Citations (223)
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Tingting Liu, Lixia Cao, Tingting Zhang & Huan Fu. (2023) Molecular docking studies, anti-Alzheimer’s disease, antidiabetic, and anti-acute myeloid leukemia potentials of narcissoside. Archives of Physiology and Biochemistry 129:2, pages 405-415.
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Varun Chahal, Sonam Nirwan, Mallika Pathak & Rita Kakkar. (2022) Identification of potent human carbonic anhydrase IX inhibitors: a combination of pharmacophore modeling, 3D-QSAR, virtual screening and molecular dynamics simulations. Journal of Biomolecular Structure and Dynamics 40:10, pages 4516-4531.
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Chandra Bhushan Mishra, Raj Kumar Mongre, Amresh Prakash, Raok Jeon, Claudiu T. Supuran & Myeong-Sok Lee. (2021) Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004): in vitro and in vivo studies. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 954-963.
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Doretta Cuffaro, Elisa Nuti & Armando Rossello. (2020) An overview of carbohydrate-based carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1906-1922.
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Anna Di Fiore, Claudiu T. Supuran, Andrea Scaloni & Giuseppina De Simone. (2020) Human carbonic anhydrases and post-translational modifications: a hidden world possibly affecting protein properties and functions. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1450-1461.
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Ozen Ozensoy Guler, Claudiu. T. Supuran & Clemente Capasso. (2020) Carbonic anhydrase IX as a novel candidate in liquid biopsy. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 255-260.
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Alessio Nocentini & Claudiu T. Supuran. (2019) Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery. Expert Opinion on Drug Discovery 14:11, pages 1175-1197.
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Emma Langella, Vincenzo Alterio, Katia D’Ambrosio, Roberta Cadoni, Jean-Yves Winum, Claudiu T. Supuran, Simona Maria Monti, Giuseppina De Simone & Anna Di Fiore. (2019) Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1498-1505.
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Andrea Angeli, Sonia Del Prete, Mariana Pinteala, Stelian S. Maier, William A. Donald, Bogdan C. Simionescu, Clemente Capasso & Claudiu T. Supuran. (2019) The first activation study of the β-carbonic anhydrases from the pathogenic bacteria Brucella suis and Francisella tularensis with amines and amino acids. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1178-1185.
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Sonia Del Prete, Rosa Merlo, Anna Valenti, Rosanna Mattossovich, Mosè Rossi, Vincenzo Carginale, Claudiu T. Supuran, Giuseppe Perugino & Clemente Capasso. (2019) Thermostability enhancement of the α-carbonic anhydrase from Sulfurihydrogenibium yellowstonense by using the anchoring-and-self-labelling-protein-tag system (ASL). Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 946-954.
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Yosselin Huentupil, Luis Peña, Néstor Novoa, Emanuela Berrino, Rodrigo Arancibia & Claudiu T. Supuran. (2019) New sulfonamides containing organometallic-acylhydrazones: synthesis, characterisation and biological evaluation as inhibitors of human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 451-458.
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Sara Seršen, Katja Traven, Jakob Kljun, Iztok Turel & Claudiu T. Supuran. (2019) Organoruthenium(II) complexes of acetazolamide potently inhibit human carbonic anhydrase isoforms I, II, IX and XII. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 388-393.
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Andrea Angeli, Mariana Pinteala, Stelian S. Maier, Sonia Del Prete, Clemente Capasso, Bogdan C. Simionescu & Claudiu T. Supuran. (2019) Inhibition of bacterial α-, β- and γ-class carbonic anhydrases with selenazoles incorporating benzenesulfonamide moieties. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 244-249.
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Mariantonia Logozzi, Clemente Capasso, Rossella Di Raimo, Sonia Del Prete, Davide Mizzoni, Mario Falchi, Claudiu T. Supuran & Stefano Fais. (2019) Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 272-278.
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Claudiu T. Supuran. (2018) Carbonic anhydrase inhibitors as emerging agents for the treatment and imaging of hypoxic tumors. Expert Opinion on Investigational Drugs 27:12, pages 963-970.
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Claudiu T. Supuran. (2018) Carbonic anhydrase inhibitors and their potential in a range of therapeutic areas. Expert Opinion on Therapeutic Patents 28:10, pages 709-712.
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Claudiu T. Supuran. (2018) Applications of carbonic anhydrases inhibitors in renal and central nervous system diseases. Expert Opinion on Therapeutic Patents 28:10, pages 713-721.
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Alessio Nocentini & Claudiu T. Supuran. (2018) Carbonic anhydrase inhibitors as antitumor/antimetastatic agents: a patent review (2008–2018). Expert Opinion on Therapeutic Patents 28:10, pages 729-740.
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Claudiu T. Supuran & Clemente Capasso. (2018) Biomedical applications of prokaryotic carbonic anhydrases. Expert Opinion on Therapeutic Patents 28:10, pages 745-754.
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Özlen Güzel-Akdemir, Andrea Angeli, Kübra Demir, Claudiu T. Supuran & Atilla Akdemir. (2018) Novel thiazolidinone-containing compounds, without the well-known sulphonamide zinc-binding group acting as human carbonic anhydrase IX inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 1299-1308.
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Emanuela Berrino, Murat Bozdag, Sonia Del Prete, Fatmah A. S. Alasmary, Linah S. Alqahtani, Zeid AlOthman, Clemente Capasso & Claudiu T. Supuran. (2018) Inhibition of α-, β-, γ-, and δ-carbonic anhydrases from bacteria and diatoms with N′-aryl-N-hydroxy-ureas. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 1194-1198.
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Tanvi V. Wani, Silvia Bua, Pravin S. Khude, Abdul H. Chowdhary, Claudiu T. Supuran & Mrunmayee P. Toraskar. (2018) Evaluation of sulphonamide derivatives acting as inhibitors of human carbonic anhydrase isoforms I, II and Mycobacterium tuberculosis β-class enzyme Rv3273. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 962-971.
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Andrea Angeli, Fatmah A. S. Alasmary, Sonia Del Prete, Sameh M. Osman, Zeid AlOthman, William A. Donald, Clemente Capasso & Claudiu T. Supuran. (2018) The first activation study of a δ-carbonic anhydrase: TweCAδ from the diatom Thalassiosira weissflogii is effectively activated by amines and amino acids. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 680-685.
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Fadi M. Awadallah, Silvia Bua, Walaa R. Mahmoud, Hossam H. Nada, Alessio Nocentini & Claudiu T. Supuran. (2018) Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 629-638.
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Claudiu T. Supuran. (2018) Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 485-495.
