Autophagy, Volume 17, Issue 4 (2021)

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Autophagy, Volume 17, Issue 4 (2021)

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Editor’s Corner

Article Commentary
Did evolution choose Atg11 as the scaffolding platform beyond selective autophagy?
Yuxiang J. Huang & Daniel J. Klionsky
Pages: 835-836
Published online: 14 Jan 2021
AbstractforDid evolution choose Atg11 as the scaffolding platform beyond selective autophagy? | Full Text | References | PDF (213.2 KB) | EPUB
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Artophagosome

Article
Autophagy as an on-ramp to scientific discovery
Casey Garr, Candyce M. Sturgeon, Noah Franks & Veronica A. Segarra
Pages: 837-839
Published online: 16 Jun 2020
AbstractforAutophagy as an on-ramp to scientific discovery | Full Text | References | PDF (2.8 MB) | EPUB
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Research Paper

Article
Oncogenic role of MIR516A in human bladder cancer was mediated by its attenuating PHLPP2 expression and BECN1-dependent autophagy
Honglei Jin, Jiugao Ma, Jiheng Xu, Hongyan Li, Yuanyuan Chang, Nan Zang, Zhongxian Tian, Xin Wang, Nannan Zhao, Lu Liu, Caiyi Chen, Qipeng Xie, Yongyong Lu, Zhouxi Fang, Xing Huang, Chuanshu Huang & Haishan Huang
Pages: 840-854
Published online: 01 Mar 2020
AbstractforOncogenic role of MIR516A in human bladder cancer was mediated by its attenuating PHLPP2 expression and BECN1-dependent autophagy | Full Text | References | PDF (4.1 MB) | EPUB | Supplemental
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Open Access

Toolbox

Article
A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons
Petros Stathakos, Natalia Jiménez-Moreno, Lucy A. Crompton, Paul A. Nistor, Jennifer L. Badger, Peter A Barbuti, Talitha L. Kerrigan, Andrew D. Randall, Maeve A. Caldwell & Jon D. Lane
Pages: 855-871
Published online: 14 Apr 2020
AbstractforA monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons | Full Text | References | PDF (15.4 MB) | EPUB | Supplemental
  • 9245 Views
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Open Access

Research Paper

Article
Sulforaphane Activates a lysosome-dependent transcriptional program to mitigate oxidative stress
Dan Li, Rong Shao, Na Wang, Nan Zhou, Kaili Du, Jiahui Shi, Yihan Wang, Zhuangzhuang Zhao, Xin Ye, Xiaoli Zhang & Haoxing Xu
Pages: 872-887
Published online: 15 Mar 2020
AbstractforSulforaphane Activates a lysosome-dependent transcriptional program to mitigate oxidative stress | Full Text | References | PDF (5.6 MB) | EPUB | Supplemental
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Article
The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils
Tomasz K. Prajsnar, Justyna J. Serba, Bernice M. Dekker, Josie F. Gibson, Samrah Masud, Angeleen Fleming, Simon A. Johnston, Stephen A. Renshaw & Annemarie H. Meijer
Pages: 888-902
Published online: 15 Mar 2020
AbstractforThe autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils | Full Text | References | PDF (6.1 MB) | EPUB | Supplemental
  • 7380 Views
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Open Access
Article
KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity
Mengyu Liu, Huifeng Pi, Yu Xi, Liting Wang, Li Tian, Mengyan Chen, Jia Xie, Ping Deng, Tao Zhang, Chao Zhou, Yidan Liang, Lei Zhang, Mindi He, Yonghui Lu, Chunhai Chen, Zhengping Yu & Zhou Zhou
Pages: 903-924
Published online: 30 Mar 2020
AbstractforKIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity | Full Text | References | PDF (5.7 MB) | EPUB | Supplemental
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Article
Induction of autophagy and suppression of type I IFN secretion by CSFV
Baoming Xie, Mingqiu Zhao, Dan Song, Keke Wu, Lin Yi, Wenhui Li, Xiaoming Li, Kun Wang & Jinding Chen
Pages: 925-947
Published online: 21 Mar 2020
AbstractforInduction of autophagy and suppression of type I IFN secretion by CSFV | Full Text | References | PDF (6.2 MB) | EPUB
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Article
Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death
Changfeng Li, Ying Zhang, Jiao Liu, Rui Kang, Daniel J. Klionsky & Daolin Tang
Pages: 948-960
Published online: 18 Mar 2020
AbstractforMitochondrial DNA stress triggers autophagy-dependent ferroptotic death | Full Text | References | PDF (3.3 MB) | EPUB
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Article
Crosstalk between HSPA5 arginylation and sequential ubiquitination leads to AKT degradation through autophagy flux
Hyo Jeong Kim, Sun-Yong Kim, Dae-Ho Kim, Joon Seong Park, Seong Hyun Jeong, Young Won Choi & Chul-Ho Kim
Pages: 961-979
Published online: 21 Mar 2020
AbstractforCrosstalk between HSPA5 arginylation and sequential ubiquitination leads to AKT degradation through autophagy flux | Full Text | References | PDF (7.6 MB) | EPUB | Supplemental
  • 4413 Views
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Article
The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis
Shulan Pi, Ling Mao, Jiefang Chen, Hanqing Shi, Yuxiao Liu, Xiaoqing Guo, Yuanyuan Li, Lian Zhou, Hui He, Cheng Yu, Jianyong Liu, Yiping Dang, Yuanpeng Xia, Quanwei He, Huijuan Jin, Yanan Li, Yu Hu, Yiliang Miao, Zhenyu Yue & Bo Hu
Pages: 980-1000
Published online: 19 Mar 2020
AbstractforThe P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis | Full Text | References | PDF (10.8 MB) | EPUB | Supplemental
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Brief Report

