based N-acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studies. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1051-1061.
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Alessio Nocentini, Daniela Vullo, Sonia Del Prete, Sameh M. Osman, Fatmah A.S. Alasmary, Zeid AlOthman, Clemente Capasso, Fabrizio Carta, Paola Gratteri & Claudiu T. Supuran. (2017) Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1064-1070.
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Claudia Melis, Rita Meleddu, Andrea Angeli, Simona Distinto, Giulia Bianco, Clemente Capasso, Filippo Cottiglia, Rossella Angius, Claudiu T. Supuran & Elias Maccioni. (2017) Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 68-73.
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Adriano Mollica, Marcello Locatelli, Giorgia Macedonio, Simone Carradori, Anatoly P. Sobolev, Roberto F. De Salvador, Simona M. Monti, Martina Buonanno, Gokhan Zengin, Andrea Angeli & Claudiu T. Supuran. (2016) Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup4, pages 1-6.
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Joseph Chukwu, Norman Delanty, David Webb & Gianpiero L Cavalleri. (2014) Weight change, genetics and antiepileptic drugs. Expert Review of Clinical Pharmacology 7:1, pages 43-51.
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Andrea Scozzafava, Claudiu T Supuran & Fabrizio Carta. (2013)
Antiobesity carbonic anhydrase inhibitors: a literature and patent review
. Expert Opinion on Therapeutic Patents 23:6, pages 725-735.
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Asif Husain & Diwakar Madhesia. (2012) Heterocyclic compounds as carbonic anhydrase inhibitor. Journal of Enzyme Inhibition and Medicinal Chemistry 27:6, pages 773-783.
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Claudiu T Supuran. (2012) Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity. Expert Opinion on Emerging Drugs 17:1, pages 11-15.
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Mohammed K. Abdel-Hamid, Atef A. Abdel-Hafez, Nawal A. El-Koussi & Nadia M. Mahfouz. (2009) Quantitative structure–activity relationship (QSAR) studies on a series of 1,3,4-thiadiazole-2-thione derivatives as tumor-associated carbonic anhydrase IX inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 24:3, pages 722-729.
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Isao Nishimori, Tomoko Minakuchi, Saburo Onishi, Daniela Vullo, Alessandro Cecchi, Andrea Scozzafava & Claudiu T. Supuran. (2009) Carbonic anhydrase inhibitors. Cloning, characterization and inhibition studies of the cytosolic isozyme III with anions. Journal of Enzyme Inhibition and Medicinal Chemistry 24:1, pages 70-76.
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Claudiu T Supuran, Anna Di Fiore & Giuseppina De Simone. (2008) Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity. Expert Opinion on Emerging Drugs 13:2, pages 383-392.
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Vivek Khanna, Surendar Arumugam, Subhasis Roy, Shivani Mittra & Vinay S Bansal. (2008) Topiramate and Type 2 diabetes: an old wine in a new bottle. Expert Opinion on Therapeutic Targets 12:1, pages 81-90.
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Ozen OZENSOY, Oktay ARSLAN & Feray KOCKAR. (2008) Differential in vitro inhibition effects of some antibiotics on tumor associated carbonic anhydrase isozymes of hCA-IX and hCA-XII. Journal of Enzyme Inhibition and Medicinal Chemistry 23:4, pages 579-585.
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Gabriela Laura Almajan, Stefania-Felicia Barbuceanu, Alessio innocenti, Andrea Scozzafava & Claudiu T. Supuran. (2008) Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II and IX with some 1,3,4-oxadiazole- and 1,2,4-triazole-thiols. Journal of Enzyme Inhibition and Medicinal Chemistry 23:1, pages 101-107.
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Andrea Scozzafava, Antonio Mastrolorenzo & Claudiu T Supuran. (2006) Carbonic anhydrase inhibitors and activators and their use in therapy. Expert Opinion on Therapeutic Patents 16:12, pages 1627-1664.
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Brian W Clare & Claudiu T Supuran. (2006) A perspective on quantitative structure–activity relationships and carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 2:1, pages 113-137.
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Özen Özensoy, Semra Isik, Oktay Arslan, Mikail Arslan, Andrea Scozzafava & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors. Inhibition of red blood cell ostrich (Struthio camelus) carbonic anhydrase with a series of aromatic and heterocyclic sulfonamides. Journal of Enzyme Inhibition and Medicinal Chemistry 20:4, pages 383-387.
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Jean-Yves Winum, Andrea Scozzafava, Jean-Louis Montero & Claudiu T Supuran. (2004) Therapeutic applications of sulfamates. Expert Opinion on Therapeutic Patents 14:9, pages 1273-1308.