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Andrea Angeli, Sonia Del Prete, Sameh M. Osman, Fatmah A. S. Alasmary, Zeid AlOthman, William A. Donald, Clemente Capasso & Claudiu T. Supuran. (2018) Activation studies with amines and amino acids of the β-carbonic anhydrase encoded by the Rv3273 gene from the pathogenic bacterium Mycobacterium tuberculosis. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 364-369.
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Andrea Angeli, Sonia Del Prete, Sameh M. Osman, Fatmah A. S. Alasmary, Zeid AlOthman, William A. Donald, Clemente Capasso & Claudiu T. Supuran. (2018) Activation studies of the α- and β-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae with amines and amino acids. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 227-233.
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Vincenzo Alterio, Davide Esposito, Simona Maria Monti, Claudiu T. Supuran & Giuseppina De Simone. (2018) Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 151-157.
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Daniela Vullo, R. Siva Sai Kumar, Andrea Scozzafava, James G. Ferry & Claudiu T. Supuran. (2018) Sulphonamide inhibition studies of the β-carbonic anhydrase from the bacterial pathogen Clostridium perfringens. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 31-36.
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Suleyman Akocak, Nabih Lolak, Daniela Vullo, Mustafa Durgun & Claudiu T. Supuran. (2017) Synthesis and biological evaluation of histamine Schiff bases as carbonic anhydrase I, II, IV, VII, and IX activators. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1305-1312.
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Grazia Luisi, Guido Angelini, Carla Gasbarri, Antonio Laghezza, Mariangela Agamennone, Fulvio Loiodice, Claudiu T. Supuran, Cristina Campestre & Paolo Tortorella. (2017) Dual targeting of cancer-related human matrix metalloproteinases and carbonic anhydrases by chiral N-(biarylsulfonyl)-phosphonic acids. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1260-1264.
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Andrea Angeli, Fabio Vaiano, Francesco Mari, Elisabetta Bertol & Claudiu T. Supuran. (2017) Psychoactive substances belonging to the amphetamine class potently activate brain carbonic anhydrase isoforms VA, VB, VII, and XII. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1253-1259.
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Rajiv Kumar, Vikas Sharma, Silvia Bua, Claudiu T. Supuran & Pawan K. Sharma. (2017) Synthesis and biological evaluation of benzenesulphonamide-bearing 1,4,5-trisubstituted-1,2,3-triazoles possessing human carbonic anhydrase I, II, IV, and IX inhibitory activity. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1187-1194.
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Morteza Abdoli, Andrea Angeli, Murat Bozdag, Fabrizio Carta, Ali Kakanejadifard, Hamid Saeidian & Claudiu T. Supuran. (2017) Synthesis and carbonic anhydrase I, II, VII, and IX inhibition studies with a series of benzo[d]thiazole-5- and 6-sulfonamides. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1071-1078.
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Murat Bozdag, Silvia Bua, Sameh M. Osman, Zeid AlOthman & Claudiu T. Supuran. (2017) Carbonic anhydrase I, II, IV and IX inhibition with a series of 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 885-892.
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Marco Bragagni, Fabrizio Carta, Sameh M. Osman, Zeid AlOthman & Claudiu T. Supuran. (2017) Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 701-706.
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Erol Licsandru, Muhammet Tanc, Istvan Kocsis, Mihail Barboiu & Claudiu T. Supuran. (2017) A class of carbonic anhydrase I – selective activators. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 37-46.
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Ebru Mete, Birnur Comez, Halise Inci Gul, Ilhami Gulcin & Claudiu T. Supuran. (2016) Synthesis and carbonic anhydrase inhibitory activities of new thienyl-substituted pyrazoline benzenesulfonamides. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup2, pages 1-5.
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F. Zehra Küçükbay, Hasan Küçükbay, Muhammet Tanc & Claudiu T. Supuran. (2016) Synthesis and carbonic anhydrase I, II, IV and XII inhibitory properties of N-protected amino acid – sulfonamide conjugates. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 1476-1483.
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Erhan Başar, Ekrem Tunca, Metin Bülbül & Muharrem Kaya. (2016) Synthesis of novel sulfonamides under mild conditions with effective inhibitory activity against the carbonic anhydrase isoforms I and II. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 1356-1361.
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Burak Aday, Pınar Sola, Ferdağ Çolak & Muharrem Kaya. (2016) Synthesis of novel sulfonamide analogs containing sulfamerazine/sulfaguanidine and their biological activities. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 1005-1010.
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Cristina Federici, Luana Lugini, Maria Lucia Marino, Fabrizio Carta, Elisabetta Iessi, Tommaso Azzarito, Claudiu T. Supuran & Stefano Fais. (2016) Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup1, pages 119-125.
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Claudiu T. Supuran. (2016) CA IX stratification based on cancer treatment: a patent evaluation of US2016/0002350. Expert Opinion on Therapeutic Patents 26:10, pages 1105-1109.
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Viviana De Luca, Sonia Del Prete, Daniela Vullo, Vincenzo Carginale, Pietro Di Fonzo, Sameh M Osman, Zeid AlOthman, Claudiu T Supuran & Clemente Capasso. (2016) Expression and characterization of a recombinant psychrophilic γ-carbonic anhydrase (NcoCA) identified in the genome of the Antarctic cyanobacteria belonging to the genus Nostoc. Journal of Enzyme Inhibition and Medicinal Chemistry 31:5, pages 810-817.
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Ozen Ozensoy Guler, Clemente Capasso & Claudiu T. Supuran. (2016) A magnificent enzyme superfamily: carbonic anhydrases, their purification and characterization. Journal of Enzyme Inhibition and Medicinal Chemistry 31:5, pages 689-694.
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Claudiu T. Supuran. (2016) Carbonic anhydrase inhibition and the management of neuropathic pain. Expert Review of Neurotherapeutics 16:8, pages 961-968.
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Claudiu T. Supuran. (2016) How many carbonic anhydrase inhibition mechanisms exist?. Journal of Enzyme Inhibition and Medicinal Chemistry 31:3, pages 345-360.
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Claudiu T. Supuran. (2016) Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 12:4, pages 423-431.
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Murat Bozdag, Fabrizio Carta, Daniela Vullo, Semra Isik, Zeid AlOthman, Sameh M. Osman, Andrea Scozzafava & Claudiu T. Supuran. (2016) Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae β-carbonic anhydrase. Journal of Enzyme Inhibition and Medicinal Chemistry 31:1, pages 132-136.
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Andrea Scozzafava, Pınar Kalın, Claudiu T. Supuran, İlhami Gülçin & Saleh H. Alwasel. (2015) The impact of hydroquinone on acetylcholine esterase and certain human carbonic anhydrase isoenzymes (hCA I, II, IX, and XII). Journal of Enzyme Inhibition and Medicinal Chemistry 30:6, pages 941-946.
