Pharmaceutical Biology, Volume 56, Issue 1 (2018)

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Pharmaceutical Biology, Volume 56, Issue 1 (2018)

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Research Article

Article
Total flavones of Abelmoschus manihot improve diabetic nephropathy by inhibiting the iRhom2/TACE signalling pathway activity in rats
Su Liu, Lifang Ye, Jing Tao, Chao Ge, Liji Huang & Jiangyi Yu
Pages: 1-11
Published online: 08 Dec 2017
AbstractforTotal flavones of Abelmoschus manihot improve diabetic nephropathy by inhibiting the iRhom2/TACE signalling pathway activity in rats | Full Text | References | PDF (3.6 MB)
  • 3692 Views
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Open Access
Article
The effect of aqueous extract of Rosa damascena on formaldehyde-induced toxicity in mice testes
Majid Askaripour, Azam Hasanpour, Foruzan Hosseini, Mojgan Moshrefi, Gholamreza Moshtaghi, Mohammad Hasannejad, Soodeh Rajabi & Seyed Noureddin Nematollahi-Mahani
Pages: 12-17
Published online: 12 Dec 2017
AbstractforThe effect of aqueous extract of Rosa damascena on formaldehyde-induced toxicity in mice testes | Full Text | References | PDF (1.4 MB)
  • 3294 Views
  • 5 CrossRef citations
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Open Access
Article
The α-amylase and α-glucosidase inhibitory activities of the dichloromethane extracts and constituents of Ferulago bracteata roots
Songül Karakaya, Sefa Gözcü, Zühal Güvenalp, Hilal Özbek, Hafize Yuca, Benan Dursunoğlu, Cavit Kazaz & Ceyda Sibel Kılıç
Pages: 18-24
Published online: 12 Dec 2017
AbstractforThe α-amylase and α-glucosidase inhibitory activities of the dichloromethane extracts and constituents of Ferulago bracteata roots | Full Text | References | PDF (783.7 KB)
  • 5163 Views
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Open Access
Article
Adjuvant activity of ethanol extract of Hippophae rhamnoides leaves with inactivated rabies virus antigen
D. Singh, B. Jayashankar, K. P. Mishra, H. Tanwar, S. N. Madhusudana, A. Y. Belludi, R. Tulsawani, S. B. Singh & L. Ganju
Pages: 25-31
Published online: 13 Dec 2017
AbstractforAdjuvant activity of ethanol extract of Hippophae rhamnoides leaves with inactivated rabies virus antigen | Full Text | References | PDF (916.6 KB)
  • 1672 Views
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Open Access
Article
The suppressive effect of the three-herb extract mixture on vascular and liver inflammation in atherogenic diet with high fructose-fed mice
Hae Seong Song, Hyun Jung Koo, Bong Kyun Park, Jeong Eun Kwon, Seon-A Jang, Hyun Jin Baek, Se Young Kim, Sung Ryul Lee & Se Chan Kang
Pages: 32-42
Published online: 18 May 2018
AbstractforThe suppressive effect of the three-herb extract mixture on vascular and liver inflammation in atherogenic diet with high fructose-fed mice | Full Text | References | PDF (3.6 MB)
  • 1617 Views
  • 6 CrossRef citations
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Open Access
Article
Baohuoside-I suppresses cell proliferation and migration by up-regulating miR-144 in melanoma
Ya-Guang Peng & Li Zhang
Pages: 43-50
Published online: 20 Dec 2017
AbstractforBaohuoside-I suppresses cell proliferation and migration by up-regulating miR-144 in melanoma | Full Text | References | PDF (1.7 MB) | Supplemental
  • 1689 Views
  • 16 CrossRef citations
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Open Access
Article
Potential of rare actinomycetes in the production of metabolites against multiple oxidant agents
Fatemeh Mohammadipanah & Mana Momenilandi
Pages: 51-59
Published online: 23 Dec 2017
AbstractforPotential of rare actinomycetes in the production of metabolites against multiple oxidant agents | Full Text | References | PDF (1.8 MB)
  • 2781 Views
  • 18 CrossRef citations
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Open Access
Article
“Not tonight zebrafish”: the effects of Ruta graveolens on reproduction
Mohammad Navid Forsatkar, Maryam HedayatiRad & Ana Carolina Luchiari
Pages: 60-66
Published online: 02 Jan 2018
Abstractfor“Not tonight zebrafish”: the effects of Ruta graveolens on reproduction | Full Text | References | PDF (982.9 KB)
  • 2039 Views
  • 10 CrossRef citations
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Open Access
Article
Comparing coagulation activity of Selaginella tamariscina before and after stir-frying process and determining the possible active constituents based on compositional variation
Qian Zhang, Ya-Li Wang, Die Gao, Liang Cai, Yi-Yao Yang, Yuan-Jia Hu, Feng-Qing Yang, Hua Chen & Zhi-Ning Xia
Pages: 67-75
Published online: 02 Jan 2018
AbstractforComparing coagulation activity of Selaginella tamariscina before and after stir-frying process and determining the possible active constituents based on compositional variation | Full Text | References | PDF (1.8 MB)
  • 1869 Views
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Open Access
Article
Pharmacological effects of Chatuphalatika in hyperuricemia of gout
Vilasinee Hirunpanich Sato, Bunleu Sungthong, Prasob-Orn Rinthong, Narawat Nuamnaichati, Supachoke Mangmool, Savita Chewchida & Hitoshi Sato
Pages: 76-85
Published online: 03 Jan 2018
AbstractforPharmacological effects of Chatuphalatika in hyperuricemia of gout | Full Text | References | PDF (1.2 MB)
  • 3744 Views
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Open Access
Article
S-Nitrosoglutathione formation at gastric pH is augmented by ascorbic acid and by the antioxidant vitamin complex, Resiston
Vitali I. Stsiapura, Ilya Bederman, Ivan I. Stepuro, Tatiana S. Morozkina, Stephen J. Lewis, Laura Smith, Benjamin Gaston & Nadzeya Marozkina
Pages: 86-93
Published online: 03 Jan 2018
AbstractforS-Nitrosoglutathione formation at gastric pH is augmented by ascorbic acid and by the antioxidant vitamin complex, Resiston | Full Text | References | PDF (1.3 MB)
  • 1535 Views
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Open Access
Article
Protective effect of MOTILIPERM in varicocele-induced oxidative injury in rat testis by activating phosphorylated inositol requiring kinase 1α (p-IRE1α) and phosphorylated c-Jun N-terminal kinase (p-JNK) pathways
Kiran Kumar Soni, Li Tao Zhang, Bo Ram Choi, Keshab Kumar Karna, Jae Hyung You, Yu Seob Shin, Sung Won Lee, Chul Young Kim, Chen Zhao, Han-Jung Chae, Hye Kyung Kim & Jong Kwan Park
Pages: 94-103
Published online: 10 Jan 2018
AbstractforProtective effect of MOTILIPERM in varicocele-induced oxidative injury in rat testis by activating phosphorylated inositol requiring kinase 1α (p-IRE1α) and phosphorylated c-Jun N-terminal kinase (p-JNK) pathways | Full Text | References | PDF (1.6 MB)
  • 2183 Views
  • 27 CrossRef citations
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Open Access
Article
Effects of Danshen tablets on pharmacokinetics of atorvastatin calcium in rats and its potential mechanism
Sen Sun, Rong Wang, Jie Fan, Guoqing Zhang & Hai Zhang
Pages: 104-108
Published online: 11 Jan 2018
AbstractforEffects of Danshen tablets on pharmacokinetics of atorvastatin calcium in rats and its potential mechanism | Full Text | References | PDF (772.3 KB)
  • 1908 Views
  • 10 CrossRef citations
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Open Access