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Andrea Scozzafava, Antonio Mastrolorenzo & Claudiu T Supuran. (2004) Modulation of carbonic anhydrase activity and its applications in therapy. Expert Opinion on Therapeutic Patents 14:5, pages 667-702.
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Laura Micheli, Lara Testai, Andrea Angeli, Donatello Carrino, Alessandra Pacini, Francesco Margiotta, Lorenzo Flori, Claudiu T. Supuran, Vincenzo Calderone, Carla Ghelardini & Lorenzo Di Cesare Mannelli. (2022) Inhibitors of Mitochondrial Human Carbonic Anhydrases VA and VB as a Therapeutic Strategy against Paclitaxel-Induced Neuropathic Pain in Mice. International Journal of Molecular Sciences 23:11, pages 6229.
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Farhan M. Khan, Muhammad A. Abbasi, Aziz‐ur‐Rehman, Sabahat Z. Siddiqui, Abdul R. Sadiq Butt, Hussain Raza, Ayesha Zafar, Syed A. Ali Shah, Muhammad Shahid & Sung‐Yum Seo. (2021) Convergent synthesis of carbonic anhydrase inhibiting bi‐heterocyclic benzamides: Structure–activity relationship and mechanistic explorations through enzyme inhibition, kinetics, and computational studies. Journal of Heterocyclic Chemistry 58:5, pages 1089-1103.
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Mostafa M. Ghorab, Aiten M. Soliman, Silvia Bua & Claudiu T. Supuran. (2021) Biological evaluation, radiosensitizing activity and structural insights of novel halogenated quinazoline-sulfonamide conjugates as selective human carbonic anhydrases IX/XII inhibitors. Bioorganic Chemistry 107, pages 104618.
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Aiga Grandāne, Alessio Nocentini, Ilona Domračeva, Raivis Žalubovskis & Claudiu T. Supuran. (2020) Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII. European Journal of Medicinal Chemistry 200, pages 112300.
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Zan Li, Li Jiang & Shinya Toyokuni. (2020) Role of carbonic anhydrases in ferroptosis-resistance. Archives of Biochemistry and Biophysics 689, pages 108440.
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Aiga Grandane, Alessio Nocentini, Thomas Werner, Raivis Zalubovskis & Claudiu T. Supuran. (2020) Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors. Bioorganic & Medicinal Chemistry 28:11, pages 115496.
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Ayşegül Sümer, Eşref Edip Keha, Ahmet Menteşe & Ahmet Alver. (2020) Effects of topiramate on adipocyte differentiation and gene expression of certain carbonic anhydrase isoenzymes. Turkish Journal of Biochemistry 45:2, pages 121-129.
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Seyed-Omar Zaraei, Mohammed I. El-Gamal, Zainab Shafique, Sayyeda Tayyeba Amjad, Saifullah Afridi, Sumera Zaib, Hanan S. Anbar, Randa El-Gamal & Jamshed Iqbal. (2019) Sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as potent carbonic anhydrase II/IX/XII inhibitors. Bioorganic & Medicinal Chemistry 27:17, pages 3889-3901.
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Emanuela Berrino & Fabrizio Carta. 2019. Carbonic Anhydrases. Carbonic Anhydrases
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Alessio Nocentini, William A. Donald & Claudiu T. Supuran. 2019. Carbonic Anhydrases. Carbonic Anhydrases
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Claudiu Supuran. (2018) Carbonic Anhydrases and Metabolism. Metabolites 8:2, pages 25.
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Parham Taslimi, Afsun Sujayev, Fikret Turkan, Emin Garibov, Zübeyir Huyut, Vagif Farzaliyev, Sevgi Mamedova & İlhami Gulçin. (2018) Synthesis and investigation of the conversion reactions of pyrimidine-thiones with nucleophilic reagent and evaluation of their acetylcholinesterase, carbonic anhydrase inhibition, and antioxidant activities. Journal of Biochemical and Molecular Toxicology 32:2, pages e22019.
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Claudiu T. Supuran. (2017) Bortezomib inhibits mammalian carbonic anhydrases. Bioorganic & Medicinal Chemistry 25:19, pages 5064-5067.
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Panagiotis K. Chrysanthopoulos, Prashant Mujumdar, Lucy A. Woods, Olan Dolezal, Bin Ren, Thomas S. Peat & Sally-Ann Poulsen. (2017) Identification of a New Zinc Binding Chemotype by Fragment Screening. Journal of Medicinal Chemistry 60:17, pages 7333-7349.