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Namrata Singasane, Prashant S. Kharkar, Mariangela Ceruso, Claudiu T. Supuran & Mrunmayee P. Toraskar. (2015) Inhibition of carbonic anhydrase isoforms I, II, IX and XII with Schiff’s bases incorporating iminoureido moieties. Journal of Enzyme Inhibition and Medicinal Chemistry 30:6, pages 901-907.
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Daniela Vullo, Semra Isik, Murat Bozdag, Fabrizio Carta & Claudiu T. Supuran. (2015) 7-Amino-3,4-dihydro-1H-quinolin-2-one, a compound similar to the substituted coumarins, inhibits α-carbonic anhydrases without hydrolysis of the lactam ring. Journal of Enzyme Inhibition and Medicinal Chemistry 30:5, pages 773-777.
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Claudiu T Supuran. (2015) Acetazolamide for the treatment of idiopathic intracranial hypertension. Expert Review of Neurotherapeutics 15:8, pages 851-856.
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Andrea Scozzafava, Maurizio Passaponti, Claudiu T. Supuran & İlhami Gülçin. (2015) Carbonic anhydrase inhibitors: guaiacol and catechol derivatives effectively inhibit certain human carbonic anhydrase isoenzymes (hCA I, II, IX and XII). Journal of Enzyme Inhibition and Medicinal Chemistry 30:4, pages 586-591.
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Ahmed M. Alafeefy, Hatem A. Abdel-Aziz, F. Carta, Claudiu T. Supuran, Shilendra K. Pathak, Onkar Prasad & Leena Sinha. (2015) Exploring QSARs of some benzenesulfonamides incorporating cyanoacrylamide moieties as a carbonic anhydrase inhibitors (specifically against tumor-associated isoforms IX and XII). Journal of Enzyme Inhibition and Medicinal Chemistry 30:4, pages 519-523.
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Claudiu T Supuran & Jean-Yves Winum. (2015) Designing carbonic anhydrase inhibitors for the treatment of breast cancer. Expert Opinion on Drug Discovery 10:6, pages 591-597.
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Håkon Reikvam, Michelle Hauge, Annette K Brenner, Kimberley Joanne Hatfield & Øystein Bruserud. (2015) Emerging therapeutic targets for the treatment of human acute myeloid leukemia (part 1) – gene transcription, cell cycle regulation, metabolism and intercellular communication. Expert Review of Hematology 8:3, pages 299-313.
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Claudia Palmer & Claudiu T Supuran. (2015) A Key Opinion Leader interview: insight into the research and career of Prof. Claudiu T Supuran. Expert Opinion on Therapeutic Patents 25:4, pages 501-505.
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Aamer Saeed, Mariya al-Rashida, Mehwish Hamayoun, Amara Mumtaz & Jamshed Iqbal. (2014) Carbonic anhydrase inhibition by 1-aroyl-3-(4-aminosulfonylphenyl)thioureas. Journal of Enzyme Inhibition and Medicinal Chemistry 29:6, pages 901-905.
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Shalini Singh & Claudiu T. Supuran. (2014) Chemometric modeling of breast cancer associated carbonic anhydrase IX inhibitors belonging to the ureido-substituted benzene sulfonamide class. Journal of Enzyme Inhibition and Medicinal Chemistry 29:6, pages 877-883.
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Antonin Lamaziere, Claude Wolf & Peter J Quinn. (2014) How lipidomics provides new insight into drug discovery. Expert Opinion on Drug Discovery 9:7, pages 819-836.
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Erik R Swenson. (2014) Safety of carbonic anhydrase inhibitors. Expert Opinion on Drug Safety 13:4, pages 459-472.
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Mehtap Tugrak, Halise Inci Gul, Yeliz Demir & Ilhami Gulcin. (2020) Synthesis of benzamide derivatives with thiourea‐substituted benzenesulfonamides as carbonic anhydrase inhibitors. Archiv der Pharmazie 354:2, pages 2000230.
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Aparna Das & Bimal Krishna Banik. 2021. Microwaves in Chemistry Applications. Microwaves in Chemistry Applications
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Agostino Bruno & Gabriele Costantino. 2021. pH-Interfering Agents as Chemosensitizers in Cancer Therapy. pH-Interfering Agents as Chemosensitizers in Cancer Therapy
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Zuhal Alım, Zeynep Köksal & Muhammet Karaman. (2020) Evaluation of some thiophene-based sulfonamides as potent inhibitors of carbonic anhydrase I and II isoenzymes isolated from human erythrocytes by kinetic and molecular modelling studies. Pharmacological Reports 72:6, pages 1738-1748.
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Andrea Angeli, Fabrizio Carta, Alessio Nocentini, Jean-Yves Winum, Raivis Zalubovskis, Atilla Akdemir, Valentina Onnis, Wagdy M. Eldehna, Clemente Capasso, Giuseppina De Simone, Simona Maria Monti, Simone Carradori, William A. Donald, Shoukat Dedhar & Claudiu T. Supuran. (2020) Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment. Metabolites 10:10, pages 412.
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Azizah M. Malebari, Tarek S. Ibrahim, Ibrahim M. Salem, Ismail Salama, Ahdab N. Khayyat, Samia M. Mostafa, Osama I. El-Sabbagh & Khaled M. Darwish. (2020) The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme. Pharmaceuticals 13:9, pages 252.
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Mert O. Karataş, Samir A. A. Noma, Canbolat Gürses, Sevgi Balcıoğlu, Burhan Ateş, Bülent Alıcı & Ümit Çakır. (2020) Water Soluble Coumarin Quaternary Ammonium Chlorides: Synthesis and Biological Evaluation. Chemistry & Biodiversity.
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Giosuè Costa, Annalisa Maruca, Roberta Rocca, Francesca Alessandra Ambrosio, Emanuela Berrino, Fabrizio Carta, Francesco Mesiti, Alessandro Salatino, Delia Lanzillotta, Francesco Trapasso, Anna Artese, Stefano Alcaro & Claudiu T. Supuran. (2020) In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition. Antioxidants 9:9, pages 775.
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Aiten M. Soliman, Mostafa M. Ghorab, Silvia Bua & Claudiu T. Supuran. (2020) Iodoquinazolinones bearing benzenesulfonamide as human carbonic anhydrase I, II, IX and XII inhibitors: Synthesis, biological evaluation and radiosensitizing activity. European Journal of Medicinal Chemistry 200, pages 112449.