Review Article

Review
Mulberry leaves and their potential effects against cardiometabolic risks: a review of chemical compositions, biological properties and clinical efficacy
Thanchanit Thaipitakwong, Surawej Numhom & Pornanong Aramwit
Pages: 109-118
Published online: 18 Jan 2018
AbstractforMulberry leaves and their potential effects against cardiometabolic risks: a review of chemical compositions, biological properties and clinical efficacy | Full Text | References | PDF (909.7 KB)
  • 9947 Views
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Open Access

Research Article

Article
Effects of glycyrrhizin on the pharmacokinetics of asiatic acid in rats and its potential mechanism
Ling Guo, Ying Cui & Kaijun Hao
Pages: 119-123
Published online: 22 Jan 2018
AbstractforEffects of glycyrrhizin on the pharmacokinetics of asiatic acid in rats and its potential mechanism | Full Text | References | PDF (617.4 KB)
  • 1810 Views
  • 14 CrossRef citations
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Open Access
Article
Andrographolide relieved pathological pain generated by spared nerve injury model in mice
Huang-Chi Wang, Hsin-Sheng Tsay, Hui-Nung Shih, Yi-An Chen, Kai-Ming Chang, Dinesh Chandra Agrawal, Siendong Huang, Yi-Lo Lin & Meng-Jen Lee
Pages: 124-131
Published online: 01 Feb 2018
AbstractforAndrographolide relieved pathological pain generated by spared nerve injury model in mice | Full Text | References | PDF (1.8 MB) | Supplemental
  • 1537 Views
  • 9 CrossRef citations
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Open Access
Article
Effects of triptolide on pharmacokinetics of amlodipine in rats by using LC–MS/MS
Chengyin Zhang, Zhiqiang Gao, Lijuan Niu & Xuexun Chen
Pages: 132-137
Published online: 01 Feb 2018
AbstractforEffects of triptolide on pharmacokinetics of amlodipine in rats by using LC–MS/MS | Full Text | References | PDF (946.2 KB)
  • 1778 Views
  • 11 CrossRef citations
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Open Access
Article
The role of artichoke leaf tincture (Cynara scolymus) in the suppression of DNA damage and atherosclerosis in rats fed an atherogenic diet
Natasa Bogavac-Stanojevic, Jelena Kotur Stevuljevic, Darko Cerne, Janja Zupan, Janja Marc, Zorica Vujic, Milkica Crevar-Sakac, Miron Sopic, Jelena Munjas, Miroslav Radenkovic & Zorana Jelic-Ivanovic
Pages: 138-144
Published online: 06 Feb 2018
AbstractforThe role of artichoke leaf tincture (Cynara scolymus) in the suppression of DNA damage and atherosclerosis in rats fed an atherogenic diet | Full Text | References | PDF (834.6 KB)
  • 2026 Views
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Open Access
Article
Metabolomic evaluation of Euphorbia pekinensis induced nephrotoxicity in rats
Zhenzhen Liu, Yan Zeng & Pengyi Hou
Pages: 145-153
Published online: 09 Feb 2018
AbstractforMetabolomic evaluation of Euphorbia pekinensis induced nephrotoxicity in rats | Full Text | References | PDF (1.9 MB)
  • 1318 Views
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Open Access