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Riccardo Nescatelli, Simone Carradori, Federico Marini, Vicky Caponigro, Remo Bucci, Celeste De Monte, Adriano Mollica, Luisa Mannina, Mariangela Ceruso, Claudiu T. Supuran & Daniela Secci. (2017) Geographical characterization by MAE-HPLC and NIR methodologies and carbonic anhydrase inhibition of Saffron components. Food Chemistry 221, pages 855-863.
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Daniela Vullo, Sonia Del Prete, Alessio Nocentini, Sameh M. Osman, Zeid AlOthman, Clemente Capasso, Murat Bozdag, Fabrizio Carta, Paola Gratteri & Claudiu T. Supuran. (2017) Dithiocarbamates effectively inhibit the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa. Bioorganic & Medicinal Chemistry 25:3, pages 1260-1265.
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Murat Bozdag, Ahmed Mahmoud Alafeefy, Abdul Malik Altamimi, Daniela Vullo, Fabrizio Carta & Claudiu T. Supuran. (2017) Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity. Bioorganic & Medicinal Chemistry 25:2, pages 677-683.
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Murtuza Hadianawala & Bhaskar Datta. (2016) Design and development of sulfonylurea derivatives as zinc metalloenzyme modulators. RSC Advances 6:11, pages 8923-8929.
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Adel S. El-Azab, Alaa A.-M. Abdel-Aziz, Rezk R. Ayyad, Mariangela Ceruso & Claudiu T. Supuran. (2016) Inhibition of carbonic anhydrase isoforms I, II, IV, VII and XII with carboxylates and sulfonamides incorporating phthalimide/phthalic anhydride scaffolds. Bioorganic & Medicinal Chemistry 24:1, pages 20-25.
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Murat Bozdag, Ahmed M. Alafeefy, Daniela Vullo, Fabrizio Carta, Nurcan Dedeoglu, Abdul-Malek S. Al-Tamimi, Nabila A. Al-Jaber, Andrea Scozzafava & Claudiu T. Supuran. (2015) Benzenesulfonamides incorporating bulky aromatic/heterocyclic tails with potent carbonic anhydrase inhibitory activity. Bioorganic & Medicinal Chemistry 23:24, pages 7751-7764.
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Alfonso Maresca, Gulay Akyuz, Sameh M. Osman, Zeid AlOthman & Claudiu T. Supuran. (2015) Inhibition of mammalian carbonic anhydrase isoforms I–XIV with a series of phenolic acid esters. Bioorganic & Medicinal Chemistry 23:22, pages 7181-7188.
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Alessio Nocentini, Fabrizio Carta, Mariangela Ceruso, Gianluca Bartolucci & Claudiu T. Supuran. (2015) Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII. Bioorganic & Medicinal Chemistry 23:21, pages 6955-6966.
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İbrahim Esirden, Ramazan Ulus, Burak Aday, Muhammet Tanç, Claudiu T. Supuran & Muharrem Kaya. (2015) Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII. Bioorganic & Medicinal Chemistry 23:20, pages 6573-6580.
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Atilla Akdemir & Özlen Güzel-Akdemir. 2015. Carbonic Anhydrases as Biocatalysts. Carbonic Anhydrases as Biocatalysts
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138
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Mariangela Ceruso, Sabrina Antel, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2014) Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I–XIV. Bioorganic & Medicinal Chemistry 22:24, pages 6768-6775.
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Fabrizio Carta, Claudiu T Supuran & Andrea Scozzafava. (2014) Sulfonamides and their isosters as carbonic anhydrase inhibitors. Future Medicinal Chemistry 6:10, pages 1149-1165.
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Aiga Grandane, Muhammet Tanc, Raivis Zalubovskis & Claudiu T. Supuran. (2014) 6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII. Bioorganic & Medicinal Chemistry Letters 24:5, pages 1256-1260.
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Aiga Grandane, Muhammet Tanc, Raivis Zalubovskis & Claudiu T. Supuran. (2014) Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII. Bioorganic & Medicinal Chemistry 22:5, pages 1522-1528.
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Giuseppina De Simone, Ginta Pizika, Simona Maria Monti, Anna Di Fiore, Jekaterina Ivanova, Igor Vozny, Peteris Trapencieris, Raivis Zalubovskis, Claudiu T. Supuran & Vincenzo Alterio. (2014) Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors. BioMed Research International 2014, pages 1-11.
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Sally-Ann Poulsen & Rohan A. Davis. 2014. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications
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Meenakshi N. Deodhar, Priyanka L. Khopade & Mahesh G. Varat. (2013)
Sulfonamide Based
β
-Carbonic Anhydrase Inhibitors: 2D QSAR Study
. ISRN Medicinal Chemistry 2013, pages 1-8.
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Mariangela Ceruso, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2013) Inhibition of human carbonic anhydrase isoforms I–XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties. Bioorganic & Medicinal Chemistry 21:22, pages 6929-6936.