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Chaofu Yang, Jing Wang, Yunyun Cheng, Xu Yang, Yan Feng, Xiaomei Zhuang, Zhenwang Li, Wangyu Zhao, Jiwen Zhang, Xianyu Sun & Xinhua He. (2020) N-Quinary heterocycle-4-sulphamoylbenzamides exert anti-hypoxic effects as dual inhibitors of carbonic anhydrases I/II. Bioorganic Chemistry 100, pages 103931.
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Francesca Mancuso, Anna Di Fiore, Laura De Luca, Andrea Angeli, Simona M. Monti, Giuseppina De Simone, Claudiu T. Supuran & Rosaria Gitto. (2020) Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms. ACS Medicinal Chemistry Letters 11:5, pages 1000-1005.
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Jyoti Singh Tomar & Jun Shen. (2020) Characterization of Carbonic Anhydrase In Vivo Using Magnetic Resonance Spectroscopy. International Journal of Molecular Sciences 21:7, pages 2442.
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Adem ERGÜN & Mert Olgun KARATAŞ. (2020) Synthesis, characterization, and inhibitory properties of novel N-benzylbenzimidazole-silver(I) complexes on carbonic anhydrase and polyphenol oxidase enzymes. Journal of the Institute of Science and Technology, pages 320-327.
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Heba T. Abdel-Mohsen, Ahmed M. El Kerdawy, Mohamed A. Omar, Emanuela Berrino, Ahmed S. Abdelsamie, Hoda I. El Diwani & Claudiu T. Supuran. (2020) New thiopyrimidine-benzenesulfonamide conjugates as selective carbonic anhydrase II inhibitors: synthesis, in vitro biological evaluation, and molecular docking studies. Bioorganic & Medicinal Chemistry 28:5, pages 115329.
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Claudiu T. Supuran & Clemente Capasso. 2020. Physiological and Biotechnological Aspects of Extremophiles. Physiological and Biotechnological Aspects of Extremophiles
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Vincenzo Alterio, Markus Kellner, Davide Esposito, Friederike Liesche-Starnecker, Silvia Bua, Claudiu T. Supuran, Simona Maria Monti, Reinhard Zeidler & Giuseppina De Simone. (2019) Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex. Journal of Molecular Biology 431:24, pages 4910-4921.
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Cem Yamali, Halise Inci Gul, Abdulilah Ece, Silvia Bua, Andrea Angeli, Hiroshi Sakagami, Ertan Sahin & Claudiu T. Supuran. (2019) Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors. Bioorganic Chemistry 92, pages 103222.
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Mert Ogun KARATAŞ & Adem Ergün. (2019) Synthesis, Characterization, and Carbonic Anhydrase Inhibitory Properties of Silver(I) Complexes of Benzimidazole Derivatives. Journal of the Turkish Chemical Society, Section A: Chemistry, pages 253-260.
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Farzaneh Mohebali, Zahrasadat Nazifi, Seyed Mohamad Reza Nazifi, Hossein Mohammadian & Ahmad R. Massah. (2019) Synthesis, molecular docking studies, and absorption, distribution, metabolism, and excretion prediction of novel sulfonamide derivatives as antibacterial agents. Journal of the Chinese Chemical Society 66:5, pages 558-566.
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Nabih Lolak, Suleyman Akocak, Silvia Bua, Rajesh K.K. Sanku & Claudiu T. Supuran. (2019) Discovery of new ureido benzenesulfonamides incorporating 1,3,5-triazine moieties as carbonic anhydrase I, II, IX and XII inhibitors. Bioorganic & Medicinal Chemistry 27:8, pages 1588-1594.
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Alessandro Sannino, Elena Gabriele, Martina Bigatti, Sara Mulatto, Jacopo Piazzi, Jörg Scheuermann, Dario Neri, Etienne J. Donckele & Florent Samain. (2019) Quantitative Assessment of Affinity Selection Performance by Using DNA‐Encoded Chemical Libraries. ChemBioChem 20:7, pages 955-962.
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Özgül Karlık, Nahit Gençer, Mert O. Karataş, Adem Ergün, Kübra Çıkrıkcı, Oktay Arslan, Bülent Alıcı, Işın Kılıç‐Cıkla & Namık Özdemir. (2019)
Microwave‐assisted synthesis of 1‐substituted‐1
H
‐benzimidazolium salts: Non‐competitive inhibition of human carbonic anhydrase I and II
. Archiv der Pharmazie 352:4, pages 1800325.
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Kerem Buran, Silvia Bua, Giulio Poli, F. Önen Bayram, Tiziano Tuccinardi & Claudiu T. Supuran. (2019) Novel 8-Substituted Coumarins That Selectively Inhibit Human Carbonic Anhydrase IX and XII. International Journal of Molecular Sciences 20:5, pages 1208.
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Maria Rosa Buemi, Anna Di Fiore, Laura De Luca, Andrea Angeli, Francesca Mancuso, Stefania Ferro, Simona Maria Monti, Martina Buonanno, Emilio Russo, Giovanbattista De Sarro, Giuseppina De Simone, Claudiu T. Supuran & Rosaria Gitto. (2019) Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. European Journal of Medicinal Chemistry 163, pages 443-452.
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Nabih Lolak, Suleyman Akocak, Silvia Bua & Claudiu T. Supuran. (2019) Design, synthesis and biological evaluation of novel ureido benzenesulfonamides incorporating 1,3,5-triazine moieties as potent carbonic anhydrase IX inhibitors. Bioorganic Chemistry 82, pages 117-122.
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Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Alessio Nocentini, Radwan S. El-Haggar, Silvia Bua, Alessandro Bonardi, Sara T. Al-Rashood, Ghada S. Hassan, Paola Gratteri, Hatem A. Abdel-Aziz & Claudiu T. Supuran. (2019) Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents. European Journal of Medicinal Chemistry 162, pages 147-160.
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Claudiu T. Supuran. 2019. Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders. Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders
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Clemente Capasso & Mihail Barboiu. 2019. Carbonic Anhydrases. Carbonic Anhydrases
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Patrizio Blandina & Claudiu T. Supuran. 2019. Carbonic Anhydrases. Carbonic Anhydrases
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Alessio Nocentini & Claudiu T. Supuran. 2019. Carbonic Anhydrases. Carbonic Anhydrases
3
16
.
Zhuzhou Shao, Wei Liu, Huimin Tao, Fang Liu, Ruxin Zeng, Pier Alexandre Champagne, Yang Cao, K. N. Houk & Yong Liang. (2018) Bioorthogonal release of sulfonamides and mutually orthogonal liberation of two drugs. Chemical Communications 54:100, pages 14089-14092.