Invited Article

Article
The predictive utility of the plant phylogeny in identifying sources of cardiovascular drugs
Emily Guzman & Jeanmaire Molina
Pages: 154-164
Published online: 27 Feb 2018
AbstractforThe predictive utility of the plant phylogeny in identifying sources of cardiovascular drugs | Full Text | References | PDF (1.5 MB)
  • 2976 Views
  • 9 CrossRef citations
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Open Access

Research Article

Article
In vivo anti-ulcerogenic effect of okra (Abelmoschus esculentus) on ethanol-induced acute gastric mucosal lesions
Deniz Ortaç, Mustafa Cemek, Turan Karaca, Mehmet E. Büyükokuroğlu, Zafer Ö. Özdemir, Ayşe Tuba Kocaman & Sadık Göneş
Pages: 165-175
Published online: 07 Mar 2018
AbstractforIn vivo anti-ulcerogenic effect of okra (Abelmoschus esculentus) on ethanol-induced acute gastric mucosal lesions | Full Text | References | PDF (4.5 MB)
  • 4070 Views
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Open Access
Article
Protective properties of geniposide against UV-B-induced photooxidative stress in human dermal fibroblasts
Daehyun Shin, Sihyeong Lee, Yu-Hua Huang, Hye-Won Lim, Yoonjin Lee, Kyounghee Jang, Yongwan Cho, Sang Jun Park, Dae-Duk Kim & Chang-Jin Lim
Pages: 176-182
Published online: 09 Mar 2018
AbstractforProtective properties of geniposide against UV-B-induced photooxidative stress in human dermal fibroblasts | Full Text | References | PDF (997.1 KB)
  • 2091 Views
  • 15 CrossRef citations
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Open Access
Article
Desalted Salicornia europaea powder and its active constituent, trans-ferulic acid, exert anti-obesity effects by suppressing adipogenic-related factors
Md. Mahbubur Rahman, Myung-Jin Kim, Jin-Hyoung Kim, Sok-Ho Kim, Hyeon-Kyu Go, Mee-Hyang Kweon & Do-Hyung Kim
Pages: 183-191
Published online: 09 Mar 2018
AbstractforDesalted Salicornia europaea powder and its active constituent, trans-ferulic acid, exert anti-obesity effects by suppressing adipogenic-related factors | Full Text | References | PDF (2.5 MB)
  • 3294 Views
  • 29 CrossRef citations
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Open Access
Article
Anti-neuroinflammatory effects of cudraflavanone A isolated from the chloroform fraction of Cudrania tricuspidata root bark
Kwan-Woo Kim, Tran Hong Quang, Wonmin Ko, Dong-Cheol Kim, Chi-Su Yoon, Hyuncheol Oh & Youn-Chul Kim
Pages: 192-200
Published online: 09 Mar 2018
AbstractforAnti-neuroinflammatory effects of cudraflavanone A isolated from the chloroform fraction of Cudrania tricuspidata root bark | Full Text | References | PDF (1.4 MB)
  • 1605 Views
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Open Access

Invited Article

Article
Antibacterial effects of 18 medicinal plants used by the Khyang tribe in Bangladesh
Md Shahadat Hossan, Hassan Jindal, Sarah Maisha, Chandramathi Samudi Raju, Shamala Devi Sekaran, Veeranoot Nissapatorn, Fatima Kaharudin, Lim Su Yi, Teng Jin Khoo, Mohammed Rahmatullah & Christophe Wiart
Pages: 201-208
Published online: 13 Mar 2018
AbstractforAntibacterial effects of 18 medicinal plants used by the Khyang tribe in Bangladesh | Full Text | References | PDF (818 KB)
  • 11568 Views
  • 33 CrossRef citations
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Open Access

Research Article

Article
Crocin exerts anti-inflammatory and anti-arthritic effects on type II collagen-induced arthritis in rats
Wei Liu, Yufeng Sun, Zhenping Cheng, Yong Guo, Peiming Liu & Ying Wen
Pages: 209-216
Published online: 15 Mar 2018
AbstractforCrocin exerts anti-inflammatory and anti-arthritic effects on type II collagen-induced arthritis in rats | Full Text | References | PDF (1.5 MB) | Supplemental
  • 3047 Views
  • 31 CrossRef citations
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Open Access
Article
Protective effect of compound Danshen (Salvia miltiorrhiza) dripping pills alone and in combination with carbamazepine on kainic acid-induced temporal lobe epilepsy and cognitive impairment in rats
Chen Jia, Shanshan Han, Liming Wei, Xiangji Dang, Qianqian Niu, Mengyu Chen, Boqun Cao, Yuting Liu & Haisheng Jiao
Pages: 217-224
Published online: 21 Mar 2018
AbstractforProtective effect of compound Danshen (Salvia miltiorrhiza) dripping pills alone and in combination with carbamazepine on kainic acid-induced temporal lobe epilepsy and cognitive impairment in rats | Full Text | References | PDF (1.7 MB) | Supplemental
  • 2241 Views
  • 25 CrossRef citations
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Open Access
Article
Vascular mechanisms underlying the hypotensive effect of Rumex acetosa
Hafiz Misbah-Ud-Din Qamar, Rahila Qayyum, Umme Salma, Shamim Khan, Taous Khan & Abdul Jabbar Shah
Pages: 225-234
Published online: 21 Mar 2018
AbstractforVascular mechanisms underlying the hypotensive effect of Rumex acetosa | Full Text | References | PDF (1.8 MB)
  • 1751 Views
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Open Access