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Shyamasri Biswas, Robert McKenna & Claudiu T. Supuran. (2013) Effect of incorporating a thiophene tail in the scaffold of acetazolamide on the inhibition of human carbonic anhydrase isoforms I, II, IX and XII. Bioorganic & Medicinal Chemistry Letters 23:20, pages 5646-5649.
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Ramazan Ulus, İbrahim Yeşildağ, Muhammet Tanç, Metin Bülbül, Muharrem Kaya & Claudiu T. Supuran. (2013) Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII. Bioorganic & Medicinal Chemistry 21:18, pages 5799-5805.
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Janis Leitans, Agnese Sprudza, Muhammet Tanc, Igor Vozny, Raivis Zalubovskis, Kaspars Tars & Claudiu T. Supuran. (2013) 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: Solution and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry 21:17, pages 5130-5138.
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Muhammet Tanc, Fabrizio Carta, Murat Bozdag, Andrea Scozzafava & Claudiu T. Supuran. (2013) 7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors. Bioorganic & Medicinal Chemistry 21:15, pages 4502-4510.
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Shalini Singh & Claudiu T. Supuran. (2013) Chemometric QSAR modeling and in silico design of carbonic anhydrase inhibition of a coral secretory isoform by sulfonamide. Bioorganic & Medicinal Chemistry 21:6, pages 1495-1502.
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Guillaume Compain, Agnès Martin-Mingot, Alfonso Maresca, Sebastien Thibaudeau & Claudiu T. Supuran. (2013) Superacid synthesis of halogen containing N-substituted-4-aminobenzene sulfonamides: New selective tumor-associated carbonic anhydrase inhibitors. Bioorganic & Medicinal Chemistry 21:6, pages 1555-1563.
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N. N. Romanova, I. I. Rybalko, T. G. Tallo, N. V. Zyk & V. K. Švedas. (2012) Synthesis of Schiff bases from 3-amino-3-arylpropionic acid esters in aqueous medium. Russian Journal of Organic Chemistry 48:6, pages 860-863.
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Isao Nishimori, Tomoko Minakuchi, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2011) Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. Bioorganic & Medicinal Chemistry 19:16, pages 5023-5030.
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Alfonso Maresca & Claudiu T. Supuran. (2011) (R)-/(S)-10-Camphorsulfonyl-substituted aromatic/heterocyclic sulfonamides selectively inhibit mitochondrial over cytosolic carbonic anhydrases. Bioorganic & Medicinal Chemistry Letters 21:5, pages 1334-1337.
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Gyles E. Cozier, Mathew P. Leese, Matthew D. Lloyd, Matthew D. Baker, Nethaji Thiyagarajan, K. Ravi Acharya & Barry V. L. Potter. (2010)
Structures of Human Carbonic Anhydrase II/Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Nonsteroidal Inhibitors
,
. Biochemistry 49:16, pages 3464-3476.
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Daniela Vullo, Isao Nishimori, Andrea Scozzafava, Stephan Köhler, Jean-Yves Winum & Claudiu T. Supuran. (2010) Inhibition studies of a β-carbonic anhydrase from Brucella suis with a series of water soluble glycosyl sulfanilamides. Bioorganic & Medicinal Chemistry Letters 20:7, pages 2178-2182.
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Pascale Joseph, François Turtaut, Safia Ouahrani-Bettache, Jean-Louis Montero, Isao Nishimori, Tomoko Minakuchi, Daniela Vullo, Andrea Scozzafava, Stephan Köhler, Jean-Yves Winum & Claudiu T. Supuran. (2010)
Cloning, Characterization, and Inhibition Studies of a β-Carbonic Anhydrase from
Brucella suis
. Journal of Medicinal Chemistry 53:5, pages 2277-2285.
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Alessio Innocenti, S. Beyza Öztürk Sarıkaya, İlhami Gülçin & Claudiu T. Supuran. (2010) Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I–XIV with a series of natural product polyphenols and phenolic acids. Bioorganic & Medicinal Chemistry 18:6, pages 2159-2164.
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Rohan A. Davis, Alessio Innocenti, Sally-Ann Poulsen & Claudiu T. Supuran. (2010) Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library. Bioorganic & Medicinal Chemistry 18:1, pages 14-18.
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Brij Sharma, Pradeep Pilania, Prithvi Singh, Susheela Sharma & Yenamandra Prabhakar. (2009) CP-MLR directed QSAR study of carbonic anhydrase inhibitors: sulfonamide and sulfamate inhibitors. Open Chemistry 7:4, pages 909-922.