Brief Report
Nucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma
Firli Rahmah Primula Dewi, Shabierjiang Jiapaer, Akiko Kobayashi, Masaharu Hazawa, Dini Kurnia Ikliptikawati, Hartono, Hemragul Sabit, Mitsutoshi Nakada & Richard W. Wong
Pages: 1001-1012
Published online: 24 Mar 2020
AbstractforNucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma | Full Text | References | PDF (4.6 MB) | EPUB | Supplemental
  • 4975 Views
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Open Access

Research Paper

Article
The trehalose-6-phosphate phosphatase Tps2 regulates ATG8 transcription and autophagy in Saccharomyces cerevisiae
Bongkeun Kim, Yongook Lee, Hyojeong Choi & Won-Ki Huh
Pages: 1013-1027
Published online: 02 Apr 2020
AbstractforThe trehalose-6-phosphate phosphatase Tps2 regulates ATG8 transcription and autophagy in Saccharomyces cerevisiae | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
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Meeting Report

Puncta intended: connecting the dots between autophagy and cell stress networks
Cally J. Ho, Gayathri Samarasekera, Katharina Rothe, Jing Xu, Kevin C. Yang, Emily Leung, Michelle Chan, Xiaoyan Jiang & Sharon M. Gorski
Pages: 1028-1033
Published online: 07 Jun 2020
AbstractforPuncta intended: connecting the dots between autophagy and cell stress networks | Full Text | References | PDF (292.7 KB) | EPUB
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Autophagic Punctum