Invited Article

Article
Isolation and identification of three new chromones from the leaves of Pimenta dioica with cytotoxic, oestrogenic and anti-oestrogenic effects
Brian J. Doyle, Temitope O. Lawal, Tracie D. Locklear, Lorraina Hernandez, Alice L. Perez, Udeshi Patel, Shitalben Patel & Gail B. Mahady
Pages: 235-244
Published online: 22 Mar 2018
AbstractforIsolation and identification of three new chromones from the leaves of Pimenta dioica with cytotoxic, oestrogenic and anti-oestrogenic effects | Full Text | References | PDF (1.2 MB)
  • 1717 Views
  • 9 CrossRef citations
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Research Article

Article
Zanthoxylum alatum abrogates lipopolysaccharide-induced depression-like behaviours in mice by modulating neuroinflammation and monoamine neurotransmitters in the hippocampus
Chandana Choudhury Barua, Prakash Haloi, Beenita Saikia, Kunjbihari Sulakhiya, Debesh Chandra Pathak, Shantanu Tamuli, Hooriah Rizavi & Xinguo Ren
Pages: 245-252
Published online: 23 Mar 2018
AbstractforZanthoxylum alatum abrogates lipopolysaccharide-induced depression-like behaviours in mice by modulating neuroinflammation and monoamine neurotransmitters in the hippocampus | Full Text | References | PDF (1.1 MB)
  • 2557 Views
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Invited Article

Article
Brazilian medicinal plants with corroborated anti-inflammatory activities: a review
Victor Pena Ribeiro, Caroline Arruda, Mohamed Abd El-Salam & Jairo Kenupp Bastos
Pages: 253-268
Published online: 12 Apr 2018
AbstractforBrazilian medicinal plants with corroborated anti-inflammatory activities: a review | Full Text | References | PDF (1.5 MB)
  • 7048 Views
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Research Article