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Rosa Maria Vitale, Vincenzo Alterio, Alessio Innocenti, Jean-Yves Winum, Simona Maria Monti, Giuseppina De Simone & Claudiu T. Supuran. (2009) Carbonic Anhydrase Inhibitors. Comparison of Aliphatic Sulfamate/Bis-sulfamate Adducts with Isozymes II and IX as a Platform for Designing Tight-Binding, More Isoform-Selective Inhibitors. Journal of Medicinal Chemistry 52:19, pages 5990-5998.
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Jean-Yves Winum, Alessio Innocenti, Daniela Vullo, Jean-Louis Montero & Claudiu T. Supuran. (2009) Carbonic anhydrase inhibitors; Fluorinated phenyl sulfamates show strong inhibitory activity and selectivity for the inhibition of the tumor-associated isozymes IX and XII over the cytosolic ones I and II. Bioorganic & Medicinal Chemistry Letters 19:17, pages 5082-5085.
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Giuseppina De Simone & Claudiu T. Supuran. 2009. Drug Design of Zinc‐Enzyme Inhibitors. Drug Design of Zinc‐Enzyme Inhibitors
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254
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Özlen Güzel, Alessio Innocenti, Andrea Scozzafava, Aydın Salman & Claudiu T. Supuran. (2009) Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB. Bioorganic & Medicinal Chemistry 17:14, pages 4894-4899.
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Alessio Innocenti, Rebecca A. Hall, Christine Schlicker, Andrea Scozzafava, Clemens Steegborn, Fritz A. Mühlschlegel & Claudiu T. Supuran. (2009) Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal β-carbonic anhydrase from Candida albicans with sulfonamides. Bioorganic & Medicinal Chemistry 17:13, pages 4503-4509.
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Jean-Yves Winum, Alessio Innocenti, Andrea Scozzafava, Jean-Louis Montero & Claudiu T. Supuran. (2009) Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isoforms I and II and transmembrane, tumor-associated isoforms IX and XII with boronic acids. Bioorganic & Medicinal Chemistry 17:10, pages 3649-3652.
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Claudia Temperini, Alessandro Cecchi, Andrea Scozzafava & Claudiu T. Supuran. (2009) Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference. Bioorganic & Medicinal Chemistry 17:3, pages 1214-1221.
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Claudia Temperini, Alessandro Cecchi, Andrea Scozzafava & Claudiu T. Supuran. (2008) Carbonic Anhydrase Inhibitors. Comparison of Chlorthalidone and Indapamide X-ray Crystal Structures in Adducts with Isozyme II: When Three Water Molecules and the Keto−Enol Tautomerism Make the Difference. Journal of Medicinal Chemistry 52:2, pages 322-328.
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Fatma-Zohra Smaine, Fabio Pacchiano, Marouan Rami, Véronique Barragan-Montero, Daniela Vullo, Andrea Scozzafava, Jean-Yves Winum & Claudiu T. Supuran. (2008) Carbonic anhydrase inhibitors: 2-Substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV. Bioorganic & Medicinal Chemistry Letters 18:24, pages 6332-6335.
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Sally-Ann Poulsen, Brendan L. Wilkinson, Alessio Innocenti, Daniela Vullo & Claudiu T. Supuran. (2008) Inhibition of human mitochondrial carbonic anhydrases VA and VB with para-(4-phenyltriazole-1-yl)-benzenesulfonamide derivatives. Bioorganic & Medicinal Chemistry Letters 18:16, pages 4624-4627.
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Daniela Vullo, Isao Nishimori, Andrea Scozzafava & Claudiu T. Supuran. (2008) Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines. Bioorganic & Medicinal Chemistry Letters 18:15, pages 4303-4307.
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Anna Di Fiore, Carlo Pedone, Jochen Antel, Harald Waldeck, Andreas Witte, Michael Wurl, Andrea Scozzafava, Claudiu T. Supuran & Giuseppina De Simone. (2008) Carbonic anhydrase inhibitors: The X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors. Bioorganic & Medicinal Chemistry Letters 18:8, pages 2669-2674.
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Katia D'Ambrosio, Bernard Masereel, Anne Thiry, Andrea Scozzafava, Claudiu T. Supuran & Giuseppina De Simone. (2008) Carbonic Anhydrase Inhibitors: Binding of Indanesulfonamides to the Human Isoform II. ChemMedChem 3:3, pages 473-477.
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Brendan L. Wilkinson, Alessio Innocenti, Daniela Vullo, Claudiu T. Supuran & Sally-Ann Poulsen. (2008) Inhibition of Carbonic Anhydrases with Glycosyltriazole Benzene Sulfonamides. Journal of Medicinal Chemistry 51:6, pages 1945-1953.