Article Commentary
Getting picky with the lysosome membrane
Chan Lee & Michael Overholtzer
Pages: 1034-1036
Published online: 26 Jan 2021
AbstractforGetting picky with the lysosome membrane | Full Text | References | PDF (1.3 MB) | EPUB
  • 1109 Views
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Article Commentary
Introducing secretory reticulophagy/ER-phagy (SERP), a VAMP7-dependent pathway involved in neurite growth
Somya Vats & Thierry Galli
Pages: 1037-1039
Published online: 08 Feb 2021
AbstractforIntroducing secretory reticulophagy/ER-phagy (SERP), a VAMP7-dependent pathway involved in neurite growth | Full Text | References | PDF (1.1 MB) | EPUB
  • 1463 Views
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Article Commentary
No air without autophagy: autophagy is important for lung and swim bladder inflation
Hideaki Morishita, Yuki Kanda & Noboru Mizushima
Pages: 1040-1041
Published online: 08 Feb 2021
AbstractforNo air without autophagy: autophagy is important for lung and swim bladder inflation | Full Text | References | PDF (396.7 KB) | EPUB
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Article Commentary
Mitophagy regulation mediated by the Far complex in yeast
Kentaro Furukawa, Aleksei Innokentev & Tomotake Kanki
Pages: 1042-1043
Published online: 08 Feb 2021
AbstractforMitophagy regulation mediated by the Far complex in yeast | Full Text | References | PDF (779.7 KB) | EPUB
  • 962 Views
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Brief Report
Autophagy-dependent regulation of skeletal muscle regeneration and strength by a RHOGEF
Jae-Sung You & Jie Chen
Pages: 1044-1045
Published online: 21 Feb 2021
AbstractforAutophagy-dependent regulation of skeletal muscle regeneration and strength by a RHOGEF | Full Text | References | PDF (465.4 KB) | EPUB
  • 1143 Views
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Brief Report
Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
Sebastian W. Schultz, Jaime Agudo-Canalejo, Haruka Chino, Simona M. Migliano, Chieko Saito, Ikuko Koyama-Honda, Harald Stenmark, Andreas Brech, Noboru Mizushima, Roland L. Knorr & Alexander I. May
Pages: 1046-1048
Published online: 25 Feb 2021
AbstractforShould I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation | Full Text | References | PDF (400 KB) | EPUB
  • 1919 Views
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Brief Report
Neuronal autophagy controls the axonal endoplasmic reticulum to regulate neurotransmission in healthy neurons
Marijn Kuijpers & Volker Haucke
Pages: 1049-1051
Published online: 25 Feb 2021
AbstractforNeuronal autophagy controls the axonal endoplasmic reticulum to regulate neurotransmission in healthy neurons | Full Text | References | PDF (666.8 KB) | EPUB
  • 1395 Views
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Brief Report
VCP/p97 modulates PtdIns3P production and autophagy initiation
Lidia Wrobel, Sandra M. Hill, Avraham Ashkenazi & David C. Rubinsztein
Pages: 1052-1053
Published online: 09 Mar 2021
AbstractforVCP/p97 modulates PtdIns3P production and autophagy initiation | Full Text | References | PDF (399.9 KB) | EPUB
  • 1602 Views
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Brief Report
Phospho-regulation and function of ULK1-ATG13 during the cell cycle
Zhiyuan Li & Xin Zhang
Pages: 1054-1056
Published online: 17 Mar 2021
AbstractforPhospho-regulation and function of ULK1-ATG13 during the cell cycle | Full Text | References | PDF (428.9 KB) | EPUB
  • 1047 Views
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Article
Selective autophagy tolerates symbiotic bacteria in the Drosophila intestine
Hiroki Nagai & Tamaki Yano
Pages: 1057-1058
Published online: 01 Apr 2021
AbstractforSelective autophagy tolerates symbiotic bacteria in the Drosophila intestine | Full Text | References | PDF (348.4 KB) | EPUB
  • 1617 Views
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Article
Autophagy inhibition perturbs ERBB2 trafficking and abolishes tumorigenesis in ERBB2-driven breast cancer
Mingang Hao, Syn Kok Yeo & Jun-Lin Guan
Pages: 1059-1060
Published online: 28 Mar 2021
AbstractforAutophagy inhibition perturbs ERBB2 trafficking and abolishes tumorigenesis in ERBB2-driven breast cancer | Full Text | References | PDF (214.9 KB) | EPUB
  • 810 Views
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Article Commentary
Conserved role of ENDOG in promoting autophagy
Jianshuang Li, Wenjun Wang & Qinghua Zhou
Pages: 1061-1062
Published online: 28 Mar 2021
AbstractforConserved role of ENDOG in promoting autophagy | Full Text | References | PDF (413.6 KB) | EPUB
  • 1122 Views
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