Article
Effects of diclofenac on the pharmacokinetics of celastrol in rats and its transport
Zengfu Wang, Dali Chen & Zhongwei Wang
Pages: 269-274
Published online: 13 Apr 2018
AbstractforEffects of diclofenac on the pharmacokinetics of celastrol in rats and its transport | Full Text | References | PDF (874.6 KB)
  • 1866 Views
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Open Access
Article
Lipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors
Agnieszka M. Jurga, Ewelina Rojewska, Wioletta Makuch & Joanna Mika
Pages: 275-286
Published online: 16 Apr 2018
AbstractforLipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors | Full Text | References | PDF (3.7 MB)
  • 2237 Views
  • 16 CrossRef citations
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Open Access
Article
Screening of in vitro antimicrobial activity of plants used in traditional Indonesian medicine
Andreas Romulo, Ervizal A. M. Zuhud, Johana Rondevaldova & Ladislav Kokoska
Pages: 287-293
Published online: 16 Apr 2018
AbstractforScreening of in vitro antimicrobial activity of plants used in traditional Indonesian medicine | Full Text | References | PDF (954.5 KB)
  • 7082 Views
  • 31 CrossRef citations
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Open Access
Article
Effects and possible mechanisms of Alpinia officinarum ethanol extract on indomethacin-induced gastric injury in rats
Jingwen Gong, Zhong Zhang, Xuguang Zhang, Feng Chen, Yinfeng Tan, Hailong Li, Jie Jiang & Junqing Zhang
Pages: 294-301
Published online: 21 May 2018
AbstractforEffects and possible mechanisms of Alpinia officinarum ethanol extract on indomethacin-induced gastric injury in rats | Full Text | References | PDF (1.3 MB)
  • 1915 Views
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Open Access
Article
Galangin, a dietary flavonoid, ameliorates hyperglycaemia and lipid abnormalities in rats with streptozotocin-induced hyperglycaemia
Amal A. Aloud, Veeramani Chinnadurai, Chandramohan Govindasamy, Mohammed A. Alsaif & Khalid S. Al-Numair
Pages: 302-308
Published online: 28 Jun 2018
AbstractforGalangin, a dietary flavonoid, ameliorates hyperglycaemia and lipid abnormalities in rats with streptozotocin-induced hyperglycaemia | Full Text | References | PDF (827.3 KB)
  • 2293 Views
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Article
Quercetin promotes gastrointestinal motility and mucin secretion in loperamide-induced constipation of SD rats through regulation of the mAChRs downstream signal
Ji Eun Kim, Mi Rim Lee, Jin Ju Park, Jun Young Choi, Bo Ram Song, Hong Joo Son, Young Whan Choi, Kyung Mi Kim, Jin Tae Hong & Dae Youn Hwang
Pages: 309-317
Published online: 28 Jun 2018
AbstractforQuercetin promotes gastrointestinal motility and mucin secretion in loperamide-induced constipation of SD rats through regulation of the mAChRs downstream signal | Full Text | References | PDF (1.3 MB)
  • 2904 Views
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Article
Antitubercular evaluation of root extract and isolated phytochemicals from Lophira lanceolata against two resistant strains of Mycobacterium tuberculosis
Jeanne Louise Nkot, Dominique Serge Ngono Bikobo, Auguste Abouem A Zintchem, Norbert Mbabi Nyemeck II, Esther Del Florence Moni Ndedi, Patrick Hervé Betote Diboué, Dieudonné Emmanuel Pegnyemb, Christian G. Bochet & Ulrich Koert
Pages: 318-324
Published online: 03 Jul 2018
AbstractforAntitubercular evaluation of root extract and isolated phytochemicals from Lophira lanceolata against two resistant strains of Mycobacterium tuberculosis | Full Text | References | PDF (819.5 KB) | Supplemental
  • 1314 Views
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Article
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice
Yuchuan Wang, Min Guan, Xin Zhao & Xinli Li
Pages: 325-332
Published online: 03 Jul 2018
AbstractforEffects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice | Full Text | References | PDF (972.4 KB)
  • 2970 Views
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Article
Effects of Ginkgo leaf tablets on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism
Baiping Dong, Suowei Yuan, Jinsheng Hu & Yanzhen Yan
Pages: 333-336
Published online: 28 Jun 2018
AbstractforEffects of Ginkgo leaf tablets on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism | Full Text | References | PDF (501.5 KB)
  • 1628 Views
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Article
Effect of citral on mouse hepatic cytochrome P450 enzymes
Huaqiao Tang, Nana Long, Min Dai, Lin Lin, Jianlong Li, Fenghui Sun & Lijuan Guo
Pages: 337-343
Published online: 03 Jul 2018
AbstractforEffect of citral on mouse hepatic cytochrome P450 enzymes | Full Text | References | PDF (914.4 KB)
  • 1345 Views
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Article
Dihydromyricetin improves vascular hyporesponsiveness in experimental sepsis via attenuating the over-excited MaxiK and KATP channels
Jin Peng, Jian Zhang, Li Zhang, Yonggang Tian, Yahong Li & Lujun Qiao
Pages: 344-350
Published online: 13 Jul 2018
AbstractforDihydromyricetin improves vascular hyporesponsiveness in experimental sepsis via attenuating the over-excited MaxiK and KATP channels | Full Text | References | PDF (967.3 KB)
  • 1208 Views
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Article
Influence of andrographolide on the pharmacokinetics of warfarin in rats
Xiaoli Zhang, Xiaosu Zhang, Xiaocui Wang & Meijun Zhao
Pages: 351-356
Published online: 08 Jul 2018
AbstractforInfluence of andrographolide on the pharmacokinetics of warfarin in rats | Full Text | References | PDF (678.1 KB)
  • 3113 Views
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Article
Enhanced production of tanshinone IIA in endophytic fungi Emericella foeniculicola by genome shuffling
Pengyu Zhang, Yiting Lee, Xiying Wei, Jinlan Wu, Qingmei Liu & Shanning Wan
Pages: 357-362
Published online: 28 Sep 2018
AbstractforEnhanced production of tanshinone IIA in endophytic fungi Emericella foeniculicola by genome shuffling | Full Text | References | PDF (672.2 KB)
  • 998 Views
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Article
In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes
Jinlan Wei, Hongying Zhang & Qingling Zhao
Pages: 363-367
Published online: 19 Aug 2018
AbstractforIn vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes | Full Text | References | PDF (696.8 KB)
  • 1277 Views
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Article
Assessing product adulteration of Eurycoma longifolia (Tongkat Ali) herbal medicinal product using DNA barcoding and HPLC analysis
Bashir Mohammed Abubakar, Faezah Mohd Salleh, Mohd Shahir Shamsir Omar & Alina Wagiran
Pages: 368-377
Published online: 28 Jul 2018
AbstractforAssessing product adulteration of Eurycoma longifolia (Tongkat Ali) herbal medicinal product using DNA barcoding and HPLC analysis | Full Text | References | PDF (1.5 MB)
  • 4110 Views
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Article
Mechanisms of butylidenephthalide for twitch facilitation in electrically stimulated mouse vas deferens
Chung-Hung Shih, Chi-Ming Chen & Wun-Chang Ko
Pages: 378-384
Published online: 19 Aug 2018
AbstractforMechanisms of butylidenephthalide for twitch facilitation in electrically stimulated mouse vas deferens | Full Text | References | PDF (951.7 KB)
  • 701 Views
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Article
Adaptation of a microbead assay for the easy evaluation of traditional anti-sickling medicines: application to DREPANOSTAT and FACA
Joran Villaret, Guillaume Marti, Frédérique Dubois, Karine Reybier, Noémie Gaudre, Mohamed Haddad & Alexis Valentin
Pages: 385-392
Published online: 28 Sep 2018
AbstractforAdaptation of a microbead assay for the easy evaluation of traditional anti-sickling medicines: application to DREPANOSTAT and FACA | Full Text | References | PDF (956.9 KB)
  • 1087 Views
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Article
Bioinformatics analysis to identify action targets in NCI-N87 gastric cancer cells exposed to quercetin
Yun Zeng, Zhengjie Shen, Wenzhe Gu & Mianhua Wu
Pages: 393-398
Published online: 28 Sep 2018
AbstractforBioinformatics analysis to identify action targets in NCI-N87 gastric cancer cells exposed to quercetin | Full Text | References | PDF (763.4 KB) | Supplemental
  • 1585 Views
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Article
Some pharmacokinetic parameters of salvianolic acid A following single-dose oral administration to rats
Jialin Sun, Junke Song, Wen Zhang, Fanbo Jing, Wen Xu, Ping Leng, Xianghua Quan, Guanhua Du & Zhongguo Sui
Pages: 399-406
Published online: 19 Aug 2018
AbstractforSome pharmacokinetic parameters of salvianolic acid A following single-dose oral administration to rats | Full Text | References | PDF (1 MB)
  • 1236 Views
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Article
3,3′-Diindolylmethane enhances apoptosis in docetaxel-treated breast cancer cells by generation of reactive oxygen species
Susan Lanza-Jacoby & Guanjun Cheng
Pages: 407-414
Published online: 10 Oct 2018
Abstractfor3,3′-Diindolylmethane enhances apoptosis in docetaxel-treated breast cancer cells by generation of reactive oxygen species | Full Text | References | PDF (1.5 MB)
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Researh Article