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Vijay M. Krishnamurthy, George K. Kaufman, Adam R. Urbach, Irina Gitlin, Katherine L. Gudiksen, Douglas B. Weibel & George M. Whitesides. (2008) Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding. Chemical Reviews 108:3, pages 946-1051.
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Claudiu T. Supuran. (2008) Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nature Reviews Drug Discovery 7:2, pages 168-181.
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Claudia Temperini, Alessandro Cecchi, Nicholas A. Boyle, Andrea Scozzafava, Jaime Escribano Cabeza, Paul WentworthJr.Jr., G. Michael Blackburn & Claudiu T. Supuran. (2008) Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: Kinetic and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry Letters 18:3, pages 999-1005.
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Özlen Güzel, Claudia Temperini, Alessio Innocenti, Andrea Scozzafava, Aydın Salman & Claudiu T. Supuran. (2008) Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: Kinetic and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry Letters 18:1, pages 152-158.
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Isao Nishimori, Tomoko Minakuchi, Saburo Onishi, Daniela Vullo, Alessandro Cecchi, Andrea Scozzafava & Claudiu T. Supuran. (2007) Carbonic anhydrase inhibitors: Cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides. Bioorganic & Medicinal Chemistry 15:23, pages 7229-7236.
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Tiziano Tuccinardi, Gabriella Ortore, Armando Rossello, Claudiu T. Supuran & Adriano Martinelli. (2007) Homology Modeling and Receptor-Based 3D-QSAR Study of Carbonic Anhydrase IX. Journal of Chemical Information and Modeling 47:6, pages 2253-2262.
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Isao Nishimori, Alessio Innocenti, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2007) Carbonic anhydrase inhibitors: The inhibition profiles of the human mitochondrial isoforms VA and VB with anions are very different. Bioorganic & Medicinal Chemistry 15:21, pages 6742-6747.
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Mohammed K. Abdel-Hamid, Atef A. Abdel-Hafez, Nawal A. El-Koussi, Nadia M. Mahfouz, Alessio Innocenti & Claudiu T. Supuran. (2007) Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity. Bioorganic & Medicinal Chemistry 15:22, pages 6975-6984.
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Vincenzo Alterio, Giuseppina De Simone, Simona Maria Monti, Andrea Scozzafava & Claudiu T. Supuran. (2007) Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides—Solution and crystallographic studies. Bioorganic & Medicinal Chemistry Letters 17:15, pages 4201-4207.
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Isao Nishimori, Tomoko Minakuchi, Takuhiro Kohsaki, Saburo Onishi, Hiroaki Takeuchi, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2007) Carbonic anhydrase inhibitors: The β-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors. Bioorganic & Medicinal Chemistry Letters 17:13, pages 3585-3594.
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Rosa Maria Vitale, Carlo Pedone, Pietro Amodeo, Jochen Antel, Michael Wurl, Andrea Scozzafava, Claudiu T. Supuran & Giuseppina De Simone. (2007) Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA. Bioorganic & Medicinal Chemistry 15:12, pages 4152-4158.
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Claudiu T Supuran. (2007) Therapeutic applications of the carbonic anhydrase inhibitors. Therapy 4:3, pages 355-378.
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Jean-Yves Winum, Anne Thiry, Khaled El Cheikh, Jean-Michel Dogné, Jean-Louis Montero, Daniela Vullo, Andrea Scozzafava, Bernard Masereel & Claudiu T. Supuran. (2007) Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose–thioureido tails. Bioorganic & Medicinal Chemistry Letters 17:10, pages 2685-2691.
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Brendan L. Wilkinson, Laurent F. Bornaghi, Todd A. Houston, Alessio Innocenti, Daniela Vullo, Claudiu T. Supuran & Sally-Ann Poulsen. (2007)
Carbonic Anhydrase Inhibitors: Inhibition of Isozymes I, II, and IX with Triazole-Linked
O
-Glycosides of Benzene Sulfonamides
. Journal of Medicinal Chemistry 50:7, pages 1651-1657.
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Claudia Temperini, Alessio Innocenti, Annalisa Guerri, Andrea Scozzafava, Stefano Rusconi & Claudiu T. Supuran. (2007) Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I. Bioorganic & Medicinal Chemistry Letters 17:8, pages 2210-2215.
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Steven P. Vickers & Sharon C. Cheetham. 2007. Appetite and Body Weight. Appetite and Body Weight
323
336
.