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Anyaporn Sangkaew, Jerapan Krungkrai & Chulee Yompakdee. (2018) Development of a high throughput yeast-based screening assay for human carbonic anhydrase isozyme II inhibitors. AMB Express 8:1.
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Alaa A.-M. Abdel-Aziz, Adel S. El-Azab, Mohamed A. Abu El-Enin, Abdulrahman A. Almehizia, Claudiu T. Supuran & Alessio Nocentini. (2018) Synthesis of novel isoindoline-1,3-dione-based oximes and benzenesulfonamide hydrazones as selective inhibitors of the tumor-associated carbonic anhydrase IX. Bioorganic Chemistry 80, pages 706-713.
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Andrea Angeli, Sonia Del Prete, Fatmah A.S. Alasmary, Linah S. Alqahtani, Zeid AlOthman, William A. Donald, Clemente Capasso & Claudiu T. Supuran. (2018) The first activation studies of the η-carbonic anhydrase from the malaria parasite Plasmodium falciparum with amines and amino acids. Bioorganic Chemistry 80, pages 94-98.
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Prashant Mujumdar, Silvia Bua, Claudiu T. Supuran, Thomas S. Peat & Sally-Ann Poulsen. (2018) Synthesis, structure and bioactivity of primary sulfamate-containing natural products. Bioorganic & Medicinal Chemistry Letters 28:17, pages 3009-3013.
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Emma Langella, Martina Buonanno, Daniela Vullo, Nina Dathan, Marilisa Leone, Claudiu T. Supuran, Giuseppina De Simone & Simona Maria Monti. (2018) Biochemical, biophysical and molecular dynamics studies on the proteoglycan-like domain of carbonic anhydrase IX. Cellular and Molecular Life Sciences 75:17, pages 3283-3296.
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Claudiu T. Supuran, Vincenzo Alterio, Anna Di Fiore, Katia D’ Ambrosio, Fabrizio Carta, Simona Maria Monti & Giuseppina De Simone. (2018) Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one. Medicinal Research Reviews 38:6, pages 1799-1836.
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Andrea Angeli, Marianne Kuuslahti, Seppo Parkkila & Claudiu T. Supuran. (2018) Activation studies with amines and amino acids of the α-carbonic anhydrase from the pathogenic protozoan Trypanosoma cruzi. Bioorganic & Medicinal Chemistry 26:14, pages 4187-4190.
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Andrea Angeli, William A. Donald, Seppo Parkkila & Claudiu T. Supuran. (2018) Activation studies with amines and amino acids of the β-carbonic anhydrase from the pathogenic protozoan Leishmania donovani chagasi. Bioorganic Chemistry 78, pages 406-410.
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Halise Inci Gul, Cem Yamali, Merve Bulbuller, Petek Ballar Kirmizibayrak, Mustafa Gul, Andrea Angeli, Silvia Bua & Claudiu T. Supuran. (2018) Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes. Bioorganic Chemistry 78, pages 290-297.
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Jahanzaib Arshad, Muhammad Hanif, Ayesha Zafar, Sanam Movassaghi, Kelvin K. H. Tong, Jóhannes Reynisson, Mario Kubanik, Amir Waseem, Tilo Söhnel, Stephen M. F. Jamieson & Christian G. Hartinger. (2018) Organoruthenium and Organoosmium Complexes of 2-Pyridinecarbothioamides Functionalized with a Sulfonamide Motif: Synthesis, Cytotoxicity and Biomolecule Interactions. ChemPlusChem 83:7, pages 612-619.
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Morteza Abdoli, Murat Bozdag, Andrea Angeli & Claudiu Supuran. (2018) Benzamide-4-Sulfonamides Are Effective Human Carbonic Anhydrase I, II, VII, and IX Inhibitors. Metabolites 8:2, pages 37.
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Niccolò Chiaramonte, Maria Romanelli, Elisabetta Teodori & Claudiu Supuran. (2018) Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors. Metabolites 8:2, pages 36.
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Silvia Bua, Manisha Tiwari & Claudiu T. Supuran. (2018) Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation. Journal of Medicinal Chemistry 61:7, pages 3151-3165.
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Nabih Lolak, Suleyman Akocak, Silvia Bua, Murat Koca & Claudiu T. Supuran. (2018) Design and synthesis of novel 1,3-diaryltriazene-substituted sulfonamides as potent and selective carbonic anhydrase II inhibitors. Bioorganic Chemistry 77, pages 542-547.
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Alessio Nocentini, Davide Moi, Gianfranco Balboni, Valentina Onnis & Claudiu T. Supuran. (2018) Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors. Bioorganic Chemistry 77, pages 293-299.
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Halise Inci Gul, Cem Yamali, Hiroshi Sakagami, Andrea Angeli, Janis Leitans, Andris Kazaks, Kaspars Tars, Dilan Ozmen Ozgun & Claudiu T. Supuran. (2018) New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors. Bioorganic Chemistry 77, pages 411-419.
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Andrea Angeli, Sonia Del Prete, William A. Donald, Clemente Capasso & Claudiu T. Supuran. (2018) The γ-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae is potently activated by amines and amino acids. Bioorganic Chemistry 77, pages 1-5.
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Burak Aday, Ramazan Ulus, Muhammet Tanç, Muharrem Kaya & Claudiu T. Supuran. (2018) Synthesis of novel 5-amino-1,3,4-thiadiazole-2-sulfonamide containing acridine sulfonamide/carboxamide compounds and investigation of their inhibition effects on human carbonic anhydrase I, II, IV and VII. Bioorganic Chemistry 77, pages 101-105.
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Claudiu Supuran. (2018) Carbonic Anhydrases and Metabolism. Metabolites 8:2, pages 25.
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Claudiu T Supuran. (2018) Carbonic anhydrase activators. Future Medicinal Chemistry 10:5, pages 561-573.
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Alessandro Bonardi, Matteo Falsini, Daniela Catarzi, Flavia Varano, Lorenzo Di Cesare Mannelli, Barbara Tenci, Carla Ghelardini, Andrea Angeli, Claudiu T. Supuran & Vittoria Colotta. (2018) Structural investigations on coumarins leading to chromeno[4,3-c]pyrazol-4-ones and pyrano[4,3-c]pyrazol-4-ones: New scaffolds for the design of the tumor-associated carbonic anhydrase isoforms IX and XII. European Journal of Medicinal Chemistry 146, pages 47-59.
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Leonardo E. Riafrecha, Silvia Bua, Claudiu T. Supuran & Pedro A. Colinas. (2018) Improving the carbonic anhydrase inhibition profile of the sulfamoylphenyl pharmacophore by attachment of carbohydrate moieties. Bioorganic Chemistry 76, pages 61-66.