Article
Anti-inflammatory effects of shikonin in human periodontal ligament cells
Chen Fan, Xufang Zhang & Zee Upton
Pages: 415-421
Published online: 04 Nov 2018
AbstractforAnti-inflammatory effects of shikonin in human periodontal ligament cells | Full Text | References | PDF (1.1 MB)
  • 1661 Views
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Research Article

Article
Dicranopteris linearis extract inhibits the proliferation of human breast cancer cell line (MDA-MB-231) via induction of S-phase arrest and apoptosis
Aifaa Akmal Baharuddin, Rushduddin Al Jufri Roosli, Zainul Amiruddin Zakaria & Siti Farah Md. Tohid
Pages: 422-432
Published online: 10 Oct 2018
AbstractforDicranopteris linearis extract inhibits the proliferation of human breast cancer cell line (MDA-MB-231) via induction of S-phase arrest and apoptosis | Full Text | References | PDF (2.7 MB)
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Article
Effects of psoralen on the pharmacokinetics of anastrozole in rats
Yuzhu Zhang, Jingjing Wu, Yue Zhou, Yulian Yin & Hongfeng Chen
Pages: 433-439
Published online: 21 Oct 2018
AbstractforEffects of psoralen on the pharmacokinetics of anastrozole in rats | Full Text | References | PDF (745.6 KB)
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Article
Resveratrol mitigates the oxidative stress mediated by hypoxic-ischemic brain injury in neonatal rats via Nrf2/HO-1 pathway
Yan Gao, Rongrong Fu, Jue Wang, Xue Yang, Lulu Wen & Juan Feng
Pages: 440-449
Published online: 21 Nov 2018
AbstractforResveratrol mitigates the oxidative stress mediated by hypoxic-ischemic brain injury in neonatal rats via Nrf2/HO-1 pathway | Full Text | References | PDF (1.3 MB)
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Short Communication

Rapid Communication
Safranal-promoted differentiation and survival of dopaminergic neurons in an animal model of Parkinson’s disease
Yi Zhao & Gangming Xi
Pages: 450-454
Published online: 24 Oct 2018
AbstractforSafranal-promoted differentiation and survival of dopaminergic neurons in an animal model of Parkinson’s disease | Full Text | References | PDF (750.6 KB)
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Research Article

Article
Mangosteen ethanol extract alleviated the severity of collagen-induced arthritis in rats and produced synergistic effects with methotrexate
Jian Zuo, Qin Yin, Lin Wang, Wen Zhang, Yan Fan, Yu-Yan Zhou, Yan Li & Guo-Dong Wang
Pages: 455-464
Published online: 04 Dec 2018
AbstractforMangosteen ethanol extract alleviated the severity of collagen-induced arthritis in rats and produced synergistic effects with methotrexate | Full Text | References | PDF (1.9 MB) | Supplemental
  • 1904 Views
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Review Article

Review
A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis
Zi-Long Wang, Shuang Wang, Yi Kuang, Zhi-Min Hu, Xue Qiao & Min Ye
Pages: 465-484
Published online: 05 Dec 2018
AbstractforA comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis | Full Text | References | PDF (2.3 MB)
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Review
Echinacea biotechnology: advances, commercialization and future considerations
Jessica L. Parsons, Stewart I. Cameron, Cory S. Harris & Myron L. Smith
Pages: 485-494
Published online: 10 Oct 2018
AbstractforEchinacea biotechnology: advances, commercialization and future considerations | Full Text | References | PDF (1.1 MB)
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Research Article