Jean-Yves Winum, Claudia Temperini, Khaled El Cheikh, Alessio Innocenti, Daniela Vullo, Samuele Ciattini, Jean-Louis Montero, Andrea Scozzafava & Claudiu T. Supuran. (2006) Carbonic Anhydrase Inhibitors: Clash with Ala65 as a Means for Designing Inhibitors with Low Affinity for the Ubiquitous Isozyme II, Exemplified by the Crystal Structure of the Topiramate Sulfamide Analogue. Journal of Medicinal Chemistry 49:24, pages 7024-7031.
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Anne Thiry, Jean-Michel Dogné, Bernard Masereel & Claudiu T. Supuran. (2006) Targeting tumor-associated carbonic anhydrase IX in cancer therapy. Trends in Pharmacological Sciences 27:11, pages 566-573.
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Jean-Yves Winum, Andrea Scozzafava, Jean-Louis Montero & Claudiu T. Supuran. (2006) Therapeutic potential of sulfamides as enzyme inhibitors. Medicinal Research Reviews 26:6, pages 767-792.
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Claudia Temperini, Andrea Scozzafava, Daniela Vullo & Claudiu T. Supuran. (2006)
Carbonic Anhydrase Activators. Activation of Isozymes I, II, IV, VA, VII, and XIV with
L
‐ and
D
‐Histidine and Crystallographic Analysis of Their Adducts with Isoform II: Engineering Proton‐Transfer Processes within the Active Site of an Enzyme
. Chemistry – A European Journal 12:27, pages 7057-7066.
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Vincenzo Alterio, Rosa Maria Vitale, Simona Maria Monti, Carlo Pedone, Andrea Scozzafava, Alessandro Cecchi, Giuseppina De Simone & Claudiu T. Supuran. (2006) Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX. Journal of the American Chemical Society 128:25, pages 8329-8335.
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Claudia Temperini, Andrea Scozzafava, Daniela Vullo & Claudiu T. Supuran. (2006)
Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, VA, VII, and XIV with
l
- and
d
-Phenylalanine and Crystallographic Analysis of Their Adducts with Isozyme II: Stereospecific Recognition within the Active Site of an Enzyme and Its Consequences for the Drug Design
. Journal of Medicinal Chemistry 49:10, pages 3019-3027.
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Isao Nishimori, Daniela Vullo, Tomoko Minakuchi, Kaori Morimoto, Saburo Onishi, Andrea Scozzafava & Claudiu T. Supuran. (2006) Carbonic anhydrase inhibitors: Cloning and sulfonamide inhibition studies of a carboxyterminal truncated α-carbonic anhydrase from Helicobacter pylori. Bioorganic & Medicinal Chemistry Letters 16:8, pages 2182-2188.
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Isao Nishimori, Tomoko Minakuchi, Kaori Morimoto, Shuichi Sano, Saburo Onishi, Hiroaki Takeuchi, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2006)
Carbonic Anhydrase Inhibitors: DNA Cloning and Inhibition Studies of the α-Carbonic Anhydrase from
Helicobacter pylori
, A New Target for Developing Sulfonamide and Sulfamate Gastric Drugs
. Journal of Medicinal Chemistry 49:6, pages 2117-2126.
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Isao Nishimori, Daniela Vullo, Alessio Innocenti, Andrea Scozzafava, Antonio Mastrolorenzo & Claudiu T. Supuran. (2005) Carbonic Anhydrase Inhibitors. The Mitochondrial Isozyme VB as a New Target for Sulfonamide and Sulfamate Inhibitors. Journal of Medicinal Chemistry 48:24, pages 7860-7866.
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Alessandro Cecchi, Scott D. Taylor, Yong Liu, Bryan Hill, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors: Inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides. Bioorganic & Medicinal Chemistry Letters 15:23, pages 5192-5196.
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Özen Özensoy, Luca Puccetti, Giuseppe Fasolis, Oktay Arslan, Andrea Scozzafava & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors: Inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides. Bioorganic & Medicinal Chemistry Letters 15:21, pages 4862-4866.
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Valeria Menchise, Giuseppina De Simone, Vincenzo Alterio, Anna Di Fiore, Carlo Pedone, Andrea Scozzafava & Claudiu T. Supuran. (2005) Carbonic Anhydrase Inhibitors: Stacking with Phe131 Determines Active Site Binding Region of Inhibitors As Exemplified by the X-ray Crystal Structure of a Membrane-Impermeant Antitumor Sulfonamide Complexed with Isozyme II. Journal of Medicinal Chemistry 48:18, pages 5721-5727.
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Luca Puccetti, Giuseppe Fasolis, Daniela Vullo, Zahid H. Chohan, Andrea Scozzafava & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff’s bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes. Bioorganic & Medicinal Chemistry Letters 15:12, pages 3096-3101.