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Ramazan Ulus, İbrahim Esirden, Burak Aday, Gurbet Çelik Turgut, Alaattin Şen & Muharrem Kaya. (2017) Synthesis of novel acridine-sulfonamide hybrid compounds as acetylcholinesterase inhibitor for the treatment of alzheimer’s disease. Medicinal Chemistry Research 27:2, pages 634-641.
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Aikaterini Peperidou, Silvia Bua, Murat Bozdag, Dimitra Hadjipavlou-Litina & Claudiu Supuran. (2018) Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX. Molecules 23:1, pages 153.
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Yan Zhang, Claudiu T. Supuran & Mihail Barboiu. (2018) Exponential Activation of Carbonic Anhydrase by Encapsulation in Dynameric Host Matrices with Chiral Discrimination. Chemistry - A European Journal 24:3, pages 715-720.
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Alessio Nocentini, Silvia Bua, Carrie L. Lomelino, Robert McKenna, Marta Menicatti, Gianluca Bartolucci, Barbara Tenci, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Paola Gratteri & Claudiu T. Supuran. (2017) Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases. ACS Medicinal Chemistry Letters 8:12, pages 1314-1319.
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Reza Bayat Mokhtari, Narges Baluch, Micky Ka Hon Tsui, Sushil Kumar, Tina S. Homayouni, Karen Aitken, Bikul Das, Sylvain Baruchel & Herman Yeger. (2017) Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma. BMC Cancer 17:1.
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Justina Kazokaitė, Ashok Aspatwar, Seppo Parkkila & Daumantas Matulis. (2017) An update on anticancer drug development and delivery targeting carbonic anhydrase IX. PeerJ 5, pages e4068.
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Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Alessio Nocentini, Paola Gratteri, Ibrahim H. Eissa, Mohamed Fares, Omnia E. Ismael, Hazem A. Ghabbour, Mahmoud M. Elaasser, Hatem A. Abdel-Aziz & Claudiu T. Supuran. (2017) Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies. European Journal of Medicinal Chemistry 139, pages 250-262.
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Srinivas Angapelly, P.V. Sri Ramya, Andrea Angeli, Sonia Del Prete, Clemente Capasso, Mohammed Arifuddin & Claudiu T. Supuran. (2017) Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors. Bioorganic & Medicinal Chemistry 25:20, pages 5726-5732.
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Claudiu Supuran. (2017) Special Issue: Sulfonamides. Molecules 22:10, pages 1642.
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Andrea Angeli, Fabrizio Carta, Gianluca Bartolucci & Claudiu T. Supuran. (2017) Synthesis of novel acyl selenoureido benzensulfonamides as carbonic anhydrase I, II, VII and IX inhibitors. Bioorganic & Medicinal Chemistry 25:13, pages 3567-3573.
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Martina Buonanno, Emma Langella, Nicola Zambrano, Mariangela Succoio, Emanuele Sasso, Vincenzo Alterio, Anna Di Fiore, Annamaria Sandomenico, Claudiu T. Supuran, Andrea Scaloni, Simona Maria Monti & Giuseppina De Simone. (2017) Disclosing the Interaction of Carbonic Anhydrase IX with Cullin-Associated NEDD8-Dissociated Protein 1 by Molecular Modeling and Integrated Binding Measurements. ACS Chemical Biology 12:6, pages 1460-1465.
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Suleyman Akocak, Nabih Lolak, Alessio Nocentini, Gulcin Karakoc, Anzel Tufan & Claudiu T. Supuran. (2017) Synthesis and biological evaluation of novel aromatic and heterocyclic bis-sulfonamide Schiff bases as carbonic anhydrase I, II, VII and IX inhibitors. Bioorganic & Medicinal Chemistry 25:12, pages 3093-3097.
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Elvira Bruno, Maria Rosa Buemi, Anna Di Fiore, Laura De Luca, Stefania Ferro, Andrea Angeli, Roberto Cirilli, Daniele Sadutto, Vincenzo Alterio, Simona Maria Monti, Claudiu T. Supuran, Giuseppina De Simone & Rosaria Gitto. (2017) Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides. Journal of Medicinal Chemistry 60:10, pages 4316-4326.
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Fabrizio Carta, Daniela Vullo, Sameh M. Osman, Zeid AlOthman & Claudiu T. Supuran. (2017) Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs. Bioorganic & Medicinal Chemistry 25:9, pages 2569-2576.
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Fabrizio Carta, Alexander Birkmann, Tamara Pfaff, Helmut Buschmann, Wilfried Schwab, Holger Zimmermann, Alfonso Maresca & Claudiu T. Supuran. (2017) Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action. Journal of Medicinal Chemistry 60:7, pages 3154-3164.
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Menshawy A. Mohamed, Alaa A.-M. Abdel-Aziz, Helmy M. Sakr, Adel S. El-Azab, Silvia Bua & Claudiu T. Supuran. (2017) Synthesis and human/bacterial carbonic anhydrase inhibition with a series of sulfonamides incorporating phthalimido moieties. Bioorganic & Medicinal Chemistry 25:8, pages 2524-2529.
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Andrea Angeli, Damiano Tanini, Caterina Viglianisi, Lucia Panzella, Antonella Capperucci, Stefano Menichetti & Claudiu T. Supuran. (2017) Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors. Bioorganic & Medicinal Chemistry 25:8, pages 2518-2523.
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Mohamed Fares, Radwa A. Eladwy, Alessio Nocentini, Soha R. Abd El Hadi, Hazem A. Ghabbour, Ashraf Abdel-Megeed, Wagdy M. Eldehna, Hatem A. Abdel-Aziz & Claudiu T. Supuran. (2017) Synthesis of bulky-tailed sulfonamides incorporating pyrido[2,3- d ][1,2,4]triazolo[4,3- a ]pyrimidin-1(5H)-yl) moieties and evaluation of their carbonic anhydrases I, II, IV and IX inhibitory effects. Bioorganic & Medicinal Chemistry 25:7, pages 2210-2217.
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Yann Le Duc, Erol Licsandru, Daniela Vullo, Mihail Barboiu & Claudiu T. Supuran. (2017) Carbonic anhydrases activation with 3-amino-1H-1,2,4-triazole-1-carboxamides: Discovery of subnanomolar isoform II activators. Bioorganic & Medicinal Chemistry 25:5, pages 1681-1686.