Article
Assessing the effect of Mentha longifolia essential oils on COX-2 expression in animal model of sepsis induced by caecal ligation and puncture
Abolfazl Dadkhah, Faezeh Fatemi, Azadeh Rasooli, Mohammad Reza Mohammadi Malayeri & Fatemeh Torabi
Pages: 495-504
Published online: 04 Dec 2018
AbstractforAssessing the effect of Mentha longifolia essential oils on COX-2 expression in animal model of sepsis induced by caecal ligation and puncture | Full Text | References | PDF (1.3 MB)
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Article
Bioactive metabolites from the leaves of Withania adpressa
Widad Ben Bakrim, Laila El Bouzidi, Jean-Marc Nuzillard, Sylvian Cretton, Noémie Saraux, Aymeric Monteillier, Philippe Christen, Muriel Cuendet & Khalid Bekkouche
Pages: 505-510
Published online: 17 Nov 2018
AbstractforBioactive metabolites from the leaves of Withania adpressa | Full Text | References | PDF (1.1 MB) | Supplemental
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Article
Effect of simvastatin on the SIRT2/NF-κB pathway in rats with acute pulmonary embolism
Zhi-Yao Wu, Hui Li & Yong-Jun Tang
Pages: 511-518
Published online: 03 Dec 2018
AbstractforEffect of simvastatin on the SIRT2/NF-κB pathway in rats with acute pulmonary embolism | Full Text | References | PDF (1.1 MB)
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Article
Synthesis, characterization and evaluation of transfection efficiency of dexamethasone conjugated poly(propyleneimine) nanocarriers for gene delivery#
Bizhan Malaekeh-Nikouei, Mehdi Rezaee, Leila Gholami, Naghmeh Sanjar Mousavi & Reza Kazemi Oskuee
Pages: 519-527
Published online: 30 Sep 2018
AbstractforSynthesis, characterization and evaluation of transfection efficiency of dexamethasone conjugated poly(propyleneimine) nanocarriers for gene delivery# | Full Text | References | PDF (1.4 MB)
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Article
Green synthesis of selenium nanoparticles with extract of hawthorn fruit induced HepG2 cells apoptosis
Dongxiao Cui, Tingting Liang, Liqian Sun, Liqiang Meng, Congcong Yang, Liwei Wang, Taigang Liang & Qingshan Li
Pages: 528-534
Published online: 02 Nov 2018
AbstractforGreen synthesis of selenium nanoparticles with extract of hawthorn fruit induced HepG2 cells apoptosis | Full Text | References | PDF (1,015.3 KB)
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Article
Crataegus aronia enhances sperm parameters and preserves testicular architecture in both control and non-alcoholic fatty liver disease-induced rats
Mohammad Dallak
Pages: 535-547
Published online: 30 Oct 2018
AbstractforCrataegus aronia enhances sperm parameters and preserves testicular architecture in both control and non-alcoholic fatty liver disease-induced rats | Full Text | References | PDF (1.9 MB)
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Article
Phylogenetic analysis of Uncaria species based on internal transcribed spacer (ITS) region and ITS2 secondary structure
Shuang Zhu, Qiwei Li, Shanchong Chen, Yesheng Wang, Lin Zhou, Changqing Zeng & Jun Dong
Pages: 548-558
Published online: 04 Nov 2018
AbstractforPhylogenetic analysis of Uncaria species based on internal transcribed spacer (ITS) region and ITS2 secondary structure | Full Text | References | PDF (1.4 MB) | Supplemental
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Article
Spasmolytic activity of Aquilariae Lignum Resinatum extract on gastrointestinal motility involves muscarinic receptors, calcium channels and NO release
Huimin Li, Yanfei Qu, Jiawei Zhang, Jingze Zhang & Wenyuan Gao
Pages: 559-566
Published online: 05 Dec 2018
AbstractforSpasmolytic activity of Aquilariae Lignum Resinatum extract on gastrointestinal motility involves muscarinic receptors, calcium channels and NO release | Full Text | References | PDF (1.4 MB)
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Article
Mechanism of TangGanJian on nonalcoholic fatty liver disease with type 2 diabetes mellitus
Yanbo Fan, Wei Xiong, Jingjing Li, Aimin Hu, Zhiwei He, Jiawen Zhang, Guoyun Zhou & Qiang Yin
Pages: 567-572
Published online: 21 Nov 2018
AbstractforMechanism of TangGanJian on nonalcoholic fatty liver disease with type 2 diabetes mellitus | Full Text | References | PDF (833.7 KB)
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Article
Wenshen Yangxue decoction improves endometrial receptivity recovery and promotes endometrial angiogenesis in a rat model
Mingwei Xin, Junqin He, Wei Yang, Xiaodan Yin & Jingshang Wang
Pages: 573-579
Published online: 11 Dec 2018
AbstractforWenshen Yangxue decoction improves endometrial receptivity recovery and promotes endometrial angiogenesis in a rat model | Full Text | References | PDF (1.3 MB)
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Article
Ma Huang Tang ameliorates bronchial asthma symptoms through the TLR9 pathway
Jiayuan Jiao, Jiming Wu, Jiali Wang, Yaping Guo, Le Gao, Honggang Liang, Jian Huang & Jinhui Wang
Pages: 580-593
Published online: 11 Nov 2018
AbstractforMa Huang Tang ameliorates bronchial asthma symptoms through the TLR9 pathway | Full Text | References | PDF (4.7 MB) | Supplemental
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Review Article