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Giuseppina De Simone, Anna Di Fiore, Valeria Menchise, Carlo Pedone, Jochen Antel, Angela Casini, Andrea Scozzafava, Michael Wurl & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry Letters 15:9, pages 2315-2320.
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Gabriela Laura Almajan, Alessio Innocenti, Luca Puccetti, Gheorghe Manole, Stefania Barbuceanu, Ioana Saramet, Andrea Scozzafava & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols. Bioorganic & Medicinal Chemistry Letters 15:9, pages 2347-2352.
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Anna Di Fiore, Giuseppina De Simone, Valeria Menchise, Carlo Pedone, Angela Casini, Andrea Scozzafava & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II. Bioorganic & Medicinal Chemistry Letters 15:7, pages 1937-1942.
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Alessio Innocenti, Jochen Antel, Michael Wurl, Daniela Vullo, Michael A. Firnges, Andrea Scozzafava & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V and IX with complex fluorides, chlorides and cyanides. Bioorganic & Medicinal Chemistry Letters 15:7, pages 1909-1913.
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Jean-Yves Winum, Alessio Innocenti, Valerie Gagnard, Jean-Louis Montero, Andrea Scozzafava, Daniela Vullo & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with organic phosphates and phosphonates. Bioorganic & Medicinal Chemistry Letters 15:6, pages 1683-1686.
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Jean‐Yves Winum, Andrea Scozzafava, Jean‐Louis Montero & Claudiu T. Supuran. (2004) Sulfamates and their therapeutic potential. Medicinal Research Reviews 25:2, pages 186-228.
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Matthew D. LLOYDRichard L. PEDERICKRamanathan NATESHL. W. Lawrence WOOAtul PUROHITMichael J. REEDK. Ravi ACHARYABarry V. L. POTTER. (2005) Crystal structure of human carbonic anhydrase II at 1.95 Å resolution in complex with 667-coumate, a novel anti-cancer agent. Biochemical Journal 385:3, pages 715-720.
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Daniela Vullo, Juha Voipio, Alessio Innocenti, Claudio Rivera, Harri Ranki, Andrea Scozzafava, Kai Kaila & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. Bioorganic & Medicinal Chemistry Letters 15:4, pages 971-976.
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Alessio Innocenti, Daniela Vullo, Andrea Scozzafava, Joseph R. Casey & ClaudiuT. Supuran. (2005) Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates. Bioorganic & Medicinal Chemistry Letters 15:3, pages 573-578.
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Alessio Innocenti, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate. Bioorganic & Medicinal Chemistry Letters 15:3, pages 567-571.
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Jerapan Krungkrai, Andrea Scozzafava, Sutarnthip Reungprapavut, Sudaratana R. Krungkrai, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan & Claudiu T. Supuran. (2005) Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action?. Bioorganic & Medicinal Chemistry 13:2, pages 483-489.
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Stefano Rusconi, Alessio Innocenti, Daniela Vullo, Antonio Mastrolorenzo, Andrea Scozzafava & Claudiu T. Supuran. (2004) Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet. Bioorganic & Medicinal Chemistry Letters 14:23, pages 5763-5767.
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Alessio Innocenti, Michael A. Firnges, Jochen Antel, Michael Wurl, Andrea Scozzafava & Claudiu T. Supuran. (2004) Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions. Bioorganic & Medicinal Chemistry Letters 14:23, pages 5769-5773.
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Alessio Innocenti, Jonna M. Lehtonen, Seppo Parkkila, Andrea Scozzafava & Claudiu T. Supuran. (2004) Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions. Bioorganic & Medicinal Chemistry Letters 14:21, pages 5435-5439.
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Alessio Innocenti, Jochen Antel, Michael Wurl, Andrea Scozzafava & Claudiu T. Supuran. (2004) Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives. Bioorganic & Medicinal Chemistry Letters 14:22, pages 5703-5707.
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Daniela Vullo, Andrea Scozzafava, Silvia Pastorekova, Jaromir Pastorek & Claudiu T Supuran. (2004) Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered. Bioorganic & Medicinal Chemistry Letters 14:9, pages 2351-2356.
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Daniela Vullo, Marco Franchi, Enzo Gallori, Jochen Antel, Andrea Scozzafava & Claudiu T. Supuran. (2004) Carbonic Anhydrase Inhibitors. Inhibition of Mitochondrial Isozyme V with Aromatic and Heterocyclic Sulfonamides. Journal of Medicinal Chemistry 47:5, pages 1272-1279.
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Francesco Abbate, Anita Coetzee, Angela Casini, Samuele Ciattini, Andrea Scozzafava & Claudiu T. Supuran. (2004) Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride. Bioorganic & Medicinal Chemistry Letters 14:2, pages 337-341.
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