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Simon J.A. van Kuijk, Nanda Kumar Parvathaneni, Raymon Niemans, Marike W. van Gisbergen, Fabrizio Carta, Daniela Vullo, Silvia Pastorekova, Ala Yaromina, Claudiu T. Supuran, Ludwig J. Dubois, Jean-Yves Winum & Philippe Lambin. (2017) New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs. European Journal of Medicinal Chemistry 127, pages 691-702.
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Ramazan Ulus, Belma Zengin Kurt, Isil Gazioğlu & Muharrem Kaya. (2017) Microwave assisted synthesis of novel hybrid tacrine-sulfonamide derivatives and investigation of their antioxidant and anticholinesterase activities. Bioorganic Chemistry 70, pages 245-255.
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Asta Zubrienė, Alexey Smirnov, Virginija Dudutienė, David D. Timm, Jurgita Matulienė, Vilma Michailovienė, Audrius Zakšauskas, Elena Manakova, Saulius Gražulis & Daumantas Matulis. (2017) Intrinsic Thermodynamics and Structures of 2,4- and 3,4-Substituted Fluorinated Benzenesulfonamides Binding to Carbonic Anhydrases. ChemMedChem 12:2, pages 161-176.
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İbrahim Esirden, Muhammet Tanç, Claudiu T. Supuran & Muharrem Kaya. (2017) Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII. Bioorganic & Medicinal Chemistry Letters 27:1, pages 86-89.
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Srinivas Angapelly, P.V. Sri Ramya, Andrea Angeli, Simona Maria Monti, Martina Buonanno, Mallika Alvala, Cladiu T. Supuran & Mohammed Arifuddin. (2017) Discovery of 4-sulfamoyl-phenyl-β-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors. Bioorganic & Medicinal Chemistry 25:2, pages 539-544.
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Kęstutis Rutkauskas, Asta Zubrienė, Ingrida Tumosienė, Kristina Kantminienė, Vytautas Mickevičius & Daumantas Matulis. (2016) Benzenesulfonamides bearing pyrrolidinone moiety as inhibitors of carbonic anhydrase IX: synthesis and binding studies. Medicinal Chemistry Research 26:1, pages 235-246.
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Joanna Kopecka, Gregory M. Rankin, Iris C. Salaroglio, Sally-Ann Poulsen & Chiara Riganti. (2016) P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors. Oncotarget 7:52, pages 85861-85875.
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Alessio Nocentini, Marta Ferraroni, Fabrizio Carta, Mariangela Ceruso, Paola Gratteri, Cecilia Lanzi, Emanuela Masini & Claudiu T. Supuran. (2016) Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations. Journal of Medicinal Chemistry 59:23, pages 10692-10704.
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Murat Bozdag, Ahmed M. Alafeefy, Fabrizio Carta, Mariangela Ceruso, Abdul-Malek S. Al-Tamimi, Abdulla A. Al-Kahtani, Fatmah A.S. Alasmary & Claudiu T. Supuran. (2016) Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties. Bioorganic & Medicinal Chemistry 24:18, pages 4100-4107.
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Clara Aceves-Luquero, Cristina Galiana-Roselló, Guillem Ramis, Ruth Villalonga-Planells, Enrique García-España, Silvia Fernández de Mattos, Rafael Peláez, José M. Llinares, M. Eugenia González-Rosende & Priam Villalonga. (2016) N-(2-methyl-indol-1H-5-yl)-1-naphthalenesulfonamide: A novel reversible antimitotic agent inhibiting cancer cell motility. Biochemical Pharmacology 115, pages 28-42.
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Simon J. A. van Kuijk, Roben G. Gieling, Raymon Niemans, Natasja G. Lieuwes, Rianne Biemans, Brian A. Telfer, Guido R. M. M. Haenen, Ala Yaromina, Philippe Lambin, Ludwig J. Dubois & Kaye J. Williams. (2016) The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy. PLOS ONE 11:8, pages e0161040.
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Ramazan Ulus, Burak Aday, Muhammet Tanç, Claudiu T. Supuran & Muharrem Kaya. (2016) Microwave assisted synthesis of novel acridine–acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII. Bioorganic & Medicinal Chemistry 24:16, pages 3548-3555.
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Claudiu T. Supuran. (2016) Structure and function of carbonic anhydrases. Biochemical Journal 473:14, pages 2023-2032.
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Erik Hanff, Anke Böhmer, Maximilian Zinke, Stepan Gambaryan, Alexandra Schwarz, Claudiu T. Supuran & Dimitrios Tsikas. (2016) Carbonic anhydrases are producers of S-nitrosothiols from inorganic nitrite and modulators of soluble guanylyl cyclase in human platelets. Amino Acids 48:7, pages 1695-1706.
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Eric Hansen, Elaine Limé, Per-Ola Norrby & Olaf Wiest. (2016) Anomeric Effects in Sulfamides. The Journal of Physical Chemistry A 120:20, pages 3677-3682.
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Simon J. A. van Kuijk, Ala Yaromina, Ruud Houben, Raymon Niemans, Philippe Lambin & Ludwig J. Dubois. (2016) Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: A Meta-Analysis. Frontiers in Oncology 6.
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Joseph Lau, Zhengxing Zhang, Silvia Jenni, Hsiou-Ting Kuo, Zhibo Liu, Daniela Vullo, Claudiu T. Supuran, Kuo-Shyan Lin & François Bénard. (2016)
PET Imaging of Carbonic Anhydrase IX Expression of HT-29 Tumor Xenograft Mice with
68
Ga-Labeled Benzenesulfonamides
. Molecular Pharmaceutics 13:3, pages 1137-1146.
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Adnan Ashraf, Waseeq Ahmad Siddiqui, Jamshed Akbar, Ghulam Mustafa, Harald Krautscheid, Nazif Ullah, Bushra Mirza, Falak Sher, Muhammad Hanif & Christian G. Hartinger. (2016) Metal complexes of benzimidazole derived sulfonamide: Synthesis, molecular structures and antimicrobial activity. Inorganica Chimica Acta 443, pages 179-185.
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Wagdy M. Eldehna, Mohamed Fares, Mariangela Ceruso, Hazem A. Ghabbour, Sahar M. Abou-Seri, Hatem A. Abdel-Aziz, Dalal A. Abou El Ella & Claudiu T. Supuran. (2016) Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII. European Journal of Medicinal Chemistry 110, pages 259-266.
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Ahmed M. Alafeefy, Fabrizio Carta, Mariangela Ceruso, Abdul-Malek S. Al-Tamimi, Abdulla A. Al-Kahtani & Claudiu T. Supuran. (2016) Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma. Bioorganic & Medicinal Chemistry 24:6, pages 1402-1407.