Review
Molecular mechanism and research progress on pharmacology of traditional Chinese medicine in liver injury
Hong Yang Zhang, Hong Ling Wang, Guo Yue Zhong & Ji Xiao Zhu
Pages: 594-611
Published online: 04 Dec 2018
AbstractforMolecular mechanism and research progress on pharmacology of traditional Chinese medicine in liver injury | Full Text | References | PDF (3.4 MB)
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Research Article

Article
Ethanol extract of Schisandrae chinensis fructus ameliorates the extent of experimentally induced atherosclerosis in rats by increasing antioxidant capacity and improving endothelial dysfunction
Xiu Chen, Jiahong Cao, Yong Sun, Yaolan Dai, Jiali Zhu, Xuemei Zhang, Xiaoqin Zhao, Liwen Wang, Tingting Zhao, Yongbiao Li, Youping Liu, Guihua Wei, Tiane Zhang & Zhiyong Yan
Pages: 612-619
Published online: 04 Dec 2018
AbstractforEthanol extract of Schisandrae chinensis fructus ameliorates the extent of experimentally induced atherosclerosis in rats by increasing antioxidant capacity and improving endothelial dysfunction | Full Text | References | PDF (1.5 MB)
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Article
In vitro inhibitory effects of bergenin on human liver cytochrome P450 enzymes
Gang Dong, Yun Zhou & Xiaoli Song
Pages: 620-625
Published online: 04 Dec 2018
AbstractforIn vitro inhibitory effects of bergenin on human liver cytochrome P450 enzymes | Full Text | References | PDF (1.1 MB)
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Article
In vivo protective effects of chlorogenic acid against triptolide-induced hepatotoxicity and its mechanism
Jun-Ming Wang, Rong-Xing Chen, Lu-Lu Zhang, Ning-Ning Ding, Chen Liu, Ying Cui & Yong-Xian Cheng
Pages: 626-631
Published online: 17 Dec 2018
AbstractforIn vivo protective effects of chlorogenic acid against triptolide-induced hepatotoxicity and its mechanism | Full Text | References | PDF (1.5 MB)
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Article
Anti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model
Gwang-Mo Shin, Sushruta Koppula, Yun-Jin Chae, Hyun-Su Kim, Jae-Dong Lee, Myong-Ki Kim & MinDong Song
Pages: 632-642
Published online: 04 Dec 2018
AbstractforAnti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model | Full Text | References | PDF (2.2 MB)
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Article
Metabonomics of d-glucaro-1,4-lactone in preventing diethylnitrosamine-induced liver cancer in rats
Wenlong Yang, Guanlin Zhou, Shubing Zou, Wentao Yang, Aihong Liu, Shuilin Sun & Baogang Xie
Pages: 643-648
Published online: 11 Dec 2018
AbstractforMetabonomics of d-glucaro-1,4-lactone in preventing diethylnitrosamine-induced liver cancer in rats | Full Text | References | PDF (1.3 MB)
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Articles

Article
Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation
Hai Zhang, Qing-Cuo Ren, Yan Ren, Lin Zhao, Fan Yang, Yi Zhang, Wen-Ji Zhao, Yu-Zhu Tan & Xiao-Fei Shen
Pages: 649-657
Published online: 13 Dec 2018
AbstractforAjudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation | Full Text | References | PDF (2.2 MB) | Supplemental
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Research Article

Article
Antiproliferative and cytotoxic activities of furocoumarins of Ducrosia anethifolia
Javad Mottaghipisheh, Márta Nové, Gabriella Spengler, Norbert Kúsz, Judit Hohmann & Dezső Csupor
Pages: 658-664
Published online: 17 Dec 2018
AbstractforAntiproliferative and cytotoxic activities of furocoumarins of Ducrosia anethifolia | Full Text | References | PDF (740 KB) | Supplemental
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Article
Berberine inhibits angiogenesis in glioblastoma xenografts by targeting the VEGFR2/ERK pathway
Fa Jin, Tao Xie, Xiaoguang Huang & Xinde Zhao
Pages: 665-671
Published online: 02 Jan 2019
AbstractforBerberine inhibits angiogenesis in glioblastoma xenografts by targeting the VEGFR2/ERK pathway | Full Text | References | PDF (1 MB)
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Article
Effect of hydroalcoholic Echium amoenum extract on scopolamine-induced learning and memory impairment in rats
Zahra Rabiei & Mahbubeh Setorki
Pages: 672-677
Published online: 12 Dec 2018
AbstractforEffect of hydroalcoholic Echium amoenum extract on scopolamine-induced learning and memory impairment in rats | Full Text | References | PDF (959 KB)
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Articles

Article
Evaluation of the potential nephrotoxicity and mechanism in rats after long-term exposure to the traditional Tibetan medicine tsothel
Li Xiang, Bo Lin, Ping Wang, Yingfan Hu, Jiasi Wu, Yong Zeng & Xianli Meng
Pages: 678-690
Published online: 17 Dec 2018
AbstractforEvaluation of the potential nephrotoxicity and mechanism in rats after long-term exposure to the traditional Tibetan medicine tsothel | Full Text | References | PDF (4.5 MB)
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