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Ahmed M. Alafeefy, Rehan Ahmad, Maha Abdulla, Wagdy M. Eldehna, Abdul-Malek S. Al-Tamimi, Hatem A. Abdel-Aziz, Omar Al-Obaid, Fabrizio Carta, Abdulla A. Al-Kahtani & Claudiu T. Supuran. (2016) Development of certain new 2-substituted-quinazolin-4-yl-aminobenzenesulfonamide as potential antitumor agents. European Journal of Medicinal Chemistry 109, pages 247-253.
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Benedetta Cornelio, Marie Laronze-Cochard, Mariangela Ceruso, Marta Ferraroni, Graham A. RanceFabrizio Carta, Andrei N. KhlobystovAntonella Fontana, Claudiu T. Supuran & Janos Sapi. (2016) 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki–Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies. Journal of Medicinal Chemistry 59:2, pages 721-732.
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Marta Ferraroni, Fabrizio Carta, Andrea Scozzafava & Claudiu T. Supuran. (2015) Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins. Journal of Medicinal Chemistry 59:1, pages 462-473.
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Ylenia Cau, Mattia Mori, Claudiu T. Supuran & Maurizio Botta. (2016) Mycobacterial carbonic anhydrase inhibition with phenolic acids and esters: kinetic and computational investigations. Organic & Biomolecular Chemistry 14:35, pages 8322-8330.
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Vittorio Canale, Rafał Kurczab, Anna Partyka, Grzegorz Satała, Karolina Słoczyńska, Tomasz Kos, Magdalena Jastrzębska-Więsek, Agata Siwek, Elżbieta Pękala, Andrzej J. Bojarski, Anna Wesołowska, Piotr Popik & Paweł Zajdel. (2016) N-Alkylated arylsulfonamides of (aryloxy)ethyl piperidines: 5-HT7 receptor selectivity versus multireceptor profile. Bioorganic & Medicinal Chemistry 24:2, pages 130-139.
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Viviana De Luca, Sonia Del Prete, Vincenzo Carginale, Daniela Vullo, Claudiu T. Supuran & Clemente Capasso. (2015) Cloning, characterization and anion inhibition studies of a γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. Bioorganic & Medicinal Chemistry Letters 25:21, pages 4970-4975.
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Mark P. Thomas & Barry V. L. Potter. (2015)
Discovery and Development of the Aryl
O
-Sulfamate Pharmacophore for Oncology and Women’s Health
. Journal of Medicinal Chemistry 58:19, pages 7634-7658.
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Cenzo Congiu, Valentina Onnis, Alessandro Deplano, Gianfranco Balboni, Nurcan Dedeoglu & Claudiu T. Supuran. (2015) Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity. Bioorganic & Medicinal Chemistry Letters 25:18, pages 3850-3853.
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Daniela Vullo, Viviana De Luca, Sonia Del Prete, Vincenzo Carginale, Andrea Scozzafava, Clemente Capasso & Claudiu T. Supuran. (2015) Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. Bioorganic & Medicinal Chemistry Letters 25:17, pages 3550-3555.
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Cenzo Congiu, Valentina Onnis, Alessandro Deplano, Gianfranco Balboni, Mariangela Ceruso & Claudiu T. Supuran. (2015) Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties. Bioorganic & Medicinal Chemistry 23:17, pages 5619-5625.
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Claudiu T Supuran & Jean-Yves Winum. (2015) Carbonic anhydrase IX inhibitors in cancer therapy: an update. Future Medicinal Chemistry 7:11, pages 1407-1414.
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Poonam Khloya, Mariangela Ceruso, Sita Ram, Claudiu T. Supuran & Pawan K. Sharma. (2015) Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII. Bioorganic & Medicinal Chemistry Letters 25:16, pages 3208-3212.
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Diaa A. Ibrahim, Deena S. Lasheen, Maysoun Y. Zaky, Amany W. Ibrahim, Daniela Vullo, Mariangela Ceruso, Claudiu T. Supuran & Dalal A. Abou El Ella. (2015) Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII. Bioorganic & Medicinal Chemistry 23:15, pages 4989-4999.
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Mariusz Mojzych, Mariangela Ceruso, Anna Bielawska, Krzysztof Bielawski, Emilia Fornal & Claudiu T. Supuran. (2015) New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors. Bioorganic & Medicinal Chemistry 23:13, pages 3674-3680.
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Fadi M. Awadallah, Tamer A. El-Waei, Mona M. Hanna, Safinaz E. Abbas, Mariangela Ceruso, Beyza Ecem Oz, Ozen Ozensoy Guler & Claudiu T. Supuran. (2015) Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives. European Journal of Medicinal Chemistry 96, pages 425-435.
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Murat Bozdag, Fabrizio Carta, Daniela Vullo, Atilla Akdemir, Semra Isik, Cecilia Lanzi, Andrea Scozzafava, Emanuela Masini & Claudiu T. Supuran. (2015) Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action. Bioorganic & Medicinal Chemistry 23:10, pages 2368-2376.
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Daniela Vullo, Viviana De Luca, Sonia Del Prete, Vincenzo Carginale, Andrea Scozzafava, Clemente Capasso & Claudiu T. Supuran. (2015) Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. Bioorganic & Medicinal Chemistry 23:8, pages 1728-1734.
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Fabrizio Carta, Lorenzo Di Cesare Mannelli, Melissa Pinard, Carla Ghelardini, Andrea Scozzafava, Robert McKenna & Claudiu T. Supuran. (2015) A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. Bioorganic & Medicinal Chemistry 23:8, pages 1828-1840.
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Aiga Grandane, Muhammet Tanc, Raivis Žalubovskis & Claudiu T. Supuran. (2015) Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action. Bioorganic & Medicinal Chemistry 23:7, pages 1430-1436.
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Brian P. Mahon, Alex M. Hendon, Jenna M. Driscoll, Gregory M. Rankin, Sally-Ann Poulsen, Claudiu T. Supuran & Robert McKenna. (2015) Saccharin: A lead compound for structure-based drug design of carbonic anhydrase IX inhibitors. Bioorganic & Medicinal Chemistry 23:4, pages 849-854.
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Lāsma Ivanova, Elīna Zandberga, Karīna Siliņa, Zane Kalniņa, Artūrs Ābols, Edgars Endzeliņš, Ineta Vendina, Nadezhda Romanchikova, Alinta Hegmane, Pēteris Trapencieris, Jānis Eglītis & Aija Linē. (2014) Prognostic relevance of carbonic anhydrase IX expression is distinct in various subtypes of breast cancer and its silencing suppresses self-renewal capacity of breast cancer cells. Cancer Chemotherapy and Pharmacology 75:2, pages 235-246.
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